IAN JOHN MACRAESummaryAffiliation: The Scripps Research Institute Country: USA PublicationsResearch Grants
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Detail Information
Publications
In vitro reconstitution of the human RISC-loading complexIan J Macrae
Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 105:512-7. 2008..Furthermore, once Ago2 is loaded with an miRNA, it tends to dissociate from the rest of the complex. These results lay the groundwork for future structural and functional dissection of RISC loading in humans...
Research Grants
- Structure and Mechanism of the RISC-loading ComplexIAN JOHN MACRAE; Fiscal Year: 2010..Results will contribute to on-going efforts to harness the RNAi process as a powerful new type of therapeutic for the treatment of human disease. ..
- Structure and Mechanism of the RISC-loading ComplexIAN MACRAE; Fiscal Year: 2009..Results will contribute to on-going efforts to harness the RNAi process as a powerful new type of therapeutic for the treatment of human disease. ..
- Structure and Mechanism of the RISC-loading ComplexIAN JOHN MACRAE; Fiscal Year: 2011..Results will contribute to on-going efforts to harness the RNAi process as a powerful new type of therapeutic for the treatment of human disease. ..
