H Saitoh

Summary

Affiliation: The Picower Institute for Medical Research
Country: USA

Publications

  1. ncbi Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3
    H Saitoh
    The Picower Institute for Medical Research, Manhasset, New York 11030, USA
    J Biol Chem 275:6252-8. 2000
  2. ncbi Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2
    H Saitoh
    Laboratory of Molecular Embryology, NICHD, National Institutes of Health, Building 18, Room 106, Bethesda, Maryland 20892 5431, USA
    Curr Biol 8:121-4. 1998
  3. ncbi Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1
    Y Kawabe
    Molecular Cell Biology Laboratory, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba ku, Sendai 980 8578, Japan
    J Biol Chem 275:20963-6. 2000
  4. ncbi RanBP2 associates with Ubc9p and a modified form of RanGAP1
    H Saitoh
    Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 5431, USA
    Proc Natl Acad Sci U S A 94:3736-41. 1997
  5. ncbi The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms
    R D Everett
    MRC Virology Unit, Glasgow G11 5JR, Scotland
    J Virol 72:6581-91. 1998
  6. ncbi A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs
    K I Kim
    School of Biological Sciences and Research Center for Cell Differentiation, Seoul National University, Seoul 151 742, Korea
    J Biol Chem 275:14102-6. 2000
  7. ncbi The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain
    T Honda
    Research Laboratory for Molecular Genetics, Niigata University, 1 Asahimachi, Niigata, Japan
    Brain Res Mol Brain Res 77:19-28. 2000
  8. ncbi Expression and regulation of the mammalian SUMO-1 E1 enzyme
    Y Azuma
    Laboratory of Molecular Embryology, NICHD, National Institutes of Health, Bethesda, Maryland 20892-5431, USA
    FASEB J 15:1825-7. 2001

Collaborators

  • R D Everett
  • S Uchida
  • Katsunori Tanaka
  • Y Azuma
  • K I Kim
  • Y Kawabe
  • T Honda
  • M M Cavenagh
  • M Dasso
  • S H Tan
  • A M Ainsztein
  • T Kumanishi
  • S Odani
  • K Kobayashi
  • Y G Watanabe
  • Y Furuichi
  • C H Chung
  • S Nishimori
  • T Suzuki
  • M Seki
  • O Imamura
  • N Shimbara
  • R Kuwano
  • K Tominaga
  • T Enomoto
  • Y J Jeon
  • T Katagiri-Abe
  • W S Wang
  • S H Baek
  • M Masuko
  • T Seki
  • I Kozakai

Detail Information

Publications8

  1. ncbi Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3
    H Saitoh
    The Picower Institute for Medical Research, Manhasset, New York 11030, USA
    J Biol Chem 275:6252-8. 2000
    ..Together, these results support the concept of important distinctions between the SUMO-2/3 and SUMO-1 conjugation pathways and suggest a role for SUMO-2/3 in the cellular responses to environmental stress...
  2. ncbi Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2
    H Saitoh
    Laboratory of Molecular Embryology, NICHD, National Institutes of Health, Building 18, Room 106, Bethesda, Maryland 20892 5431, USA
    Curr Biol 8:121-4. 1998
    ..We also show that p18(Ubc9) interacts specifically with the internal repeat domain of RanBP2, which is a substrate for SUMO-1 conjugation in Xenopus egg extracts...
  3. ncbi Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1
    Y Kawabe
    Molecular Cell Biology Laboratory, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba ku, Sendai 980 8578, Japan
    J Biol Chem 275:20963-6. 2000
    ..Finally, we confirmed by immunoblotting with an anti-SUMO-1 antibody that Wrn was covalently attached with SUMO-1...
  4. ncbi RanBP2 associates with Ubc9p and a modified form of RanGAP1
    H Saitoh
    Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 5431, USA
    Proc Natl Acad Sci U S A 94:3736-41. 1997
    ..These results suggest Ubc9p's role in cell cycle regulation may involve either modification of nuclear transport substrates or the nuclear transport machinery...
  5. ncbi The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms
    R D Everett
    MRC Virology Unit, Glasgow G11 5JR, Scotland
    J Virol 72:6581-91. 1998
    ..These observations provide a biochemical mechanism to explain the observed effects of Vmw110 on ND10 and suggest a simple yet powerful mechanism by which Vmw110 might function during virus infection...
  6. ncbi A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs
    K I Kim
    School of Biological Sciences and Research Center for Cell Differentiation, Seoul National University, Seoul 151 742, Korea
    J Biol Chem 275:14102-6. 2000
    ..These results suggest that SUSP1 may play a role in the regulation of SUMO-1-mediated cellular processes particularly related to reproduction...
  7. ncbi The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain
    T Honda
    Research Laboratory for Molecular Genetics, Niigata University, 1 Asahimachi, Niigata, Japan
    Brain Res Mol Brain Res 77:19-28. 2000
    ..In addition to its action as a virus receptor, mCAR may function naturally as an adhesion molecule involved in neuro-network formation in the developing nervous system...
  8. ncbi Expression and regulation of the mammalian SUMO-1 E1 enzyme
    Y Azuma
    Laboratory of Molecular Embryology, NICHD, National Institutes of Health, Bethesda, Maryland 20892-5431, USA
    FASEB J 15:1825-7. 2001