Gireesh Rajashekara

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi Occurrence of the invasion associated marker (iam) in Campylobacter jejuni isolated from cattle
    Yasser M Sanad
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    BMC Res Notes 4:570. 2011
  2. ncbi Functional characterization of the twin-arginine translocation system in Campylobacter jejuni
    Gireesh Rajashekara
    Food Animal Health Research Program, Ohio Agricultural Research Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio 44691, USA
    Foodborne Pathog Dis 6:935-45. 2009
  3. ncbi Genomic island 2 of Brucella melitensis is a major virulence determinant: functional analyses of genomic islands
    Gireesh Rajashekara
    Food Animal Health Research Program, Ohio Agricultural Research Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    J Bacteriol 190:6243-52. 2008
  4. ncbi Contribution of TAT system translocated PhoX to Campylobacter jejuni phosphate metabolism and resilience to environmental stresses
    Mary Drozd
    Food Animal Health Research Program, Department of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America
    PLoS ONE 6:e26336. 2011
  5. ncbi Genotypic and phenotypic properties of cattle-associated Campylobacter and their implications to public health in the USA
    Yasser M Sanad
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America
    PLoS ONE 6:e25778. 2011
  6. ncbi Polyphosphate kinase 2: a novel determinant of stress responses and pathogenesis in Campylobacter jejuni
    Dharanesh Gangaiah
    Department of Veterinary Preventive Medicine, The Ohio State University, Ohio Agricultural Research Development Center, Wooster, Ohio, United States of America
    PLoS ONE 5:e12142. 2010
  7. ncbi Importance of polyphosphate kinase 1 for Campylobacter jejuni viable-but-nonculturable cell formation, natural transformation, and antimicrobial resistance
    Dharanesh Gangaiah
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    Appl Environ Microbiol 75:7838-49. 2009
  8. ncbi The twin-arginine translocation system: contributions to the pathobiology of Campylobacter jejuni
    Issmat I Kassem
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    Future Microbiol 6:1315-27. 2011
  9. ncbi Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model
    Gourapura J Renukaradhya
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, 1680 Madison Ave, Wooster, OH 44691, USA
    J Clin Immunol 31:228-39. 2011
  10. ncbi A quantitative polymerase chain reaction assay for detection and quantification of Lawsonia intracellularis
    Mary Drozd
    Food Animal Health Research Program, Ohio Agricultural Research Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    J Vet Diagn Invest 22:265-9. 2010

Collaborators

  • Issmat I Kassem
  • Qijing Zhang
  • Jun Lin
  • Abdul Rauf
  • Mahesh Khatri
  • Bradley D Anderson
  • Menachem Banai
  • J D Glasner
  • Dharanesh Gangaiah
  • Yasser M Sanad
  • Mary Drozd
  • Zhe Liu
  • Gourapura J Renukaradhya
  • Jeffrey T Lejeune
  • Wondwossen Gebreyes
  • Amy A Rambow-Larsen
  • Trevor E Swartz
  • Gary A Splitter
  • Seung-Hun Baek
  • Xiangming Li
  • Moriya Tsuji
  • Melanie Abley
  • Cordelia Manickam
  • Varun Dwivedi
  • Jesús Arcos
  • Jordi B Torrelles
  • Yasser Sanad
  • Gary Splitter
  • Erik Petersen
  • Marcus A Frederickson
  • Fernando A Goldbaum
  • Tong-Seung Tseng
  • Mary Beth Mudgett
  • Rodolfo A Ugalde
  • Jung Gun Kim
  • Diego J Comerci
  • Tong Seung Tseng
  • Jung-Gun Kim
  • Gastón Paris
  • Winslow R Briggs
  • Roberto A Bogomolni
  • James P Shapleigh

Detail Information

Publications19

  1. ncbi Occurrence of the invasion associated marker (iam) in Campylobacter jejuni isolated from cattle
    Yasser M Sanad
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    BMC Res Notes 4:570. 2011
    ..abstract:..
  2. ncbi Functional characterization of the twin-arginine translocation system in Campylobacter jejuni
    Gireesh Rajashekara
    Food Animal Health Research Program, Ohio Agricultural Research Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, Ohio 44691, USA
    Foodborne Pathog Dis 6:935-45. 2009
    ..jejuni to sustain colonization in chickens. These findings suggest that the TAT pathway affects Campylobacter physiology and contributes to stress responses, allowing this fastidious pathogen to adapt to various environmental conditions...
  3. ncbi Genomic island 2 of Brucella melitensis is a major virulence determinant: functional analyses of genomic islands
    Gireesh Rajashekara
    Food Animal Health Research Program, Ohio Agricultural Research Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    J Bacteriol 190:6243-52. 2008
    ..Our study also indicated that the rough LPS resulting from the GI-2 deletion may affect pathogen-associated molecular pattern recognition by Toll-like receptors...
  4. ncbi Contribution of TAT system translocated PhoX to Campylobacter jejuni phosphate metabolism and resilience to environmental stresses
    Mary Drozd
    Food Animal Health Research Program, Department of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America
    PLoS ONE 6:e26336. 2011
    ..The qRT-PCR of the ?phoX mutant revealed transcriptional changes that suggest potential mechanisms for the increased biofilm phenotype...
  5. ncbi Genotypic and phenotypic properties of cattle-associated Campylobacter and their implications to public health in the USA
    Yasser M Sanad
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of America
    PLoS ONE 6:e25778. 2011
    ..Taken together, our results highlight the importance of cattle as a potential reservoir for clinically important Campylobacter...
  6. ncbi Polyphosphate kinase 2: a novel determinant of stress responses and pathogenesis in Campylobacter jejuni
    Dharanesh Gangaiah
    Department of Veterinary Preventive Medicine, The Ohio State University, Ohio Agricultural Research Development Center, Wooster, Ohio, United States of America
    PLoS ONE 5:e12142. 2010
    ..Campylobacter jejuni, an important cause of foodborne gastroenteritis in humans, possesses homologs of both ppk1 and ppk2. ppk1 has been previously shown to impact the pathobiology of C. jejuni...
  7. ncbi Importance of polyphosphate kinase 1 for Campylobacter jejuni viable-but-nonculturable cell formation, natural transformation, and antimicrobial resistance
    Dharanesh Gangaiah
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    Appl Environ Microbiol 75:7838-49. 2009
    ..jejuni. These findings highlight the potential of PPK1 as a novel target for therapeutic interventions...
  8. ncbi The twin-arginine translocation system: contributions to the pathobiology of Campylobacter jejuni
    Issmat I Kassem
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    Future Microbiol 6:1315-27. 2011
    ..These studies as well as the absence of Tat homologs in the sequenced genomes of animals suggest that the Tat system might pose an attractive target for therapeutics against C. jejuni...
  9. ncbi Functional invariant NKT cells in pig lungs regulate the airway hyperreactivity: a potential animal model
    Gourapura J Renukaradhya
    Food Animal Health Research Program, Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, 1680 Madison Ave, Wooster, OH 44691, USA
    J Clin Immunol 31:228-39. 2011
    ..Thus, baby pigs may serve as a useful animal model to study iNKT cell-mediated AHR caused by various environmental and microbial CD1d-specific glycolipid antigens...
  10. ncbi A quantitative polymerase chain reaction assay for detection and quantification of Lawsonia intracellularis
    Mary Drozd
    Food Animal Health Research Program, Ohio Agricultural Research Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH 44691, USA
    J Vet Diagn Invest 22:265-9. 2010
    ....
  11. ncbi Unraveling Brucella genomics and pathogenesis in immunocompromised IRF-1-/- mice
    Gireesh Rajashekara
    Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 53706, USA
    Am J Reprod Immunol 54:358-68. 2005
    ..CONCLUSIONS: Genomic islands contribute to Brucella pathogenicity. Biophotonic imaging suggests that Brucella dissemination in mice parallels acute and chronic infections of humans...
  12. ncbi Denitrification genes regulate Brucella virulence in mice
    Seung-Hun Baek
    Department of Microbiology, Wing Hall, Cornell University, Ithaca, NY 14853-8101, USA
    J Bacteriol 186:6025-31. 2004
    ..neotomae containing nirK, nirV, and nnrA and those infected with wild-type B. neotomae. The wild-type strain killed all the infected mice, whereas most of the mice infected with B. neotomae containing nirK, nirV, and nnrA survived...
  13. ncbi Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections
    Gireesh Rajashekara
    Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison, 53706, USA
    Cell Microbiol 7:1459-73. 2005
    ..Our approach facilitates identifying virulence determinants that may control tissue specific replication and may help develop therapeutics to overcome Brucella-induced chronic debilitating conditions...
  14. ncbi Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella
    Amy A Rambow-Larsen
    Department of Pathobiological Sciences, University of Wisconsin Madison, 1656 Linden Dr, Madison, WI 53706, USA
    J Bacteriol 190:3274-82. 2008
    ..melitensis, while the vjbR mutant was defective for systemic spread in IRF-1(-/-) mice, suggesting that these regulators are not functionally redundant but that they converge in a common pathway regulating bacterial processes...
  15. ncbi Blue-light-activated histidine kinases: two-component sensors in bacteria
    Trevor E Swartz
    Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA, USA
    Science 317:1090-3. 2007
    ..abortus was stimulated by light in the wild type but was limited in photochemically inactive and null mutants, indicating that the flavin-containing histidine kinase functions as a photoreceptor regulating B. abortus virulence...
  16. ncbi Brucella: functional genomics and host-pathogen interactions
    Gireesh Rajashekara
    Department of Animal Health and Biomedical Sciences, 1656 Linden Dr, University of Wisconsin-Madison, Madison, WI 53706, USA
    Anim Health Res Rev 7:1-11. 2006
    ..Biophotonic imaging of Brucella infections revealed sites of bacterial localization similar to human infections and different patterns of infection by attenuated or virulent Brucella...
  17. ncbi Attenuated bioluminescent Brucella melitensis mutants GR019 (virB4), GR024 (galE), and GR026 (BMEI1090-BMEI1091) confer protection in mice
    Gireesh Rajashekara
    Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI 53706, USA
    Infect Immun 74:2925-36. 2006
    ....
  18. ncbi Comparative whole-genome hybridization reveals genomic islands in Brucella species
    Gireesh Rajashekara
    Department of Animal Health and Biomedical Sciences, University of Wisconsin, 1656 Linden Dr, Madison, WI 53706, USA
    J Bacteriol 186:5040-51. 2004
    ....
  19. ncbi CGHScan: finding variable regions using high-density microarray comparative genomic hybridization data
    Bradley D Anderson
    Animal Health and Biomedical Sciences, University of Wisconsin, Madison, WI 53706, USA
    BMC Genomics 7:91. 2006
    ..Many of these methods are ill suited for datasets with the number of measurements typical of high-density microarrays...