Research Topics
| Timothy P RobertsSummaryAffiliation: The Children's Hospital of Philadelphia Country: USA Publications
Research Grants
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Detail Information
Publications
Developmental correlation of diffusion anisotropy with auditory-evoked responseTimothy P L Roberts
Lurie Family Foundations MEG Imaging Center, Department of Radiology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Neuroreport 20:1586-91. 2009....- Auditory magnetic mismatch field latency: a biomarker for language impairment in autismTimothy P L Roberts
Lurie Family Foundations MEG Imaging Center, Department of Radiology, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Biol Psychiatry 70:263-9. 2011..The present study assessed associations between language impairment and the amplitude and latency of the superior temporal gyrus magnetic mismatch field (MMF) in response to changes in an auditory stream of tones or vowels... - Principles and implementation of diffusion-weighted and diffusion tensor imagingTimothy P L Roberts
Department of Radiology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, 324 S 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
Pediatr Radiol 37:739-48. 2007..This in turn leads to the methodological application of diffusion tensor imaging and the subsequent postprocessing, known as tractography. The following articles deal with the clinical applications enabled by such methodologies... - Electrophysiological signatures: magnetoencephalographic studies of the neural correlates of language impairment in autism spectrum disordersTimothy P L Roberts
Department of Radiology, Children s Hospital of Philadelphia, Philadelphia, PA 19104, United States
Int J Psychophysiol 68:149-60. 2008..These findings offer promise for the comprehensive assessment of developmental neuropsychiatric disorders... - MEG detection of delayed auditory evoked responses in autism spectrum disorders: towards an imaging biomarker for autismTimothy P L Roberts
Department of Radiology, The Children s Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA
Autism Res 3:8-18. 2010..Given similar findings in language impaired and non-language impaired ASD subjects, a right-hemisphere M100 latency delay appears to be an electrophysiological endophenotype for autism... - Absence of M100 source asymmetry in autism associated with language functioningGwenda L Schmidt
Department of Radiology, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Neuroreport 20:1037-41. 2009..An association was found between language functioning and the degree of asymmetry across the two groups of children, suggesting a possible relationship between functional-structural asymmetry and language ability... - Cortical sound processing in children with autism disorder: an MEG investigationNicole M Gage
Biomagnetic Imaging Laboratory, Department of Radiology, University of California, Irvine, CA 92697 5100, USA
Neuroreport 14:2047-51. 2003..Children with autism had a much reduced range of modulation in right hemisphere sites. Findings indicate that frequency encoding mechanisms may follow a differential maturational path in autism spectrum disorder... - MagnetoencephalographyErin Simon Schwartz
Lurie Family Foundations MEG Imaging Center, Department of Radiology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
Pediatr Radiol 40:50-8. 2010..Research applications that appear promising for near-future clinical translation include the evaluation of children with autism spectrum disorder, traumatic brain injury, and schizophrenia... - Consistency of interictal and ictal onset localization using magnetoencephalography in patients with partial epilepsyLilly Tang
Department of Radiology, University of California at San Francisco, California, USA
J Neurosurg 98:837-45. 2003..These findings support the interpretation of interictal spikes on MEG as a useful and effective noninvasive method for localizing primary seizure foci... - DTI based diagnostic prediction of a disease via pattern classificationMadhura Ingalhalikar
Section of Biomedical Image Analysis, University of Pennsylvania, Philadelphia, PA, USA
Med Image Comput Comput Assist Interv 13:558-65. 2010..58% classification accuracy was obtained. The abnormality scores clearly separate the groups and the high classification accuracy indicates the prospect of using the scores as a diagnostic and prognostic marker... - Hemispheric asymmetries in auditory evoked neuromagnetic fields in response to place of articulation contrastsNicole M Gage
Biomagnetic Imaging Laboratory, Department of Radiology, University of California, San Francisco, CA, USA
Brain Res Cogn Brain Res 14:303-6. 2002..We report differential activation patterns in M100 latency, with larger differences in the right hemisphere than the left. These findings suggest that left and right auditory fields make differential contributions to speech processing... - Carotid stent delivery in an XMR suite: immediate assessment of the physiologic impact of extracranial revascularizationAlastair J Martin
Department of Radiology, University of California--San Francisco, San Francisco, CA 94143, USA
AJNR Am J Neuroradiol 26:531-7. 2005..CONCLUSION: MR imaging reliably reflects the state of the carotid artery and provides a means of monitoring and quantifying the effects of revascularization... - Increased somatosensory neuromagnetic fields ipsilateral to lesions in neurosurgical patientsTimothy P L Roberts
Box 0628, Biomagnetic Imaging Laboratory, Department of Radiology, University of California, San Francisco 94143, USA
Neuroreport 13:699-702. 2002..Biophysical and biochemical explanations implicate hyperactivity of cortical neurons close to the tumor, suggesting a possible role of MEG as a measure of tumor infiltration... - Magnetic mismatch fields elicited by vowel duration and pitch changes in Japanese words in humans: comparison between native- and non-speakers of JapaneseMayako Inouchi
English Department, San Francisco State University, San Francisco, CA, USA
Neurosci Lett 353:165-8. 2003..Automatic detection of changes in vowel shortening and pitch falling is a useful index of language-non-specific auditory memory traces... - Cortical evidence of the perceptual backward masking effect on /l/ and /r/ sounds from a following vowel in Japanese speakersSachiko Koyama
Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan
Neuroimage 18:962-74. 2003..The MMN stimulus duration effect is thus suggested to come from the backward masking of foreign consonants by subsequent vowels... - Auditory evoked fields predict language ability and impairment in childrenJanis E Oram Cardy
School of Communication Sciences and Disorders, University of Western Ontario, London, ON, Canada
Int J Psychophysiol 68:170-5. 2008.... - Cortical auditory system maturational abnormalities in children with autism disorder: an MEG investigationNicole M Gage
Biomagnetic Imaging Laboratory, San Francisco, CA, USA
Brain Res Dev Brain Res 144:201-9. 2003..M100 latency in RH increased slightly (at a rate of 0.8 ms/year) with age. Results provide evidence for a differential auditory system development in AD children which may reflect abnormalities in cortical maturational processes in AD... - Temporal resolution properties of human auditory cortex: reflections in the neuromagnetic auditory evoked M100 componentNicole Gage
Department of Cognitive Sciences, 3151 Social Science Plaza A, University of California, Irvine, CA 92697 5100, USA
Brain Res 1069:166-71. 2006..Cumulatively, results provide evidence that M100 resolution for brief fluctuations in sounds reflects temporal acuity properties that are both intrinsic to the auditory system and critical to the accurate perception of speech... - Language lateralization development in children with autism: insights from the late field magnetoencephalogramElissa J Flagg
Department of Medical Imaging, University of Toronto, 150 College St, Room 116, Toronto, Ont, Canada M5M 1G1
Neurosci Lett 386:82-7. 2005.... - The elicitation of phonological and semantic neuromagnetic field components by non-words in human auditory sentence comprehensionMayako Inouchi
English Department, San Francisco State University, San Francisco, CA, USA
Neurosci Lett 380:116-21. 2005..The elicitations of M300 and M500 components in this study support the biphasic hypothesis where a pre-lexical phonological analysis stage precedes a post-lexical semantic integration stage in lexical recognition of a native language... - Delayed mismatch field for speech and non-speech sounds in children with autismJanis E Oram Cardy
Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada
Neuroreport 16:521-5. 2005..Difficulty parsing transient differences in sounds may lead to impaired acoustic or phonological representations and subsequent language impairment in autism spectrum disorder... - Magnetoencephalography identifies rapid temporal processing deficit in autism and language impairmentJanis E Oram Cardy
Department of Medical Imaging, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
Neuroreport 16:329-32. 2005..Rapid temporal processing impairments may be fundamentally associated with impairments in language rather than autism spectrum disorder... - Vowel categorization induces departure of M100 latency from acoustic predictionTimothy P L Roberts
Department of Medical Imaging, University of Toronto, 150 College Street, Toronto, Ontario M5S 3E2, Canada
Neuroreport 15:1679-82. 2004..A theory is proposed in which phonological categorization emerges from specific spatial distribution of frequency-tuned neurons... - Prominence of M50 auditory evoked response over M100 in childhood and autismJanis E Oram Cardy
Department of Medical Imaging, University of Toronto, 150 College Street, Toronto, Ontario, M5S 2E3, Canada
Neuroreport 15:1867-70. 2004..Children with autism did not differ from control children with respect to these observations. The M50 in relation to the M100 is a robust index of early auditory system maturation suitable for future developmental investigations... - Magnetoencephalography detection of early syntactic processing in humans: comparison between L1 speakers and L2 learners of EnglishMikio Kubota
Department of English, Seijo University, 6 1 20, Seijo, Setagaya Ku, Tokyo, 157 8511, Japan
Neurosci Lett 353:107-10. 2003.... - Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison with intraoperative sensory and motor mappingHagen Schiffbauer
Department of Neurosurgery, University of Tubingen, Germany
Neurosurg Focus 15:E7. 2003..Thus, MS imaging can be considered a valuable and accurate planning adjunct in the treatment of patients with intraaxial brain tumors... - Magnetic source imaging demonstrates altered cortical distribution of function in patients with arteriovenous malformationsG Edward Vates
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
Neurosurgery 51:614-23; discussion 623-7. 2002..We used magnetic source imaging (MSI) to identify the central sulcus and to determine whether primary cortical function was shifted in a set of 30 patients. We correlated these findings with outcome after treatment... - Magnetoencephalography evidence of semantic violations in auditory sentence comprehension by native speakers of JapaneseMayako Inouchi
Department of English, San Francisco State University, CA, San Francisco, USA
Neurosci Lett 331:133-7. 2002..This semantic field component was labeled the 'SeF-M400'. The results suggest that auditory semantic mechanism is more sensitive to vowel-shortening violations than to vowel-lengthening violations... - Neuromagnetic auditory cortex responses to duration and pitch changes in tones: cross-linguistic comparisons of human subjects in directions of acoustic changesMayako Inouchi
Department of English, San Francisco State University, CA, San Francisco, USA
Neurosci Lett 331:138-42. 2002..In summary, changes in duration shortening and pitch falling are particularly salient cues for pre-attentive auditory change detection in each hemisphere... - Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison with intraoperative sensory and motor mappingHagen Schiffbauer
Department of Neurosurgery, , Germany
J Neurosurg 97:1333-42. 2002..Thus, MS imaging can be considered a valuable and accurate planning adjunct in the treatment of patients with intraaxial brain tumors... - Diffusion weighted magnetic resonance imaging in strokeTimothy P L Roberts
Department of Medical Imaging, University of Toronto, 150 College St Rm 88, Toronto, ON, Canada M5S 3E2
Eur J Radiol 45:185-94. 2003.... - Human magnetoencephalographic evidence of early syntactic responses to c-selection violations of English infinitives and gerunds by L1 and L2 speakersMikio Kubota
Department of English, Seijo University, 6 1 20, Seijo, Setagaya Ku, Tokyo 157 8511, Japan
Neurosci Lett 384:300-4. 2005..g., the incorrect *I: He postponed to use it) for either group. L2 learners may possess automatic neuronal mechanisms comparable to L1 speakers for syntactic processing of infinitive c-selection violations... - Neuro MR: protocolsDavid J Mikulis
Department of Medical Imaging, The University Health Network, The Toronto Western Hospital, Toronto, ON, Canada
J Magn Reson Imaging 26:838-47. 2007..An attempt was made to focus on basic clinical sequences that are available on most modern MR systems, with protocols employing generally accepted clinical imaging philosophies... - Human neuronal encoding of English syntactic violations as revealed by both L1 and L2 speakersMikio Kubota
Department of English, Seijo University, 6 1 20, Seijo, Setagaya Ku, Tokyo 157 8511, Japan
Neurosci Lett 368:235-40. 2004..The findings imply that L1 and L2 speakers have similar neuronal mechanisms subserving syntactic processing of such violations... - MEG detects neural consequences of anomalous nasalization in vowel-consonant pairsElissa J Flagg
Department of Languages, Literatures and Linguistics, S546 Ross Building, York University, 4700 Keele Street, Toronto, Ont, Canada M3J 1P3
Neurosci Lett 397:263-8. 2006.... - Ipsilateral representation of oral structures in human anterior parietal somatosensory cortex and integration of inputs across the midlineElizabeth A Disbrow
Department of Neurology, Center for Neuroscience, University of California, Davis, Davis, California 95616, USA
J Comp Neurol 467:487-95. 2003..The distinct pattern of differential activation for uni-vs. bilateral stimulation suggests a unique neural mechanism of integration across the midline for inputs from the mouth...
Research Grants
- Electrophysiological Signatures of Language Impairment in Autism Spectrum DisordeTimothy P Roberts; Fiscal Year: 2010....
- Electrophysiological Signatures of Language Impairment in Autism Spectrum DisordeTimothy P Roberts; Fiscal Year: 2010....