Research Topics
Species | B BadieSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Microglia cyclooxygenase-2 activity in experimental gliomas: possible role in cerebral edema formationBehnam Badie
Department of Neurological Surgery, University of Wisconsin School of Medicine, Madison, Wisconsin 53792, USA
Clin Cancer Res 9:872-7. 2003..To examine the role of inflammatory cells in brain edema formation, we studied the expression cyclooxygenase (COX)-2, a key enzyme in arachidonic acid metabolism, by microglia in the C6 rodent glioma model...
Differential expression of MHC class II and B7 costimulatory molecules by microglia in rodent gliomasBehnam Badie
Neuro Oncology Laboratory, K3 805 Clinical Science Center, Department of Neurological Surgery, University of Wisconsin, School of Medicine, Madison, WI 53792 3232, USA
J Neuroimmunol 133:39-45. 2002..We conclude that microglia immune activity may be suppressed in gliomas and directly correlates to the immunogenecity of experimental brain tumors...
Endoscopic and minimally invasive microsurgical approaches for treating brain tumor patientsBehnam Badie
Department of Neurological Surgery, University of Wisconsin, Madison, WI 53792, USA
J Neurooncol 69:209-19. 2004..As noninvasive therapeutic alternative become available, future neurosurgeons will be challenged to develop effective and less invasive surgical approaches for the diagnosis and treatment of patients will brain tumors...
Expression of Fas ligand by microglia: possible role in glioma immune evasionB Badie
Neuro Oncology Laboratory, Department of Neurological Surgery, University of Wisconsin School of Medicine, K3 805 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3232, USA
J Neuroimmunol 120:19-24. 2001..These observations suggest that microglia are a major source of FasL expression in brain tumors and possibly contribute to the local immunosuppressive milieu of malignant gliomas...
Role of microglia in glioma biologyB Badie
Neuro Oncology Laboratory, Department of Neurological Surgery, University of Wisconsin School of Medicine, Madison, Wisconsin 53792, USA
Microsc Res Tech 54:106-13. 2001..A better understanding of microglia-glioma interaction will be helpful in designing novel immune-based therapies against these fatal tumors...
Use of titanium mesh for reconstruction of large anterior cranial base defectsB Badie
Department of Neurological Surgery, University of Wisconsin, Madison, USA
J Neurosurg 93:711-4. 2000..Patients with large dural defects may need temporary CSF diversion to avoid postoperative fistula formation...
Dexamethasone-induced abolition of the inflammatory response in an experimental glioma model: a flow cytometry studyB Badie
Department of Neurological Surgery, University of Wisconsin School of Medicine, Madison 53792 3232, USA
J Neurosurg 93:634-9. 2000..To characterize the effects of steroids on the central nervous system's response to tumors more clearly, flow cytometry was used to quantify the extent of inflammatory cell infiltration in an immunogenic rat glioma model...
Impaired capacity for upregulation of MHC class II in tumor-associated microgliaJill M Schartner
Department of Neurological Surgery, University of Wisconsin School of Medicine, Madison, WI 53792-3232, USA
Glia 51:279-85. 2005..Understanding the mechanism of these differences may be critical in the development of novel immunotherapies for malignant glioma...
Functional MR imaging assessment of a non-responsive brain injured patientC H Moritz
Department of Radiology, University of Wisconsin, Madison, WI, USA
Magn Reson Imaging 19:1129-32. 2001..These results indicate that fMRI examinations may provide a useful evaluation for brain function in non-responsive brain trauma patients...
Diffusion tensor eigenvector directional color imaging patterns in the evaluation of cerebral white matter tracts altered by tumorAaron S Field
Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792 3252, USA
J Magn Reson Imaging 20:555-62. 2004..To categorize the varied appearances of tumor-altered white matter (WM) tracts on diffusion tensor eigenvector directional color maps...
Drug-induced iatrogenic intraparenchymal hemorrhageSamir Lapsiwala
Department of Neurosurgery, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, H4 3 CSC, Madison, WI 53792, USA
Neurosurg Clin N Am 13:299-312, v-vi. 2002..IPH accounts for 8% to 13% of all stroke cases and is associated with the highest mortality rate...
Combined radiation and p53 gene therapy of malignant glioma cellsB Badie
Department of Neurological Surgery, University of Wisconsin School of Medicine, Madison 53792 3232, USA
Cancer Gene Ther 6:155-62. 1999..We conclude that responses to p53 gene therapy are variable among gliomas and most likely depend upon both cellular p53 status and as yet ill-defined downstream pathways involving activation of cell cycle regulatory and apoptotic genes...
Microglia function in brain tumorsJyoti J Watters
Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53792-3232, USA
J Neurosci Res 81:447-55. 2005..A better understanding of microglia and macrophage function is essential for the development of immune-based treatment strategies against malignant brain tumors...
Supplementary motor area activation in patients with frontal lobe tumors and arteriovenous malformationsJanet Sailor
Department of Radiology, University of Wisconsin Medical School, Madison, Wisconsin, 53792, USA
AJNR Am J Neuroradiol 24:1837-42. 2003..Differences between patients and controls were statistically significant. CONCLUSION: A lesion that contacts or overlaps the SMA is associated with an increased functional MR imaging response within the contralateral SMA...
Preoperative mapping of the supplementary motor area in patients harboring tumors in the medial frontal lobeLindsey Nelson
Department of Radiology, University of Wisconsin School of Medicine, Madison, Wisconsin 53792, USA
J Neurosurg 97:1108-14. 2002....
Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasmBrian P Witwer
Department ofNeurological Surgery, University of Wisconsin School of Medicine, Madison 53792, USA
J Neurosurg 97:568-75. 2002..Whether resection of these involved fibers results in subtle postoperative neurological deficits requires further systematic study...
Diffusion tensor imaging of the corticospinal tract before and after mass resection as correlated with clinical motor findings: preliminary dataBryan J Laundre
Department of Radiology, University of Wisconsin Medical School, Madison, WI 53792-3252, USA
AJNR Am J Neuroradiol 26:791-6. 2005..Further study is warranted to define the role of DTI in planning tumor resections and predicting postoperative motor function...
White matter reorganization after surgical resection of brain tumors and vascular malformationsM Lazar
Laboratory for Brain Imaging and Behavior, The Waisman Center, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705, USA
AJNR Am J Neuroradiol 27:1258-71. 2006..Further studies with intraoperative correlation are necessary to confirm these initial findings and to determine WMT utility for presurgical planning and evaluation of surgical treatments...
Reliability of functional MR imaging with word-generation tasks for mapping Broca's areaJ H Brannen
Department of Radiology, University of Wisconsin, Madison, USA
AJNR Am J Neuroradiol 22:1711-8. 2001..CONCLUSION: fMR imaging with word-generation tasks produces technically satisfactory maps of Broca's area, which localize the area accurately and reliably...
Evaluation of a signal intensity mask in the interpretation of functional MR imaging activation mapsRoberta M Strigel
Department of Radiology, University of Wisconsin, Madison, 53792-3252, USA
AJNR Am J Neuroradiol 26:578-84. 2005..The availability of the SIM may affect interpretation of the fMRI...
Regulation of IL-10 expression by upstream stimulating factor (USF-1) in glioma-associated microgliaLeying Zhang
Department of Neurosurgery, Beckman Research Institute, City of Hope National Medical Center, CA 91010, USA
J Neuroimmunol 184:188-97. 2007..These findings suggest that USF-1 may play a role in IL-10 regulation in MG/MP in brain tumors...
Internalization of MWCNTs by microglia: possible application in immunotherapy of brain tumorsBabak Kateb
Brain Tumor Program, Department of Neurosurgery, 1500 East Duarte Road, Duarte, CA 91010, USA
Neuroimage 37:S9-17. 2007..This study suggests MWCNTs could be used as a novel, non-toxic, and biodegradable nano-vehicles for targeted therapy in brain cancers. Further studies are needed to demonstrate the full capacity of MWCNTs as nanovectors...
