Research Topics
| G C AlexanderSummaryAffiliation: University of Chicago Country: USA Publications
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Publications
Characteristics of patients receiving pharmaceutical samples and association between sample receipt and out-of-pocket prescription costsG Caleb Alexander
Section of General Internal Medicine, Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
Med Care 46:394-402. 2008..Pharmaceutical samples are widely used for promotion and marketing, yet little is known about who receives samples or how their use is associated with patient's prescription costs...
Physician strategies to reduce patients' out-of-pocket prescription costsG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, MacLean Center for Medical Ethics, The University of Chicago, Chicago, IL 60637, USA
Arch Intern Med 165:633-6. 2005..Physicians often do not communicate with patients about out-of-pocket costs, although research indicates that physicians and patients value such discussion...
Consumers' perceptions about risk of and access to nonprescription medicationsG Caleb Alexander
Clinical Scholars Program, University of Chicago, 5841 S Maryland, MC 2007, Chicago, IL 60637, USA
J Am Pharm Assoc (2003) 45:363-70. 2005....
Barriers to patient-physician communication about out-of-pocket costsG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, University of Chicago, IL 60637, USA
J Gen Intern Med 19:856-60. 2004..Though many patients and physicians believe that they should discuss out-of-pocket costs, research suggests that they infrequently do...
Six strategies to identify and assist patients burdened by out-of-pocket prescription costsG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, IL 60637, USA
Cleve Clin J Med 71:433-7. 2004..Many patients find that their out-of-pocket costs of medications are burdensome. Physicians can help, first by remembering to ask about the problem, and then by applying simple strategies to limit the patient's costs...
Enhancing prescription drug innovation and adoptionG Caleb Alexander
University of Chicago Hospitals, University of Chicago, University of Chicago Medical Center, Chicago, Illinois 60637, USA
Ann Intern Med 154:833-7, W-301. 2011..Despite the challenges of policy implementation, the United States has a long history of successfully improving the societal value and safe use of prescription medicines...
The costs of denying scarcityG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, University of Chicago, 5841 S Maryland, MC 2007, Chicago, IL 60637, USA
Arch Intern Med 164:593-6. 2004
Physicians in retainer ("concierge") practice. A national survey of physician, patient, and practice characteristicsG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, The University of Chicago, Chicago, IL 60637, USA
J Gen Intern Med 20:1079-83. 2005..Retainer practices represent a new model of care whereby physicians charge an up-front fee for services that may not be covered by health insurance. The characteristics of these practices are largely unknown...
Commentary on "The Case of Mr. A.B.": dilemmas for a reasonG Caleb Alexander
General Internal Medicine, Center for Advanced Medicine, University of Chicago Medical Center, USA
J Clin Ethics 19:70-1. 2008
Physicians' preparedness for bioterrorism and other public health prioritiesG Caleb Alexander
MacLean Center for Clinical Medical Ethics, and Division of General Internal Medicine, University of Chicago, 5841 South Maryland Avenue, MC 2007, Chicago, IL 60637, USA
Acad Emerg Med 13:1238-41. 2006..Earlier surveys showed low physician bioterrorism preparedness but did not assess physicians' general public health preparedness, compare the preparedness of emergency and primary care physicians, or assess temporal trends...
Increasing off-label use of antipsychotic medications in the United States, 1995-2008G C Alexander
Department of Medicine, University of Chicago Hospitals, Chicago, Illinois, USA
Pharmacoepidemiol Drug Saf 20:177-84. 2011..We also quantified use without U.S. Food and Drug Administration approval (off-label use) and off-label use with compendium data suggesting an uncertain evidence base...
National trends in treatment of type 2 diabetes mellitus, 1994-2007G Caleb Alexander
Department of Medicine, Section of General Internal Medicine, The University of Chicago, Chicago, IL 60637, USA
Arch Intern Med 168:2088-94. 2008..Diabetes mellitus is common, costly, and increasingly prevalent. Despite innovations in therapy, little is known about patterns and costs of drug treatment...
Neighborhood poverty, racial composition and renal transplant waitlistM R Saunders
Department of Medicine, University of Chicago Medical Center, Chicago, IL, USA
Am J Transplant 10:1912-7. 2010..05). Interventions targeted at individuals in poor and minority neighborhoods may represent an opportunity to improve equitable access to the deceased donor kidney waitlist...
Outpatient hypertension treatment, treatment intensification, and control in Western Europe and the United StatesY Richard Wang
Department of Medicine, Temple University Hospital, Philadelpia, PA 19140, USA
Arch Intern Med 167:141-7. 2007..Hypertension guidelines in the United States tend to have more aggressive treatment recommendations than those in European countries...
Out-of-pocket and total costs of fixed-dose combination antihypertensives and their componentsAtonu Rabbani
Center for Health and Social Sciences, University of Chicago, Chicago, Illinois, USA
Am J Hypertens 21:509-13. 2008..Many patients are burdened by prescription costs, yet it is not clear whether brand-named fixed-dose combination medicines are less expensive than the sum of the cost of their generic components...
National prevalence of lifestyle counseling or referral among African-Americans and whites with diabetesMonica E Peek
Section of General Internal Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA
J Gen Intern Med 23:1858-64. 2008..Despite this, little is known about how frequently physicians provide counseling or referral to address these risk factors, or whether such rates differ by patient race...
The physician-surrogate relationshipAlexia M Torke
MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, Ill 60637, USA
Arch Intern Med 167:1117-21. 2007..We outline key issues affecting the physician-surrogate relationship and provide guidance for physicians who are making decisions with surrogates...
Use of prescription and over-the-counter medications and dietary supplements among older adults in the United StatesDima M Qato
Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA
JAMA 300:2867-78. 2008..Despite concerns about drug safety, current information on older adults' use of prescription and over-the-counter medications and dietary supplements is limited...
General internists' views on pay-for-performance and public reporting of quality scores: a national surveyLawrence P Casalino
Department of Health Studies, University of Chicago, IL, USA
Health Aff (Millwood) 26:492-9. 2007..Public and private policymakers might avoid a physician backlash and better succeed at improving health care quality if they consider these concerns when designing P4P and public reporting programs...
The association between family structure, reports of illness and health care demand for children: evidence from rural BangladeshAtonu Rabbani
Center for Health and Social Sciences, University of Chicago, Chicago, IL, USA
J Biosoc Sci 41:645-59. 2009..13; CI 1.01-1.27), though not for girls (OR 0.96; CI 0.84-1.09). Overall, the likelihood of a doctor's visit for a sick child was positively related to household income and at the highest levels of income was a virtual certainty...
Reconsidering medication appropriateness for patients late in lifeHolly M Holmes
Arch Intern Med 166:605-9. 2006
Variation in access to kidney transplantation across dialysis facilities: using process of care measures for quality improvementG Caleb Alexander
Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Am J Kidney Dis 40:824-31. 2002..Examining specific steps in the transplantation process may guide quality improvement efforts that ultimately improve the equity and efficiency of transplantation...
Impact of Medicare Part D on Medicare-Medicaid dual-eligible beneficiaries' prescription utilization and expendituresAnirban Basu
Section of General Internal Medicine, Department of Medicine, and Center for Health and the Social Sciences, University of Chicago, IL, USA
Health Serv Res 45:133-51. 2010..To examine the effect of Part D on 65-78-year-old noninstitutionalized dual eligibles' prescription utilization and expenditures...
Support for physician deception of insurance companies among a sample of Philadelphia residentsG Caleb Alexander
University of Pennsylvania, Philadelphia, USA
Ann Intern Med 138:472-5. 2003..Some physicians seem to be willing to sanction deception of insurance companies. Little is known about public attitudes regarding this practice...
Patient-physician communication about out-of-pocket costsG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, University of Chicago, Chicago, Ill 60637, USA
JAMA 290:953-8. 2003..Previous research suggests that these costs are associated with medication nonadherence and considerable economic burden among some patients. Little is known about patient-physician communication regarding these costs...
Racial and ethnic disparities in cardiovascular medication use among older adults in the United StatesDima M Qato
Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA
Pharmacoepidemiol Drug Saf 19:834-42. 2010..We examined racial and ethnic disparities in the use of statins and aspirin among older adults at low, moderate, and high risk for CVD...
Ready and willing? Physicians' sense of preparedness for bioterrorismG Caleb Alexander
Division of General Internal Medicine, MacLean Center for Medical Ethics, University of Chicago Hospitals, USA
Health Aff (Millwood) 22:189-97. 2003..Preparing physicians for bioterrorism should entail providing practical knowledge, preventive steps to minimize risk, and reinforcement of the profession's ethical duty to treat...
A qualitative study of physicians' engagement in reducing healthcare disparitiesSusanne K Vanderbilt
Pritzker School of Medicine, University of Chicago, IL 60637, USA
J Natl Med Assoc 99:1315-22. 2007....
A comparison of patient and physician beliefs about infrainguinal bypass operation: what role should surgical optimism play?Margaret L Schwarze
Department of Surgery, MacLean Center for Clinical Medical Ethics, University of Chicago, IL, USA
Surgery 141:239-44. 2007..Little is known about whether patients and physicians have similar beliefs regarding the risks and benefits of the operation...
National trends in cyclooxygenase-2 inhibitor use since market release: nonselective diffusion of a selectively cost-effective innovationCarolanne Dai
Harris School of Public Policy Studies, The University of Chicago, IL 60637, USA
Arch Intern Med 165:171-7. 2005..These findings demonstrate the challenge of limiting innovative therapies to the settings in which they are initially targeted and maximally beneficial...
Prioritizing future research on off-label prescribing: results of a quantitative evaluationSurrey M Walton
Chicago Area Developing Evidence to Inform Decisions about Effectiveness DEcIDE Center, Chicago, IL 60612, USA
Pharmacotherapy 28:1443-52. 2008..To develop a prioritized list of individual drugs for which future research regarding off-label uses is warranted...
Why hemodialysis patients fail to complete the transplantation processG C Alexander
Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Am J Kidney Dis 37:321-8. 2001..The relative importance of these types of movement differs among blacks and whites...
Changes in glitazone use among office-based physicians in the U.S., 2003-2009Andrew Cohen
Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA
Diabetes Care 33:823-5. 2010..Little is known regarding recent changes in glitazone use...
Impact of family structure on stimulant use among children with attention-deficit/hyperactivity disorderAtonu Rabbani
Center for Health and Social Sciences, The University of Chicago, 5841 S Maryland, Chicago, IL, USA
Health Serv Res 44:2060-78. 2009..To examine the impact of family structure on pharmacologic stimulant use among children with attention-deficit/hyperactivity disorder (ADHD)...
Development of a measure of physician engagement in addressing racial and ethnic health care disparitiesG Caleb Alexander
The University of Chicago, 5841 S Maryland, MC 2007, Chicago, IL 60637, USA
Health Serv Res 43:773-84. 2008..To develop a measure of physician engagement in addressing health care disparities...
Prioritizing and stopping prescription medicinesG Caleb Alexander
Robert Wood Johnson Clinical Scholars Program, MacLean Center for Clinical Medical Ethics, Section of General Internal Medicine, Department of Medicine, University of Chicago, Chicago, Ill, USA
CMAJ 174:1083-4. 2006
Cost savings associated with filling a 3-month supply of prescription medicinesAtonu Rabbani
Center for Health and Social Sciences, University of Chicago, Chicago, Illinois, USA
Appl Health Econ Health Policy 7:255-64. 2009..Many patients are burdened by prescription costs, and patients, providers and policy makers may attempt to reduce these costs by substituting 3-month for 1-month supplies of medicines...
Rethinking professional ethics in the cost-sharing eraG Caleb Alexander
University of Chicago, Chicago, Illinois, USA
Am J Bioeth 6:W17-22. 2006....
Design and evaluation of a workplace intervention to promote organ donationMichael T Quinn
University of Chicago, Chicago, Illinois, USA
Prog Transplant 16:253-9. 2006..001). CONCLUSIONS: Educational interventions in the corporate workplace setting can be effective in increasing organ donation intention, family notification, and recruitment of family members as potential organ donors...
Prescriptions of sleepG Caleb Alexander
Department of Medicine, MacLean Center for Medical Ethics, University of Chicago, Illinois, USA
Can Fam Physician 50:543, 545. 2004
Knowledge and early adoption of the HPV vaccine among girls and young women: results of a national surveyRachel Caskey
Sections of General Internal Medicine and Pediatrics, University of Illinois at Chicago, Chicago, Illinois 60612, USA
J Adolesc Health 45:453-62. 2009..In 2006, universal human papillomavirus (HPV) vaccination of females ages 9 to 26 years became a formal recommendation, yet little is known about knowledge and adoption of this vaccine...
A qualitative exploration of depression in emerging adulthood: disorder, development, and social contextSachiko A Kuwabara
University of Chicago, Chicago, IL 60637, USA
Gen Hosp Psychiatry 29:317-24. 2007..One in four emerging adults will experience a depressive episode between the ages of 18-25. We examined the lived experience of emerging adults with a focus on their treatment seeking, development and the social context of their illness...
The doctor-patient relationship in the post-managed care eraG Caleb Alexander
The University of Chicago, USA
Am J Bioeth 6:29-32. 2006....
Academic medical centers and underserved communities: modern complexities of an enduring relationshipAllison Lale
Pritzker School of Medicine, The University of Chicago, IL 60637, USA
J Natl Med Assoc 102:605-13. 2010..Most private academic medical centers are located in underserved areas, yet fiscal pressures have led many to struggle with balancing their commitment to surrounding communities with other missions...
Exploring patient preferences for infrainguinal bypass operationMargaret L Schwarze
Department of Surgery, University of Chicago Hospitals, Chicago, IL, USA
J Am Coll Surg 202:445-52. 2006..Surgical risk and outcomes for patients undergoing infrainguinal bypass operation vary by identifiable patient characteristics, yet little is known about whether patients understand the risks, benefits, and alternatives to operation...
Lying to insurance companies: the desire to deceive among physicians and the publicRachel M Werner
University of Pennsylvania, USA
Am J Bioeth 4:53-9. 2004..48 to 4.64 after controlling for differences in time perception. These findings highlight the ethical challenge facing physicians and patients in balancing patient advocacy with honesty in the setting of limited societal resources...
The "Hassle Factor": what motivates physicians to manipulate reimbursement rules?Rachel M Werner
Department of Internal Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Arch Intern Med 162:1134-9. 2002..This study sought to determine the relationship between the likelihood of a successful appeal, appeals process length, and severity of the health condition and physicians' willingness to sanction deception...
Rethinking the ethical framework for surrogate decision making: a qualitative study of physiciansAlexia M Torke
Indiana University Center for Aging Research, Regenstrief Institute, USA
J Clin Ethics 19:110-9. 2008
Elderly patients' preferences and experiences with providers in managing their drug costsChien Wen Tseng
Department of Family Medicine and Community Health, University of Hawaii, Honolulu, Hawaii, USA
J Am Geriatr Soc 55:1974-80. 2007..To determine whether elderly patients with high drug expenditures want and receive providers' help in managing drug costs...
Shoring up professionalism. Building on disagreements between residents and attending physiciansG Caleb Alexander
Can Fam Physician 52:286-8, 294-6. 2006
Screening and treatment of hypercholesterolemia for prevention of coronary heart diseaseY Richard Wang
Public Policy Department, AstraZeneca Pharmaceuticals, Wilmington, Delaware 19850, USA
Manag Care Interface 19:25-9. 2006..Drug therapy recommendation also decreasedwith greater NCEP risk. Despite improvements, underscreening and undertreatment of hypercholesterolemia persists in outpatient visits...
A practical physicians' guide to the Medicare drug benefit planAlex D Federman
Division of General Internal Medicine, Mount Sinai School of Medicine, Mount Sinai Hospital, New York, New York 10029, USA
Mayo Clin Proc 81:1217-21. 2006..This may, in turn, reduce beneficiaries' out-of-pocket prescription costs, thereby improving patients' access to medications and possibly their medication adherence and health outcomes as well...
Physician consideration of patients' out-of-pocket costs in making common clinical decisionsHoangmai H Pham
Center for Studying Health System Change, 600 Maryland Avenue SW, Washington, DC 20024, USA
Arch Intern Med 167:663-8. 2007..Patients face growing cost-sharing through higher deductibles and other out-of-pocket (OP) expenses, with uncertain effects on clinical decision making...
Assessing competence of residents to discuss end-of-life issuesMary Kathleen Buss
Divisions of Pain and Palliative Care and Thoracic Oncology, Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA
J Palliat Med 8:363-71. 2005..Residents are often responsible for eliciting patients' treatment preferences at the end of life (EOL), yet we have a limited understanding of their competence in this task...
The effect of the Medicare Part D prescription benefit on drug utilization and expendituresWesley Yin
Robert Wood Johnson Scholars in Health Policy Program, Harvard University, Cambridge, Massachusetts, USA
Ann Intern Med 148:169-77. 2008..Information about the effect of the Medicare Part D Prescription Drug Benefit on drug utilization and expenditures is limited...
The nuances of self-disclosureG Caleb Alexander
Arch Intern Med 168:242-3; author reply 243-4. 2008
