Research Topics
Species | Jae Y RoSummaryAffiliation: The Methodist Hospital Country: USA Publications
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Publications
IgG4-related sclerosing disease, an emerging entity: a review of a multi-system diseaseMukul Divatia
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
Yonsei Med J 53:15-34. 2012..IgG4-RSD may potentially be rarely associated with the development of lymphoma and carcinoma. However, the nature and pathogenesis of IgG4-RSD are yet to be fully elucidated and provide immense scope for further studies...
Plasmacytoid transitional cell carcinoma of urinary bladder: a clinicopathologic study of 9 casesJae Y Ro
Department of Pathology, The Methodist Hospital and Weill Medical College of Cornell University, Houston, TX 77030, USA
Am J Surg Pathol 32:752-7. 2008..Morphologic recognition and distinction from other plasmacytoid malignant neoplasms is critical for its clinical management and immunohistochemical studies may be required for differential diagnosis...
Epidermal growth factor receptor, cyclooxygenase-2, and BAX expression in the primary non-small cell lung cancer and brain metastasesIvan Milas
Departments of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Clin Cancer Res 9:1070-6. 2003..These three biomarkers cannot be used to predict brain metastasis. Studies of other biomarkers are under way in an effort to predict brain metastasis among patients with NSCLC...
Carcinoma of lung with rhabdoid featuresPheroze Tamboli
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Hum Pathol 35:8-13. 2004..We conclude that rhabdoid features can occur in a variety of lung tumors, including sarcomatoid carcinoma. Recognizing these lesions is important because of their possibly aggressive clinical course...
Adenocarcinoma in ectopic prostatic tissue at dome of bladder: a case report of a patient with urothelial carcinoma of the bladder and adenocarcinoma of the prostateJerad M Gardner
Department of Pathology, The Methodist Hospital, Houston, Texas, USA
Arch Pathol Lab Med 134:1271-5. 2010..We report the first case of adenocarcinoma arising in ectopic prostatic tissue within the bladder...
Muscularis mucosae versus muscularis propria in gallbladder, cystic duct, and common bile duct: smoothelin and desmin immunohistochemical studyKirtee Raparia
Department of Pathology, The Methodist Hospital, Weill Medical College, Cornell University, Houston, TX 77030, USA
Ann Diagn Pathol 14:408-12. 2010..Differentiating these anatomical muscle structures may be important for the pathologic staging of carcinoma in these organs...
Diagnostic utility of P504S/p63 cocktail, prostate-specific antigen, and prostatic acid phosphatase in verifying prostatic carcinoma involvement in seminal vesicles: a study of 57 cases of radical prostatectomy specimens of pathologic stage pT3bAaron M Harvey
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, Texas, USA
Arch Pathol Lab Med 134:983-8. 2010..p63 has positive immunoreactivity in basal cell nuclei of benign prostatic glands. Many researchers use a combination of these antibodies and their different colors...
Reappraisal of T3N0/NxM0 renal cell carcinoma: significance of extent of fat invasion, renal vein invasion, and adrenal invasionSoo Jin Jung
Department of Pathology, The Methodist Hospital and Research Institute, and Weill Medical College of Cornell University, Houston, TX 77030, USA
Hum Pathol 39:1689-94. 2008..In contrast, tumors with adrenal gland invasion carry a far worse prognosis than perinephric fat or renal vein invasion and thus supporting a separate stage category...
Sarcomatoid chromophobe renal cell carcinoma with heterologous sarcomatoid elements. A case report and review of the literatureGabriela Quiroga-Garza
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, Texas, USA
Arch Pathol Lab Med 133:1857-60. 2009..As in other sarcomatoid RCCs, this tumor behaves aggressively, with frequent distant metastases. It is important to recognize the sarcomatoid component in these tumors because of its consequential adverse prognosis for the patient...
Risk-adapted treatment for patients with clinical stage I nonseminomatous germ cell tumor of the testisRobert J Amato
Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA
Urology 63:144-8; discussion 148-9. 2004..This approach may avoid potential problems with compliance and diminish the cost of scrupulous follow-up. Our results support that surveillance for carefully selected patients at a low risk of relapse is appropriate...
Minimal or no residual prostatic adenocarcinoma on radical prostatectomy: a 5-year experience with "vanishing carcinoma phenomenon"Ognjen Kosarac
Department of Pathology, The Methodist Hospital, 6565 Fannin St, Houston, TX 77030, USA
Arch Pathol Lab Med 135:1466-70. 2011..Vanishing carcinoma phenomenon" (VC) has been defined as the finding of minute or no cancer on radical prostatectomy specimens after a positive biopsy...
Intraprostatic adipose tissue: a study of 427 whole mount radical prostatectomy specimensTipu Nazeer
Department of Pathology, Albany Medical College, Albany, NY 12208, USA
Hum Pathol 40:538-41. 2009..The small size of foci of adipose tissue and its admixture with benign glands are useful morphologic clues in distinguishing it from extraprostatic fat...
Mucinous tubular and spindle cell carcinoma of kidney is probably a variant of papillary renal cell carcinoma with spindle cell featuresSteven S Shen
Department of Pathology, The Methodist Hospital and Research Institute, Houston, TX 77030, USA
Ann Diagn Pathol 11:13-21. 2007....
Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final reportEdward S Kim
Department of Thoracic Head and Neck Medical Oncology, Thoracic Cardiovascular Surgery, Radiation Therapy, Pathology, Radiology, and Biostatistics, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Lung Cancer 44:369-79. 2004..To evaluate tumor resectability after induction chemotherapy and to determine disease-free and overall survival rates of patients with locally advanced unresectable thymoma that received a multimodal treatment regimen...
Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modalityHyun Jung Kim
The Methodist Hospital Research Institute, Houston, TX, USA
Am J Surg Pathol 33:1276-86. 2009..We consider that this technique is a feasible and practical approach for resolving difficult-to-diagnose renal tumors in clinical practice...
Number of lymph nodes examined and associated clinicopathologic factors in colorectal carcinomaSteven S Shen
Department of Pathology, The Methodist Hospital and Research Institute, Weill Medical College of Cornell University, Houston, Texas 77030, USA
Arch Pathol Lab Med 133:781-6. 2009..The number of lymph nodes recovered and examined in resection specimens has been recently shown to be critical for proper staging and is associated with survival...
Mixed epithelial and stromal tumor of kidney with malignant transformation: report of two cases and review of literatureSoo Jin Jung
Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
Hum Pathol 39:463-8. 2008..We report 2 additional cases of sarcomatous transformation in mixed epithelial and stromal tumor of the kidney...
Amyloidosis of seminal vesicles and ejaculatory ducts: a histologic analysis of 21 cases among 447 prostatectomy specimensKeun Hong Kee
Department of Pathology, The Methodist Hospital and Weill Medical College of Cornell University, Houston, TX 77030, USA
Ann Diagn Pathol 12:235-8. 2008..Amyloidosis develops subepithelially spreading to include the wall of these organs and appears to be related to advanced age. The incidence of amyloidosis of the ejaculatory system in Korean patients was higher than in US patients...
Small cell carcinoma of the kidney: a clinicopathologic study of 14 casesQiusheng Si
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Hum Pathol 42:1792-8. 2011..The frequent coexistence of small cell carcinoma with urothelial carcinoma suggests that renal small cell carcinomas may evolve from a preexisting urothelial carcinoma...
Dedifferentiated liposarcoma with peculiar meningothelial-like whorling and metaplastic bone formationJoon Seon Song
Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
Ann Diagn Pathol 13:278-84. 2009..To our knowledge, case 1 represents the first report of DDLMB with paraganglioma-like pattern. A brief literature review was made with focus on the morphologic variations of DDLMB...
Clinicopathologic and immunohistochemical characteristics of adult primary cardiac angiosarcomas: analysis of 10 casesYimin Ge
Department of Pathology, The Methodist Hospital and DeBakey Heart Center, Weill Medical College of Cornell University, Houston, TX 77030, USA
Ann Diagn Pathol 15:262-7. 2011..Surgical resection with adjuvant chemotherapy is currently the preferred treatment, and survival time appears to be inversely correlated with the tumor size and degree of regional tumor extension at the time of surgery...
Basal-like breast carcinoma: a phenotypically distinct entityBisong Haupt
Department of Pathology, Saint Louis University, 1402 S Grand Blvd, St Louis, MO 63104, USA
Arch Pathol Lab Med 134:130-3. 2010..We reviewed the literature related to basal-like breast carcinomas to better understand this clinically significant subtype of breast carcinoma...
Diagnostic utility of antibody to smoothelin in the distinction of muscularis propria from muscularis mucosae of the urinary bladder: a potential ancillary tool in the pathologic staging of invasive urothelial carcinomaGladell P Paner
Department of Pathology, Urology, Loyola University Medical Center, Maywood, IL, USA
Am J Surg Pathol 33:91-8. 2009....
Concurrent angiomyolipoma and two oncocytomas in the same kidneyArmita Bahrami
Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
Ann Diagn Pathol 11:132-6. 2007..Whether there is a pathogenetic association between AML and OC needs to be further investigated...
Immunohistochemical comparison of chordoma with chondrosarcoma, myxopapillary ependymoma, and chordoid meningiomaHyun Yee Cho
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
Appl Immunohistochem Mol Morphol 17:131-8. 2009..D2-40 was a true chondroid marker to be useful for the differential diagnosis with chordoma...
Colorectal adenocarcinoma with micropapillary pattern and its association with lymph node metastasisBisong Haupt
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
Mod Pathol 20:729-33. 2007..311). Multivariate regression analysis demonstrated that the presence of micropapillary component, as well as tumor stage and lymphovascular invasion are independent predictors of regional nodal metastasis...
Myxoid adrenal cortical neoplasmsKirtee Raparia
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
Ann Diagn Pathol 12:344-8. 2008..The usual clinical and histological features can be applied to classify the lesions as benign, borderline tumor, or malignant. In our series, there was no case with frank malignant tumor...
Thymic carcinoma with rhabdoid featuresTushar H Toprani
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Ann Diagn Pathol 7:106-11. 2003..He has since developed metastases to the pelvis and is alive with disease at 20 months of follow-up. To our knowledge, this is the first reported case of thymic carcinoma with rhabdoid features...
Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapyStephen G Swisher
Department of Thoracic and Cardiovascular Surgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 9:93-101. 2003..We designed a prospective single arm Phase II study to evaluate the feasibility and mechanisms of apoptosis induction after Ad-p53 (INGN 201) gene transfer and radiation therapy in patients with non-small cell lung cancer...
Columnar cell lesions: a consensus study among pathology traineesBisong Haupt
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
Hum Pathol 41:895-901. 2010..We conclude that appropriate tutorial training of diagnostic criteria can increase diagnostic agreement on columnar cell lesions among pathology residents, fellows, and presumably general pathologists in practice...
MUC4 expression in non-small cell lung carcinomas: relationship to tumor histology and patient survivalKun Y Kwon
Department of Pathology, Baylor College of Medicine, Houston, Tex, USA
Arch Pathol Lab Med 131:593-8. 2007..Although its tissue distribution has been studied, its utility in predicting prognosis in NSCLC is unknown...
Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experienceChul Hwan Kim
Department of Pathology, Weill Medical College of Cornell University, Methodist Hospital, Houston, TX 77030, USA
Hum Pathol 39:933-8. 2008..The survival of cardiac sarcomas is poor...
Calcifications in prostate and ejaculatory system: a study on 298 consecutive whole mount sections of prostate from radical prostatectomy or cystoprostatectomy specimensJae Hee Suh
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
Ann Diagn Pathol 12:165-70. 2008..Also, ejaculatory system calcifications are not an infrequent finding...
An overview of testicular germ cell tumorsArmita Bahrami
Department of Pathology, Baylor College of Medicine, Houston, TX, USA
Arch Pathol Lab Med 131:1267-80. 2007..More than 90% of testicular neoplasms originate from germ cells. Testicular germ cell tumors (GCTs) are a heterogeneous group of neoplasms with diverse histopathology and clinical behavior...
Recently described and emphasized entities of renal neoplasmsSteven S Shen
Department of Pathology, The Methodist Hospital, 6565 Fannin St, Houston, TX 77030, USA
Arch Pathol Lab Med 131:1234-43. 2007..In addition, rare nonepithelial renal neoplasms are identified and characterized. Familiarity with these entities will help make the most accurate diagnosis and guide the treatment and follow-up of patients with renal neoplasm...
Coexpression of EGFR and HER-2 in pancreatic ductal adenocarcinoma: a comparative study using immunohistochemistry correlated with gene amplification by fluorescencent in situ hybridizationJane Dancer
Department of Pathology, M227, The Methodist Hospital, Houston, TX 77030, USA
Oncol Rep 18:151-5. 2007..There was 60% concurrence between HER-2 gene amplification and HER-2 protein expression in this study. These results suggest that HER-2 is an important cooperating member of the EGFR signal pathway in a subset of PDAC...
Interobserver reproducibility in the diagnosis of invasive micropapillary carcinoma of the urinary tract among urologic pathologistsAnkur R Sangoi
Department of Pathology, Stanford University, Stanford, CA, USA
Am J Surg Pathol 34:1367-76. 2010..These findings suggest that more study of IMPC is needed to identify the individual pathologic features that might potentially correlate with an aggressive outcome and response to intravesical therapy...
Adenocarcinomas of the gastrointestinal tract with prominent rhabdoid featuresMojghan Amrikachi
Department of Pathology, Baylor College of Medicine, Houston, TX 77030-4009, USA
Ann Diagn Pathol 6:357-63. 2002..Recognition of the rhabdoid phenotype in gastrointestinal tract neoplasms is important because this feature is associated with poor prognosis and unresponsiveness to conventional therapy...
The number of metastatic lymph nodes in extrahepatic bile duct carcinoma as a prognostic factorSeung-Mo Hong
Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA
Am J Surg Pathol 29:1177-83. 2005..Based on the present data, we propose that nodal classification should be divided into N1 (metastasis in 1 to 4 regional lymph nodes) and N2 (metastasis in 5 or more regional lymph nodes)...
Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesotheliomaCharles Lu
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA
J Clin Oncol 23:3495-501. 2005..The optimal role of intrapleural L-NDDP therapy currently remains to be determined...
Basal cell proliferations of the prostate other than usual basal cell hyperplasia: a clinicopathologic study of 23 cases, including four carcinomas, with a proposed classificationJesse K McKenney
Department of Pathology, Emory University School of Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA
Am J Surg Pathol 28:1289-98. 2004..This study suggests that adenoid cystic carcinomas are biologically indolent following prostatectomy but have a low risk of distant metastasis...
Raymond's Paragraph System: an alternative format for the organization of gross pathology reports and its implementation in an academic teaching hospitalAnnette S Dayton
Department of Pathology, The Methodist Hospital, 6565 Fannin Street, Houston, TX 77030, USA
Arch Pathol Lab Med 133:298-302. 2009..However, little literature is available that highlights organization of the specimen gross descriptions...
Primary osteosarcoma of the breast: report of 2 casesArmita Bahrami
Department of Pathology, Baylor College of Medicine, Houston, TX, USA
Arch Pathol Lab Med 131:792-5. 2007....
Prostatic intraepithelial neoplasia: recent advancesAlberto G Ayala
Department of Pathology, The Methodist Hospital, Weill Cornell University School of Medicine, 6565 Fannin St, Room 227 Main Building, Houston, TX 77030, USA
Arch Pathol Lab Med 131:1257-66. 2007..There have been 2 putative prostatic cancer precursors, prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia (adenosis), but PIN remains as a well-known precancerous condition...
Histologic variants of infiltrating urothelial carcinomaQihui J Zhai
Department of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
Arch Pathol Lab Med 131:1244-56. 2007..The spectrum of urothelial carcinoma is broad, and variant morphologies are being reported continually. Many of these variants have been extensively documented and even established as subclasses of urothelial carcinoma...
Revolution in lung cancer: new challenges for the surgical pathologistPhilip T Cagle
Department of Pathology and Laboratory Medicine, 6565 Fannin Street, The Methodist Hospital, Houston, Texas 77030, USA
Arch Pathol Lab Med 135:110-6. 2011....
Pulmonary epithelioid hemangioendothelioma with prominent signet ring cell features mimicking metastatic adenocarcinomaElena N Hristova
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030-4009, USA
Ann Diagn Pathol 7:160-4. 2003..This case clearly indicates the importance of recognizing the cytomorphologic and histologic spectrum of this entity to avoid misdiagnosing it as either primary or metastatic adenocarcinoma...
CDX2 and MUC2 protein expression in extrahepatic bile duct carcinomaSeung-Mo Hong
Department of Pathology, University of Virginia Health System, Charlottesville, USA
Am J Clin Pathol 124:361-70. 2005..05). Expression of CDX2 and MUC2 supports that intestinal differentiation is present in specific subtypes of EBD carcinomas, and their expression status correlates with patients' overall survival...
Proliferative changes in the bronchial epithelium of former smokers treated with retinoidsWalter N Hittelman
Department of Experimental Therapeutics, The University of Texas M D Anderson Cancer Center, Box 19, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Natl Cancer Inst 99:1603-12. 2007....
Micropapillary component in lung adenocarcinoma: a distinctive histologic feature with possible prognostic significanceMitual B Amin
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
Am J Surg Pathol 26:358-64. 2002..It is also important to recognize this component in evaluating a metastasis from an unknown primary site, as it should alert the pathologist to a possible primary in the lung in addition to breast, urinary bladder, and ovary...
Undifferentiated tumor: true identity by immunohistochemistryArmita Bahrami
Department of Pathology, Baylor College of Medicine, Houston, TX, USA
Arch Pathol Lab Med 132:326-48. 2008..quot;Undifferentiated tumor" refers to a heterogeneous group of neoplasms with little or no evidence of differentiation on routine light microscopic morphology...
Association of fragile site-associated (FSA) gene expression with epithelial differentiation and tumor developmentM Tien Kuo
Department of Molecular Pathology, Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Street, Houston, TX 77030, USA
Biochem Biophys Res Commun 340:887-93. 2006..Moreover, levels of FSA expression are downregulated in tumors of these tissue origins. These results suggest that FSA also plays important roles in regulating mammalian epithelial growth and differentiation and tumor development...
Muscularis mucosae of the urinary bladder revisited with emphasis on its hyperplastic patterns: a study of a large series of cystectomy specimensFunda Vakar Lopez
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Ann Diagn Pathol 11:395-401. 2007..Pathologists should be aware of its occurrence and morphologic patterns to accurately assess the depth of invasion of bladder tumors and avoid misinterpreting HMM as the muscularis propria...
Useful immunohistochemical markers in differentiating hemangioblastoma versus metastatic renal cell carcinomaAndreana L Rivera
Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, USA
Neuropathology 30:580-5. 2010..Fli-1 failed to stain tumor cells in both HBs and RCC. Inhibin A, in combination with PAX-2, showed to be the most useful markers to differentiate HB from metastatic RCC...
Trastuzumab in combination with cisplatin and gemcitabine in patients with Her2-overexpressing, untreated, advanced non-small cell lung cancer: report of a phase II trial and findings regarding optimal identification of patients with Her2-overexpressing dRalph G Zinner
Department of Thoracic Head and Neck Medical Oncology, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA
Lung Cancer 44:99-110. 2004....
Bilateral testicular germ cell tumors: twenty-year experience at M. D. Anderson Cancer CenterMingxin Che
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Cancer 95:1228-33. 2002....
Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesionRobbin S Bubb
Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 53:1216-24. 2002..This study shows that there may be a strong correlation between biomarker expression in non-small-cell lung cancer primary tumors and their brain metastases...
Myelolipoma associated with adrenal ganglioneuromaShakil H Merchant
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, USA
Arch Pathol Lab Med 126:736-7. 2002..However, the close proximity to adrenal cortical cells within the stroma of ganglioneuroma suggests that the hormonal microenvironment may have played a role in the development of the myelolipoma...
Expression of inducible nitric oxide synthase in paired neoplastic and non-neoplastic primary prostate cell cultures and prostatectomy specimenJianzhou Wang
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Urol Oncol 21:117-22. 2003..Overexpression of iNOS mRNA and protein levels is present in moderately differentiated prostate adenocarcinoma and may contribute to prostate cancer angiogenesis, tumor growth, and tumor-related immunosuppression...
Eosinophilic angiocentric fibrosis of the sinonasal tractOgnjen Kosarac
Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
Ann Diagn Pathol 12:267-70. 2008..The 19-year-old woman is the youngest patient with EAF ever described. The patients presented with a nasal cavity mass, face pain, or nasal obstructive symptoms of long duration...
Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 casesRafael E Jimenez
Department of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Surg Pathol 26:320-7. 2002..The accurate distinction between these two entities has clear prognostic and therapeutic implications...
Extranodal follicular dendritic cell sarcoma of the head and neck region: three new cases, with a review of the literatureDavid A Biddle
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Mod Pathol 15:50-8. 2002..Correct characterization of this neoplasm is imperative given its potential for recurrence and metastasis...
Prognostic value of lymphovascular invasion in transitional cell carcinoma of upper urinary tractBumsik Hong
Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Urology 65:692-6. 2005..Because LVI is strongly associated with a poorer prognosis, systemic adjuvant therapy should be considered in the presence of LVI, even if the lymph nodes are not involved...
Nomograms for the prediction of pathologic stage of clinically localized prostate cancer in Korean menCheryn Song
Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
J Korean Med Sci 20:262-6. 2005..724, 0.626, 0.662, and 0.794, respectively. Pathologic stage of localized prostate cancer in Korean men may be predicted using the Partin table, with acceptable accuracy for OCD and LNM, but less so for ECE and SVI...
Endometrial stromal tumor with limited infiltration and probable extrauterine metastasis: report of a caseKyu Rae Kim
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138 736, Korea
Ann Diagn Pathol 9:57-60. 2005....
Synovial sarcoma of the kidney with rhabdoid features: report of three casesSun-Young Jun
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Am J Surg Pathol 28:634-7. 2004..A subset of adult rhabdoid tumors may be a rhabdoid variant of synovial sarcoma, and molecular studies to detect SYT-SSX fusion transcripts are recommended for an accurate diagnosis...
Triple synchronous neoplasms in one kidney: report of a case and review of the literatureSun-Young Jun
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Ann Diagn Pathol 7:374-80. 2003..This case is the first of its type reported in the literature...
Apoptosis in thymic epithelial tumorsSung Hye Park
Department of Pathology, Ilan Paik Hospital, Inje University, Goyang City, Korea
Pathol Res Pract 198:461-7. 2002..However, tumorigenesis of TETs is not necessarily induced by abrogation of apoptosis...
Heterogeneous expression of Ku70 in human tissues is associated with morphological and functional alterations of the nucleusEun Kyung Choi
Department of Radiation Oncology, University of Ulsan College of Medicine Asan Medical Centre, Seoul, Korea
J Pathol 198:121-30. 2002..The presented data indicate that the distribution of Ku70 in cells of human tissues is closely associated with the cell cycle, cellular differentiation, nuclear shape and the process of repair of DNA damage caused by IR...
Juxtaglomerular cell tumorChul Hwan Kim
Am J Clin Pathol 117:986; author reply 986. 2002
The morphologic spectrum of metastatic prostatic adenocarcinoma to the lung: special emphasis on histologic features overlapping with other pulmonary neoplasmsJohn N Copeland
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA
Am J Clin Pathol 117:552-7. 2002..Attention to specific discriminating histologic features, supported by immunohistochemical staining, may be useful in the differential diagnosis, which is therapeutically and prognostically critical...
Is stromal microinvasion in primary mucinous ovarian tumors with "mucin granuloma" true invasion?Kyu Rae Kim
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Am J Surg Pathol 31:546-54. 2007....
Systemic inflammatory syndrome and hepatic inflammatory cell infiltration caused by an interleukin-6 producing pheochromocytomaJeong Min Kang
Department of Internal Medicine, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea
Endocr J 52:193-8. 2005..The adrenal tumor was densely immunostained with antibody to IL-6. After resection of his adrenal tumor, his serum IL-6 level returned to normal (11 pg/ml) and all symptoms subsided with normalization of laboratory findings...
Claudin-7 is highly expressed in chromophobe renal cell carcinoma and renal oncocytomaYoo Duk Choi
Department of Pathology, Chonnam National University Medical School, 5 Hak dong, Dong Gu, Gwangju, Korea
J Korean Med Sci 22:305-10. 2007..Hypermethylation of the promoter might not be the underlying mechanism for loss of its expression in RCC. Claudin-7 can be used as a useful diagnostic marker in diagnosing chromophobe RCC and oncocytoma...
Prostate cancer in Korean men exhibits poor differentiation and is adversely related to prognosis after radical prostatectomyCheryn Song
Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Urology 68:820-4. 2006....
SMARCB1/INI1 missense mutation in mucinous carcinoma with rhabdoid featuresYong Mee Cho
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Pathol Int 56:702-6. 2006..Being aware of rhabdoid features would help diagnose this rare and aggressive malignant tumor and may provide an opportunity for further evaluation of SMARCB1/INI1 gene alteration and determination of its prognostic significance...
Juxtaglomerular cell tumor of kidney with CD34 and CD117 immunoreactivity: report of 5 casesHyun-Jung Kim
Department of Pathology, Inje University, Sanggye Paik Hospital, Seoul, Korea
Arch Pathol Lab Med 130:707-11. 2006..Juxtaglomerular cell tumor should be considered in the diagnosis of any renal tumors with epithelioid cells and negative initial cytokeratin immunohistochemistry...
Thyroid follicular carcinoma-like tumor of kidney: a case report with morphologic, immunohistochemical, and genetic analysisSoo Jin Jung
Department of Pathology, Inje University College of Medicine, Busan, Korea
Am J Surg Pathol 30:411-5. 2006..Herein, we present a new case of thyroid follicular carcinoma-like tumor of the kidney with a chromosomal study and review of the literature...
Promoter hypermethylation of the p16 gene and loss of its protein expression is correlated with tumor progression in extrahepatic bile duct carcinomasSeung-Mo Hong
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Arch Pathol Lab Med 130:33-8. 2006..Furthermore, the loss of p16 expression, with or without p16 gene promoter hypermethylation, is closely related to the tumor progression in EBD carcinomas...
Immunohistochemical and clinicopathologic characteristics of invasive ductal carcinoma of breast with micropapillary carcinoma componentMi-Jung Kim
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Arch Pathol Lab Med 129:1277-82. 2005..In both MC and non-MC components in IMC cases, no basallike immunostaining pattern was detected...
Neuroendocrine differentiation in extrahepatic bile duct carcinomas and its prognostic significanceSeung-Mo Hong
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea
Hum Pathol 36:732-40. 2005..Therefore, immunohistochemical studies for neuroendocrine differentiation may be helpful in routine pathological examinations for evaluating the survival and the prognosis of patients with EBD carcinomas...
Analysis of extrahepatic bile duct carcinomas according to the New American Joint Committee on Cancer staging system focused on tumor classification problems in 222 patientsSeung-Mo Hong
Department of Pathology, Asan Medical Center, University of Ulsan Medical College, Seoul, Korea
Cancer 104:802-10. 2005..Therefore, the authors recommended changing the current pT1 and pT2 classifications to more precise pathologic terminology...
Further characterization of the muscle layers and lamina propria of the urinary bladder by systematic histologic mapping: implications for pathologic staging of invasive urothelial carcinomaGladell P Paner
Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
Am J Surg Pathol 31:1420-9. 2007....
