Research Topics
| Jilla SabetiSummaryAffiliation: The Scripps Research Institute Country: USA Publications
Research Grants
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Detail Information
Publications
Individual differences in cocaine-induced locomotor sensitization in low and high cocaine locomotor-responding rats are associated with differential inhibition of dopamine clearance in nucleus accumbensJilla Sabeti
Department of Pharmacology, University of Colorado Health Sciences Center, Denver, Colorado, USA
J Pharmacol Exp Ther 305:180-90. 2003..Our results suggest that increased DAT inhibition by cocaine is associated with locomotor sensitization and that DAT serves as a common substrate for mediating both the initial and sensitized locomotor responsiveness to cocaine...
Chloral hydrate and ethanol, but not urethane, alter the clearance of exogenous dopamine recorded by chronoamperometry in striatum of unrestrained ratsJilla Sabeti
Department of Pharmacology, 4200 East Ninth Avenue, Box C 236, University of Colorado Health Sciences Center, Denver, CO 80262, USA
Neurosci Lett 343:9-12. 2003..These results suggest differential effects of anesthetics on striatal DAT function, with chloral hydrate and ethanol significantly altering DAT activity but urethane producing only minimal effects...
Emergence of NMDAR-independent long-term potentiation at hippocampal CA1 synapses following early adolescent exposure to chronic intermittent ethanol: role for sigma-receptorsJilla Sabeti
Department of Molecular and Integrative Neurosciences MIND, The Scripps Research Institute, La Jolla, California 92037, USA
Hippocampus 18:148-68. 2008....
Kinetic analysis of striatal clearance of exogenous dopamine recorded by chronoamperometry in freely-moving ratsJilla Sabeti
Department of Pharmacology, Neuroscience Program, University of Colorado Health Sciences Center, Box C 236, 4200 East Ninth Avenue, Denver, CO 80262, USA
J Neurosci Methods 121:41-52. 2002..Our results indicate that the analysis of kinetic parameters from chronoamperometric DA signals may be useful for investigating drug-induced regulation of DAT kinetics in relation to the behavior of freely-moving rats...
Steroid pregnenolone sulfate enhances NMDA-receptor-independent long-term potentiation at hippocampal CA1 synapses: role for L-type calcium channels and sigma-receptorsJilla Sabeti
Molecular and Integrative Neurosciences Department MIND, The Scripps Research Institute, La Jolla, California 92037, USA
Hippocampus 17:349-69. 2007....
Acute cocaine differentially alters accumbens and striatal dopamine clearance in low and high cocaine locomotor responders: behavioral and electrochemical recordings in freely moving ratsJilla Sabeti
Department of Pharmacology, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
J Pharmacol Exp Ther 302:1201-11. 2002..Overall, our findings emphasize the importance of characterizing individual responses to understand more fully the range of functional consequences resulting from DAT inhibition...
Ethanol exposure in early adolescence inhibits intrinsic neuronal plasticity via sigma-1 receptor activation in hippocampal CA1 neuronsJilla Sabeti
Department of Molecular and Integrative Neurosciences, The Scripps Research Institute, La Jolla, California, USA
Alcohol Clin Exp Res 35:885-904. 2011..Large amplitude LTP following CIE exposure is mediated by sigma-1 receptors; however, not yet addressed is the role of sigma-1 receptors in modulating the intrinsic properties of neurons to alter their action potential firing during LTP...
Research Grants
- Molecular Mechanisms of Alcohol Actions in the Adolescent BrainJilla Sabeti; Fiscal Year: 2007..These experiments will provide critical insights into the molecular mechanisms responsible for the age-dependent switch in the LTP-activated pathways elicited by ethanol exposure during the adolescent period of development. ..
- Ethanol-Neurosteroid Actions on Synaptic TransmissionJilla Sabeti; Fiscal Year: 2006..Collectively, the experiments will advance our understanding of changes in neurosteroid modulation of synaptic function that may be important to the CNS actions of ethanol. ..
