Research Topics
Species | CAREY DAVID BALABANSummaryAffiliation: University of Pittsburgh Country: USA Publications
Research Grants
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Publications
Migraine, vertigo and migrainous vertigo: Links between vestibular and pain mechanismsCarey D Balaban
Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA
J Vestib Res 21:315-21. 2011....
Rizatriptan reduces vestibular-induced motion sickness in migraineursJoseph M Furman
Department of Otolaryngology, Eye and Ear Institute, University of Pittsburgh School of Medicine, 203 Lothrop Street, Pittsburgh, PA 15213, USA
J Headache Pain 12:81-8. 2011..We conclude that the serotonin agonist, rizatriptan, reduces vestibular-induced motion sickness by influencing serotonergic vestibular-autonomic projections...
Neurologic bases for comorbidity of balance disorders, anxiety disorders and migraine: neurotherapeutic implicationsCarey D Balaban
University of Pittsburgh, PA, USA
Expert Rev Neurother 11:379-94. 2011....
Toward revitalizing the role of physician-scientists in academic medicineCarey D Balaban
Departments of Otolaryngology, Neurobiology, Communication Sciences and Disorders, and Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, USA
Otolaryngol Head Neck Surg 139:766-8. 2008....
Zonal organization of flocculo-vestibular connections in ratsC D Balaban
Departments of Otolaryngology and Neurobiology, University of Pittsburgh, Eye and Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15213, USA
Neuroscience 99:669-82. 2000....
Three distinct categories of time course of pain produced by oral capsaicinCarey D Balaban
Departments of Otolaryngology, Neurobiology and Communication Sciences, Eye and Ear Institute, School of Medicine, Pittsburgh, Pennsylvania 15213, USA
J Pain 6:315-22. 2005..These time-dependent analyses provide a new dimension to understanding individual differences in pain sensation in clinical settings...
Projections from the parabrachial nucleus to the vestibular nuclei: potential substrates for autonomic and limbic influences on vestibular responsesCarey D Balaban
Departments of Otolaryngology and Neurobiology, Eye and Ear Institute, University of Pittsburgh, 203 Lothrop Street, Pittsburgh, PA 15213, USA
Brain Res 996:126-37. 2004....
Vestibular nucleus projections to the Edinger-Westphal and anteromedian nuclei of rabbitsCarey D Balaban
Department of Otolaryngology, University of Pittsburgh, Eye and Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15213, USA
Brain Res 963:121-31. 2003..The projections to ChAT-negative (and weakly immunoreactive) cells in AM, VTA and EW, on the other hand, are likely to contribute vestibular signals to a variety of motor responses via descending pathways...
Role of gene regulation during vestibular compensation: an integrative approachC D Balaban
Department of Otolaryngology, University of Pittsburgh, Eye and Ear Institute, Pennsylvania 15213, USA
Ann N Y Acad Sci 942:52-64. 2001..Specifically, one must consider the roles of transcriptional, translational, and posttranslational events on the turnover of critical signaling substrates for vestibular compensation...
Type 1 vanilloid receptor expression by mammalian inner ear ganglion cellsCarey D Balaban
Department of Otolaryngology, University of Pittsburgh School of Medicine, 203 Lothrop Street, Eye and Ear Institute, Rm 153, Pittsburgh, PA 15213, USA
Hear Res 175:165-70. 2003..In particular, these data suggest that LOX activation during inflammatory processes or during cyclo-oxygenase inhibition (e.g. by aspirin) is a potential intrinsic source of VR1 activation in inner ear ganglia...
Neural substrates linking balance control and anxietyCarey D Balaban
Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA
Physiol Behav 77:469-75. 2002..This updated neurologic model continues to be a synthetic schema for investigating the neurological and neurochemical bases for comorbidity of balance disorders and anxiety disorders...
Responses of primate caudal parabrachial nucleus and Kölliker-fuse nucleus neurons to whole body rotationCarey D Balaban
Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Neurophysiol 88:3175-93. 2002....
Tonic, phasic, and integrator components of psychophysical responses to topical capsaicin account for differences of location and sexWilliam R Lariviere
Department of Anesthesiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Pain 6:777-81. 2005..A similarly derived model might prove useful for the analysis of development of chronic pain...
Migrainous vertigo: development of a pathogenetic model and structured diagnostic interviewJoseph M Furman
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Curr Opin Neurol 16:5-13. 2003..This review refines recently proposed diagnostic criteria for migraine-related vestibular symptoms, and develops a pathophysiological model for the interface between migraine and the vestibular system...
Regional distribution of manganese superoxide dismutase 2 (Mn SOD2) expression in rodent and primate spiral ganglion cellsYu Lan Mary Ying
Department of Otolaryngology, University of Pittsburgh, 200 Lothrop Street, Suite 500, Pittsburgh, PA 15213, USA
Hear Res 253:116-24. 2009..These findings suggest that spiral ganglion cell responses to ROS exposure may vary along cochlear spiral with lower response capacity at cochlear base contributing to cumulative susceptibility to high frequency hearing loss...
Selective anterograde tracing of nonserotonergic projections from dorsal raphe nucleus to the basal forebrain and extended amygdalaAdam L Halberstadt
Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Chem Neuroanat 35:317-25. 2008....
Parabrachial nucleus neuronal responses to off-vertical axis rotation in macaquesCYRUS H MCCANDLESS
Department of Neurobiology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Exp Brain Res 202:271-90. 2010....
Temporal interactions between oral irritants: piperine, zingerone, and capsaicinMark A Affeltranger
Department of Psychology, 107 Eye and Ear Institute, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Chem Senses 32:455-62. 2007..These responses were also predicted by a mathematical model of central processing of primary afferent responses...
Localization of the mitochondrial uncoupling protein family in the rat inner earTadashi Kitahara
Department of Otolaryngology, University of Pittsburgh School of Medicine, 107 Eye and Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15123, USA
Hear Res 196:39-48. 2004..Therefore, it is suggested that mitochondrial UCPs (UCP2, UCP3, UCP4) may play both a protective role against oxidative damage and a thermal signaling role in the eighth nerve...
Changes in transient receptor potential cation channel superfamily V (TRPV) mRNA expression in the mouse inner ear ganglia after kanamycin challengeTadashi Kitahara
Department of Otolaryngology, University of Pittsburgh School of Medicine, 107 Eye and Ear Institute, Room 153, 203 Lothrop Street, Pittsburgh, PA 15213, USA
Hear Res 201:132-44. 2005..It is proposed that up-regulated TRPV1 expression during KM exposure may promote ganglion cell survival by contributing to neuronal depolarization, with KM-induced tinnitus and dizziness as consequences...
Distribution of 5-HT1B and 5-HT1D receptors in the inner earSeong Ki Ahn
Department of Otolaryngology, School of Medicine, Gyeongsang National University, and University Hospital Jinju, Korea
Brain Res 1346:92-101. 2010....
Hypoplasia of spiral and Scarpa's ganglion cells in GABA(A) receptor beta(3) subunit knockout miceJa Won Koo
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Hear Res 167:71-80. 2002....
Gentamicin uptake in the chinchilla inner earPamela Roehm
Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Hear Res 230:43-52. 2007....
A heuristic model of sensory adaptationDonald H McBurney
University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Atten Percept Psychophys 71:1941-61. 2009....
Tonic and phasic processes in the acute effects of alcoholChristopher S Martin
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA
Exp Clin Psychopharmacol 14:209-18. 2006..Tonic-phasic modeling allows individual and group differences in the acute effects of alcohol to be studied as time-dynamic processes...
Effect of trans-bullar gentamicin treatment on guinea pig angular and linear vestibulo-ocular reflexesGavin E G Jones
Department of Defense Spatial Orientation Center, Otolaryngology Department, Naval Medical Center, San Diego, 34800 Bob Wilson Dr. Ste 200, CA 92134, San Diego, USA
Exp Brain Res 152:293-306. 2003..It is suggested that these effects indicate selective cytotoxic and/or physiologic effects of gentamicin intoxication in the inner ear or, possibly, the vestibular nerve and central nervous system...
Research Grants
- VESTIBULO-CEREBELLAR CIRCUITSCarey Balaban; Fiscal Year: 2007..Finally, anatomical studies in rats will test specific hypotheses regarding the organization of collateralized noradrenergic projections to the vestibular nuclei and other sites. ..
- VESTIBULO-CEREBELLAR CIRCUITSCarey Balaban; Fiscal Year: 2002..6) The autonomic effects of anterior lobe stimulation are mediated through connections with the vestibular nuclear autonomic regions. ..
- VESTIBULO-CEREBELLAR CIRCUITSCAREY DAVID BALABAN; Fiscal Year: 2010..Hence, the experiments will shed new light of mechanisms accounting for the co-morbidity of vertigo/dizziness and migraine symptoms in patients. ..
