Research Topics
| Elizabeth J JohnsonSummaryAffiliation: Tufts University Country: USA Publications
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Publications
The role of carotenoids in human healthElizabeth J Johnson
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111, USA
Nutr Clin Care 5:56-65. 2002..Until the efficacy and safety of taking supplements containing these nutrients can be determined, current dietary recommendations of diets high in fruits and vegetables are advised...- Serum carotenoid and tocopherol concentrations vary by dietary pattern among African AmericansSameera A Talegawkar
Tufts University, Boston, MA, USA
J Am Diet Assoc 108:2013-20. 2008..Intakes and biochemical concentrations of carotenoids and tocopherols have been associated with chronic diseases... - Carotenoid intakes, assessed by food-frequency questionnaires (FFQs), are associated with serum carotenoid concentrations in the Jackson Heart Study: validation of the Jackson Heart Study Delta NIRI Adult FFQsSameera A Talegawkar
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Public Health Nutr 11:989-97. 2008.... - Intake of lutein and zeaxanthin differ with age, sex, and ethnicityElizabeth J Johnson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
J Am Diet Assoc 110:1357-62. 2010..Our findings suggest that the relative intake of lutein and zeaxanthin may be important to age-related macular degeneration risk. Future studies are needed to assess the individual associations of lutein and zeaxanthin in eye health... - Supplementation with lutein or lutein plus green tea extracts does not change oxidative stress in adequately nourished older adultsLei Li
The Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr Biochem 21:544-9. 2010.... - Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin AEliot L Berson
Berman Gund Laboratory for Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Arch Ophthalmol 128:403-11. 2010..To determine whether lutein supplementation will slow visual function decline in patients with retinitis pigmentosa receiving vitamin A... - Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older womenElizabeth J Johnson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
Nutr Neurosci 11:75-83. 2008..Low dietary intake of docosahexaenoic acid (DHA) and/or foods rich in lutein may be associated with increased risk of cognitive decline in the elderly... - Determination of carotenoids in yellow maize, the effects of saponification and food preparationsTawanda Muzhingi
Dorothy J and Gerald R Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
Int J Vitam Nutr Res 78:112-20. 2008.... - Carotenoid actions and their relation to health and diseaseNorman I Krinsky
Department of Biochemistry, School of Medicine, Tufts University, 136 Harrison Avenue, Boston, MA 02111 1837, USA
Mol Aspects Med 26:459-516. 2005..Until the efficacy and safety of taking supplements containing these nutrients can be determined, current dietary recommendations of diets high in fruits and vegetables are advised... - The relationship of macular pigment optical density to serum lutein in retinitis pigmentosaMichael A Sandberg
The Berman Gund Laboratory for the Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Invest Ophthalmol Vis Sci 51:1086-91. 2010..To determine whether macular pigment optical density (MPOD) is related to serum lutein or serum zeaxanthin in patients with retinitis pigmentosa... - Metabolism of lutein and zeaxanthin in rhesus monkeys: identification of (3R,6'R)- and (3R,6'S)-3'-dehydro-lutein as common metabolites and comparison to humansGesa I Albert
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, United States
Comp Biochem Physiol B Biochem Mol Biol 151:70-8. 2008..A pathway for their formation from either lutein or zeaxanthin is proposed. These findings were comparable to results obtained with human plasma... - Age-related macular degeneration and antioxidant vitamins: recent findingsElizabeth J Johnson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
Curr Opin Clin Nutr Metab Care 13:28-33. 2010.... - Determination of 9-cis beta-carotene and zeta-carotene in biological samplesJian Qin
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr Biochem 19:612-8. 2008..1+/-0.8 and 1.1+/-0.2 nM, and 15.6+/-1.1 nM and 0.2+/-0.1 nmol/g, respectively. zetaC concentrations in the above samples were 54.2+/-7.2 and 8.3+/-1.8 nM, and 49.0+/-3.9 nM and 0.3+/-0.1 nmol/g, respectively... - Plasma antioxidant capacity in response to diets high in soy or animal protein with or without isoflavonesSonia Vega-Lopez
Cardiovascular Nutrition Laboratory and the Carotenoids and Health Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 81:43-9. 2005..Several clinical trials have suggested that soy intake decreases oxidative stress. Soy isoflavones have antioxidant properties in vitro, but results of supplementation in clinical trials are inconclusive... - Lutein bioavailability is higher from lutein-enriched eggs than from supplements and spinach in menHae-Yun Chung
Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
J Nutr 134:1887-93. 2004..The lutein bioavailability from lutein, lutein ester supplements, and spinach did not differ. This finding may have implications for dietary recommendations that may decrease the risk of certain diseases, e.g., ARMD... - Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degenerationElizabeth J Johnson
Carotenoid and Health and Lipid Metabolism Laboratories, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 83:1494S-1498S. 2006..7 fish servings/wk) is associated with an approximately 50% reduction in dementia risk. At least this amount of DHA is generally found in one commercially available 1-g fish oil capsule given daily... - Factors associated with serum retinol, alpha-tocopherol, carotenoids, and selenium in Hispanics with problems of HIV, chronic hepatitis C, and drug useJanet E Forrester
Tufts University School of Medicine, Boston, MA, US
J Public Health Policy 30:285-99. 2009..As the safety of micronutrient supplementation is not established, policy for appropriate HIV clinical care should distinguish between populations with and without hepatitis coinfection... - Obesity, lutein metabolism, and age-related macular degeneration: a web of connectionsElizabeth J Johnson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, 711 Washington St, Boston, MA 02111, USA
Nutr Rev 63:9-15. 2005..Therefore, the mechanism by which obesity is related to AMD risk may be through indirect effects on changes in lutein and zeaxanthin status and metabolism... - Nutritional manipulation of primate retinas, III: Effects of lutein or zeaxanthin supplementation on adipose tissue and retina of xanthophyll-free monkeysElizabeth J Johnson
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
Invest Ophthalmol Vis Sci 46:692-702. 2005..In this study the effects of L or Z supplementation on carotenoid levels was examined in serum, adipose tissue, and retina in rhesus monkeys with no previous intake of xanthophylls... - The influence of supplemental lutein and docosahexaenoic acid on serum, lipoproteins, and macular pigmentationElizabeth J Johnson
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
Am J Clin Nutr 87:1521-9. 2008..Lutein and docosahexaenoic acid (DHA) may protect against age-related macular degeneration (AMD). Lutein is a component of macular pigment. DHA is in the retina... - Modification of lymphocyte DNA damage by carotenoid supplementation in postmenopausal womenXianfeng Zhao
Jean Mayer USDA-Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 83:163-9. 2006.... - A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokersHelen E Gabriel
Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
Cancer Epidemiol Biomarkers Prev 15:993-9. 2006..Such effects may be important because these nutrients, as well as retinoids, are putative chemoprotective agents... - Total alpha-tocopherol intakes are associated with serum alpha-tocopherol concentrations in African American adultsSameera A Talegawkar
Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
J Nutr 137:2297-303. 2007..Supplement use was associated with higher alpha- but lower gamma-tocopherol concentration in serum. The possible health implications of this difference in relative tocopherol subtypes require further study... - Predictors of optical density of lutein and zeaxanthin in retinas of older women in the Carotenoids in Age-Related Eye Disease Study, an ancillary study of the Women's Health InitiativeJulie A Mares
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA
Am J Clin Nutr 84:1107-22. 2006..Lifestyle, diet, and physical and health predictors of xanthophyll carotenoids in the retina are poorly understood... - The selective retention of lutein, meso-zeaxanthin and zeaxanthin in the retina of chicks fed a xanthophyll-free dietYingMing Wang
Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, L465, Oregon Health and Science University, Portland, OR 972391, USA
Exp Eye Res 84:591-8. 2007..It is clear that these xanthophylls may have an essential role in the cone-rich retina of the chick as evidenced by their selective retention... - Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health InitiativeSuzen M Moeller
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53726 2336, USA
Arch Ophthalmol 126:354-64. 2008..To evaluate associations between nuclear cataract (determined from slitlamp photographs between May 2001 and January 2004) and lutein and zeaxanthin in the diet and serum in patients between 1994 and 1998 and macula between 2001 and 2004... - Lutein and age-related ocular disorders in the older adult: a reviewLisa M Renzi
Vision Science Laboratory, University of Georgia, Athens 30602, USA
J Nutr Elder 26:139-57. 2007..The mechanism by which these factors are related to risk may be partially due to adverse effects on lutein status... - Effect of dietary lutein and zeaxanthin on plasma carotenoids and their transport in lipoproteins in age-related macular degenerationWei Wang
Department of Medicine, Oregon Health and Science University, Portland, OR 97239 3098, USA
Am J Clin Nutr 85:762-9. 2007..Low dietary intakes and low plasma concentrations of lutein and zeaxanthin are associated with an increased risk of age-related macular degeneration (AMD). No studies have challenged AMD patients with a diet high in lutein and zeaxanthin... - Nutritional manipulation of primate retinas, I: effects of lutein or zeaxanthin supplements on serum and macular pigment in xanthophyll-free rhesus monkeysMartha Neuringer
Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Portalnd 97006
Invest Ophthalmol Vis Sci 45:3234-43. 2004..In this study, L or Z was fed to rhesus monkeys reared on xanthophyll-free diets to follow the accumulation of serum carotenoids and MP over time... - Macular pigment optical density in the elderly: findings in a large biracial Midsouth population sampleAlessandro Iannaccone
Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, 930 Madison Avenue, Memphis, TN 38163, USA
Invest Ophthalmol Vis Sci 48:1458-65. 2007..5 degrees of eccentricity from the fovea in elderly subjects participating in ARMA, a study of aging and age-related maculopathy (ARM) ancillary to the Health, Aging, and Body Composition (Health ABC) Study...