Research Topics
Species | Paul WheltonSummaryAffiliation: Tulane University Country: USA Publications
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Publications
Sodium reduction and weight loss in the treatment of hypertension in older persons: a randomized controlled trial of nonpharmacologic interventions in the elderly (TONE). TONE Collaborative Research GroupP K Whelton
Department of Biostatistics and Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
JAMA 279:839-46. 1998..Nonpharmacologic interventions are frequently recommended for treatment of hypertension in the elderly, but there is a paucity of evidence from randomized controlled trials in support of this recommendation...- Potassium in preventing and treating high blood pressureP K Whelton
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Semin Nephrol 19:494-9. 1999..Increased potassium intake should be included as a recommendation for prevention and treatment of hypertension, especially in those who are unable to reduce their intake of sodium... - Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Paul K Whelton
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Arch Intern Med 165:1401-9. 2005.... - Prevalence, awareness, treatment and control of hypertension in North America, North Africa and AsiaP K Whelton
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
J Hum Hypertens 18:545-51. 2004..These survey results underscore the fact that hypertension is highly prevalent, poorly treated and controlled, and an escalating health challenge in economically developing countries... - Hypertension curriculum review: epidemiology and the prevention of hypertensionPaul K Whelton
Tulane University Health Sciences Center, New Orleans, LA 70112, USA
J Clin Hypertens (Greenwich) 6:636-42. 2004 - Association of symptoms of depression and obesity with hypertension: the Bogalusa Heart StudyAzad Alamgir Kabir
Center for Cardiovascular Health, Tulane University Health Sciences Center, 1440 Canal Street, New Orleans, LA 70112, USA
Am J Hypertens 19:639-45. 2006..The objective of this study was to evaluate the direct and indirect relationships between symptoms of depression, body mass index (BMI), and hypertension in a biracial (African American-white) rural population... - Serum antioxidant vitamins and blood pressure in the United States populationJing Chen
Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA
Hypertension 40:810-6. 2002..These findings indicate that antioxidant vitamins may be important in the underlying cause and prevention of hypertension. Further studies in this important area are warranted... - Dietary intake of folate and risk of stroke in US men and women: NHANES I Epidemiologic Follow-up Study. National Health and Nutrition Examination SurveyLydia A Bazzano
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Stroke 33:1183-8. 2002..Increasing dietary intake of folate from food sources may be an important approach to the prevention of CVD in the US population... - Geographic variations in the prevalence, awareness, treatment and control of hypertension in ChinaKristi Reynolds
Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
J Hypertens 21:1273-81. 2003..The previously reported urban-rural difference in the prevalence of hypertension was not noted, perhaps due to a rapid increase in the prevalence of hypertension in rural China... - The metabolic syndrome and chronic kidney disease in U.S. adultsJing Chen
Tulane University Schools of Medicine and Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
Ann Intern Med 140:167-74. 2004..62 (CI, 1.10 to 2.38), 2.45 (CI, 1.55 to 3.85), and 3.19 (CI, 1.96 to 5.19), respectively. CONCLUSIONS: These findings suggest that the metabolic syndrome might be an important factor in the cause of chronic kidney disease... - Hypertension subtype and risk of cardiovascular disease in Chinese adultsTanika N Kelly
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Circulation 118:1558-66. 2008..We examined the relationship between hypertension subtype and cardiovascular disease incidence and mortality in Chinese adults... - Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education ProgramPaul K Whelton
Department of Epidemiology and Medicine, Tulane University Health Sciences Center, Tulane University, New Orleans, LA, USA
JAMA 288:1882-8. 2002.... - Relationship of serum antioxidant vitamins to serum creatinine in the US populationJing Chen
Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA
Am J Kidney Dis 39:460-8. 2002..Our study provides useful information to support the hypothesis that antioxidant vitamins may have an important role in the pathogenesis of chronic renal failure... - Metabolic syndrome and salt sensitivity of blood pressure in non-diabetic people in China: a dietary intervention studyJing Chen
Department of Medicine and Tulane Hypertension and Renal Center of Excellence, School of Medicine, Tulane University, New Orleans, LA, USA
Lancet 373:829-35. 2009..We aimed to examine the association between metabolic syndrome and salt sensitivity of blood pressure... - Relationship between cigarette smoking and novel risk factors for cardiovascular disease in the United StatesLydia A Bazzano
Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
Ann Intern Med 138:891-7. 2003..CONCLUSIONS: These findings suggest that inflammation and hyperhomocysteinemia may be important mechanisms by which smoking promotes atherosclerotic disease... - A population-based, prospective study of blood pressure and risk for end-stage renal disease in ChinaKristi Reynolds
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, New Orleans, LA 70112, USA
J Am Soc Nephrol 18:1928-35. 2007..These results document the importance of high BP as a modifiable risk factor for ESRD in China. Strategies to prevent ESRD should incorporate the prevention, treatment, and control of BP... - Association between inflammation and insulin resistance in U.S. nondiabetic adults: results from the Third National Health and Nutrition Examination SurveyJing Chen
Department of Medicine, Tulane University School of Medicine, 1430 Tulane Ave, SL45, New Orleans, LA 70112, USA
Diabetes Care 27:2960-5. 2004..These findings indicate that elevated levels of inflammatory markers are positively and independently associated with insulin resistance. Further studies should examine the potential causal effect of inflammation on insulin resistance... - Serum total and lipoprotein cholesterol levels and awareness, treatment, and control of hypercholesterolemia in ChinaJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Ave SL18, New Orleans, LA 70112, USA
Circulation 110:405-11. 2004..Cardiovascular disease has become the leading cause of death in China. We examined the levels of serum total and lipoprotein cholesterol and status of awareness, treatment, and control of hypercholesterolemia in China... - Prevalence of non-traditional cardiovascular disease risk factors among persons with impaired fasting glucose, impaired glucose tolerance, diabetes, and the metabolic syndrome: analysis of the Third National Health and Nutrition Examination Survey (NHANESPaul Muntner
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
Ann Epidemiol 14:686-95. 2004..To calculate the prevalence of non-traditional cardiovascular disease (CVD) risk factors across diabetes status and for persons with and without the metabolic syndrome... - Cigarette smoking and erectile dysfunction among Chinese men without clinical vascular diseaseJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Am J Epidemiol 166:803-9. 2007..8 million cases) among Chinese men are attributable to cigarette smoking. This 2000-2001 study of Chinese men documented an independent and dose-response relation between cigarette smoking and risk of erectile dysfunction... - Cigarette smoking and exposure to environmental tobacco smoke in China: the international collaborative study of cardiovascular disease in AsiaDongfeng Gu
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Avenue SL18, New Orleans, LA 70112, USA
Am J Public Health 94:1972-6. 2004..We estimated the prevalence of cigarette smoking and the extent of environmental tobacco smoke exposure (ETS) in the general population in China... - Association between the metabolic syndrome and chronic kidney disease in Chinese adultsJing Chen
Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, SL 45, New Orleans, LA 70112, USA, and the Cardiovascular Institute and Fuwai Hospital, Beijing, China
Nephrol Dial Transplant 22:1100-6. 2007..The metabolic syndrome is a common risk factor for cardiovascular and chronic kidney disease (CKD) in Western populations. We examined the relationship between the metabolic syndrome and risk of CKD in Chinese adults... - Prevalence and risk factors of overweight and obesity in ChinaKristi Reynolds
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Avenue SL 18, New Orleans, LA 70112, USA
Obesity (Silver Spring) 15:10-8. 2007..To examine the prevalence and risk factors of overweight and obesity in China... - Trends in the prevalence, awareness, treatment, and control of cardiovascular disease risk factors among noninstitutionalized patients with a history of myocardial infarction and strokePaul Muntner
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Am J Epidemiol 163:913-20. 2006..20). The number of US myocardial infarction and stroke survivors increased between 1988-1994 and 1999-2002, and substantial improvements occurred in the awareness, treatment, and control of high LDL cholesterol in this population... - Prevalence of decreased kidney function in Chinese adults aged 35 to 74 yearsJing Chen
Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA
Kidney Int 68:2837-45. 2005..Chronic kidney disease (CKD) is a major public health burden in Western countries but little is known about its impact in developing countries. We estimated the prevalence and absolute burden of CKD in the general adult population in China... - Therapeutic lifestyle changes and drug treatment for high blood cholesterol in China and application of the Adult Treatment Panel III guidelinesPaul Muntner
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
Am J Cardiol 96:1260-5. 2005..3 million (4.1% of adults). In conclusion, most adults in China with an elevated LDL cholesterol remain untreated... - Major causes of death among men and women in ChinaJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
N Engl J Med 353:1124-34. 2005..We studied the major causes of death and modifiable risk factors in a nationally representative cohort of 169,871 men and women 40 years of age and older in China... - Prevalence of physical activity among Chinese adults: results from the International Collaborative Study of Cardiovascular Disease in AsiaPaul Muntner
Department of Epidemiology, Tulane University SPHTM, 1430 Tulane Ave, SL 18, New Orleans, LA 70112, USA
Am J Public Health 95:1631-6. 2005..Therefore, we assessed overall, work-related, and leisure-time physical activity in a representative sample of Chinese adults, aged 35 to 74 years, using data from the International Collaborative Study of Cardiovascular Disease in Asia... - Effect of soybean protein on blood pressure: a randomized, controlled trialJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Avenue, SL 18, New Orleans, LA 70112 2699, USA
Ann Intern Med 143:1-9. 2005..Epidemiologic studies suggest that vegetable protein intake is inversely related to blood pressure... - Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt studyQi Zhao
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA
Am J Hypertens 23:606-13. 2010..We examined the association of genetic variants in the apelin-APJ system and angiotensin-converting enzyme 2 (ACE2) with BP responses to potassium supplementation... - Prevalence of the metabolic syndrome and overweight among adults in ChinaDongfeng Gu
Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Lancet 365:1398-405. 2005..Little information exists on the prevalence of the metabolic syndrome in China. We aimed to provide up-to-date estimates of the prevalence of the metabolic syndrome and overweight in the general adult population in China... - International collaborative study of cardiovascular disease in Asia: design, rationale, and preliminary resultsJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Avenue SL 18, New Orleans, LA 70112 2073, USA
Ethn Dis 14:260-8. 2004.... - Trends in blood pressure among children and adolescentsPaul Muntner
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
JAMA 291:2107-13. 2004..The prevalence of overweight among children and adolescents increased between 1988 and 2000. The change in blood pressure among children and adolescents over that time and the role of overweight is unknown... - Insulin resistance and risk of chronic kidney disease in nondiabetic US adultsJing Chen
Tulane University School of Medicine, New Orleans, Louisiana, USA
J Am Soc Nephrol 14:469-77. 2003..Further studies into the causality between insulin resistance and CKD are warranted... - Gender difference in blood pressure responses to dietary sodium intervention in the GenSalt studyJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
J Hypertens 27:48-54. 2009..To examine factors related to blood pressure (BP) responses to dietary sodium and potassium interventions... - History of myocardial infarction and stroke among incident end-stage renal disease cases and population-based controls: an analysis of shared risk factorsPaul Muntner
Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
Am J Kidney Dis 40:323-30. 2002..A history of myocardial infarction (MI) and stroke is more common among incident cases of treated end-stage renal disease (ESRD) than in the general US population... - Dietary sodium intake and incidence of congestive heart failure in overweight US men and women: first National Health and Nutrition Examination Survey Epidemiologic Follow-up StudyJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Ave, Mail Box SL18, New Orleans, LA 70112, USA
Arch Intern Med 162:1619-24. 2002..We studied the relationship between dietary sodium intake and incidence of congestive heart failure (CHF) in the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study participants... - Factors associated with hypertension control in the general population of the United StatesJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1430 Tulane Ave SL18, New Orleans, LA 70112, USA
Arch Intern Med 162:1051-8. 2002..Uncontrolled hypertension is the most common and important risk factor for cardiovascular and renal disease. We studied factors associated with hypertension control in the Third National Health and Nutrition Examination Survey... - Salt intake, hypertension and risk of cardiovascular disease: an important public health challengeJiang He
Tulane University, School of Public Health and Tropical Medicine and School of Medicine, New Orleans, LA 70112, USA
Int J Epidemiol 31:327-31; discussion 331-2. 2002 - The impact of JNC-VI guidelines on treatment recommendations in the US populationPaul Muntner
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Hypertension 39:897-902. 2002..We conclude that JNC-VI refines cardiovascular risk and enfranchises more Americans to undertake more aggressive risk reduction maneuvers... - Renal insufficiency and subsequent death resulting from cardiovascular disease in the United StatesPaul Muntner
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana 70112, USA
J Am Soc Nephrol 13:745-53. 2002..This study indicates that, in a representative sample of the United States general population, renal insufficiency is independently associated with increased cardiovascular disease-related and all-cause mortality rates... - Premature deaths attributable to blood pressure in China: a prospective cohort studyJiang He
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
Lancet 374:1765-72. 2009..Hypertension is a major global-health challenge because of its high prevalence and concomitant risks of cardiovascular disease. We estimated premature deaths attributable to increased blood pressure in China... - Surviving Hurricane Katrina: reconstructing the educational enterprise of Tulane University School of MedicineN Kevin Krane
University Health Sciences Center, New Orleans, Louisiana 70012, USA
Acad Med 82:757-62. 2007.... - Effect of dietary fiber intake on blood pressure: a randomized, double-blind, placebo-controlled trialJiang He
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
J Hypertens 22:73-80. 2004..To examine the effect of dietary fiber intake on blood pressure (BP)... - Worldwide prevalence of hypertension: a systematic reviewPatricia M Kearney
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
J Hypertens 22:11-9. 2004..To examine the prevalence and the level of awareness, treatment and control of hypertension in different world regions... - Primary prevention of essential hypertensionMarie A Krousel-Wood
Clinical Outcomes Research, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA
Med Clin North Am 88:223-38. 2004.... - Association between blood pressure responses to the cold pressor test and dietary sodium intervention in a Chinese populationJing Chen
Department of Medicine, Tulane University School of Medicine, 1443 Tulane Ave SL45, New Orleans, LA 70112, USA
Arch Intern Med 168:1740-6. 2008..We examined the association between BP responses to the CPT and to dietary sodium and potassium interventions... - Factors associated with hypertension awareness, treatment, and control in a representative sample of the chinese populationPaul Muntner
Department of Epidemiology, Tulane University, SPHTM 1430 Tulane Avenue, SL 18 New Orleans, LA 70112, USA
Hypertension 43:578-85. 2004..59; 1.11, 2.27). These data identify potential methods for improving blood pressure control in China through the identification, follow-up, and lifestyle modification of persons with high blood pressure... - The prevalence of nontraditional risk factors for coronary heart disease in patients with chronic kidney diseasePaul Muntner
Tulane University, New Orleans, Louisiana, USA
Ann Intern Med 140:9-17. 2004..6), and 1.93 (CI, 1.33 to 2.81), respectively. CONCLUSIONS: Levels of apolipoprotein A1 are decreased and levels of homocysteine, lipoprotein(a), fibrinogen, and C-reactive protein are increased among patients with chronic kidney disease... - Exposure to radiologic contrast media and an increased risk of treated end-stage renal diseasePaul Muntner
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana 70112, USA
Am J Med Sci 326:353-9. 2003..Radiologic contrast media can cause acute renal failure, but whether their repeated use is associated with end-stage renal disease (ESRD) is unknown... - Effect of blood pressure on early decline in kidney function among hypertensive menSuma Vupputuri
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Hypertension 42:1144-9. 2003..These results indicate that better blood pressure control might prevent the onset of chronic kidney disease among hypertensives... - Agreement of blood pressure measurements between random-zero and standard mercury sphygmomanometersWenjie Yang
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
Am J Med Sci 336:373-8. 2008.... - Effect of dietary fiber intake on blood pressure: a meta-analysis of randomized, controlled clinical trialsSeamus P Whelton
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana 70112, USA
J Hypertens 23:475-81. 2005..Our findings warrant conduct of additional clinical trials with a larger sample size and longer period of intervention to examine the effect of dietary fiber intake on BP... - Fruit and vegetable intake and risk of cardiovascular disease in US adults: the first National Health and Nutrition Examination Survey Epidemiologic Follow-up StudyLydia A Bazzano
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Am J Clin Nutr 76:93-9. 2002..CONCLUSION: We showed an inverse association of fruit and vegetable intake with the risk of cardiovascular disease and all-cause mortality in the general US population... - Dietary fiber intake and reduced risk of coronary heart disease in US men and women: the National Health and Nutrition Examination Survey I Epidemiologic Follow-up StudyLydia A Bazzano
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Arch Intern Med 163:1897-904. 2003..85 (95% CI, 0.74-0.98; P =.004 for trend) for CHD events and 0.90 (95% CI, 0.82-0.99; P =.01 for trend) for CVD events. CONCLUSION: A higher intake of dietary fiber, particularly water-soluble fiber, reduces the risk of CHD... - The risk for mild kidney function decline associated with illicit drug use among hypertensive menSuma Vupputuri
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Am J Kidney Dis 43:629-35. 2004..Few studies have examined the deleterious effect of illicit drug use on kidney function... - Agreement on nutrient intake between the databases of the First National Health and Nutrition Examination Survey and the ESHA Food ProcessorLydia A Bazzano
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA
Am J Epidemiol 156:78-85. 2002..These findings support the validity of expanding existing nutrient intake databases to explore current hypotheses, provided that food formulation, enrichment, and fortification practices have not changed substantially over time... - Global burden of hypertension: analysis of worldwide dataPatricia M Kearney
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
Lancet 365:217-23. 2005..56 billion (1.54-1.58 billion). INTERPRETATION: Hypertension is an important public-health challenge worldwide. Prevention, detection, treatment, and control of this condition should receive high priority... - Thiazide-induced dysglycemia: call for research from a working group from the national heart, lung, and blood instituteBarry L Carter
Division of Clinical and Administrative Pharmacy, Rm 527, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA
Hypertension 52:30-6. 2008 - [Prevalence, awareness, treatment and control of hypertension in Chinese adults]Dong-feng Gu
Division of Population Genetics and Prevention, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Zhonghua Yu Fang Yi Xue Za Zhi 37:84-9. 2003..It is urgently needed to improve prevention, detection and treatment for hypertension in adults... - Body weight and mortality among men and women in ChinaDongfeng Gu
Cardiovascular Institute and Fu Wai Hospital of the Chinese Academy of Medical Sciences and Peking Union Medical College, and Chinese National Center for Cardiovascular Disease Control and Research, Beijing, China
JAMA 295:776-83. 2006..The effect of underweight and obesity on mortality has not been well characterized in Asian populations... - Blood lead level is associated with elevated blood pressure in blacksSuma Vupputuri
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
Hypertension 41:463-8. 2003..08 (95% CI, 0.99 to 1.19) for black men and 1.39 (95% CI, 1.21 to 1.61) for black women. These findings suggest that increased levels of blood lead remain an important environmental risk factor for elevated blood pressure in blacks... - Prevalence, awareness, treatment, and control of hypertension in chinaDongfeng Gu
Cardiovascular Institute and Fuwai Hospital of Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Hypertension 40:920-7. 2002..These results underscore the urgent need to develop national strategies to improve prevention, detection, and treatment of hypertension in China... - Ethnic comparison of weight loss in the Trial of Nonpharmacologic Interventions in the ElderlyShiriki K Kumanyika
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
Obes Res 10:96-106. 2002..To compare weight loss in blacks and whites in the Trial of Nonpharmacologic Interventions in the Elderly (TONE)... - Increasing prevalence and low awareness, treatment and control of diabetes mellitus among Chinese adults: the InterASIA studyDongsheng Hu
Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China
Diabetes Res Clin Pract 81:250-7. 2008..To estimate the prevalence rates of impaired fasting glucose (IFG) and diabetes mellitus (DM) and to evaluate the awareness, treatment, and control of DM in the Chinese adult population... - Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Jackson T Wright
Department of Medicine, General Clinical Research Center, Cleveland, Ohio, USA
Arch Intern Med 168:207-17. 2008.... - Blood pressure and risk of cardiovascular disease in Chinese men and womenDongfeng Gu
Department of Evidence Based Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Chinese National Center for Cardiovascular Diseases, Beijing, China
Am J Hypertens 21:265-72. 2008..We examined the relationship between systolic and diastolic blood pressure (BP) and the incidence of cardiovascular disease (CVD) in a nationally representative cohort of 169,871 men and women > or = 40 years of age in China... - Central rather than overall obesity is related to diabetes in the Chinese population: the InterASIA studyDongsheng Hu
Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China
Obesity (Silver Spring) 15:2809-16. 2007..The objective was to compare central and overall obesity measurements for identifying diabetes mellitus (DM) and impaired fasting glucose (IFG) level in the Chinese population... - Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)Nancy R Cook
Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
BMJ 334:885-8. 2007..To examine the effects of reduction in dietary sodium intake on cardiovascular events using data from two completed randomised trials, TOHP I and TOHP II... - Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinoprilJackson T Wright
General Clinical Research Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
JAMA 293:1595-608. 2005..Few cardiovascular outcome data are available for blacks with hypertension treated with angiotensin-converting enzyme (ACE) inhibitors or calcium channel blockers (CCBs)... - Renal outcomes in high-risk hypertensive patients treated with an angiotensin-converting enzyme inhibitor or a calcium channel blocker vs a diuretic: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Mahboob Rahman
Division of Nephrology and Hypertension, Case Western Reserve University, University Hospitals of Cleveland, Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA
Arch Intern Med 165:936-46. 2005..Participants assigned to receive amlodipine had a higher GFR than those assigned to receive chlorthalidone, but rates of development of ESRD were not different between the groups... - Clinical events in high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the antihypertensive and lipid-lowering treatment to prevent heart attack trialFrans H H Leenen
University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Hypertension 48:374-84. 2006..Some, but not all, of these differences may be explained by less effective blood pressure control in the lisinopril arm... - Prevalence of cardiovascular disease risk factor clustering among the adult population of China: results from the International Collaborative Study of Cardiovascular Disease in Asia (InterAsia)Dongfeng Gu
Cardiovascular Institute, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medial College, Beijing, China
Circulation 112:658-65. 2005..CONCLUSIONS: Clustering of CVD risk factors is common in China. Prevention, detection, and treatment of CVD risk factor clustering should be an important component of a national strategy to reduce the increasing burden of CVD in China... - Cardiovascular outcomes in high-risk hypertensive patients stratified by baseline glomerular filtration rateMahboob Rahman
Case Western Reserve University, Cleveland, Ohio, USA
Ann Intern Med 144:172-80. 2006..Neither amlodipine nor lisinopril is superior to chlorthalidone in preventing CHD, stroke, or combined CVD, and chlorthalidone is superior to both for preventing heart failure, independent of level of renal function... - Fasting glucose levels and incident diabetes mellitus in older nondiabetic adults randomized to receive 3 different classes of antihypertensive treatment: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAJoshua I Barzilay
Kaiser Permanente of Georgia, USA
Arch Intern Med 166:2191-201. 2006..9 mmol/L) is modestly greater, but there is no conclusive or consistent evidence that this diuretic-associated increase in DM risk increases the risk of clinical events...
Research Grants
- Technology for Electronic Submission of IRB ProtocolsPaul Whelton; Fiscal Year: 2002..2.) To provide laptop computers for all IRB members so that during meetings, all members have online access to study documents, study history and reviewer comments. ..
- "RR-03-011, Extramural Research Facilities Construction*Andrew Lackner; Fiscal Year: 2004..These colonies support the research program of WaNPRC. The proposed construction is a component of a recently developed long-range strategic plan for facilities at the TNPRC. ..
- BAA-NIH-NIAID-NCRR-DMID-03-036Andrew Lackner; Fiscal Year: 2006..These objectives will be facilitated by the participation of the TNPRC in the nonhuman primate cores of the RCE applications from Regions IV and VI. ..