Research Topics
| William B YoungSummaryAffiliation: Thomas Jefferson University Country: USA Publications
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Publications
Modular headache theoryW B Young
Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
Cephalalgia 21:842-9. 2001..This theory has implications for the classification, research and treatment of primary and secondary headache patients...
Should butalbital-containing analgesics be banned? YesWilliam B Young
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, USA
Curr Pain Headache Rep 6:151-5. 2002..In the 20 years since analgesic overuse headache was widely recognized, butalbital overuse has remained distressingly common. It is time to ban these agents...
Modular headache theory: a new approachWilliam B Young
Jefferson Headache Center, Thomas Jefferson University Hospital, 111 South 11th Street, Suite 8130, Philadelphia, PA 19107, USA
Curr Neurol Neurosci Rep 2:122-8. 2002..Headaches develop phenotypic stability through a process referred to as learned stereotypy. This theory has implications for the classification, research, and treatment of primary and secondary headache patients...
Restless legs syndrome and drug-induced akathisia in headache patientsWilliam B Young
Department of Neurology, Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA
CNS Spectr 8:450-6. 2003..2%) without RLS (P<.0001). Finally, we concluded that headache patients with RLS are at a greatly increased risk of developing drug-induced akathisia when treated with intravenous dopamine receptor blocking agents...
Preventive treatment of migraine: effect on weightWilliam B Young
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
Curr Pain Headache Rep 12:201-6. 2008..This article discusses the potential effects the more common headache medications have on weight...
Electronic medical records as a research tool: evaluating topiramate use at a headache centerMichael J Marmura
From the Jefferson Headache Center, Philadelphia, PA, USA
Headache 50:769-78. 2010..Electronic medical records (EMRs) are used in large healthcare centers to increase efficiency and accuracy of documentation. These databases may be utilized for clinical research or to describe clinical practices such as medication usage...
Neuroleptics and migrainePetcharat Dusitanond
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, USA
Cent Nerv Syst Agents Med Chem 9:63-70. 2009..Additional studies to clarify the mechanism of action of neuroleptics in migraine could lead to new drugs and better management of migraine...
Less is not more: underutilization of headache medications in a university hospital emergency departmentMadhavi X Gupta
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19013, USA
Headache 47:1125-33. 2007..To gain knowledge of episodic headache patients who seek care at an urban university emergency department (ED), to evaluate the care they receive and to examine the impact of the ED on these headache patients...
Mexiletine for refractory chronic daily headache: a report of nine casesMichael J Marmura
Department of Neurology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Headache 48:1506-10. 2008..To describe the use of mexiletine in the treatment of chronic daily headache in a refractory headache population...
Interictal pain in primary headache syndromesMichael J Marmura
Jefferson Headache Center, Thomas Jefferson University, 111 South 11th Street, Gibbon Building, Suite 8130, Philadelphia, PA, 19107, USA
Curr Pain Headache Rep 16:170-4. 2012..This review describes the incidence of interictal pain in primary headache disorders and suggests the significance and biological meanings of this pain...
Square one: headache education for the medical studentWilliam B Young
Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
Headache 47:351-4. 2007..Headache education for the physician begins in medical school. The American Headache Society has endorsed a curriculum and core competencies...
Acute migraine treatment: patterns of use and satisfaction in a clinical populationShahram N Malik
Thomas Jefferson University, Jefferson Headache Center, Philadelphia, PA 19107, USA
Headache 46:773-80. 2006..CONCLUSION: Migraine patients have treatment preferences. They generally want a drug that provides complete headache relief, and they are often satisfied with the current treatment options...
Study of mitochondrial DNA mutations in patients with migraine with prolonged auraTodd D Rozen
Department of Neurology, Michigan Head-Pain and Neurological Institute, Ann Arbor 48104, USA
Headache 44:674-7. 2004..From this study it appears that migraine with prolonged aura is not an oligosymptomatic form of MELAS and is not related to secondary LHON mutations. The significance of the tRNA A4336G variant is unknown...
Anticonvulsants in migraineWilliam B Young
Department of Neurology, Thomas Jefferson University Hospital, Jefferson Headache Center, 111 South 11th Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA
Curr Pain Headache Rep 8:244-50. 2004..Lamotrigine may be effective at controlling migraine aura, but has not demonstrated effectiveness at controlling migraine headache. Anticonvulsants are a useful option for the preventive treatment of migraine...
Blocking the greater occipital nerve: utility in headache managementWilliam B Young
Department of Neurology, Jefferson Headache Center, Thomas Jefferson University, 111 South Eleventh Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA
Curr Pain Headache Rep 14:404-8. 2010..A double-blind, controlled trial of nerve blocks in occipital neuralgia, which may have actually been chronic migraine, was positive...
Interictal pain in cluster headacheMichael J Marmura
Thomas Jefferson University, Philadelphia, PA, USA
Cephalalgia 30:1531-4. 2010..Cluster headache is characterized by severe attacks of unilateral pain, but many patients experience symptoms more commonly associated with migraine such as persistent pain...
New daily persistent headache: controversy in the diagnostic criteriaWilliam B Young
Thomas Jefferson University, Jefferson Headache Center, 111 South 11th Street, Philadelphia, PA 19107, USA
Curr Pain Headache Rep 15:47-50. 2011..The current International Headache Society definition excludes more than half of patients with new onset of daily headache. This exclusion due to migrainous features could have adverse scientific, diagnostic, and treatment consequences...
Dihydroergotamine for early and late treatment of migraine with cutaneous allodynia: an open-label pilot trialStephen D Silberstein
Jefferson Headache Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
Headache 47:878-85. 2007..To explore whether dihydroergotamine (D.H.E. 45) is equally effective and safe for migraine with allodynia, when administered either early or late in an attack...
Drug-induced headacheWilliam B Young
Department of Neurology, Thomas Jefferson University Hospital, Jefferson Headache Center, 111 South Eleventh Street, Gibbon Building, Suite 8130, Philadelphia, PA 19107, USA
Neurol Clin 22:173-84. 2004..The two most common classes of drugs that acutely induce headache are NO donors, typified by NTG, and PDE inhibitors, typified by sildenafil. NO donors cause a biphasic headache in migraineurs and PDE inhibitors a monophasic one...
