Research Topics
| Carl MorrisonSummaryAffiliation: The Ohio State University Country: USA Publications
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Detail Information
Publications
Molecular classification of parathyroid neoplasia by gene expression profilingCarl Morrison
Department of Anatomic Pathology, The Ohio State University, 310 West 10th Ave, M 417 Starling Loving Hall, Columbus, OH 43210, USA
Am J Pathol 165:565-76. 2004....- MYC amplification and polysomy 8 in chondrosarcoma: array comparative genomic hybridization, fluorescent in situ hybridization, and association with outcomeCarl Morrison
Division of Orthopedic Oncology, Department of Pathology, Center for Biostatistics, The Arthur James Cancer Hospital and Richard Solove Research Institute, The Ohio State University Medical School, Columbus, OH, USA
J Clin Oncol 23:9369-76. 2005..To identify recurrent regions of genomic gain or loss in chondrosarcoma in a clinically relevant and statistically valid fashion. Materials and.. - 20q11.1 amplification in giant-cell tumor of bone: Array CGH, FISH, and association with outcomeLaura T Smith
Division of Human Cancer Genetics, Department of Molecular Virology, Immunology and Medical Genetics, Arthur James Cancer Hospital and Richard Solove Research Institute, The Ohio State University, Columbus, OH, USA
Genes Chromosomes Cancer 45:957-66. 2006..001) was the only factor to reach statistical significance. 20q11.1 amplification can be used as a marker of prognostic importance in GCTb. We propose TPX2 as a candidate oncogene in the core-amplified region at 20q11.1... - HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patientsCarl Morrison
Department of Pathology, Division of Gynecologic Oncology Center for Biostatistics, The Arthur James Cancer Hospital, and the Richard Solove Research Institute, The Ohio State University Medical School Columbus, OH 43210, USA
J Clin Oncol 24:2376-85. 2006..To evaluate HER-2 expression and amplification in a large cohort of endometrial cancer with complete surgical staging and outcome data... - The mucin expression profile of endometrial carcinoma and correlation with clinical-pathologic parametersCarl Morrison
Department of Pathology, Center for Biostatistics, The Ohio State University, Columbus, OH, USA
Appl Immunohistochem Mol Morphol 15:426-31. 2007..0% vs. 39/52, 75.0%, P=0.01). No significant differences in any of the mucins were noted among the other end points evaluated. Mucin expression did not correlate with tumor grade, stage, or patient outcome... - Fine-needle aspiration biopsy of non-Hodgkin lymphoma for use in expression microarray analysisCarl Morrison
Department of Pathology, The Arthur James Cancer Hospital and Richard Solove Research Institute, The Ohio State University Medical School, Columbus, Ohio, USA
Cancer 108:311-8. 2006..Fine-needle aspiration (FNA) biopsy is a minimally invasive procedure, and acquiring routine posttreatment material would require minimal effort and provide needed material for gene expression profiling... - FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogeneTao Zuo
Program in Molecular, Cellular, and Developmental Biology and Department of Molecular Virology, Immunology, and Medical Genetics, Ohio State University Medical Center and Comprehensive Cancer Center, Columbus, OH 43210, USA
Cell 129:1275-86. 2007..Our data demonstrate that FOXP3 is an X-linked breast cancer suppressor gene and an important regulator of the HER-2/ErbB2 oncogene... - A GOG 210 aCGH study of gain at 1q23 in endometrioid endometrial cancer in the context of racial disparity and outcomeCarl Morrison
Division of Molecular Pathology, Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Genes Chromosomes Cancer 49:791-802. 2010..Univariate analyses for gain at 1q23 showed a significant association (P = 0.009) with survival. Multivariate analysis for gain at 1q23 did not show a significant association with survival (P = 0.14)... - Assessment of TCR-beta clonality in a diverse group of cutaneous T-Cell infiltratesJose Antonio Plaza
Department of Pathology, MD Anderson, Houston, USA
J Cutan Pathol 35:358-65. 2008..e. PLC, PPD and atypical lymphocytic lobular panniculitis) could manifest restricted molecular profiles in the context of an oligoclonal process or frank monoclonality... - CDX2 is a useful marker of intestinal-type differentiation: a tissue microarray-based study of 629 tumors from various sitesLindsey B De Lott
Department of Pathology, The Ohio State University Medical Center, Columbus, OH, USA
Arch Pathol Lab Med 129:1100-5. 2005..However, CDX2 is not a sensitive marker for poorly differentiated colorectal carcinoma... - Correlation of cyclooxygenase-2 (COX-2) and aromatase expression in human endometrial cancer: tissue microarray analysisJeffrey M Fowler
Division of Gynecologic Oncology, The Ohio State University Medical School, Columbus, OH 43210, USA
Am J Obstet Gynecol 192:1262-71; discussion 1271-3. 2005.... - Breast carcinoma with amplified HER2: a gene expression signature specific for trastuzumab resistance and poor prognosisThaer Khoury
Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Mod Pathol 23:1364-78. 2010.... - CD8+ lymphomatoid papulosis and its differential diagnosisCynthia M Magro
Department of Pathology, Ohio State University, Columbus 43210, USA
Am J Clin Pathol 125:490-501. 2006..CD30 expression can occur in other forms of CD8 lymphoproliferative disease unrelated to primary cutaneous anaplastic large cell lymphoma or LyP... - Talar osteosarcoma in an elderly womanBradley S Ellison
Department of Orthopedic Surgery, Ohio State University Medical Center, Columbus, OH 43210, USA
Am J Orthop 37:198-203. 2008 - Fluorescent in situ hybridization and array comparative genomic hybridization: complementary techniques for genomic evaluationCarl Morrison
The Pathology Core Facility, Arthur James Cancer Hospital and Richard Solove Research Institute, The Ohio State University Medical School, Columbus 43210, USA
Arch Pathol Lab Med 130:967-74. 2006..A thorough understanding of this technology will be useful for all surgical pathologists in the near future, as this technology will no doubt have some influence on our daily practice... - Metastases to soft tissue: a review of 118 cases over a 30-year periodJose Antonio Plaza
Division of Anatomic Pathology, Department of Pathology, Ohio State University Medical Center and Arthur G James Comprehensive Cancer Center, Columbus, Ohio, USA
Cancer 112:193-203. 2008..The authors' experience was reviewed at a large academic medical center over a 30-year period (1971-2000) with metastases to soft tissue... - Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancerRomulo M Brena
Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
PLoS Med 4:e108. 2007..However, the overall survival of patients with resectable tumors varies significantly, indicating the need for additional prognostic factors to better predict the outcome of the disease, particularly within a given TNM subset... - The utility of estrogen receptor and progesterone receptor immunohistochemistry in the distinction of metastatic breast carcinoma from other tumors in the liverJason W Nash
Department of Pathology, The Ohio State University, Columbus, USA
Arch Pathol Lab Med 127:1591-5. 2003..Therefore, ER and PR staining have limited utility in the distinction of MBA from HCC, CC, and other metastatic adenocarcinomas in the liver... - Peroxisome proliferator-activated receptor gamma is frequently downregulated in a diversity of sporadic nonmedullary thyroid carcinomasMicheala A Aldred
Human Cancer Genetics Program, The Ohio State University, Columbus, OH, USA
Oncogene 22:3412-6. 2003.... - Cystic schwannoma of the pancreasGuangming Tan
Departments of Pathology and Radiology, The Ohio State University Medical Center, Columbus, OH 43210, USA
Ann Diagn Pathol 7:285-91. 2003..Cystic schwannoma is a rare neoplasm occurring in the pancreas and should be considered in the differential diagnoses for patients presenting with pancreatic cystic lesions... - Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assayMichael Chen
College of Medicine and Public Health, Ohio State University, Columbus, Ohio, USA
Appl Immunohistochem Mol Morphol 12:373-9. 2004..Although LCM appears to improve the sensitivity for detecting preneoplastic conditions, the relative specificity appears to be the same as that encountered with routine SSCP... - Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cellsEric V Yang
Department of Molecular Virology, The Ohio State University Medical Center, Columbus, OH 43210, USA
Cancer Res 66:10357-64. 2006..The data suggest that catecholamine hormones produced by the sympathetic-adrenal medullary axis may affect NPC tumor progression, in part, through modulation of key angiogenic cytokines... - HER2 testing: how to reach a high concordance rate between immunohistochemistry and fluorescence in situ hybridizationThaer Khoury
Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Appl Immunohistochem Mol Morphol 19:424-30. 2011..The concordance rate between immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) for human epidermal growth factor receptor-2 (HER2) is still a major clinical concern. We describe a new criteria evaluating HER2 IHC... - A comparison of CD10 to pCEA, MOC-31, and hepatocyte for the distinction of malignant tumors in the liverCarl Morrison
Department of Pathology, The Ohio State University, College of Medicine, Columbus, Ohio, USA
Mod Pathol 15:1279-87. 2002..The combination of Hepatocyte, MOC31, and pCEA correctly classified 99 of 100 tumors in this study and is our proposed panel of immunostains for the initial workup of malignant tumors in the liver... - Chromosome 11 genomic changes in parathyroid adenoma and hyperplasia: array CGH, FISH, and tissue microarraysY Yi
Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
Genes Chromosomes Cancer 47:639-48. 2008..This genetic change was relatively independent of other chromosome 11 changes and present in slightly less than one-half of adenomas. 11q23 deletion along with relatively strong CCND1 expression was common in uremic hyperparathyroidism... - Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203Martin J Edelman
University of Maryland Greenebaum Cancer Center, Division of Hematology Oncology 111H, 22 South Greene Street, Baltimore, MD 21201 1595, USA
J Clin Oncol 26:848-55. 2008.... - A gene expression signature predicts survival of patients with stage I non-small cell lung cancerYan Lu
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America
PLoS Med 3:e467. 2006..CONCLUSIONS: Our results indicate that gene expression signatures from several datasets can be reconciled. The resulting signature is useful in predicting survival of stage I NSCLC and might be useful in informing treatment decisions... - Overexpression of folate binding protein and mesothelin are associated with uterine serous carcinomaLouis A Dainty
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and the United States Military Cancer Institute, Walter Reed Army Medical Center, Washington, DC 20307, USA
Gynecol Oncol 105:563-70. 2007..The purpose of this study was to examine the expression of FOLR1 in uterine cancers and to identify changes in gene expression that are associated with overexpression of FOLR1... - Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancerWenrui Duan
Comprehensive Cancer Center and Department of Internal Medicine, The Ohio State University College of Medicine and Public Health, Columbus 43210 1240, USA
J Natl Cancer Inst 96:1718-21. 2004..These results are consistent with the hypothesis that increased Pirh2 expression affects lung tumorigenesis by reducing p53 activity. To our knowledge, this is the first description of altered Pirh2 expression in human and mouse tumors... - Overexpression of folate binding protein is associated with shortened progression-free survival in uterine adenocarcinomasJay E Allard
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and the United States Military Cancer Institute, Walter Reed Army Medical Center, Washington, DC, USA
Gynecol Oncol 107:52-7. 2007..Since FOLR1 overexpression is a frequent event in some types of endometrial carcinoma, we examined the relationship between FOLR1 overexpression and clinical and pathologic features to determine its prognostic relevance... - Loss of parafibromin immunoreactivity is a distinguishing feature of parathyroid carcinomaMin-Han Tan
Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA
Clin Cancer Res 10:6629-37. 2004..The similar loss of parafibromin immunoreactivity in HPT-JT syndrome-related adenomas suggests that this is a pivotal step in parathyroid tumorigenesis...