Research Topics
| Ahmi Ben-YehudahSummaryAffiliation: University of Pittsburgh Country: USA Publications
| Collaborators
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Detail Information
Publications
Systems biology discoveries using non-human primate pluripotent stem and germ cells: novel gene and genomic imprinting interactions as well as unique expression patternsAhmi Ben-Yehudah
Pittsburgh Development Center, 204 Craft Avenue, Pittsburgh, PA 15213, USA
Stem Cell Res Ther 1:24. 2010..In this review, we consider the mRNAs and novel genes with unique expression and imprinting patterns that were discovered using systems biology approaches with primate pluripotent stem and germ cells...
Pluripotency genes overexpressed in primate embryonic stem cells are localized on homologues of human chromosomes 16, 17, 19, and XAhmi Ben-Yehudah
Pittsburgh Development Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Stem Cell Res 4:25-37. 2010....
Establishment and characterization of baboon embryonic stem cell lines: an Old World Primate model for regeneration and transplantation researchCalvin R Simerly
Division of Developmental and Regenerative Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA
Stem Cell Res 2:178-87. 2009..They have been grown continuously for >430 and 290 days, respectively. Teratomas from both lines have all three germ layers. Availabilities of these BabESCs represent another important resource for stem cell biologists...
Semiquantitative histopathology and 3D magnetic resonance microscopy as collaborative platforms for tissue identification and comparison within teratomas derived from pedigreed primate embryonic stem cellsCarlos A Castro
Pittsburgh Development Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Stem Cell Res 5:201-11. 2010..MRM provides rapid quantitative imaging of intact teratomas that complements histology and identifies sites of interest for additional biological studies...
mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cellsCharles A Easley
Pittsburgh Development Center, Magee Womens Research Institute and Foundation, Pittsburgh, Pennsylvania, USA
Cell Reprogram 12:263-73. 2010..These results suggest that hESCs tightly regulate mTORC1/p70 S6K-mediated protein translation to maintain a pluripotent state as well as implicate a novel role for protein synthesis as a driving force behind hESC differentiation...
Specific dynamic and noninvasive labeling of pancreatic beta cells in reporter miceAhmi Ben-Yehudah
Pittsburgh Development Center, Magee Women s Research Institute, Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA
Genesis 43:166-74. 2005..This innovative method of visualizing beta cells will be a useful tool in the study of both beta cell physiology and the development of the endocrine cells of the pancreas...
WNT5A is a regulator of fibroblast proliferation and resistance to apoptosisLouis J Vuga
Dorothy P and Richard P Simmons Center for Interstitial Lung Diseases, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Am J Respir Cell Mol Biol 41:583-9. 2009..Collectively, our data suggest that WNT5A may play a role in fibroblast expansion and survival characteristics of idiopathic pulmonary fibrosis and other fibrotic interstitial lung diseases that exhibit UIP histological patterns...
Evaluating protocols for embryonic stem cell differentiation into insulin-secreting beta-cells using insulin II-GFP as a specific and noninvasive reporterAhmi Ben-Yehudah
Department of Obstetrics, Gynecology, and Reproductive Sciences, Pittsburgh Development Center, Magee Womens Research Institute and Foundation, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Cloning Stem Cells 11:245-57. 2009..Therefore, improved beta-cells differentiation protocols are needed, and these insulin II GFP cells may prove to be an important tool to accelerate this process...
Pedigreed primate embryonic stem cells express homogeneous familial gene profilesChristopher S Navara
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh Development Center, Magee Womens Research Institute and Foundation, Pittsburgh, Pennsylvania, USA
Stem Cells 25:2695-704. 2007..These similarities to mouse ESCs suggest that heterogeneities found among hESCs likely result from their disparate origins rather than intrinsic biological limitations with primate embryonic stem cells...
Inhibition and role of let-7d in idiopathic pulmonary fibrosisKusum V Pandit
University of Pittsburgh Medical Center, NW 628 MUH, 3459 5th Avenue, Pittsburgh, PA 15261, USA
Am J Respir Crit Care Med 182:220-9. 2010..Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal fibrotic lung disease characterized by profound changes in epithelial cell phenotype and fibroblast proliferation...
Derivation and characterization of nonhuman primate embryonic stem cellsChristopher S Navara
University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Curr Protoc Stem Cell Biol . 2007..With these protocols, the investigator will be able to isolate nhpES cells and perform the necessary tests to confirm the pluripotent phenotype...
