Jeffrey D Alexis

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model
    Jeffrey D Alexis
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14586, USA
    J Vasc Res 45:538-46. 2008
  2. ncbi Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells
    Jeffrey D Alexis
    Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circ Res 104:69-78. 2009
  3. ncbi UAP56 is an important regulator of protein synthesis and growth in cardiomyocytes
    Abha Sahni
    Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, Rochester, NY 14642, USA
    Biochem Biophys Res Commun 393:106-10. 2010
  4. ncbi Immunologic factors in transplant arteriopathy: insight from animal models
    Jeffrey D Alexis
    Department of Medicine, Box 1030, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mt Sinai J Med 70:191-6. 2003
  5. ncbi Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice
    Patrizia Nigro
    Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Exp Med 208:53-66. 2011

Research Grants

  1. Bcr and PPARgamma as targets for transplant arteriopathy
    JEFFREY ALEXIS; Fiscal Year: 2007

Collaborators

Detail Information

Publications5

  1. ncbi Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model
    Jeffrey D Alexis
    Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14586, USA
    J Vasc Res 45:538-46. 2008
    ..Using knockout mice, we have now examined the role of MCP-1 and CCR2 in the development of the intimal proliferation of transplant arteriopathy...
  2. ncbi Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells
    Jeffrey D Alexis
    Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circ Res 104:69-78. 2009
    ....
  3. ncbi UAP56 is an important regulator of protein synthesis and growth in cardiomyocytes
    Abha Sahni
    Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, Rochester, NY 14642, USA
    Biochem Biophys Res Commun 393:106-10. 2010
    ..Our data demonstrate that UAP56 is an important regulator of protein synthesis and plays an important role in the regulation of cardiomyocyte growth...
  4. ncbi Immunologic factors in transplant arteriopathy: insight from animal models
    Jeffrey D Alexis
    Department of Medicine, Box 1030, Mount Sinai School of Medicine, New York, NY 10029, USA
    Mt Sinai J Med 70:191-6. 2003
    ..One goal of future studies will be to translate findings in animal models into effective treatments in humans...
  5. ncbi Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice
    Patrizia Nigro
    Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Exp Med 208:53-66. 2011
    ..These data define a role for CyPA in atherosclerosis and suggest CyPA as a target for cardiovascular therapies...

Research Grants2

  1. Bcr and PPARgamma as targets for transplant arteriopathy
    JEFFREY ALEXIS; Fiscal Year: 2007
    ..These approaches to discovering the pathogenesis of cardiovascular disease will be critical to understanding and developing new therapies for transplant arteriopathy. ..