Research Topics
Species | Ruth L KatzSummaryAffiliation: The University of Texas Country: USA Publications
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Publications
Automated detection of genetic abnormalities combined with cytology in sputum is a sensitive predictor of lung cancerRuth L Katz
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
Mod Pathol 21:950-60. 2008..For diagnosing lung cancer in sputum, a combination of molecular and cytologic variables was superior to using conventional cytology alone...
Genetically abnormal circulating cells in lung cancer patients: an antigen-independent fluorescence in situ hybridization-based case-control studyRuth L Katz
Department of Pathology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Clin Cancer Res 16:3976-87. 2010....
Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancerFeng Jiang
Department of Pathology, Greenbaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 1192, USA
Mol Cancer Res 7:330-8. 2009..These findings offer an important new tool for the study of lung CSCs and provide a potential prognostic factor and therapeutic target for treatment of the patients with lung cancer...
Surfactant protein A gene deletion and prognostics for patients with stage I non-small cell lung cancerFeng Jiang
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 11:5417-24. 2005..The present study was conducted to determine clinical relevance of surfactant protein A (SP-A) genetic aberrations in early-stage non-small cell lung cancer (NSCLC)...
Combined genetic analysis of sputum and computed tomography for noninvasive diagnosis of non-small-cell lung cancerFeng Jiang
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201 1192, USA
Lung Cancer 66:58-63. 2009..05). The integration of the genetic assay with CT led to improvements in noninvasive diagnosis of stage I NSCLCs, especially central tumors...
Centrosomal abnormality is common in and a potential biomarker for bladder cancerFeng Jiang
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
Int J Cancer 106:661-5. 2003..Centrosomal abnormalities appear to be intrinsic to aneuploidy and tumorigenesis and may be potential markers for early detection of bladder cancer...
Quantitation of Aurora kinase A gene copy number in urine sediments and bladder cancer detectionHong Seok Park
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Natl Cancer Inst 100:1401-11. 2008..We examined whether AURKA gene amplification is a biomarker for the detection of bladder cancer...
Chromosomal abnormalities detected by multicolor fluorescence in situ hybridization in fine-needle aspirates from patients with small lymphocytic lymphoma are useful for predicting survivalNancy P Caraway
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 114:315-22. 2008....
Early detection of lung adenocarcinoma in sputum by a panel of microRNA markersLei Yu
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201 1192, USA
Int J Cancer 127:2870-8. 2010..The sputum markers demonstrated the potential of translation to laboratory settings for improving the early detection of lung adenocarcinoma...
Magnetic enrichment of bronchial epithelial cells from sputum for lung cancer diagnosisQi Qiu
Department of Pathology, University of Maryland School of Medicine, 10 South Pine St, MSTF 7th Fl, Baltimore, MD 21201 1192, USA
Cancer 114:275-83. 2008..We propose to obtain concentrated and purified bronchial epithelial cells to improve early detection of lung cancer in sputum samples...
Evaluation of peripheral blood involvement of mantle cell lymphoma by fluorescence in situ hybridization in comparison with immunophenotypic and morphologic findingsJun Gu
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Mod Pathol 17:553-60. 2004....
Overexpression of S100A2 protein as a prognostic marker for patients with stage I non small cell lung cancerHuijun Wang
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
Int J Cancer 116:285-90. 2005..Our results suggested that the expression of the S100A2 protein in stage I NSCLC indicates poor prognosis and may be used to identify patients with early-stage NSCLC who might benefit from adjuvant treatment...
Fluorescence in situ hybridization for detecting urothelial carcinoma: a clinicopathologic studyNancy P Caraway
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Cancer Cytopathol 118:259-68. 2010..Fluorescence in situ hybridization (FISH) has been shown to be more sensitive than cytology in the detection of UC. The current study evaluated the use of FISH for detecting UC...
Genomic profiles in stage I primary non small cell lung cancer using comparative genomic hybridization analysis of cDNA microarraysFeng Jiang
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
Neoplasia 6:623-35. 2004..The identified genomic aberrations may be involved in the initiation and progression of lung tumorigenesis and, most importantly, may be developed as new biomarkers for the early detection and classification of lung cancer...
Activating enhancer-binding protein-2? nucleolar localization predicts poor survival after stage I non-small cell lung cancer resectionMin P Kim
Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Ann Thorac Surg 92:1044-50. 2011....
Plasma microRNAs as potential biomarkers for non-small-cell lung cancerJun Shen
Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201 1192, USA
Lab Invest 91:579-87. 2011..67%) in diagnosis of lung adenocarcinomas compared with squamous cell carcinomas (82.35%) (P<0.05). Altered expressions of the miRNAs in plasma would provide potential blood-based biomarkers for NSCLC...
RNA silencing of S-phase kinase-interacting protein 2 inhibits proliferation and centrosome amplification in lung cancer cellsFeng Jiang
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Oncogene 24:3409-18. 2005..These results imply that SKP2 plays an oncogenic role in lung cancer and that SKP2 silencing may be useful in the treatment of lung cancer...
Use of fluorescence in situ hybridization to predict response to bacillus Calmette-Guérin therapy for bladder cancer: results of a prospective trialAshish M Kamat
Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
J Urol 187:862-7. 2012..We initiated a prospective clinical trial to determine whether fluorescence in situ hybridization results during bacillus Calmette-Guérin immunotherapy can predict therapy failure...
Gain of the 3q26 region in cervicovaginal liquid-based pap preparations is associated with squamous intraepithelial lesions and squamous cell carcinomaNancy P Caraway
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Gynecol Oncol 110:37-42. 2008..In this study, cervicovaginal specimens were analyzed by fluorescence in situ hybridization (FISH) for gain of chromosome 3q26 containing hTERC, and FISH findings were compared with the cytologic and histologic diagnoses...
Up-regulation of 14-3-3zeta in lung cancer and its implication as prognostic and therapeutic targetTao Fan
Department of Pathology, University of Maryland Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 1192, USA
Cancer Res 67:7901-6. 2007..008). Our results suggest that 14-3-3zeta is a potential target for developing a prognostic biomarker and therapeutics that can enhance the antitumor activity of cisplatin for NSCLC...
Grading follicular lymphoma on fine needle aspiration specimens. Comparison with proliferative index by DNA image analysis and Ki-67 labeling indexWei Sun
Division of Pathology and Laboratory Medicine, Department of Pathology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 053, Houston, Texas 77030, USA
Acta Cytol 48:119-26. 2004..PI by DIA and Ki-67 LI clearly distinguished FL grade 1 from FL grades 2 and 3; however, it did not clearly distinguish between grades 2 and 3...
Evaluation of interphase fluorescence in situ hybridization for the t(14;18)(q32;q21) translocation in the diagnosis of follicular lymphoma on fine-needle aspirates: a comparison with flow cytometry immunophenotypingYun Gong
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 99:385-93. 2003..For detecting a follicle center cell origin in DLBCLs, I-FISH for the t(14;18) translocation appeared to be slightly more sensitive than FCM for the CD19+/CD10+ immunophenotype...
Combination of cytologic evaluation and quantitative digital cytometry is reliable in detecting recurrent disease in patients with urinary diversionsNancy P Caraway
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 111:323-9. 2007..In this retrospective study, the reliability of quantitative digital cytometry (QDC) in conjunction with cytologic evaluation in detecting recurrent disease was determined in these patients...
A review on the current state of urine cytology emphasizing the role of fluorescence in situ hybridization as an adjunct to diagnosisNancy P Caraway
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer Cytopathol 118:175-83. 2010....
Phase III prevention trial of fenretinide in patients with resected non-muscle-invasive bladder cancerAnita L Sabichi
Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
Clin Cancer Res 14:224-9. 2008..The study aims to evaluate the efficacy and toxicity of fenretinide in preventing tumor recurrence in patients with transitional cell carcinoma (TCC) of the bladder...
Fine-needle aspiration biopsy findings in patients with small lymphocytic lymphoma transformed to hodgkin lymphomaF Catrina Reading
Departments of Pathology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Am J Clin Pathol 128:571-8. 2007..In these cases, histologic confirmation is always recommended, not only to differentiate HL transformation from other entities but also for subclassification of HL...
PTEN genomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancerKanishka Sircar
The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, TX, USA
J Pathol 218:505-13. 2009..0001), AR (p = 0.025), and to cancer-specific mortality (p = 0.039). PTEN deletion is common in HRPC, with bi-allelic loss correlating to disease-specific mortality and associated with Akt and AR deregulation...
Detection of a subset of CD30+ anaplastic large cell lymphoma by interphase fluorescence in situ hybridizationHyung Ju C Shin
Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Diagn Cytopathol 29:61-6. 2003..Using a commercially available probe, detection of ALK breakpoints in the FNA specimens is simple and can be a useful diagnostic adjunct in cases where distinction from other lymphomas or lymphoid lesions is morphologically difficult...
Rapid detection of IgH/BCL2 rearrangement in follicular lymphoma by interphase fluorescence in situ hybridization with bacterial artificial chromosome probesFeng Jiang
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA
J Mol Diagn 4:144-9. 2002..These results were confirmed with fiber FISH assays on the same specimens. This interphase FISH assay is rapid and reliable for detecting rearrangements in the IGH/BCL2 gene, thereby aiding in the diagnosis of FL on FNA biopsy specimens...
Nonablative allogeneic stem-cell transplantation for advanced/recurrent mantle-cell lymphomaIssa F Khouri
Department of Blood and Marrow Transplantation, Unit 423, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Clin Oncol 21:4407-12. 2003..Patients with relapsed mantle-cell lymphoma have poor prognosis and short survival. Our aim was to determine the efficacy of nonablative allogeneic stem-cell transplantation in patients with relapsed mantle-cell lymphoma...
Cytomorphologic spectrum of small lymphocytic lymphoma in patients with an accelerated clinical courseHyung Ju C Shin
Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Cancer 99:293-300. 2003..The objective of this study was to evaluate reliable criteria for recognizing SLL-AP and SLL in transformation that are needed to determine the appropriate clinical management of individual patients...
Cytologic features of renal medullary carcinomaLina Assad
Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 105:28-34. 2005..The clinical findings are key to diagnosing renal medullary carcinoma...
Expression and relevance of TRPS-1: a new GATA transcription factor in breast cancerJie Qing Chen
Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
Horm Cancer 2:132-43. 2011..This model predicts that BCs with low or no TRPS-1 expression may inherently be much less differentiated and more aggressive tumors with less favorable prognosis...
High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabineJorge E Romaguera
Department of Lymphoma, Unit 429, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 23:7013-23. 2005..To determine the response, failure-free survival (FFS), and overall survival rates and toxicity of rituximab plus an intense chemotherapy regimen in patients with previously untreated aggressive mantle-cell lymphoma (MCL)...
Prospective isolation of clonogenic mantle cell lymphoma-initiating cellsZheng Chen
Centre for Stem Cell Research, Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases IMM, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Stem Cell Res 5:212-25. 2010....
Expression of PAX5 in CD20-positive multiple myeloma assessed by immunohistochemistry and oligonucleotide microarrayPei Lin
Department of Pathology, University of Arkansas for Medical Science, USA
Mod Pathol 17:1217-22. 2004..We conclude that CD20-positive myelomas expressing PAX5/BSAP can present as a diagnostic pitfall mimicking B-cell neoplasms with plasmacytoid differentiation...
Use of interphase fluorescence in situ hybridization as a powerful diagnostic tool in cytologyFeng Jiang
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA
Diagn Mol Pathol 11:47-57. 2002..Here, we outline the principle of the I-FISH procedure, present suggestions to efficiently analyze cytologic materials, provide examples of practical applications, and discuss new aspects of the technique...
Comparison of quantification of histochemical staining by hue-saturation-intensity (HSI) transformation and color-deconvolutionArnout C Ruifrok
Department of Pathology, Box 53, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Appl Immunohistochem Mol Morphol 11:85-91. 2003..This resulted in significant increase in sensitivity of classification of samples with increased KI-67 labeling without changing the specificity, when compared to the HSI based method...
Low grade astrocytoma presenting with visual lossMorris D Groves
The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
J Neurooncol 89:49-50. 2008
Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cellsMartin Korbling
Departments of Blood and Marrow Transplantation, University of Texas M D Anderson Cancer Center, Houston 77030, USA
N Engl J Med 346:738-46. 2002..Bone marrow contains stem cells with the potential to differentiate into mature cells of various organs. We determined whether circulating stem cells have a similar potential...
Case 69: extramedullary hematopoiesisHaesun Choi
Divisions of Diagnostic Imaging and Pathology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, PO Box 57, Houston, TX 77030, USA
Radiology 231:52-6. 2004
