Research Topics
| Ethan M BalkSummaryAffiliation: Tufts-New England Medical Center Country: USA Publications
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Detail Information
Publications
Vitamin B6, B12, and folic acid supplementation and cognitive function: a systematic review of randomized trialsEthan M Balk
Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, MA 02111, USA
Arch Intern Med 167:21-30. 2007....
Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trialsEthan M Balk
Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, 750 Washington St, NEMC 63, Boston, MA 02111, USA
Diabetes Care 30:2154-63. 2007..A systematic review of the effect of chromium supplementation on glucose metabolism and lipid levels...
A collaborative effort to apply the evidence-based review process to the field of nutrition: challenges, benefits, and lessons learnedEthan M Balk
Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
Am J Clin Nutr 85:1448-56. 2007..The goals of these systematic reviews, the processes that were used, the benefits and limitations of the collaboration, and the conclusions of the reviews, including recommendations for future research, are summarized here...
Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic reviewEthan M Balk
Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, NEMC 63, Boston, MA 02111, USA
Atherosclerosis 189:19-30. 2006..The evidence regarding the effects of omega-3 fatty acids on hs-CRP is inconclusive, as are data on ALA...
Cholestanol: a serum marker to guide LDL cholesterol-lowering therapyMichel R Hoenig
Royal Brisbane and Women s Hospital, Level 5 Pigeon Holes, Herton Road, Herston, Brisbane, QLD 4029, Australia
Atherosclerosis 184:247-54. 2006..By determining whether a patient is mainly a synthesizer or absorber of cholesterol, customized regimens can be used and are expected to improve patient outcomes and minimize costs of treatment...
Reading and critically appraising systematic reviews and meta-analyses: a short primer with a focus on hepatologyEthan M Balk
Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, 750 Washington Street, NEMC #63, Boston, MA 02111, USA
J Hepatol 43:729-36. 2005
Effects of omega-3 fatty acids on coronary restenosis, intima-media thickness, and exercise tolerance: a systematic reviewEthan M Balk
Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, 750 Washington Street, NEMC 63, Boston, MA 02111, USA
Atherosclerosis 184:237-46. 2006..The dearth of long term data on fish consumption or omega-3 fatty acid supplementation on measures of cardiovascular disease risk severely limits our ability to draw definitive conclusions at this time...
Effectiveness of management strategies for renal artery stenosis: a systematic reviewEthan Balk
Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Ann Intern Med 145:901-12. 2006..Atherosclerotic renal artery stenosis is increasingly common in an aging population. Therapeutic options include medical treatment only or revascularization procedures...
Systematic review to support the development of nutrient reference intake values: challenges and solutionsMei Chung
Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA02111, USA
Am J Clin Nutr 92:273-6. 2010..The experiences described in this article can serve as a basis for future improvements in systematic reviews of nutrients and to better integrate systematic review into development of future nutrient reference values...
n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic reviewChenchen Wang
Tufts-New England Medical Center Evidence-based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, Boston, MA, USA
Am J Clin Nutr 84:5-17. 2006..The evidence for the benefits of fish oil is stronger in secondary- than in primary-prevention settings. Adverse effects appear to be minor...
Heterogeneity and lack of good quality studies limit association between folate, vitamins B-6 and B-12, and cognitive functionGowri Raman
Tufts New England Medical Center Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, MA 02111, USA
J Nutr 137:1789-94. 2007....
Reporting of systematic reviews of micronutrients and health: a critical appraisalMei Chung
Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
Am J Clin Nutr 89:1099-113. 2009..The quality of nutrition-related systematic reviews (SRs) is an unstudied but important factor affecting their usefulness...
Predictors of atrial fibrillation recurrence after radiofrequency catheter ablation: a systematic reviewEthan M Balk
Tufts Evidence based Practice Center, TuftsMedical Center, Boston, Massachusetts, USA
J Cardiovasc Electrophysiol 21:1208-16. 2010..AF Recurrence After RFA: Systematic Review...
Systematic review: Vitamin D and cardiometabolic outcomesAnastassios G Pittas
Tufts Medical Center and Friedman School of Nutrition Science and Policy, and Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
Ann Intern Med 152:307-14. 2010..Vitamin D may modify risk for cardiometabolic outcomes (type 2 diabetes, hypertension, or cardiovascular disease)...
Comparability of methods for LDL subfraction determination: A systematic reviewMei Chung
Tufts Evidence based Practice Center, Institute for Clinical Research and Health Policy Studies, Boston, MA 02111, United States
Atherosclerosis 205:342-8. 2009....
Systematic review: association of low-density lipoprotein subfractions with cardiovascular outcomesStanley Ip
Tufts Medical Center and Tufts University, Boston, Massachusetts 02111, USA
Ann Intern Med 150:474-84. 2009..Measures of low-density lipoprotein (LDL) subfractions have been proposed as an independent risk factor for cardiovascular disease...
The vulnerable atherosclerotic plaque: scope of the literatureAlawi A Alsheikh-Ali
Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, MA, USA
Ann Intern Med 153:387-95. 2010..Large prospective studies in patients with and without previous cardiovascular events during long follow-up are required to validate this concept...
Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic reviewEthan M Balk
Tufts University School of Medicine and Tufts-New England Medical Center, Boston, Massachusetts 02111, USA
Ann Intern Med 139:670-82. 2003..Overall, however, available data are insufficient to support recommendations for using nonlipid serum markers in decisions regarding statin therapy for individual patients...
Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: vitamin A as an exampleRobert Russell
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
Am J Clin Nutr 89:728-33. 2009..Ultimately, an objective, unbiased systematic review of a defined question could be useful, not only in helping to set nutrient reference values, but also for increasing the transparency of the decision making process...
Insulin therapy and acute kidney injury in critically ill patients a systematic reviewGeorge Thomas
Caritas St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
Nephrol Dial Transplant 22:2849-55. 2007..We performed a systematic review and meta-analysis to ascertain the effect of intensive insulin therapy on the incidence of acute kidney injury (AKI) in adult critically ill patients...
Short-term efficacy and safety of vasopressin receptor antagonists for treatment of hyponatremiaBertrand L Jaber
Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, MA 02135, USA
Am J Med 124:977.e1-9. 2011..We performed a meta-analysis to systematically measure efficacy and safety of vasopressin receptor antagonists (VRAs) tested in randomized controlled trials for treatment of hyponatremia...
Off-pump coronary artery bypass surgery and acute kidney injury: a meta-analysis of randomized controlled trialsVictor F Seabra
Department of Medicine, Division of Nephrology, Kidney and Dialysis Research Laboratory, St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
Clin J Am Soc Nephrol 5:1734-44. 2010..This meta-analysis compares these two surgical techniques with respect to causing acute kidney injury (AKI)...
KDOQI US commentary on the KDIGO clinical practice guideline for the prevention, diagnosis, evaluation, and treatment of hepatitis C in CKDCraig E Gordon
Tufts Center for Guideline Development and Implementation, Tufts Medical Center, Boston, MA, USA
Am J Kidney Dis 52:811-25. 2008..Research recommendations that are of particular interest to the United States are then summarized to highlight future areas of inquiry that would enable updating of the guidelines...
Gender differences in plasma lipid response to dietary fatAnnie Lapointe
Cardiovascular Nutrition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
Nutr Rev 64:234-49. 2006....
Systematic review: comparative effectiveness of radiofrequency catheter ablation for atrial fibrillationTeruhiko Terasawa
Tufts Medical Center, Boston, Massachusetts 02111, USA
Ann Intern Med 151:191-202. 2009..Atrial fibrillation is the most common sustained arrhythmia. Medical treatment often fails to control symptoms...
A systematic review of the effect of the Excebrane dialyser on biomarkers of lipid peroxidationMarie Anne Sosa
Department of Medicine, Tufts University School of Medicine, Boston, MA 02135, USA
Nephrol Dial Transplant 21:2825-33. 2006..CONCLUSION: The conversion of dialysis patients to a vitamin E-coated dialyser is associated with an improvement in circulating biomarkers of lipid peroxidation, which is of potential clinical benefit...
Pneumothorax following thoracentesis: a systematic review and meta-analysisCraig E Gordon
Renal Section, Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
Arch Intern Med 170:332-9. 2010..We aimed to determine the mean pneumothorax rate following thoracentesis and to identify risk factors for pneumothorax through a systematic review and meta-analysis...
Meta-analysis: the effect of dietary counseling for weight lossMichael L Dansinger
Tufts New England Medical Center, Boston, Massachusetts 02111, USA
Ann Intern Med 147:41-50. 2007..Dietary and lifestyle modification efforts are the primary treatments for people who are obese or overweight. The effect of dietary counseling on long-term weight change is unclear...
Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trialsEthan M Balk
Evidence-based Practice Center, Division of Clinical Care Research, Tufts University School of Medicine, New England Medical Center, 750 Washington St, No. 63, Boston, MA 02111, USA
JAMA 287:2973-82. 2002....
Therapeutic hypothermia and prevention of acute kidney injury: a meta-analysis of randomized controlled trialsPaweena Susantitaphong
Division of Nephrology, Department of Medicine, St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, MA 02135, USA
Resuscitation 83:159-67. 2012..We conducted a systematic review to ascertain the effect of therapeutic hypothermia on development of acute kidney injury (AKI) and mortality...
Short stature and functional impairment: a systematic reviewPatricia G Wheeler
Division of Genetics, Department of Pediatrics, Tufts University School of Medicine, Floating Hospital for Children, Boston, MA, USA
Arch Pediatr Adolesc Med 158:236-43. 2004..To review the available evidence on the association between primary short stature and intellectual and physical dysfunction among children...
Molecular adsorbent recirculating system as artificial support therapy for liver failure: a meta-analysisArjun Vaid
Department of Medicine, St Elizabeth s Medical Center, Boston, Massachusetts 02135, USA
ASAIO J 58:51-9. 2012..Large studies are required to assess the merit of this promising therapy on patient-centered outcomes...
Effects of statins on vascular structure and function: a systematic reviewEthan M Balk
Center for Clinical Evidence Synthesis, Institute for Clinical Research and Health Policy Studies
Am J Med 117:775-90. 2004..Statins also improve measures of vascular function, which may contribute to their clinical benefits. There is insufficient evidence to suggest that individual statins differ in their vascular effects...
Clinical practice guidelines in nephrology--for worse or for betterKatrin Uhlig
Nephrol Dial Transplant 21:1145-53. 2006
