Francis C Lau

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia
    Francis C Lau
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Neurosci Res 85:1010-7. 2007
  2. ncbi Fruit polyphenols and their effects on neuronal signaling and behavior in senescence
    James A Joseph
    Tufts University, Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Rm 919, Boston, MA 02111, USA
    Ann N Y Acad Sci 1100:470-85. 2007
  3. ncbi Berry fruit supplementation and the aging brain
    Barbara Shukitt-Hale
    USDA ARS Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Agric Food Chem 56:636-41. 2008
  4. ncbi Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus
    Barbara Shukitt-Hale
    USDA ARS, Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Nutr Neurosci 11:172-82. 2008
  5. ncbi Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress
    Francis C Lau
    USDA ARS, Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Subcell Biochem 42:299-318. 2007
  6. ncbi The beneficial effects of fruit polyphenols on brain aging
    Francis C Lau
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Neurobiol Aging 26:128-32. 2005
  7. ncbi Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats
    Pilar Goyarzu
    National Autonomous University of Mexico, Mexico City, Mexico
    Nutr Neurosci 7:75-83. 2004
  8. ncbi Refuting "Evaluation of the genotoxitocity of (-)-hydroxycitric acid (HCA-SX) isolated from Garcinia Cambogia" by Lee and Lee, Journal of Toxicology and Environmental Health, 70:388-392, 2007
    Francis C Lau
    J Toxicol Environ Health A 71:348-9; author reply 350-1. 2008

Collaborators

Detail Information

Publications8

  1. ncbi Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia
    Francis C Lau
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Neurosci Res 85:1010-7. 2007
    ..The results suggest that blueberry polyphenols attenuate inflammatory responses of brain microglia and could be potentially useful in modulation of inflammatory conditions in the CNS...
  2. ncbi Fruit polyphenols and their effects on neuronal signaling and behavior in senescence
    James A Joseph
    Tufts University, Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Rm 919, Boston, MA 02111, USA
    Ann N Y Acad Sci 1100:470-85. 2007
    ..The purpose of this article is to discuss the benefits of these interventions in rodent models and to describe the putative molecular mechanisms involved in their benefits...
  3. ncbi Berry fruit supplementation and the aging brain
    Barbara Shukitt-Hale
    USDA ARS Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    J Agric Food Chem 56:636-41. 2008
    ..The purpose of this paper is to discuss the benefits of these interventions in rodent models and to describe the putative molecular mechanisms involved in their benefits...
  4. ncbi Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus
    Barbara Shukitt-Hale
    USDA ARS, Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Nutr Neurosci 11:172-82. 2008
    ..These results indicate that blueberry polyphenols attenuate learning impairments following neurotoxic insult and exert anti-inflammatory actions, perhaps via alteration of gene expression...
  5. ncbi Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress
    Francis C Lau
    USDA ARS, Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    Subcell Biochem 42:299-318. 2007
    ..Thus, nutritional intervention may exert therapeutic protection against age-related deficits and neurodegenerative diseases...
  6. ncbi The beneficial effects of fruit polyphenols on brain aging
    Francis C Lau
    Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Neurobiol Aging 26:128-32. 2005
    ..Furthermore, we have shown that short-term blueberry (BB) supplementation increases hippocampal plasticity. These findings are briefly reviewed in this paper...
  7. ncbi Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats
    Pilar Goyarzu
    National Autonomous University of Mexico, Mexico City, Mexico
    Nutr Neurosci 7:75-83. 2004
    ..Normalized NF-kappaB levels (averaged across regions and in several individual regions) correlated negatively and significantly with the object memory scores...
  8. ncbi Refuting "Evaluation of the genotoxitocity of (-)-hydroxycitric acid (HCA-SX) isolated from Garcinia Cambogia" by Lee and Lee, Journal of Toxicology and Environmental Health, 70:388-392, 2007
    Francis C Lau
    J Toxicol Environ Health A 71:348-9; author reply 350-1. 2008