Detail Information
Publications
A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methodsHenrik Bengtsson
Department of Statistics, Life Sciences Division, University of California, Lawrence Berkeley National Laboratory, Berkeley, USA
Bioinformatics 25:861-7. 2009..This is the reason why it is not straightforward to combine CN estimates from different sources (platforms, labs and analysis methods)...
A single-array preprocessing method for estimating full-resolution raw copy numbers from all Affymetrix genotyping arrays including GenomeWideSNP 5 & 6Henrik Bengtsson
Department of Statistics, University of California, Berkeley, California, USA
Bioinformatics 25:2149-56. 2009..This shows that it is possible to do online analysis in large-scale projects where additional arrays are introduced over time...
TumorBoost: normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarraysHenrik Bengtsson
Department of Statistics, University of California, Berkeley, USA
BMC Bioinformatics 11:245. 2010..Even after state of the art preprocessing methods, allelic signal estimates from genotyping arrays still suffer from systematic effects that make them difficult to use effectively for such downstream analyses...
Parent-specific copy number in paired tumor-normal studies using circular binary segmentationAdam B Olshen
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
Bioinformatics 27:2038-46. 2011..The raw data from such experiments are two-dimensional, but are unphased. Consequently, inference based on them necessitates development of new analytic methods...
