Research Topics
| Misha Miroslav BackonjaSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Use of anticonvulsants for treatment of neuropathic painMisha Miroslav Backonja
Department of Neurology, University of Wisconsin Hospital and Clinics, Room H6 574, 600 Highland Avenue, Madison, WI 53792 5132, USA
Neurology 59:S14-7. 2002..Evidence supporting the efficacy of anticonvulsants in treatment of such pain is evolving. Additional clinical trials should provide information that will better define their role in neuropathic pain...
Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trialM Backonja
Department of Neurology, University of Wisconsin, Madison 53792, USA
JAMA 280:1831-6. 1998..Pain is the most disturbing symptom of diabetic peripheral neuropathy. As many as 45% of patients with diabetes mellitus develop peripheral neuropathies...
Quantitative sensory testing in measurement of neuropathic pain phenomena and other sensory abnormalitiesMiroslav Misha Backonja
Department of Neurology, University of Wisconsin Madison, 600 Highland Avenue, Madison, WI 53792, USA
Clin J Pain 25:641-7. 2009..Together with the companion manuscript, this review provides definitions that should help further the use of QST as a diagnostic tool as well...
NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind studyMiroslav Backonja
University of Wisconsin Madison, Madison, WI 53792, USA
Lancet Neurol 7:1106-12. 2008..We report the results of a randomised, double blind, 12-week study of the efficacy and safety of one application of NGX-4010 in patients with PHN...
Rational multidrug therapy in the treatment of neuropathic painMisha Miroslav Backonja
Department of Neurology, University of Wisconsin Madison, 53792, USA
Curr Pain Headache Rep 10:34-8. 2006..MDT for neuropathic pain is based on a comprehensive clinical neuropathic pain assessment and ongoing monitoring of the drug therapy's efficacy and adverse effects, administering one drug at the time...
Neuropathic pain symptoms relative to overall pain ratingMisha Miroslav Backonja
Department of Neurology, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
J Pain 5:491-7. 2004..Further research of this type can contribute to advances in mechanism-based diagnosis and treatment...
Neuromodulating drugs for the symptomatic treatment of neuropathic painMiroslav Backonja
University of Wisconsin Hospital, Department of Neurology H6 570, 600 Highland Avenue, Madison, WI 53792, USA
Curr Pain Headache Rep 8:212-6. 2004..A number of available anticonvulsants are undergoing clinical trials and many drugs with neuromodulatory properties are being considered for further development...
Neuropathic pain questionnaire--short formMisha-Miroslav Backonja
Department of Neurology, University of Wisconsin, Madison, Wisconsin 53792, USA
Clin J Pain 19:315-6. 2003
Defining neuropathic painMisha Miroslav Backonja
Department of Neurology, University of Wisconsin Medical School, University of Wisconsin, Madison 53792, USA
Anesth Analg 97:785-90. 2003....
Anticonvulsants (antineuropathics) for neuropathic pain syndromesM M Backonja
Department of Neurology, University of Wisconsin, Madison, USA
Clin J Pain 16:S67-72. 2000..More advances in our understanding of the mechanisms underlying neuropathic pain syndromes should further our opportunities to establish the role of anticonvulsants in the treatment of neuropathic pain...
Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trialsMiroslav Backonja
Department of Neurology, Anesthesiology, and Rehabilitation Medicine, University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792, USA
Clin Ther 25:81-104. 2003..Tricyclic antidepressants are considered first-line agents for neuropathic pain, but their use is limited by unwanted side effects and a risk of cardiovascular mortality...
Anticonvulsants for the treatment of neuropathic pain syndromesMiroslav Backonja
University of Wisconsin Hospital, Department of Neurology H6 570, 600 Highland Avenue, Madison, WI 53792, USA
Curr Pain Headache Rep 7:39-42. 2003..This article is an evidence-based summary of randomized clinical trials published in peer-reviewed journals regarding the efficacy of anticonvulsants for the treatment of neuropathic pain...
Individual differences in the effects of perceived controllability on pain perception: critical role of the prefrontal cortexTim V Salomons
University of Wisconsin Madison, WI, USA
J Cogn Neurosci 19:993-1003. 2007....
NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled study with an open-label extensionMisha Miroslav Backonja
University of Wisconsin Madison, Madison, Wisconsin, USA
Pain Med 11:600-8. 2010..To assess the efficacy, tolerability, and safety of NGX-4010, a high-concentration capsaicin dermal patch (capsaicin 640 microg/cm(2), 8%) in patients with postherpetic neuralgia (PHN)...
Development of a neuropathic pain questionnaireSteven J Krause
Department of Orthopedics and Rehabilitation Medicine, University of Wisconsin, Madison, Wisconsin, USA
Clin J Pain 19:306-14. 2003..Consequently, it can be used for monitoring of neuropathic pain treatments and as an outcome measure...
Classification of patients with pain based on neuropathic pain symptoms: comparison of an artificial neural network against an established scoring systemMichael Behrman
Department of Mathematics, University of Wisconsin Madison, Madison, WI, USA
Eur J Pain 11:370-6. 2007..Data analysis with ANNs provides a framework that extends what current approaches offer, especially for dynamic data, such as the rating of pain descriptors over time...
Mechanistic stratification of antineuralgic agentsAhmad Beydoun
Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Pain Symptom Manage 25:S18-30. 2003....
Pain ratings at the thresholds are necessary for interpretation of quantitative sensory testingKiesa Getz Kelly
Department of Neurology, University of Wisconsin, 600 Highland Avenue, Madison, Wisconsin 53792, USA
Muscle Nerve 32:179-84. 2005..Suggestions are provided for combining threshold information for innocuous and noxious stimuli and related pain ratings for the evaluation of sensory nervous system function and, specifically, neuropathic pain...
Pharmacologic management part 1: better-studied neuropathic pain diseasesMisha-Miroslav Backonja
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA
Pain Med 5:S28-47. 2004..Looking to the future, emerging therapies, such as pregabalin and newer N-methyl-D-aspartate-receptor blockers, may provide physicians and patients with new treatment options for more effective relief of pain...
Pharmacologic management part 2: lesser-studied neuropathic pain diseasesMisha-Miroslav Backonja
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA
Pain Med 5:S48-59. 2004....
Voluntary facial displays of pain increase suffering in response to nociceptive stimulationTim V Salomons
Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, Wisconsin 53705, USA
J Pain 9:443-8. 2008..This suggests that exaggerated facial displays of pain, although often socially reinforced, may also have unintended aversive consequences...
A randomized, double-masked, placebo-controlled pilot trial of extended IV lidocaine infusion for relief of ongoing neuropathic painIvo W Tremont-Lukats
Department of Neurology, University of Wisconsin-Madison, Madison, WI 53792, USA
Clin J Pain 22:266-71. 2006..Additional research is needed using higher infusion rates with larger sample sizes to confirm these results and to explore the role of MEGX in the relief of neuropathic pain...
Perceived controllability modulates the neural response to painTim V Salomons
W. M. Keck Laboratory for Functional Brain Imaging and Behavior, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA
J Neurosci 24:7199-203. 2004....
Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studiesDaniel K Kajdasz
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA
Clin Ther 29:2536-46. 2007....
Long-term use of controlled-release oxycodone for noncancer pain: results of a 3-year registry studyRussell K Portenoy
Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, New York, NY 10003, USA
Clin J Pain 23:287-99. 2007..To evaluate the outcomes associated with the use of controlled-release (CR) oxycodone for up to 3 years in the treatment of noncancer pain...
Consensus guidelines: treatment planning and options. Diabetic peripheral neuropathic painCharles E Argoff
New York University School of Medicine and Cohn Pain Management Center, North Shore University Hospital, Manhasset, NY, USA
Mayo Clin Proc 81:S12-25. 2006..Ultimately, treatment choice must also Include consideration of adverse effects, individual patient factors such as comorbidities, and often cost...
Assessment: use of epidural steroid injections to treat radicular lumbosacral pain: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyCarmel Armon
Division of Neurology, Baystate Medical Center, Springfield, MA, USA
Neurology 68:723-9. 2007....
New perspectives on the management of diabetic peripheral neuropathic painTroels S Jensen
Department of Endocrinology, Diabetology and Nutrition, Hôpital Jean Verdier APHP Paris Nord University, Bondy, France
Diab Vasc Dis Res 3:108-19. 2006..Irrespective of which treatment is offered, only about one third of patients are likely to achieve more than 50% pain relief. Further research to improve the diagnosis and management of DPNP is needed...
Quantitative sensory testing for spinal cord stimulation in patients with chronic neuropathic painElon Eisenberg
Pain Relief Unit, Rambam Medical Center, Haifa Pain Research Group, Technion Israel Institute of Technology, Haifa, Israel
Pain Pract 6:161-5. 2006..Participants: Thirteen patients with radicular leg pain due to failed back surgery syndrome (FBSS) or leg pain due to complex regional pain syndrome (CRPS) who were candidates for SCS...
Assessment: use of epidural steroid injections to treat radicular lumbosacral pain: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyWilliam M Landau
Neurology 69:614; author reply 614-5. 2007
