Research Topics
| A S HilibrandSummaryAffiliation: Thomas Jefferson University Country: USA Publications
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Detail Information
Publications
Adjacent segment degeneration and adjacent segment disease: the consequences of spinal fusion?Alan S Hilibrand
Department of Orthopaedic Surgery, Thomas Jefferson University and the Rothman Institute, 925 Chestnut Street, 5th Floor, Philadelphia, PA 19107, USA
Spine J 4:190S-194S. 2004..It remains to be seen whether restoration of motion with disc arthroplasty will alter the rate of adjacent segment degeneration or disease...- The effect of anterior cervical fusion on neck motionAlan S Hilibrand
Jefferson Medical College, Philadelphia, PA, USA
Spine (Phila Pa 1976) 31:1688-92. 2006..Prospective cohort study... - AOA Symposium. Orthopaedists partnering with other physicians to provide musculoskeletal careAlan S Hilibrand
The Rothman Institute, 925 Chestnut Street, 5th Floor, Philadelphia, PA 19107, USA
J Bone Joint Surg Am 89:2810-8. 2007 - Increased rate of arthrodesis with strut grafting after multilevel anterior cervical decompressionAlan S Hilibrand
Rothman Institute, Philadelphia, Pennsylvania 19107, USA
Spine (Phila Pa 1976) 27:146-51. 2002..Reconstruction techniques after multilevel anterior cervical decompression were retrospectively compared... - Impact of smoking on the outcome of anterior cervical arthrodesis with interbody or strut-graftingA S Hilibrand
University Hospitals Spine Institute and the Department of Orthopaedic Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
J Bone Joint Surg Am 83:668-73. 2001.... - Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesisA S Hilibrand
Department of Orthopaedic Surgery, University Hospitals Spine Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
J Bone Joint Surg Am 81:519-28. 1999.... - Surgical treatment of thoracic spinal stenosis: a 2- to 9-year follow-upM A Palumbo
University Hospitals Spine Institute, Department of Orthopaedic Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Spine (Phila Pa 1976) 26:558-66. 2001..A retrospective investigation of the results of operative treatment of patients with symptomatic thoracic spinal stenosis... - The role of pediculolaminar fixation in compromised pedicle boneA S Hilibrand
Case Western Reserve University, Cleveland, Ohio, USA
Spine (Phila Pa 1976) 21:445-51. 1996..CONCLUSIONS. Pediculolaminar fixation can augment pedicle screw fixation in pedicle bone compromised by previous stripping or significant osteoporosis or both... - Magnetic resonance imaging analysis of soft tissue disruption after flexion-distraction injuries of the subaxial cervical spineA R Vaccaro
Department of Orthopaedic Surgery and the Rothman Institute, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 4216, USA
Spine (Phila Pa 1976) 26:1866-72. 2001..A retrospective study was performed with the use of magnetic resonance imaging to evaluate the type and degree of soft tissue disruption associated with flexion-distraction injuries of the subaxial spine... - Diagnosing basilar invagination in the rheumatoid patient. The reliability of radiographic criteriaK D Riew
The University Hospitals Spine Institute, Cleveland, Ohio 44106, USA
J Bone Joint Surg Am 83:194-200. 2001..The purpose of the present study was to validate and compare the most widely accepted plain radiographic criteria for basilar invagination in this patient population... - The risk of foraminal violation and nerve root impingement after anterior placement of lumbar interbody fusion cagesB A Taylor
Department of Orthopaedic Surgery, The Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA
Spine (Phila Pa 1976) 26:100-4. 2001..CONCLUSIONS: Excessive lateral placement of lumbar interbody fusion cages may result in foraminal violation and possible nerve encroachment. The "safe zone" for centering the cages extends approximately 5 mm on either side of midline... - A comparison of three screw types for unicortical fixation in the lateral mass of the cervical spineB M Harris
Rothman Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Spine (Phila Pa 1976) 26:2427-31. 2001..The tested unicortical screws had a consistently higher load-to-failure than those previously tested under similar conditions, suggesting that currently available screws may be superior to those previously tested... - Epidural hematoma causing dense paralysis after anterior cervical corpectomy. A report of two casesJoon Y Lee
Department of Orthopaedic Surgery and the Rothman Institute, Thomas Jefferson University Hospital, 925 Chestnut Avenue, 5th Floor, Philadelphia, PA 19107, USA
J Bone Joint Surg Am 88:198-201. 2006 - Long-term magnetic resonance imaging evaluation of bioresorbable anterior cervical plate resorption following fusion for degenerative and traumatic disk disruptionAlexander R Vaccaro
Department of Orthopedic Surgery, Thomas Jefferson University, Rothman Institute, Philadelphia, PA 19107, USA
Spine (Phila Pa 1976) 31:2091-4. 2006.... - "Normal" prevertebral soft tissue swelling following elective anterior cervical decompression and fusionJames A Sanfilippo
Thomas Jefferson University, Philadelphia, PA, USA
J Spinal Disord Tech 19:399-401. 2006..However, no study to date has quantified the PSTS following elective anterior cervical decompression and fusion or the time course to resolution of that swelling... - Intraoperative neurophysiologic detection of iatrogenic C5 nerve root injury during laminectomy for cervical compression myelopathyDapeng Fan
Surgical Monitoring Associates, Inc, Bala Cynwyd, Pennsylvania 19004, USA
Spine (Phila Pa 1976) 27:2499-502. 2002..A retrospective and prospective study was conducted to investigate intraoperative neurophysiologic monitoring during cervical laminectomy to detect iatrogenic C5 nerve root palsy... - The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot studyAlexander R Vaccaro
Department of Orthopaedic Surgery, Thomas Jefferson University and the Rothman Institute, 925 Chestnut Street, 5 th Floor, Philadelphia, Pennsylvania, PA 19107, USA
Spine J 8:457-65. 2008..Previous clinical studies involving patients with degenerative spondylolisthesis have reported that the efficacy and safety of OP-1 Putty is comparable to that of autograft at both 1- and 2-year follow-up... - Development of a New Zealand white rabbit model of spinal pseudarthrosis repair and evaluation of the potential role of OP-1 to overcome pseudarthrosisJonathan N Grauer
Rothman Institute at Jefferson University, Philadelphia, PA, USA
Spine (Phila Pa 1976) 29:1405-12. 2004..Posterolateral lumbar fusions were performed in nicotine-exposed, New Zealand white rabbits. Animals that developed a pseudarthrosis were then regrafted with no graft, autograft, or osteogenic protein-1 (OP-1)... - Neurologic deficit following percutaneous vertebral stabilizationAlpesh A Patel
Department of Orthopaedic Surgery, University of Utah, Salt Lake City, UT 84108, USA
Spine (Phila Pa 1976) 32:1728-34. 2007..A retrospective review... - Quantitative prediction of spinal cord drift after cervical laminectomy and arthrodesisJoon Y Lee
University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Spine (Phila Pa 1976) 31:1795-8. 2006..Retrospective review of radiographic parameters... - Revision strategies in lumbar total disc arthroplastyAlpesh A Patel
Department of Orthopaedics, University of Utah, Salt Lake City, UT 84108, USA
Spine (Phila Pa 1976) 33:1276-83. 2008..Review of Literature... - Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusionJeff S Silber
Department of Orthopaedic Surgery, Long Island Jewish Medical Center, New Hyde Park, New York, USA
Spine (Phila Pa 1976) 28:134-9. 2003..j.a.)... - Impact of neck and arm pain on overall health statusScott D Daffner
Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA, USA
Spine 28:2030-5. 2003.... - Radiographic analysis of transforaminal lumbar interbody fusion for the treatment of adult isthmic spondylolisthesisBrian K Kwon
Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
J Spinal Disord Tech 16:469-76. 2003.... - Cervical myelopathy. current diagnostic and treatment strategiesCharles C Edwards
Maryland Spine Center, Mercy Hospital, 301 St. Paul Place, Baltimore, MD 21202, USA
Spine J 3:68-81. 2003..An alternative technique for patients with a lordotic sagittal alignment is laminoplasty, which has a proven track record of long-term good to excellent results... - The impact of adjacent level disc degeneration on health status outcomes following lumbar fusionThomas W Throckmorton
The Vanderbilt University Spine Center, Department of Orthopaedics and Rehabilitation, Nashville, Tennessee, USA
Spine 28:2546-50. 2003..Although a power analysis validated these results with 98% certainty, larger prospective studies are needed to confirm that there is no benefit to include degenerated adjacent segments in a lumbar fusion for degenerative instability... - Lumbar adjacent segment degeneration and disease after arthrodesis and total disc arthroplastyJames S Harrop
Department of Orthopaedics and Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA
Spine (Phila Pa 1976) 33:1701-7. 2008..Systematic review of published incidence of radiographic adjacent segment degeneration (ASDeg) and symptomatic adjacent segment disease (ASDis) after arthrodesis or total disc replacement... - Transforaminal lumbar interbody fusion: the effect of various instrumentation techniques on the flexibility of the lumbar spineBasil M Harris
Biomechanics Laboratory of Drexel University, Philadelphia, Pennsylvania, USA
Spine 29:E65-70. 2004..Unilateral pedicle screws frews further increased stiffness at the L4-L5 segment. However, TLIF with bilateral pedicle screws most closely approximated the L4-L5 segmental flexibility of the intact spine... - Short-term comparison of cervical fusion with static and dynamic plating using computerized motion analysisGrigory Goldberg
Department of Orthopaedic Surgery, Thomas Jefferson University and the Rothman Institute, Philadelphia, PA 19107, USA
Spine (Phila Pa 1976) 32:E371-5. 2007..This study is a retrospective review of fusion rates for cervical plates, analyzed by means of computerized analysis... - Characterization of neurophysiologic alerts during anterior cervical spine surgeryJoon Y Lee
Department of Orthopaedics, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Spine (Phila Pa 1976) 31:1916-22. 2006..A retrospective review of neurophysiologic alerts during anterior cervical surgery... - Neurophysiological identification of position-induced neurologic injury during anterior cervical spine surgeryDaniel M Schwartz
Surgical Monitoring Associates, Inc, Bala Cynwyd, Pennsylvania, USA
J Clin Monit Comput 20:437-44. 2006..This study highlights the role of tceMEP and ulnar nerve SSEP monitoring for detecting emerging peripheral nerve injury secondary to positioning in preparation for and during anterior cervical spine surgery... - Use of computed tomography to predict failure of nonoperative treatment of unilateral facet fractures of the cervical spineLeo R Spector
Department of Orthopaedic Surgery, University of Massachusetts Memorial Medical Center, Worcester, MA, USA
Spine 31:2827-35. 2006..Failure of nonoperative treatment was not observed in any patient with a fracture involving less than 40% of the height of the lateral mass or an absolute height <1 cm... - Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trialJames N Weinstein
Dartmouth Medical School, Hanover, NH, USA
JAMA 296:2441-50. 2006..Lumbar diskectomy is the most common surgical procedure performed for back and leg symptoms in US patients, but the efficacy of the procedure relative to nonoperative care remains controversial... - The adoption of a new classification system: time-dependent variation in interobserver reliability of the thoracolumbar injury severity score classification systemAlpesh A Patel
Department of Orthopaedic Surgery, University of Utah, Salt Lake City, UT 84108, USA
Spine (Phila Pa 1976) 32:E105-10. 2007..Prospective clinical assessment of the interobserver reliability of the Thoracolumbar Injury Classification and Severity Score (TLISS) in a series of consecutive patients... - The influence of fracture mechanism and morphology on the reliability and validity of two novel thoracolumbar injury classification systemsPeter G Whang
Department of Orthopaedic Surgery, Thomas Jefferson University and the Rothman Institute, Philadelphia, PA 19107, USA
Spine (Phila Pa 1976) 32:791-5. 2007..The Thoracolumbar Injury Severity Score (TLISS) and the Thoracolumbar Injury Classification and Severity Score (TLICS) were prospectively evaluated... - Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesisJames N Weinstein
Department of Orthopaedics, Dartmouth Medical School, Lebanon, NH, USA
N Engl J Med 356:2257-70. 2007..Management of degenerative spondylolisthesis with spinal stenosis is controversial. Surgery is widely used, but its effectiveness in comparison with that of nonsurgical treatment has not been demonstrated in controlled trials... - Questionnaire study of neuromonitoring availability and usage for spine surgeryDavid P Magit
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, PO Box 208071, New Haven, CT 065120 8071, USA
J Spinal Disord Tech 20:282-9. 2007..Questionnaire study presented to practicing spine surgeons... - Osteogenic protein-1 induced gene expression: evaluation in a posterolateral spinal pseudarthrosis modelAndrew P White
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT 06520-8071, USA
Spine 31:2550-5. 2006..CONCLUSIONS: In the rabbit pseudarthrosis model, gene expression data supported the hypothesis that successful pseudarthrosis repair is related to the induction of osteogenic and angiogenic cytokines by osteogenic protein-1... - The 2007 ABC Traveling Fellowship: building international orthopaedic bridgesConstance R Chu
University of Pittsburgh, 3471 Fifth Avenue, Suite 911, Pittsburgh, PA 15213, USA
J Bone Joint Surg Am 90:672-4. 2008 - Traumatic spondyloptosis of the thoracolumbar spineSanjay Yadla
Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
J Neurosurg Spine 9:145-51. 2008..To the best of the authors' knowledge, this article represents the first reported case series of these unique spinal lesions... - Agreement between surgeons and an independent panel with respect to surgical site fusion after single-level anterior cervical spine surgery: a prospective, multicenter studyRichard L Skolasky
Department of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Spine 31:E503-6. 2006..001) improvement than when the surgeon did not report this improvement. CONCLUSIONS: The finding that surgeons and independent reviewers disagreed on fusion assessment highlights the need for objective and reproducible measures of fusion... - Differences in the work-up and treatment of conditions associated with low back pain by patient gender and ethnic backgroundBrett A Taylor
Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
Spine (Phila Pa 1976) 30:359-64. 2005..Retrospective review comparing physician workup of degenerative lumbosacral pathologies between different genders and ethnic groups... - Evaluation of a novel pedicle probe for the placement of thoracic and lumbosacral pedicle screwsJonathan N Grauer
Rothman Institute, Jefferson University, Philadelphia, Pennsylvania, USA
J Spinal Disord Tech 17:492-7. 2004..SafePath (Mekanika, Boca Raton, FL) is an alternative pedicle probe designed for pedicle cannulation. This is a blunt-tipped, nonaggressive drill that seeks the cancellous portion of the pedicle... - Morphologic evaluation of cervical spine anatomy with computed tomography: anterior cervical plate fixation considerationsBrian K Kwon
Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
J Spinal Disord Tech 17:102-7. 2004..CT scanning provides excellent osseous detail for the measurement of such parameters, and with its widespread use in the evaluation of cervical disorders, large numbers of patients can be reviewed... - Predictors of paralysis in the rheumatoid cervical spine in patients undergoing total joint arthroplastyJonathan N Grauer
Department of Orthopaedics, Yale University School of Medicine, P.O. Box 208071, New Haven, CT 06520-8071, USA
J Bone Joint Surg Am 86:1420-4. 2004..Thus, while radiographic evidence of cervical instability was not infrequent in this population of patients who underwent total joint arthroplasty for rheumatoid arthritis, radiographic predictors of paralysis were much less common... - Early findings in a pilot study of anterior cervical fusion in which bioabsorbable interbody spacers were used in the treatment of cervical degenerative diseaseAlexander R Vaccaro
Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Rothman Institute, Philadelphia, Pennsylvania, USA
Neurosurg Focus 16:E7. 2004.... - Comparison of transcranial electric motor and somatosensory evoked potential monitoring during cervical spine surgeryAlan S Hilibrand
Surgical Monitoring Associates, Bala Cynwyd, Pennsylvania 19004, USA
J Bone Joint Surg Am 86:1248-53. 2004..Surgeons should strongly consider using this modality when operating on patients with cervical spondylotic myelopathy in general and on those with ossification of the posterior longitudinal ligament in particular... - Passing the Boards: can USMLE and Orthopaedic in-Training Examination scores predict passage of the ABOS Part-I examination?Gregg R Klein
Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
J Bone Joint Surg Am 86:1092-5. 2004 - Similarities and differences in the treatment of spine trauma between surgical specialties and location of practiceJonathan N Grauer
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT 06520 8071, USA
Spine (Phila Pa 1976) 29:685-96. 2004..Questionnaires administered to practicing orthopedic and neurosurgical spine surgeons from various regions of the United States and abroad... - A critical analysis of the literature regarding surgical approach and outcome for adult low-grade isthmic spondylolisthesisBrian K Kwon
Gowan and Michele Guest Neuroscience Canada Foundation CIHR, International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia, Canada
J Spinal Disord Tech 18:S30-40. 2005.... - Proposal of a modified, treatment-oriented classification of odontoid fracturesJonathan N Grauer
Rothman Institute at Thomas Jefferson University, 925 Chestnut St, Philadelphia, PA 19107 4216, USA
Spine J 5:123-9. 2005..However, uncertainty exists in the distinction between Type II and "shallow" Type III fractures. Moreover, fractures at the base of the odontoid (Anderson and D'Alonzo Type II) include a spectrum of injury patterns... - Industry support and correlation to study outcome for papers published in SpineRahul V Shah
Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut, USA
Spine 30:1099-104; discussion 1105. 2005.... - Reliability of a novel classification system for thoracolumbar injuries: the Thoracolumbar Injury Severity ScoreAlexander R Vaccaro
Thomas Jefferson University Hospital, Philadelphia, PA, USA
Spine (Phila Pa 1976) 31:S62-9; discussion S104. 2006..Prospective study of 5 spine surgeons rating 71 clinical cases of thoracolumbar spinal injuries using the Thoracolumbar Injury Severity Score (TLISS) and then re-rating the cases in a different order 1 month later... - Spinal disassociation masquerading as iatrogenic listhesis above a previous fusionArjun Saxena
Department of Orthopaedics, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA
Spine 31:E179-83. 2006..The surgical approach was modified accordingly. CONCLUSIONS: Adjacent segment degeneration next to a prior lumbar fusion may be associated with extreme instability. Treatment may require complex stabilization... - The impact of four common lumbar spine diagnoses upon overall health statusMichael A Pahl
Thomas Jefferson University Hospital, Department of Orthopaedic Surgery, 1015 Chestnut St, Suite 719, Philadelphia, PA 19107, USA
Spine J 6:125-30. 2006..These patients were also more likely to perceive their health as poor, experience decreased energy, and have more social impairment when compared with their age/gender norms... - Severe myelopathy resulting from melorheostosis of the cervicothoracic spine. A case reportSteven C Zeiller
Department of Orthopaedic Surgery, Thomas Jefferson University, 1015 Chestnut Street, Philadelphia, PA 19107, USA
J Bone Joint Surg Am 87:2759-62. 2005 - Rheumatoid arthritis in the cervical spineDavid H Kim
Department of Orthopaedic Surgery, Tufts University School of Medicine, Boston, MA, USA
J Am Acad Orthop Surg 13:463-74. 2005.... - Histological analysis of a displaced femoral ring allograft spacer filled with a recombinant human bone morphogenetic protein-2-soaked collagen sponge. A case reportJoon Y Lee
Thomas Jefferson University Hospital and The Rothman Institute, Philadelphia, Pennsylvania 19107, USA
J Bone Joint Surg Am 87:2318-22. 2005 - Acute quadriplegia following closed traction reduction of a cervical facet dislocation in the setting of ossification of the posterior longitudinal ligament: case reportDavid W Wimberley
Fondren Orthopedic Group, Texas Orthopedic Hospital, Houston, TX, USA
Spine 30:E433-8. 2005.... - Comparison of EQ-5D, HUI, and SF-36-derived societal health state values among spine patient outcomes research trial (SPORT) participantsChristine M McDonough
Dartmouth Medical School, Community and Family Medicine, Multidisciplinary Clinical Research Center in Musculoskeletal Diseases and the Center for Evaluative Clinical Sciences, Lebanon, NH 03756, USA
Qual Life Res 14:1321-32. 2005..Caution should be used when comparing health state values derived from various systems... - Image-guided spine surgery: a cadaver study comparing conventional open laminoforaminotomy and two image-guided techniques for pedicle screw placement in posterolateral fusion and nonfusion modelsMatthew S Austin
Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
Spine 27:2503-8. 2002..g., ankylosing spondylitis in which spontaneous fusions obscure surgical landmarks for pedicle access), or when used postsurgically in the setting of a posterolateral fusion...