Matthew E Falagas

Summary

Affiliation: Tufts University
Country: USA

Publications

  1. ncbi Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review
    Petros I Rafailidis
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Virol J 5:47. 2008
  2. ncbi The significance of different formulations of aerosolized colistin
    Argyris Michalopoulos
    Crit Care 9:417-8; author reply 417-8. 2005
  3. ncbi Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, Athens, Greece
    Crit Care 9:R53-9. 2005
  4. ncbi Worldwide research productivity in critical care medicine
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, Athens, Greece
    Crit Care 9:R258-65. 2005
  5. ncbi Penetration of the English language in science: the case of a German national interdisciplinary critical care conference
    Matthew E Falagas
    Crit Care 9:655-6. 2005
  6. ncbi Methodological aspects of a GIS-based environmental health inspection program used in the Athens 2004 Olympic and Para Olympic Games
    Christos Hadjichristodoulou
    Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, Larissa, Greece
    BMC Public Health 5:93. 2005
  7. ncbi Worldwide trends in quantity and quality of published articles in the field of infectious diseases
    Ioannis A Bliziotis
    Alfa Institute of Biomedical Sciences, Athens, Greece
    BMC Infect Dis 5:16. 2005
  8. ncbi Cost-effectiveness of different study designs: an overlooked parameter in clinical research
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, Athens, Marousi 151 23, Greece
    J Clin Epidemiol 60:215-6. 2007
  9. ncbi Irrigation with antibiotic-containing solutions for the prevention and treatment of infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Clin Microbiol Infect 11:862-7. 2005
  10. ncbi The diversity of definitions of multidrug-resistant (MDR) and pandrug-resistant (PDR) Acinetobacter baumannii and Pseudomonas aeruginosa
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    J Med Microbiol 55:1619-29. 2006

Detail Information

Publications142 found, 100 shown here

  1. ncbi Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review
    Petros I Rafailidis
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Virol J 5:47. 2008
    ..In contrast, relatively little attention has been paid to the morbidity and mortality that CMV infection may cause in immunocompetent patients...
  2. ncbi The significance of different formulations of aerosolized colistin
    Argyris Michalopoulos
    Crit Care 9:417-8; author reply 417-8. 2005
  3. ncbi Aerosolized colistin for the treatment of nosocomial pneumonia due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, Athens, Greece
    Crit Care 9:R53-9. 2005
    ..There is extensive experience with use of aerosolized colistin by patients with cystic fibrosis, but there is a lack of data regarding the use of aerosolized colistin in patients without cystic fibrosis...
  4. ncbi Worldwide research productivity in critical care medicine
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, Athens, Greece
    Crit Care 9:R258-65. 2005
    ..Articles originating from Canada, Japan, and the USA had the highest mean impact factor. Canada was the leader in productivity when adjustments for gross domestic product and population were made...
  5. ncbi Penetration of the English language in science: the case of a German national interdisciplinary critical care conference
    Matthew E Falagas
    Crit Care 9:655-6. 2005
  6. ncbi Methodological aspects of a GIS-based environmental health inspection program used in the Athens 2004 Olympic and Para Olympic Games
    Christos Hadjichristodoulou
    Department of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, Larissa, Greece
    BMC Public Health 5:93. 2005
    ..In this study, GIS technology was used to help county departments of Public Health to implement environmental health surveillance for the Athens 2004 Olympic and Para Olympic Games...
  7. ncbi Worldwide trends in quantity and quality of published articles in the field of infectious diseases
    Ioannis A Bliziotis
    Alfa Institute of Biomedical Sciences, Athens, Greece
    BMC Infect Dis 5:16. 2005
    ..Trying to confront with the widespread burden of infectious diseases, the society worldwide invests considerably on research. We evaluated the contribution of different world regions in research production in Infectious Diseases...
  8. ncbi Cost-effectiveness of different study designs: an overlooked parameter in clinical research
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, Athens, Marousi 151 23, Greece
    J Clin Epidemiol 60:215-6. 2007
  9. ncbi Irrigation with antibiotic-containing solutions for the prevention and treatment of infections
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Clin Microbiol Infect 11:862-7. 2005
    ....
  10. ncbi The diversity of definitions of multidrug-resistant (MDR) and pandrug-resistant (PDR) Acinetobacter baumannii and Pseudomonas aeruginosa
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    J Med Microbiol 55:1619-29. 2006
    ..baumannii and P. aeruginosa, a fact that causes confusion to researchers and clinicians. The authors believe that at least a widely accepted definition for PDR A. baumannii and P. aeruginosa should be uniformly used worldwide...
  11. ncbi Recurrent post-sternotomy mediastinitis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Infect 52:e151-4. 2006
    ....
  12. ncbi Nephrotoxicity of intravenous colistin: a prospective evaluation
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Antimicrob Agents 26:504-7. 2005
    ..The cumulative dose of administered CMS was statistically correlated with the difference in values of serum creatinine between the end and start of CMS treatment (r = 0.6, P = 0.004 by Spearman's test)...
  13. ncbi A comparative study on the cost of new antibiotics and drugs of other therapeutic categories
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece Department of Medicine, Henry Dunant Hospital, Athens, Greece Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, United States of America
    PLoS ONE 1:e11. 2006
    ..We hypothesized that the cost of new antimicrobial agents may differ from that of other therapeutic categories and this may play a role in the stagnation of development of new antibiotics...
  14. ncbi Quinolones for treatment of human brucellosis: critical review of the evidence from microbiological and clinical studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences (AIBS, 9 Neapoleos Street, Marousi 151 23, Greece
    Antimicrob Agents Chemother 50:22-33. 2006
  15. ncbi 99mTechnetium-ciprofloxacin scintigraphy for the evaluation of spinal infections: a preliminary report
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Clin Orthop Relat Res 444:34-7. 2006
    ..Please see Guidelines for Authors for a complete description of levels of evidence...
  16. ncbi Effect of a policy for restriction of selected classes of antibiotics on antimicrobial drug cost and resistance
    M E Falagas
    Alfa of Biomedical Sciences, Atens, Greece
    J Chemother 19:178-84. 2007
    ..Our data suggest that there are considerable limitations to the programs aiming to reduce the consumption of restricted antibiotics through the approval of their use by specialists, at least in some settings...
  17. ncbi Linezolid for the treatment of adults with bone and joint infections
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Antimicrob Agents 29:233-9. 2007
    ..In addition, early identification of linezolid-induced peripheral neuropathy is necessary because this may be an irreversible event...
  18. ncbi Eighteen years of research on AIDS: contribution of and collaborations between different world regions
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    AIDS Res Hum Retroviruses 22:1199-205. 2006
    ..International collaborations should significantly increase and expand beyond the traditional cultural and political lines of international relationships...
  19. ncbi Anti-cytomegalovirus prophylaxis in solid-organ transplant recipients
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Clin Microbiol Infect 12:603-5. 2006
    ....
  20. ncbi The use of intravenous and aerosolized polymyxins for the treatment of infections in critically ill patients: a review of the recent literature
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Clin Med Res 4:138-46. 2006
    ....
  21. ncbi A prospective study of services utilization of a hospital-based employee health clinic
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Med Sci Monit 12:CR341-4. 2006
    ..Little is known regarding the utilization of services of a hospital-based employee health clinic (EHC)...
  22. ncbi Spondylodiscitis after facet joint steroid injection: a case report and review of the literature
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Scand J Infect Dis 38:295-9. 2006
    ..This iatrogenic complication should be considered in the risk-benefit analysis of facet joint diagnostic or therapeutic injections...
  23. ncbi Toxicity of polymyxins: a systematic review of the evidence from old and recent studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Crit Care 10:R27. 2006
    ..However, their use was abandoned, except in patients with cystic fibrosis, because of concerns related to toxicity...
  24. ncbi Outcome of infections due to pandrug-resistant (PDR) Gram-negative bacteria
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    BMC Infect Dis 5:24. 2005
    ..However, there are already clinical isolates of Gram-negative bacteria that are resistant to all available antibiotics, including polymyxins...
  25. ncbi Unusual climatic conditions and infectious diseases: observations made by Hippocrates
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Enferm Infecc Microbiol Clin 28:716-8. 2010
    ....
  26. ncbi Narrative review: diseases that masquerade as infectious cellulitis
    Matthew E Falagas
    Alfa HealthCare, Athens, Greece
    Ann Intern Med 142:47-55. 2005
    ..In many cases, skin biopsy is the only tool that helps identify the correct diagnosis. Special tests may also be needed...
  27. ncbi Toxicity after prolonged (more than four weeks) administration of intravenous colistin
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    BMC Infect Dis 5:1. 2005
    ..Our objective was to study the toxicity of prolonged intravenous administration of colistin (polymyxin E)...
  28. ncbi Mesh-related infections after hernia repair surgery
    M E Falagas
    Alfa HealthCare, Athens, Greece
    Clin Microbiol Infect 11:3-8. 2005
    ..The antimicrobial treatment regimen chosen initially should include coverage of Staphylococcus spp. and, particularly, Staphylococcus aureus...
  29. ncbi Linezolid versus glycopeptide or beta-lactam for treatment of Gram-positive bacterial infections: meta-analysis of randomised controlled trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Lancet Infect Dis 8:53-66. 2008
    ....
  30. ncbi Estimates of global research productivity in virology
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Med Virol 76:229-3. 2005
    ..It is evident from this study that developing regions need more help from the developed regions to enhance research infrastructure...
  31. ncbi Inhaled colistin as monotherapy for multidrug-resistant gram (-) nosocomial pneumonia: a case series
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Respir Med 103:707-13. 2009
    ..Reports of patients with polymyxin-only susceptible gram-negative nosocomial pneumonia treated with inhaled, but without concurrent intravenous, colistin are rare...
  32. ncbi Inhaled colistin for the treatment of tracheobronchitis and pneumonia in critically ill children without cystic fibrosis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Pediatr Pulmonol 45:1135-40. 2010
    ..Further studies are needed to clarify further the role of inhaled colistin in pediatric critically ill patients without cystic fibrosis...
  33. ncbi Nosocomial infections after off-pump coronary artery bypass surgery: frequency, characteristics, and risk factors
    Evangelos S Rosmarakis
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Interact Cardiovasc Thorac Surg 6:759-67. 2007
    ..The identification of risk factors for infection in combination with the appropriate evaluation of the increased CRP and procalcitonin values may help clinicians for the early diagnosis of infection after OPCABG...
  34. ncbi Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria
    Antonia C Kastoris
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Eur J Clin Pharmacol 66:359-68. 2010
    ..Fosfomycin shows no cross-resistance to other antibiotic classes. Thus, its combination with other antibiotics may potentially show synergy against resistant bacteria...
  35. ncbi Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 32:450-4. 2008
    ..Antibiotics that are ineffective in vitro may prove life-saving for some of these patients, especially combination regimens containing colistin...
  36. ncbi Antimicrobial susceptibility of Gram-positive non-urinary isolates to fosfomycin
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:497-9. 2010
    ..Fosfomycin was inactive against the 166 enterococcal isolates tested. This old antibiotic may deserve consideration for further studies and use in clinical practice, especially for S. aureus (including MRSA) infections...
  37. ncbi Exposure to quinolones is associated with carbapenem resistance among colistin-susceptible Acinetobacter baumannii blood isolates
    Petros Kopterides
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Str, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 30:409-14. 2007
    ..The appearance of Co(S)/Ca(R)A. baumannii infections represents a major threat to critically ill hospitalised patients. Exposure to fluoroquinolones is an independent risk factor for development of Co(S)/Ca(R)A. baumannii bacteraemia...
  38. ncbi Colistin therapy for microbiologically documented multidrug-resistant Gram-negative bacterial infections: a retrospective cohort study of 258 patients
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 15 123 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:194-9. 2010
    ..The findings of the largest cohort study to date on i.v. colistin show that colistin is a valuable antibiotic with acceptable nephrotoxicity and considerable effectiveness that depends on the daily dosage and infection site...
  39. ncbi Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials
    Konstantinos Z Vardakas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    CMAJ 179:1269-77. 2008
    ..We investigated whether the use of respiratory fluoroquinolones was associated with better clinical outcomes compared with the use of macrolides and beta- lactams among adults with pneumonia...
  40. ncbi Oral rifampin for eradication of Staphylococcus aureus carriage from healthy and sick populations: a systematic review of the evidence from comparative trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Am J Infect Control 35:106-14. 2007
    ..Rifampin has been used for the eradication of Staphylococcus aureus (S. aureus) colonization in various populations of healthy and sick people...
  41. ncbi Risk factors associated with the isolation of colistin-resistant gram-negative bacteria: a matched case-control study
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Crit Care Med 36:807-11. 2008
    ..We aimed to investigate the potential risk factors for the isolation of colistin-resistant Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa from hospitalized patients...
  42. ncbi Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials
    Ioannis A Bliziotis
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Mayo Clin Proc 80:1146-56. 2005
    ....
  43. ncbi Matching criteria in case-control studies in the field of antimicrobial resistance
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Microb Drug Resist 14:171-82. 2008
    ..We evaluated the available evidence from case-control studies in the field of antimicrobial resistance to identify the degree that matching was performed and the criteria used to do so...
  44. ncbi Potential of old-generation antibiotics to address current need for new antibiotics
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Marousi, Athens, Greece
    Expert Rev Anti Infect Ther 6:593-600. 2008
    ..The availability of novel genetic and molecular modification methods provides hope that the toxicity and efficacy drawbacks presented by some of these agents can be surpassed in the future...
  45. ncbi Continuous versus intermittent intravenous administration of antibiotics: a meta-analysis of randomised controlled trials
    Sofia K Kasiakou
    Alfa Institute of Biomedical Sciences (AIBS, Athens, Greece
    Lancet Infect Dis 5:581-9. 2005
    ..In an era of gradually increasing resistance among most pathogens, the potential advantages of continuous intravenous administration of antibiotics on several clinical outcomes should be further investigated...
  46. ncbi Comparison of adverse events between oral and intravenous formulations of antimicrobial agents: a systematic review of the evidence from randomized trials
    Vasilios D Kouranos
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Pharmacoepidemiol Drug Saf 18:873-9. 2009
    ....
  47. ncbi From conference abstract to full paper: differences between data presented in conferences and journals
    Evangelos S Rosmarakis
    Alfa Institute of Biomedical Sciences (AIBS, Athens, Greece
    FASEB J 19:673-80. 2005
    ..Researchers may benefit from the above findings in improving the accuracy of presented data...
  48. ncbi Short- versus long-course antibacterial therapy for community-acquired pneumonia : a meta-analysis
    George Dimopoulos
    Alfa Institute of Biomedical Sciences AIBS, Athens, GreeceDepartment of Critical Care, Attikon University Hospital, University of Athens, Athens, Greece
    Drugs 68:1841-54. 2008
    ..The evidence for traditionally recommended 7- to 14-day duration of antibacterial therapy for community-acquired pneumonia (CAP) is not well established...
  49. ncbi Epidemiologic, clinical characteristics, and risk factors for adverse outcome in multiresistant gram-negative primary bacteremia of critically ill patients
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, Athens, Greece
    Am J Infect Control 39:396-400. 2011
    ..Characteristics and burden of primary bacteremia because of multidrug-resistant (MDR) gram-negative bacteria (GNB) in intensive care unit (ICU) patients remain understudied...
  50. ncbi Fluoroquinolones versus beta-lactam based regimens for the treatment of osteomyelitis: a meta-analysis of randomized controlled trials
    Eirinaios M Karamanis
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Spine (Phila Pa 1976) 33:E297-304. 2008
    ..A meta-analysis of randomized control trials...
  51. ncbi When to include polymyxins in the empirical antibiotic regimen in critically ill patients with fever? A decision analysis approach
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Shock 27:605-9. 2007
    ..baumannii, P. aeruginosa, or K. pneumoniae) is polymyxin-only-susceptible is close to that (50%) used in our model (based on the individual hospital data)...
  52. ncbi Mortality and morbidity of HIV infected patients receiving HAART: a cohort study
    George Panos
    HIV Unit, 1st IKA Hospital, Athens, Greece
    Curr HIV Res 6:257-60. 2008
    ..Our data from the studied cohort adds to the relevant literature regarding the dramatic reduction of morbidity and mortality that occurred after the availability of HAART...
  53. ncbi Daptomycin for endocarditis and/or bacteraemia: a systematic review of the experimental and clinical evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 60:7-19. 2007
    ..Furthermore, it is a bactericidal antibiotic, a factor that is frequently considered in the choice of treatment of patients with bacteraemia and endocarditis...
  54. ncbi Early switch to oral versus intravenous antimicrobial treatment for hospitalized patients with acute pyelonephritis: a systematic review of randomized controlled trials
    Evridiki K Vouloumanou
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Curr Med Res Opin 24:3423-34. 2008
    ....
  55. ncbi Aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant Gram-negative bacteria: a prospective study
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, Department of Medicine, Athens, Greece
    Respir Med 102:407-12. 2008
    ..There is scarcity of data in the literature concerning the administration of aerosolized colistin in critically ill patients with VAP due to multidrug-resistant (MDR) Gram-negative pathogens...
  56. ncbi Urinary tract infections after pelvic floor gynecological surgery: prevalence and effect of antimicrobial prophylaxis. A systematic review
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, Marousi, 151 23 Athens, Greece
    Int Urogynecol J Pelvic Floor Dysfunct 19:1165-72. 2008
    ..6%), metronidazole plus ampicillin (20%), metronidazole (10-22.7%), or ciprofloxacin (27.2%). The use of a cephalosporin as perioperative antimicrobial prophylaxis is the optimal regimen in preventing UTIs after pelvic floor surgery...
  57. ncbi Early switch to oral treatment in patients with moderate to severe community-acquired pneumonia: a meta-analysis
    Zoe Athanassa
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Drugs 68:2469-81. 2008
    ..However, its efficacy and safety in patients with more severe forms of CAP have not been well established...
  58. ncbi Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case control study
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Antimicrob Chemother 60:1124-30. 2007
    ..Thus, the emergence of infections due to carbapenem-resistant K. pneumoniae (CRKp) is a major public health concern...
  59. ncbi A bibliometric analysis of research productivity in Parasitology by different world regions during a 9-year period (1995-2003)
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    BMC Infect Dis 6:56. 2006
    ..The objective of this study was to estimate the research productivity of different world regions in the field of Parasitology...
  60. ncbi Seasonality of mortality: the September phenomenon in Mediterranean countries
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Department of Medicine, Henry Dunant Hospital, Athens, Greece
    CMAJ 181:484-6. 2009
    ..Seasonal increases in the mortality rate have been associated with excessively cold or hot weather. We evaluated monthly patterns of mortality in selected countries...
  61. ncbi Increasing contribution of China in modern biomedical research. Statistical data from ISI Web of Knowledge
    Gregory C Makris
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Med Sci Monit 15:SR15-21. 2009
    ..However, the last two decades under the pressure of globalization Chinese medicine is turning gradually to evidence-based medicine, contributing in international biomedical research...
  62. ncbi Predictors of mortality in adult patients with ventilator-associated pneumonia: a meta-analysis
    Ilias I Siempos
    Alfa Institute of Biomedical Sciences, Henry Dunant Hospital, Athens, Greece
    Shock 33:590-601. 2010
    ....
  63. ncbi Fosfomycin for the treatment of infections caused by multidrug-resistant non-fermenting Gram-negative bacilli: a systematic review of microbiological, animal and clinical studies
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Int J Antimicrob Agents 34:111-20. 2009
    ..In conclusion, fosfomycin could have a role as a therapeutic option against MDR P. aeruginosa infections. Further research is needed to clarify the potential utility of this agent...
  64. ncbi Ciprofloxacin/metronidazole versus beta-lactam-based treatment of intra-abdominal infections: a meta-analysis of comparative trials
    Dimitrios K Matthaiou
    Alfa Institute of Biomedical Sciences (AIBS, 9 Neapoleos Street, 15123 Marousi, Athens, Greece
    Int J Antimicrob Agents 28:159-65. 2006
    ....
  65. ncbi Attributable mortality of Stenotrophomonas maltophilia infections: a systematic review of the literature
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Marousi, Athens, Greece
    Future Microbiol 4:1103-9. 2009
    ..We searched PubMed, Scopus and Cochrane and assessed the available literature regarding mortality attributable to infection with S. maltophilia...
  66. ncbi Antimicrobial susceptibility of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Enterobacteriaceae isolates to fosfomycin
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 35:240-3. 2010
    ..We suggest further evaluation of the potential clinical utility of fosfomycin against infections caused by these pathogens...
  67. ncbi Cure of persistent, post-appendectomy Klebsiella pneumoniae septicaemia with continuous intravenous administration of meropenem
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Scand J Infect Dis 38:807-10. 2006
    ..The patient was cured only after the continuous intravenous administration of meropenem of 6 g/d...
  68. ncbi Infections after endovascular coil embolization
    Thomas G Vrachliotis
    Department of Radiology, Henry Dunant Hospital, Red Cross Foundation, Athens, Greece
    J Endovasc Ther 14:805-6. 2007
  69. ncbi Effect of aminoglycoside and beta-lactam combination therapy versus beta-lactam monotherapy on the emergence of antimicrobial resistance: a meta-analysis of randomized, controlled trials
    Ioannis A Bliziotis
    Alfa Institute of Biomedical Sciences, Henry Dunant Hospital, Athens, Greece
    Clin Infect Dis 41:149-58. 2005
    ....
  70. ncbi Frequency and predictors of colonization of the respiratory tract by VIM-2-producing Pseudomonas aeruginosa in patients of a newly established intensive care unit
    Maria Horianopoulou
    Intensive Care Unit, Sismanoglio General Hospital, Athens, Greece
    J Med Microbiol 55:1435-9. 2006
    ..Use of beta-lactams, including carbapenems, was associated with subsequent colonization of the respiratory tract with MBL-positive P. aeruginosa...
  71. ncbi A 10-year survey of antifungal susceptibility of candidemia isolates from intensive care unit patients in Greece
    George Dimopoulos
    Department of Critical Care, University Hospital Attikon, Medical School, National and Kapodistrian Univeristy of Athens, Athens, Greece
    Antimicrob Agents Chemother 53:1242-4. 2009
    ..A minority of common and rare Candida species displayed decreased susceptibility to all antifungals...
  72. ncbi A bibliometric analysis of global research production in respiratory medicine
    Argyris Michalopoulos
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos St, Marousi 151 23, Greece
    Chest 128:3993-8. 2005
    ..To evaluate the contribution of different world regions in respiratory research productivity...
  73. ncbi Research contribution of different world regions in the top 50 biomedical journals (1995-2002)
    Elpidoforos S Soteriades
    Alfa Institute of Biomedical Sciences (AIBS, Athens, Greece
    FASEB J 20:29-34. 2006
    ..Canada and Western Europe share the second place while the rest of the world is far behind...
  74. ncbi A bibliometric analysis by geographic area of published research in several biomedical fields, 1995-2003
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    CMAJ 175:1389-90. 2006
    ..However, after adjustments for GDP, Canada ranked first, with the United States and Oceania following closely behind. All of the developing regions had only small research contributions in all of the biomedical fields examined...
  75. ncbi Cure of multidrug-resistant Acinetobacter baumannii bacteraemia with continuous intravenous infusion of colistin
    Argyris Michalopoulos
    Department of Intensive Care Unit, Henry Dunant' Hospital, Athens, Greece
    Scand J Infect Dis 37:142-5. 2005
    ..Continuous intravenous infusion of colistin proved to be a salvage regimen, which led to cure of a bacteraemia due to a multi-resistant isolate, without showing any allergic cross-reactivity with other antibiotics...
  76. ncbi Albendazole for the treatment of human echinococcosis: a review of comparative clinical trials
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Am J Med Sci 334:171-9. 2007
    ..Albendazole has been used in various ways in the treatment of cystic echinococcosis (CE)...
  77. ncbi Intravenous colistimethate (colistin) use in critically ill children without cystic fibrosis
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Pediatr Infect Dis J 28:123-7. 2009
    ..The increasing frequency of infections caused by multidrug-resistant (MDR) Gram-negative bacteria has led to the reappraisal of colistimethate use...
  78. ncbi Pandrug-resistant Gram-negative bacteria: the dawn of the post-antibiotic era?
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 29:630-6. 2007
    ....
  79. ncbi Risk factors for isolation of strains susceptible only to polymyxin among patients with Pseudomonas aeruginosa bacteremia
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Antimicrob Agents Chemother 50:2541-3. 2006
    ..The multivariable analysis showed that exposure to carbapenems was associated with the development of P. aeruginosa bacteremia susceptible only to polymyxin (odds ratio, 9.0; 95% confidence interval, 2.4 to 34.3; P = 0.001)...
  80. ncbi Intraventricular or intrathecal use of polymyxins in patients with Gram-negative meningitis: a systematic review of the available evidence
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 29:9-25. 2007
    ..Further studies are needed to evaluate the criteria for initiation of local central nervous system treatment with polymyxins, the optimal dosages and the role of adjuvant systemic or local therapy...
  81. ncbi Systemic colistin use in children without cystic fibrosis: a systematic review of the literature
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, 9 Neapoleos Street, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 33:503.e1-503.e13. 2009
    ..The available evidence, mainly from old case series, suggests that systemic colistin is an effective and acceptably safe option for the treatment of children without CF who have MDR Gram-negative infections...
  82. ncbi Linezolid for patients with neutropenia: are bacteriostatic agents appropriate?
    Petros I Rafailidis
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Expert Rev Anti Infect Ther 7:415-22. 2009
    ..Such data seem to justify further studies regarding the role of linezolid in this patient population...
  83. ncbi Combination therapy with intravenous colistin for management of infections due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis
    Sofia K Kasiakou
    Alfa HealthCare, 9 Neapoleos Street, Marousi, Athens 151 23, Greece
    Antimicrob Agents Chemother 49:3136-46. 2005
    ..The use of intravenous colistin for the treatment of infections due to multidrug-resistant gram-negative bacteria appears to be safe and effective...
  84. ncbi Benefit-risk assessment of linezolid for serious gram-positive bacterial infections
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    Drug Saf 31:753-68. 2008
    ....
  85. ncbi New antibiotic agents for bloodstream infections
    Paschalis I Vergidis
    Alfa Institute of Biomedical Sciences, 151 23 Marousi, Athens, Greece
    Int J Antimicrob Agents 32:S60-5. 2008
    ..Comparative trials specifically focusing on patients with bacteraemia were generally not performed; however, a proportion of patients from the reported studies did have bacteraemia...
  86. ncbi Colistin and polymyxin B in critical care
    Argyris Michalopoulos
    Intensive Care Unit, Henry Dunant Hospital, 107 Mesogeion Avenue, 11526, Athens, Greece
    Crit Care Clin 24:377-91, x. 2008
    ..Randomized controlled trials are urgently needed to further clarify various issues regarding the effectiveness and safety of polymyxins, however...
  87. ncbi Secular trends of antimicrobial resistance of blood isolates in a newly founded Greek hospital
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    BMC Infect Dis 6:99. 2006
    ..Antimicrobial resistance is one of the most challenging issues in modern medicine...
  88. ncbi Tuberculous sacroiliitis
    Elias Ch Papadopoulos
    A' Department of Orthopedics, Athens University Medical School, Athens, Greece
    Orthopedics 26:653-7; quiz 658-9. 2003
  89. ncbi Cure of post-traumatic recurrent multiresistant Gram-negative rod meningitis with intraventricular colistin
    Sofia K Kasiakou
    Department of Medicine, Henry Dunant Hospital, Athens, Greece
    J Infect 50:348-52. 2005
    ..This patient's recurrent meningitis was solved only when colistin and amikacin were given by the intraventricular in addition to the intravenous route for a long period of time, specifically 6 weeks...
  90. ncbi Article and journal impact factor in various scientific fields
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Marousi, Greece
    Am J Med Sci 335:188-91. 2008
    ..with data to answer the following simple question: What proportion of publications in the various scientific fields is published in journals with impact factor above the median and mean values of the distribution of journal impact factor?..
  91. ncbi Administration of antimicrobials via the respiratory tract for the treatment of patients with nosocomial pneumonia: a meta-analysis
    Eleni Ioannidou
    Alfa Institute of Biomedical Sciences, Athens, Greece
    J Antimicrob Chemother 60:1216-26. 2007
    ....
  92. ncbi A bibliometric analysis in the fields of preventive medicine, occupational and environmental medicine, epidemiology, and public health
    Elpidoforos S Soteriades
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    BMC Public Health 6:301. 2006
    ..In order to map the research production around the world we performed a bibliometric analysis in the above fields...
  93. ncbi Multidrug-resistant tuberculous spondylodiscitis: need for aggressive management and drug susceptibility testing of Mycobacterium tuberculosis isolates
    Petros I Rafailidis
    Alfa Institute of Biomedical Sciences (AIBS, Athens, Greece
    J Infect 52:e35-7. 2006
    ..Persistent and even invasive diagnostic work up is needed for the proper and prompt management of patients with spondylodiscitis...
  94. ncbi Linezolid for the treatment of patients with central nervous system infection
    Fotinie Ntziora
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Ann Pharmacother 41:296-308. 2007
    ..To review the available evidence regarding the use of linezolid for the treatment of patients with central nervous system (CNS) infections...
  95. ncbi Halo pin intracranial penetration and epidural abscess in a patient with a previous cranioplasty: case report and review of the literature
    P J Papagelopoulos
    First Orthopaedic Department, Athens University Medical School, Athens, Greece
    Spine (Phila Pa 1976) 26:E463-7. 2001
    ..Report of a patient with an epidural abscess after halo pin intracranial penetration at the site of a previous cranioplasty...
  96. ncbi Mesh-related infection after hernia repair: case report of an emerging type of foreign-body related infection
    I A Bliziotis
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Infection 34:46-8. 2006
    ....
  97. ncbi Probiotic bacteria and biosurfactants for nosocomial infection control: a hypothesis
    M E Falagas
    Alfa Institute of Biomedical Sciences AIBS, Athens, Greece
    J Hosp Infect 71:301-6. 2009
    ..This could potentially impede a central step in the pathogenesis of nosocomial infections...
  98. ncbi Comparison of community-acquired pneumonia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus producing the Panton-Valentine leukocidin
    K Z Vardakas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Int J Tuberc Lung Dis 13:1476-85. 2009
    ..aureus (MSSA) community-acquired pneumonia (CAP) producing the Panton-Valentine leukocidin (PVL)...
  99. ncbi Impact of methicillin resistance on mortality in Staphylococcus aureus VAP: a systematic review
    Z Athanassa
    Alfa Institute of Biomedical Sciences, 9 Neapoleos Street, 151 23 Marousi, Greece
    Eur Respir J 31:625-32. 2008
    ..However, although supported by even more limited data, adjustment for risk factors suggests that this association may not be causal, but probably due to confounders, such as the adequacy of empirical treatment and severity of illness...
  100. ncbi Trends in antimicrobial resistance of Acinetobacter baumannii clinical isolates from hospitalised patients in Greece and treatment implications
    M E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Clin Microbiol Infect 13:816-9. 2007
    ..baumannii isolates resistant to imipenem from patients hospitalised in intensive care units, medical wards and surgical wards during the study period from 0% to 91%, 8% to 71%, and 5% to 71%, respectively...
  101. ncbi Multifocal spinal and extra-spinal Mycobacterium chelonae osteomyelitis in a renal transplant recipient
    D S Korres
    First Department of Orthopaedics, Athens University Medical School, Athens, Greece
    Transpl Infect Dis 9:62-5. 2007
    ..Long-term antimicrobial chemotherapy and surgical intervention is the cornerstone of successful treatment of multifocal bone M. chelonae infection...