Petko M Petkov

Summary

Affiliation: The Jackson Laboratory
Country: USA

Publications

  1. ncbi Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse
    Petko M Petkov
    The Jackson Laboratory, Technology Development, Bar Harbor, ME 04609, USA
    Genomics 83:902-11. 2004
  2. ncbi Crossover interference underlies sex differences in recombination rates
    Petko M Petkov
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Trends Genet 23:539-42. 2007
  3. ncbi An efficient SNP system for mouse genome scanning and elucidating strain relationships
    Petko M Petkov
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genome Res 14:1806-11. 2004
  4. ncbi Evidence of a large-scale functional organization of mammalian chromosomes
    Petko M Petkov
    The Jackson Laboratory, Bar Harbor, Maine, USA
    PLoS Genet 1:e33. 2005
  5. ncbi Evidence of a large-scale functional organization of Mammalian chromosomes
    Petko M Petkov
    PLoS Biol 5:e127; author reply e128. 2007
  6. ncbi Trans-regulation of mouse meiotic recombination hotspots by Rcr1
    Emil D Parvanov
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, Maine, USA
    PLoS Biol 7:e36. 2009
  7. ncbi Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine, USA
    BMC Mol Biol 10:43. 2009
  8. ncbi Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping
    Timothy Billings
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, Maine, United States of America
    PLoS ONE 5:e15340. 2010
  9. ncbi Prdm9 controls activation of mammalian recombination hotspots
    Emil D Parvanov
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Science 327:835. 2010
  10. ncbi A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genomics 92:204-9. 2008

Research Grants

  1. Chromosome-Wide Mapping of Recombinational Activity
    Petko M Petkov; Fiscal Year: 2010
  2. Chromosome-Wide Mapping of Recombinational Activity
    Petko Petkov; Fiscal Year: 2009

Collaborators

Detail Information

Publications13

  1. ncbi Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse
    Petko M Petkov
    The Jackson Laboratory, Technology Development, Bar Harbor, ME 04609, USA
    Genomics 83:902-11. 2004
    ....
  2. ncbi Crossover interference underlies sex differences in recombination rates
    Petko M Petkov
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Trends Genet 23:539-42. 2007
    ..However, the interference distance is the same in terms of bivalent length. We propose a model in which the interference distance in the two sexes reflects the compaction of chromosomes at the pachytene stage of meiosis...
  3. ncbi An efficient SNP system for mouse genome scanning and elucidating strain relationships
    Petko M Petkov
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genome Res 14:1806-11. 2004
    ..Applying a neighbor-joining method to the data, we constructed a mouse strain family tree, which in most cases confirmed existing genealogies...
  4. ncbi Evidence of a large-scale functional organization of mammalian chromosomes
    Petko M Petkov
    The Jackson Laboratory, Bar Harbor, Maine, USA
    PLoS Genet 1:e33. 2005
    ..Given the strong conservation of gene order among mammals, the domains and networks we find in mice probably characterize all mammals, including humans...
  5. ncbi Evidence of a large-scale functional organization of Mammalian chromosomes
    Petko M Petkov
    PLoS Biol 5:e127; author reply e128. 2007
  6. ncbi Trans-regulation of mouse meiotic recombination hotspots by Rcr1
    Emil D Parvanov
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, Maine, USA
    PLoS Biol 7:e36. 2009
    ....
  7. ncbi Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine, USA
    BMC Mol Biol 10:43. 2009
    ....
  8. ncbi Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping
    Timothy Billings
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, Maine, United States of America
    PLoS ONE 5:e15340. 2010
    ..It appears that mammalian recombination is regulated on at least three levels, chromosome-wide, regional, and at individual hotspots, and these regulation levels are influenced by sex and genetic background but not by gene content...
  9. ncbi Prdm9 controls activation of mammalian recombination hotspots
    Emil D Parvanov
    The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Science 327:835. 2010
    ..The identification of Prdm9 as a protein regulating mammalian recombination hotspots initiates molecular studies of this important biological control system...
  10. ncbi A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genomics 92:204-9. 2008
    ..Using this technique, we analyzed recombination events at the Hlx1 hotspot located on mouse chromosome 1, finding that the results agree well with a prior genetic characterization of 3026 male and 3002 female meioses...
  11. ncbi Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genes Chromosomes Cancer 48:925-30. 2009
    ..It is likely that some regions of the genome are more susceptible to both somatic and meiotic DSBs, and the locations of meiotic hotspots may be an indicator of genomic regions more susceptible to DNA damage...
  12. ncbi The recombinational anatomy of a mouse chromosome
    Kenneth Paigen
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, Maine, United States of America
    PLoS Genet 4:e1000119. 2008
    ..It appears that the regulation of mammalian recombination is a complex, dynamic process involving multiple factors reflecting species, sex, individual variation within species, and the properties of individual hotspots...
  13. ncbi Patterns and mechanisms of genome organization in the mouse
    Joel H Graber
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    J Exp Zoolog A Comp Exp Biol 305:683-8. 2006
    ..The strong conservation of gene order among mammals suggests that the domains and networks we find likely characterize all mammals, and possibly beyond...

Research Grants5

  1. Chromosome-Wide Mapping of Recombinational Activity
    Petko M Petkov; Fiscal Year: 2010
    ....
  2. Chromosome-Wide Mapping of Recombinational Activity
    Petko Petkov; Fiscal Year: 2009
    ....