William Berger

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 27:214-23. 2006
  2. ncbi The reliability, validity, and preliminary responsiveness of the Eye Allergy Patient Impact Questionnaire (EAPIQ)
    Michael Alexander
    Niagara Clinical Research, 5673 North Street, Niagara Falls, Ont L2G1J4, Canada
    Health Qual Life Outcomes 3:67. 2005
  3. ncbi Treatment of persistent asthma with Symbicort (budesonide/formoterol inhalation aerosol): an inhaled corticosteroid and long-acting beta2-adrenergic agonist in one pressurized metered-dose inhaler
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691 6410, USA
    J Asthma 47:447-59. 2010
  4. ncbi Treatment of allergic rhinitis and other immunoglobulin E-mediated diseases with anti-immunoglobulin E antibody
    William E Berger
    Mission Viejo Medical Center, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 27:S29-32. 2006
  5. ncbi The safety and efficacy of desloratadine for the management of allergic disease
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Drug Saf 28:1101-18. 2005
  6. ncbi Paediatric pulmonary drug delivery: considerations in asthma treatment
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, CA 92691 6410, USA
    Expert Opin Drug Deliv 2:965-80. 2005
  7. ncbi Effects of adjuvant therapy with 0.1% olopatadine hydrochloride ophthalmic solution on quality of life in patients with allergic rhinitis using systemic or nasal therapy
    William Berger
    Southern California Research, Mission Viejo, California, USA
    Ann Allergy Asthma Immunol 95:361-71. 2005
  8. ncbi Budesonide inhalation suspension for the treatment of asthma in infants and children
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691 6410, USA
    Drugs 65:1973-89. 2005
  9. ncbi The use of inhaled formoterol in the treatment of asthma
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691 6410, USA
    Ann Allergy Asthma Immunol 97:24-33. 2006
  10. ncbi Impact of azelastine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis
    William Berger
    Southern California Research, Mission Viejo 92691, USA
    Ann Allergy Asthma Immunol 97:375-81. 2006

Detail Information

Publications58

  1. ncbi Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 27:214-23. 2006
    ..All treatments were well tolerated. Desloratadine, 5 mg, and fexofenadine, 180 mg, provide comparable efficacy and tolerability in the treatment of SAR. Both treatments are significantly more effective than placebo...
  2. ncbi The reliability, validity, and preliminary responsiveness of the Eye Allergy Patient Impact Questionnaire (EAPIQ)
    Michael Alexander
    Niagara Clinical Research, 5673 North Street, Niagara Falls, Ont L2G1J4, Canada
    Health Qual Life Outcomes 3:67. 2005
    ..The purpose of this study was to present the results of the psychometric validation of the EAPIQ...
  3. ncbi Treatment of persistent asthma with Symbicort (budesonide/formoterol inhalation aerosol): an inhaled corticosteroid and long-acting beta2-adrenergic agonist in one pressurized metered-dose inhaler
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691 6410, USA
    J Asthma 47:447-59. 2010
    ..The objective was to review efficacy, safety, and pharmacogenetic data on budesonide/formoterol pMDI in the treatment of persistent asthma...
  4. ncbi Treatment of allergic rhinitis and other immunoglobulin E-mediated diseases with anti-immunoglobulin E antibody
    William E Berger
    Mission Viejo Medical Center, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 27:S29-32. 2006
    ....
  5. ncbi The safety and efficacy of desloratadine for the management of allergic disease
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Drug Saf 28:1101-18. 2005
    ..In addition, it has been shown to not interact with concomitantly administered drugs and food. Overall, current data indicate that desloratadine is a safe and effective treatment for allergic diseases...
  6. ncbi Paediatric pulmonary drug delivery: considerations in asthma treatment
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, CA 92691 6410, USA
    Expert Opin Drug Deliv 2:965-80. 2005
    ..Although age-based device recommendations have been made, the optimal choice for drug delivery is the one that the patient or caregiver prefers to use, can use correctly and is most likely to use consistently...
  7. ncbi Effects of adjuvant therapy with 0.1% olopatadine hydrochloride ophthalmic solution on quality of life in patients with allergic rhinitis using systemic or nasal therapy
    William Berger
    Southern California Research, Mission Viejo, California, USA
    Ann Allergy Asthma Immunol 95:361-71. 2005
    ..The Rhinoconjunctivitis Quality of Life Questionnaire and the Allergic Conjunctivitis Quality of Life Questionnaire quantify separate aspects of QoL...
  8. ncbi Budesonide inhalation suspension for the treatment of asthma in infants and children
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691 6410, USA
    Drugs 65:1973-89. 2005
    ..However, available evidence suggests that growth effects are transient in children receiving budesonide and that these children eventually achieve full adult height...
  9. ncbi The use of inhaled formoterol in the treatment of asthma
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691 6410, USA
    Ann Allergy Asthma Immunol 97:24-33. 2006
    ..To discuss the clinical efficacy and safety of formoterol when used to relieve symptoms of asthma and prevent exercise-induced bronchoconstriction (EIB)...
  10. ncbi Impact of azelastine nasal spray on symptoms and quality of life compared with cetirizine oral tablets in patients with seasonal allergic rhinitis
    William Berger
    Southern California Research, Mission Viejo 92691, USA
    Ann Allergy Asthma Immunol 97:375-81. 2006
    ....
  11. ncbi Effects of treatment with mometasone furoate dry powder inhaler in children with persistent asthma
    William E Berger
    Allergy and Asthma Associates, Mission Viejo, California 92691, USA
    Ann Allergy Asthma Immunol 97:672-80. 2006
    ..Mometasone furoate dry powder inhaler (DPI) has been shown to effectively treat asthma in children...
  12. ncbi Efficacy and safety of formoterol for the treatment of chronic obstructive pulmonary disease
    W E Berger
    Allergy and Asthma Associates of Southern California, 27800 Medical Asthma Associates, Suite 244, Mission Viejo, CA 92691, USA
    Respir Med 102:173-88. 2008
    ....
  13. ncbi Once-daily olopatadine ophthalmic solution 0.2% in the treatment of allergic conjunctivitis and rhinoconjunctivitis
    William E Berger
    Clinical Professor, Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, CA, USA Allergy and Asthma Associates, 27800 Medical Center Road, Suite 244, Mission Viejo, CA 92691, USA
    Expert Rev Pharmacoecon Outcomes Res 7:221-6. 2007
    ..This review article will summarize literature reports on the 0.2% formulation of olopatadine from the standpoint of efficacy, safety, total treatment costs, therapeutic outcomes, patient compliance and effect on quality of life...
  14. ncbi Efficacy and safety of budesonide/formoterol pressurized metered-dose inhaler: randomized controlled trial comparing once- and twice-daily dosing in patients with asthma
    William E Berger
    Allergy and Asthma Associates, 27800 Medical Center Road, Mission Viejo, CA 92691, USA
    Allergy Asthma Proc 31:49-59. 2010
    ..Once- or twice-daily BUD/FM showed better efficacy than BUD once daily or PBO; results generally were more favorable with twice-daily dosing compared with both once-daily dosing regimens, which had one-half the daily FM dose...
  15. ncbi The safety and clinical benefit of budesonide/formoterol pressurized metered-dose inhaler versus budesonide alone in children
    William E Berger
    Allergy and Asthma Associates of Southern California, 27800 Medical Center Road Number 244, Mission Viejo, CA 29691 6410, USA
    Allergy Asthma Proc 31:26-39. 2010
    ..007). In this 26-week study of asthmatic children (6-11 years), safety profiles were similar and clinical benefits were greater with budesonide/formoterol than with budesonide...
  16. ncbi Safety and efficacy of olopatadine hydrochloride nasal spray 0.6% in pediatric subjects with allergic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Allergy Asthma Proc 30:612-23. 2009
    ..In subjects 6 to <12 years of age, OLO was superior to vehicle in the treatment of SAR. In subjects 2 to <12 years of age, OLO had an overall low rate of AEs and low systemic exposure...
  17. ncbi Aerosol devices and asthma therapy
    William Berger
    Allergy and Asthma Associates of Southern CA, 27800 Medical Center Road, Suite 244, Mission Viejo, CA 92691 6410, USA
    Curr Drug Deliv 6:38-49. 2009
    ....
  18. ncbi Pharmacokinetic characteristics and safety and tolerability of a reformulated azelastine hydrochloride nasal spray in patients with chronic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, USA
    Expert Opin Drug Metab Toxicol 5:91-102. 2009
    ....
  19. ncbi Ciclesonide: a closer look at its systemic and oropharyngeal safety profile
    William E Berger
    Allergy and Asthma Associates, 27800 Medical Center Road, Mission Viejo, CA 92691, USA
    Curr Drug Saf 1:265-70. 2006
    ..The favorable safety profile of ciclesonide suggests a conferred benefit to asthma patients treated with this novel ICS...
  20. ncbi Mometasone furoate/formoterol in the treatment of persistent asthma
    William E Berger
    Allergy and Asthma Associates, 27800 Medical Center Road, Suite 244, Mission Viejo, CA, USA
    Expert Rev Respir Med 5:739-46. 2011
    ..Clinical safety studies lasting up to 1 year have found that MF/F has a low incidence of local and systemic side effects...
  21. ncbi Safety of budesonide inhalation suspension in infants aged six to twelve months with mild to moderate persistent asthma or recurrent wheeze
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, CA 92691, USA
    J Pediatr 146:91-5. 2005
    ..To compare the safety of budesonide inhalation suspension (BIS) with placebo in infants 6 to 12 months of age with mild to moderate persistent asthma or recurrent wheeze...
  22. ncbi Levalbuterol: pharmacologic properties and use in the treatment of pediatric and adult asthma
    William E Berger
    Southern California Research, Mission Viejo, California 92691, USA
    Ann Allergy Asthma Immunol 90:583-91; quiz 591-2, 659. 2003
    ..To review the rationale supporting the use of levalbuterol [(R)-albuterol] for the treatment of pediatric and adult asthma...
  23. ncbi Triamcinolone acetonide aqueous nasal spray and fluticasone propionate are equally effective for relief of nasal symptoms in patients with seasonal allergic rhinitis
    William E Berger
    Southern California Research, Mission Viejo, USA
    Otolaryngol Head Neck Surg 129:16-23. 2003
    ..Nasal symptom (discharge, stuffiness, itching, sneezing) severity was recorded twice daily; total nasal symptom score was calculated. Health-related quality of life was assessed by Rhinoconjunctivitis Quality of Life Questionnaire...
  24. ncbi Overview of allergic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Ann Allergy Asthma Immunol 90:7-12. 2003
    ..Half the patients with allergic rhinitis experience symptoms up to 4 months per year, whereas 20% are symptomatic more than 9 months of the year. This disease is often associated with asthma, sinusitis, and otitis media...
  25. ncbi Treatment of acute bronchospasm in elderly patients
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, College of Medicine, University of California, Irvine, USA
    Postgrad Med 118:34-7; discussion 38. 2005
    ..This paper presents results from clinical studies examining levalbuterol and racemic albuterol use among elderly patients who have asthma or COPD...
  26. ncbi Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion
    William E Berger
    Southern California Research, Mission Viejo, California 92691, USA
    Ann Allergy Asthma Immunol 89:485-91. 2002
    ..A nonsedating antihistamine that significantly decreases nasal congestion and improves symptoms of seasonal allergic asthma would be a significant advance in therapy...
  27. ncbi Efficacy and safety of fluticasone propionate 250 microg administered once daily in patients with persistent asthma treated with or without inhaled corticosteroids
    William E Berger
    Ann Allergy Asthma Immunol 89:393-9. 2002
    ..Studies have shown fluticasone propionate (FP) 100, 200, and 500 microg administered once daily to be effective in the treatment of asthma. The efficacy of a once daily regimen of FP 250 microg has not been evaluated previously...
  28. ncbi Allergic rhinitis in children
    W E Berger
    Allergy and Asthma Associates, 27800 Medical Center Road, Suite 244, Mission Viejo, CA 92691, USA
    Curr Allergy Asthma Rep 1:498-505. 2001
    ....
  29. ncbi Monoclonal anti-IgE antibody: a novel therapy for allergic airways disease
    William E Berger
    Southern California Research, Mission Viejo 92691, USA
    Ann Allergy Asthma Immunol 88:152-60; quiz 161-2, 208. 2002
    ..To anticipate the likely effects (efficacy and safety) in clinical use in patients with allergic asthma and with allergic rhinitis. To characterize the types of patients who might benefit from this therapy...
  30. ncbi Allergic rhinitis in children : diagnosis and management strategies
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, California, USA
    Paediatr Drugs 6:233-50. 2004
    ....
  31. ncbi Efficacy of azelastine nasal spray in patients with an unsatisfactory response to loratadine
    William E Berger
    Southern California Research Center, Mission Viejo, California 92691, USA
    Ann Allergy Asthma Immunol 91:205-11. 2003
    ....
  32. ncbi Evaluation of long-term safety of the anti-IgE antibody, omalizumab, in children with allergic asthma
    William Berger
    Mission Viejo Medical Center, Mission Viejo, California, USA
    Ann Allergy Asthma Immunol 91:182-8. 2003
    ..To evaluate the long-term effects of the anti-IgE antibody omalizumab in children with asthma...
  33. ncbi One-year efficacy and safety of inhaled formoterol dry powder in children with persistent asthma
    George Bensch
    Georgetown Place, Stockton, California, USA
    Ann Allergy Asthma Immunol 89:180-90. 2002
    ..However, this treatment requires close disease monitoring to detect early signs of acute exacerbation...
  34. ncbi Evaluation of levalbuterol metered dose inhaler in pediatric patients with asthma: a double-blind, randomized, placebo- and active-controlled trial
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, CA, USA
    Curr Med Res Opin 22:1217-26. 2006
    ..CONCLUSIONS: In this study, levalbuterol administered via MDI significantly improved airway function in comparison with placebo in asthmatic children aged 4-11 years with a safety profile that was similar to placebo...
  35. ncbi Effect of once-daily fluticasone furoate nasal spray on nasal symptoms in adults and adolescents with perennial allergic rhinitis
    Robert A Nathan
    Allergy and Asthma Associates, PC, Colorado Springs, Colorado 80907, USA
    Ann Allergy Asthma Immunol 100:497-505. 2008
    ..Intranasal corticosteroids are recommended as first-line therapy for the treatment of allergic rhinitis. Fluticasone furoate is a novel enhanced-affinity glucocorticoid for the treatment of allergic rhinitis...
  36. ncbi A patient satisfaction survey comparing levalbuterol with racemic albuterol in children
    William E Berger
    Southern California Research, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 25:437-44. 2004
    ..This study supports the conclusion that the majority of caregivers of children with asthma who have experience with both levalbuterol and racemic albuterol prefer levalbuterol over racemic albuterol...
  37. ncbi Mometasone furoate improves congestion in patients with moderate-to-severe seasonal allergic rhinitis
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, University of California, Irvine, 92691, USA
    Ann Pharmacother 39:1984-9. 2005
    ..A recent survey estimated that 85% of patients with allergic rhinitis experience nasal congestion. This symptom considerably impacts quality of life...
  38. ncbi Acute bronchospasm from the patient's perspective
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, College of Medicine, University of California, Irvine, USA
    Postgrad Med 118:44-7; discussion 48. 2005
    ..These research studies point out that a very real "communications gap" exists between physicians and patients when examined from the patient's perspective...
  39. ncbi Current options in the treatment of acute bronchospasm
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, College of Medicine, University of California, Irvine, USA
    Postgrad Med 118:18-26. 2005
    ..Better control allows for better patient health, reduced number of physician and emergency department visits, and reduced health care costs...
  40. ncbi Asthma and COPD: definitions, epidemiology, and treatment guidelines
    William E Berger
    Department of Pediatrics, Division of Allergy and Immunology, College of Medicine, University of California, Irvine, USA
    Postgrad Med 118:2-8. 2005
    ..Prevalence of asthma may be leveling off. Prevalence of COPD is increasing, especially in women. Although several therapies are available, many patients do not seek treatment until COPD is moderately advanced...
  41. ncbi Efficacy and safety evaluation of ciclesonide in subjects with mild-to-moderate asthma not currently using inhaled corticosteroids
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California, USA
    Allergy Asthma Proc 30:304-14. 2009
    ..In this study, CIC80 b.i.d. improved disease control in subjects with mild-to-moderate persistent asthma not using an ICS and provided greater improvements than CIC160 q.d...
  42. ncbi Intranasal corticosteroids: the development of a drug delivery device for fluticasone furoate as a potential step toward improved compliance
    William E Berger
    Allergy and Asthma Associates, 27800 Medical Center Road, Suite 244, Mission Viejo, California 92691, USA
    Expert Opin Drug Deliv 4:689-701. 2007
    ..Findings suggest that the FF system should aid in improving attitudes to the use of intranasal corticosteroids amongst physicians and patients...
  43. ncbi The use of inhaled corticosteroids for persistent asthma in infants and young children
    William E Berger
    Allergy and Asthma Associates of Southern California, Mission Viejo, California 92691, USA
    Ann Allergy Asthma Immunol 92:387-399; quiz 399-402, 463. 2004
    ..To review pediatric trials of inhaled corticosteroid (ICS) therapy and summarize data on the pediatric use of devices to facilitate delivery of ICSs...
  44. ncbi What is new in antiimmunoglobulin E asthma therapy
    William E Berger
    Allergy and Asthma Associates, Mission Viejo Medical Center, Mission Viejo, California 92691, USA
    Allergy Asthma Proc 26:428-34. 2005
    ....
  45. ncbi The utility of the Health Plan Employer Data and Information Set (HEDIS) asthma measure to predict asthma-related outcomes
    William E Berger
    American College of Allergy, Asthma, and Immunology, Mission Viejo, California, USA
    Ann Allergy Asthma Immunol 93:538-45. 2004
    ..37; 95% CI, 0.05-2.69). CONCLUSIONS: Our findings suggest that refinements to the HEDIS measure method for identifying patients with persistent asthma may be needed...
  46. ncbi Pediatric allergic rhinitis: antihistamine selection
    William E Berger
    Allergy/Asthma Associates, Mission Viejo, California 92691, USA
    Clin Pediatr (Phila) 44:655-64. 2005
  47. ncbi Access to allergy care: implications for quality healthcare and public safety
    William E Berger
    Southern California Research, Mission Viejo, CA, USA
    Manag Care Q 11:8-11. 2003
    ..Any action to reduce or limit coverage will not only diminish the quality of medical care for allergy patients but have significant health and safety implications for the general public...
  48. ncbi Judicious antibiotic use and intranasal corticosteroids in acute rhinosinusitis
    Catherine Butkus Small
    Division of Infectious Diseases, Department of Medicine, New York Medical College, Westchester Medical Center, Valhalla 10595, USA
    Am J Med 120:289-94. 2007
    ..The use of intranasal corticosteroids in acute rhinosinusitis therefore might reduce the inappropriate use of antimicrobial therapy in acute rhinosinusitis...
  49. ncbi The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis
    George Philip
    Merck Research Laboratories, Rahway, NJ, USA
    Curr Med Res Opin 20:1549-58. 2004
    ..005). CONCLUSION: Montelukast provides significant relief from symptoms of seasonal allergic rhinitis, while also conferring a benefit for asthma, in patients with both allergic rhinitis and asthma...
  50. ncbi Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma
    Carlos E Baena-Cagnani
    Department of Paediatrics, Infantile Hospital, Santa Rosa, Cordoba, Argentina
    Int Arch Allergy Immunol 130:307-13. 2003
    ..Asthma and seasonal allergic rhinitis (SAR) are recognized as manifestations of a single airway disease. Desloratadine has demonstrated efficacy in treating SAR symptoms, including nasal obstruction...
  51. ncbi Comparison of the efficacy of combined fluticasone propionate and olopatadine versus combined fluticasone propionate and fexofenadine for the treatment of allergic rhinoconjunctivitis induced by conjunctival allergen challenge
    Bob Q Lanier
    Fort Worth Allergy Asthma Association, Texas 76132, USA
    Clin Ther 24:1161-74. 2002
    ....
  52. ncbi Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine
    Craig F LaForce
    Carolina Allergy and Asthma Consultants, Raleigh, North Carolina 27607, USA
    Ann Allergy Asthma Immunol 93:154-9. 2004
    ..Currently available oral second-generation antihistamines do not provide adequate symptom relief for many allergy patients...
  53. ncbi Evaluation of comfort using olopatadine hydrochloride 0.1% ophthalmic solution in the treatment of allergic conjunctivitis in contact lens wearers compared to placebo using the conjunctival allergen-challenge model
    Miguel Brodsky
    Opthalmology Department, Israelita Medical Hospital, Buenos Aires, Argentina
    Eye Contact Lens 29:113-6. 2003
    ....
  54. ncbi Safety and efficacy of olopatadine hydrochloride nasal spray for the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California 92123, USA
    Ann Allergy Asthma Immunol 95:600-6. 2005
    ..A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR)...
  55. ncbi Once-daily ciclesonide improves lung function and is well tolerated by patients with mild-to-moderate persistent asthma
    David S Pearlman
    Colorado Allergy and Asthma Centers, PC, Denver 80230, USA
    J Allergy Clin Immunol 116:1206-12. 2005
    ..Inhaled corticosteroids are recommended as first-line therapy for persistent asthma...
  56. ncbi Direct and indirect costs of asthma to an employer
    Howard G Birnbaum
    Analysis Group/Economics, Cambridge, MA 02138, USA
    J Allergy Clin Immunol 109:264-70. 2002
    ..CONCLUSION: Failure to account fully for the broader consequences of asthma in terms of indirect and comorbid treatment costs would result in a significant underassessment of the cost of asthma to an employer...
  57. ncbi The variability of asthma
    Kevin R Murphy
    Midwest Children s Chest Physicians, Omaha, NE 68130, USA
    Curr Med Res Opin 21:1519-26. 2005
    ..Awareness of episodic changes in asthma severity, with subsequent tailored adjustment in guideline-based ICS therapy, should enable optimal control of asthma with minimal medication requirements...
  58. ncbi Symptom severity assessment of allergic rhinitis: part 1
    Sheldon L Spector
    Ann Allergy Asthma Immunol 91:105-14. 2003