Research Topics
| Guang Hui LiuSummaryAffiliation: The Scripps Research Institute Country: USA Publications
| Collaborators |
Detail Information
Publications
Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cellsGuang Hui Liu
Department of Cell Biology, The Scripps Research Institute, La Jolla, California, USA
PLoS ONE 4:e7031. 2009....
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndromeGuang Hui Liu
Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
Nature 472:221-5. 2011..Because progerin also accumulates during physiological ageing, our results provide an in vitro iPSC-based model to study the pathogenesis of human premature and physiological vascular ageing...
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCsGuang Hui Liu
Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
Cell Stem Cell 8:688-94. 2011..This type of approach could be used to generate genotype-matched cell lines for disease modeling and drug discovery and potentially also in therapeutics...
Regulation of myoblast differentiation by the nuclear envelope protein NET39Guang Hui Liu
Department of Cell Biology, IMM 10, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Mol Cell Biol 29:5800-12. 2009..Our results indicate that NET39 is part of the regulatory machinery for myogenesis and raise the possibility that it may be important for muscle homeostasis...
