Research Topics
| Erick H TurnerSummaryCountry: USA Publications
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Detail Information
Publications
Double-blind, placebo-controlled study of single-dose metergoline in depressed patients with seasonal affective disorderErick H Turner
Section on Biological Rhythms, Intramural Research Program, National Institute of Mental Health, Bethesda, Maryland, USA
J Clin Psychopharmacol 22:216-20. 2002..These data suggest that single doses of metergoline may have antidepressant effects that last several days. Possible mechanisms include 5-hydroxytryptamine(2) receptor downregulation and dopamine agonism...
Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophanErick H Turner
Mood Disorders Center, Portland VA Medical Center, Portland, OR 97239, USA
Pharmacol Ther 109:325-38. 2006..Safety issues with 5-HTP are also reviewed, with emphasis on eosinophilia myalgia syndrome (EMS) and serotonin syndrome...
5-Hydroxytryptophan plus SSRIs for interferon-induced depression: synergistic mechanisms for normalizing synaptic serotoninErick H Turner
Mental Health Division, Mood Disorders Research Center, Portland VA Medical Center, 3710 SW US Veterans Hospital Rd, Portland, OR 97239, USA
Med Hypotheses 65:138-44. 2005..Several double-blind studies have shown 5-HTP to be effective in the treatment of nondrug-induced depression. We hypothesize that patients who become depressed on IFN will respond to the synergistic combination of SSRIs plus 5-HTP...
Patients with seasonal affective disorder have lower odor detection thresholds than control subjectsTeodor T Postolache
Section on Biological Rhythms, National Institute of Mental Health NIH, 10 Center Dr, Room 3S 231, Bethesda, MD 20892, USA
Arch Gen Psychiatry 59:1119-22. 2002..Because the olfactory system has a modulatory role in seasonal photoperiodic responses in certain species, we hypothesized that olfactory function may differ between patients with seasonal affective disorder and healthy control subjects...
Selective publication of antidepressant trials and its influence on apparent efficacyErick H Turner
Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA
N Engl J Med 358:252-60. 2008..Selective publication of clinical trials--and the outcomes within those trials--can lead to unrealistic estimates of drug effectiveness and alter the apparent risk-benefit ratio...
Strategies to decrease costs of prescribing selective serotonin reuptake inhibitors at a VA Medical CenterSteven K Dobscha
Portland Veterans Affairs Medical Center, Oregon 97207, USA
Psychiatr Serv 54:195-200. 2003..The authors examined the efficacy of a multifaceted intervention designed to contain the cost of prescribing selective serotonin reuptake inhibitors (SSRIs) to inpatients and outpatients served by a Veterans Affairs (VA) medical center...
Is it always unethical to use a placebo in a clinical trial?Andreas Stang
Institute of Medical Epidemiology, Biometry, and Informatics at the Medical Faculty of the Martin Luther University of Halle Wittenberg, Germany
PLoS Med 2:e72. 2005..Critics of such trials argue that if a proven effective therapy exists, a placebo should not be used. But proponents argue that placebo trials are still crucial to prove the efficacy and safety of many treatments...
Efficacy of antidepressantsErick H Turner
BMJ 336:516-7. 2008
