Siemon H Ng

Summary

Affiliation: The Jackson Laboratory
Country: USA

Publications

  1. ncbi Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine, USA
    BMC Mol Biol 10:43. 2009
  2. ncbi A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genomics 92:204-9. 2008
  3. ncbi Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genes Chromosomes Cancer 48:925-30. 2009

Detail Information

Publications3

  1. ncbi Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine, USA
    BMC Mol Biol 10:43. 2009
    ....
  2. ncbi A quantitative assay for crossover and noncrossover molecular events at individual recombination hotspots in both male and female gametes
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genomics 92:204-9. 2008
    ..Using this technique, we analyzed recombination events at the Hlx1 hotspot located on mouse chromosome 1, finding that the results agree well with a prior genetic characterization of 3026 male and 3002 female meioses...
  3. ncbi Colocalization of somatic and meiotic double strand breaks near the Myc oncogene on mouse chromosome 15
    Siemon H Ng
    Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, USA
    Genes Chromosomes Cancer 48:925-30. 2009
    ..It is likely that some regions of the genome are more susceptible to both somatic and meiotic DSBs, and the locations of meiotic hotspots may be an indicator of genomic regions more susceptible to DNA damage...