Samuel V AngiuoliSummaryAffiliation: University of Maryland Country: USA Publications
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Detail Information
Publications
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related speciesClaudio Donati
Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
Genome Biol 11:R107. 2010..Streptococcus pneumoniae is one of the most important causes of microbial diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed and compared with strains of non-pathogenic streptococci of the Mitis group...
Toward an online repository of Standard Operating Procedures (SOPs) for (meta)genomic annotationSamuel V Angiuoli
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
OMICS 12:137-41. 2008..In addition, there is no central repository to store and disseminate procedures and protocols for genome annotation. We highlight the importance of SOPs for genome annotation and endorse an online repository of SOPs...
Resources and costs for microbial sequence analysis evaluated using virtual machines and cloud computingSamuel V Angiuoli
Institute for Genome Sciences, University of Maryland Baltimore, Baltimore, Maryland, United States of America
PLoS ONE 6:e26624. 2011..Cloud computing services have been discussed as potential new bioinformatics support systems but have not been evaluated thoroughly...
CloVR: a virtual machine for automated and portable sequence analysis from the desktop using cloud computingSamuel V Angiuoli
Institute for Genome Sciences IGS, University of Maryland School of Medicine, Baltimore, Maryland, USA
BMC Bioinformatics 12:356. 2011..Cloud computing platforms provide on-demand access to computing infrastructure over the Internet and can be used in combination with custom built virtual machines to distribute pre-packaged with pre-configured software...
A comparative genomic analysis of diverse clonal types of enterotoxigenic Escherichia coli reveals pathovar-specific conservationJason W Sahl
University of Maryland School of Medicine, Institute for Genome Sciences, Baltimore, MD, USA
Infect Immun 79:950-60. 2011..These studies increase our understanding of ETEC evolution, as well as provide insight into virulence factors and conserved proteins, which may be targets for vaccine development...
Using Sybil for interactive comparative genomics of microbes on the webDavid R Riley
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
Bioinformatics 28:160-6. 2012..In addition to scalability, comparative genomics tools must also provide user-friendly interfaces such that the research scientist can explore complex data with minimal technical expertise...
Ergatis: a web interface and scalable software system for bioinformatics workflowsJoshua Orvis
Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
Bioinformatics 26:1488-92. 2010..Software is also needed to simplify data management and make large-scale bioinformatics analysis accessible and reproducible to a wide class of target users...
Comparative genomics of the neglected human malaria parasite Plasmodium vivaxJane M Carlton
The Institute for Genomic Research J Craig Venter Institute, 9704 Medical Research Drive, Rockville, Maryland 20850, USA
Nature 455:757-63. 2008..Completion of the P. vivax genome provides the scientific community with a valuable resource that can be used to advance investigation into this neglected species...
Sybil: methods and software for multiple genome comparison and visualizationJonathan Crabtree
Institute for Genomic Research, Rockville, MD, USA
Methods Mol Biol 408:93-108. 2007....
Comparative genomics of emerging human ehrlichiosis agentsJulie C Dunning Hotopp
The Institute for Genomic Research, Rockville, Maryland, USA
PLoS Genet 2:e21. 2006..These discoveries provide significant insights into the biology of these obligate intracellular pathogens...
Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this speciesKaren E Nelson
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Nucleic Acids Res 32:2386-95. 2004..Whole genome comparative analyses revealed that the L.monocytogenes genomes are essentially syntenic, with the majority of genomic differences consisting of phage insertions, transposable elements and SNPs...
