Research Topics
| Sharon H GiordanoSummaryAffiliation: The University of Texas Country: USA Publications
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Publications
Survival advantage in Medicare patients receiving drug-eluting stents compared with bare metal stents: real or artefactual?Fen Wei Wang
Division of Cardiology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA
Catheter Cardiovasc Interv 71:636-43. 2008..We evaluated mortality in the first year after implantation of DES, specifically the sirolimus-eluting stent (SES), Cypher vs. BMS in "real world" older patients using the Medicare claims database...- Adjuvant systemic therapy for male breast carcinomaSharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 104:2359-64. 2005..In the current study, the authors describe the M. D. Anderson experience with adjuvant systemic therapy in male breast carcinoma patients... - Limits of observational data in determining outcomes from cancer therapySharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Cancer 112:2456-66. 2008..Observational data are used increasingly to assess the effectiveness of therapies. However, selection biases are likely to have an impact on results and threaten the validity of these studies... - Use and outcomes of adjuvant chemotherapy in older women with breast cancerSharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77230, USA
J Clin Oncol 24:2750-6. 2006..This study was undertaken to determine patterns and outcomes of adjuvant chemotherapy use in a population-based cohort of older women with primary breast cancer... - Late gastrointestinal toxicity after radiation for prostate cancerSharon H Giordano
Department of Breast Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 107:423-32. 2006..The current study was designed to determine rates and predictors of late, lower gastrointestinal toxicity after radiation therapy in a population-based cohort of older men with prostate cancer... - Use of intravenous bisphosphonates in older women with breast cancerSharon H Giordano
Department of Breast Medical Oncology, The University of Texas, Houston, Texas 77030, USA
Oncologist 13:494-502. 2008..i.v. bisphosphonates reduce skeletal events in women with bone metastases from breast cancer, but little is known about the prevalence and duration of bisphosphonate use... - Impact of a scientific presentation on community treatment patterns for primary breast cancerSharon H Giordano
Department of Breast Medical Oncology, University of Texas M D Anderson Cancer Center, Box 424, Houston, TX 77030, USA
J Natl Cancer Inst 98:382-8. 2006.... - A review of the diagnosis and management of male breast cancerSharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 424, Houston, Texas 77030, USA
Oncologist 10:471-9. 2005..It shares many similarities with breast cancer in women; yet some clear differences have emerged. In this article, the latest information on the epidemiology, biology, and treatment of male breast cancer is reviewed... - Risk of cardiac death after adjuvant radiotherapy for breast cancerSharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe, Box 424, Houston, TX 77030, USA
J Natl Cancer Inst 97:419-24. 2005..Because radiation techniques have improved over time, we investigated whether the risk of death from ischemic heart disease after adjuvant breast radiotherapy decreased over time... - Breast cancer treatment guidelines in older womenSharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 23:783-91. 2005..To determine patterns and predictors of concordance with institutional treatment guidelines among older women with breast cancer... - Update on locally advanced breast cancerSharon H Giordano
University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Oncologist 8:521-30. 2003..Inflammatory cancer is also reviewed, but is considered separately due to its distinct biology and clinical behavior... - Breast carcinoma in men: a population-based studySharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, PO Box 424, Houston, TX 77030, USA
Cancer 101:51-7. 2004.... - Inflammatory breast cancer: clinical progress and the main problems that must be addressedSharon H Giordano
Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Breast Cancer Res 5:284-8. 2003..This article reviews the clinical characteristics of inflammatory breast cancer and the recent advances in therapy... - Is breast cancer survival improving?Sharon H Giordano
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 100:44-52. 2004..The objective of the current study was to determine whether the survival of women with recurrent breast cancer has improved from 1974 to 2000... - Radiation use and long-term survival in breast cancer patients with T1, T2 primary tumors and one to three positive axillary lymph nodesThomas A Buchholz
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 71:1022-7. 2008..For patients with Stage II breast cancer with one to three positive lymph nodes, controversy exists about whether radiation as a component of treatment provides a survival benefit... - Triple receptor-negative breast cancer: the effect of race on response to primary systemic treatment and survival outcomesShaheenah Dawood
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
J Clin Oncol 27:220-6. 2009..The goal of this study was to describe the effect of race on pathologic complete response (pCR) rates and survival outcomes in women with triple receptor-negative (TN) breast cancers... - Breast-conserving surgery in older patients with invasive breast cancer: current patterns of treatment across the United StatesGrace L Smith
Department of Radiation Oncology, The Section of Health Services Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Am Coll Surg 209:425-433.e2. 2009..But earlier studies report low BCS use rates of 12% to 43% nationally, especially in older patients. We sought to determine current patterns and predictors of BCS use... - Association between treatment with brachytherapy vs whole-breast irradiation and subsequent mastectomy, complications, and survival among older women with invasive breast cancerGrace L Smith
Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
JAMA 307:1827-37. 2012..Because results of long-term randomized trials will not be reported for years, detailed analysis of clinical outcomes in a nonrandomized setting is warranted... - Racial disparities in the use of radiotherapy after breast-conserving surgery: a national Medicare studyGrace L Smith
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 116:734-41. 2010..Therefore, in a comprehensive, national cohort of Medicare patients, racial disparities in the use of radiotherapy (RT) after breast-conserving surgery (BCS) for invasive breast cancer were quantified... - Risk of hypothyroidism in older breast cancer patients treated with radiationGrace L Smith
Department of Breast Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 112:1371-9. 2008..The authors assessed risk of hypothyroidism in breast cancer patients who were receiving RT to a supraclavicular field, which typically includes a portion of thyroid... - Cerebrovascular disease risk in older head and neck cancer patients after radiotherapyGrace L Smith
Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 26:5119-25. 2008..Cerebrovascular disease is common in head and neck cancer patients, but it is unknown whether radiotherapy increases the cerebrovascular disease risk in this population... - Adoption of intensity-modulated radiation therapy for breast cancer in the United StatesBenjamin D Smith
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1202, Houston, TX 77030, USA
J Natl Cancer Inst 103:798-809. 2011..It is thus controversial whether such treatment justifies billing for intensity-modulated radiation therapy (IMRT)... - Mammography capacity impact on screening rates and breast cancer stage at diagnosisLinda S Elting
Section of Health Services Research, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Am J Prev Med 37:102-8. 2009..S. reportedly is adequate, but has not been examined in nonmetropolitan areas. This study examined the relationships between in-county mammography facilities and rates of mammography screening and late-stage diagnosis of breast cancers... - Mammography before diagnosis among women age 80 years and older with breast cancerBrian D Badgwell
Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, 1400 Holcombe Blvd, PO Box 301402, Houston, TX 77030 1402, USA
J Clin Oncol 26:2482-8. 2008..Screening mammography guidelines for patients age 80 years and older are variable. We determined the effect of mammography use on stage at breast cancer diagnosis and survival among women of this age range... - Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based reviewShaheenah Dawood
The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
J Clin Oncol 28:92-8. 2010..CONCLUSION Our results show that women with HER2/neu-positive disease who received trastuzumab had improved prognosis compared with women with HER2/neu-negative disease... - Acute myeloid leukemia after adjuvant breast cancer therapy in older women: understanding riskDebra A Patt
Department of Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 25:3871-6. 2007..The purpose of this study was to determine the risk of developing acute myeloid leukemia (AML) after adjuvant chemotherapy for breast cancer in older women... - Comparative analysis of sentinel lymph node operation in male and female breast cancer patientsJudy C Boughey
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
J Am Coll Surg 203:475-80. 2006..Intraoperative SLN evaluation should be considered in the surgical management of male breast cancer... - Pathologic complete response in breast cancer patients receiving anthracycline- and taxane-based neoadjuvant chemotherapy: evaluating the effect of race/ethnicityMariana Chavez-MacGregor
Division of Cancer Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
Cancer 116:4168-77. 2010..The current study was conducted to evaluate the influence of race/ethnicity and tumor subtype in pathologic complete response (pCR) following treatment with neoadjuvant chemotherapy... - Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancerSao Jiralerspong
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, 77030 4009, USA
J Clin Oncol 27:3297-302. 2009..Our purpose was to determine whether metformin use was associated with a change in pathologic complete response (pCR) rates in diabetic patients with breast cancer receiving neoadjuvant chemotherapy... - Cardiac morbidity of adjuvant radiotherapy for breast cancerDebra A Patt
Department of Medical Oncology, Houston, TX 77030, USA
J Clin Oncol 23:7475-82. 2005..05 (95% CI, 0.95 to 1.17) for heart failure. CONCLUSION: With up to 15 years of follow-up there were no significant differences in cardiac morbidity after radiation for left- versus right-sided breast cancer... - Supraclavicular radiation for breast cancer does not increase the 10-year risk of strokeWendy A Woodward
Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 106:2556-62. 2006.... - Congestive heart failure in older women treated with adjuvant anthracycline chemotherapy for breast cancerMary C Pinder
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 25:3808-15. 2007..Limited data are available on long-term cardiac safety of adjuvant anthracycline chemotherapy in breast cancer patients over age 65 years. We evaluated rates and predictors of congestive heart failure (CHF) in this population... - Complications associated with erythropoietin-stimulating agents in patients with metastatic breast cancer: a Surveillance, Epidemiology, and End Results-Medicare studyMariana Chavez-MacGregor
Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 117:3641-9. 2011..The authors evaluated the patterns of use and the risk of thromboembolic events (TEE) associated with erythropoietin-stimulating agents (ESAs) in older patients with metastatic breast cancer who were receiving chemotherapy... - Locoregional control of clinically diagnosed multifocal or multicentric breast cancer after neoadjuvant chemotherapy and locoregional therapyJulia L Oh
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcolmbe Blvd, Unit 1202, Houston, TX 77030, USA
J Clin Oncol 24:4971-5. 2006.... - Completion of adjuvant radiation therapy among women with breast cancerTomasz P Srokowski
Department of Cancer Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Cancer 113:22-9. 2008..Optimal treatment for breast cancer often involves lengthy multimodality care including 5 to 6 weeks of radiotherapy, but few studies have evaluated adherence to radiotherapy outside the context of a therapeutic clinical trial... - Trends in survival over the past two decades among white and black patients with newly diagnosed stage IV breast cancerShaheenah Dawood
Department of Breast Medical Oncology and Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 4009, USA
J Clin Oncol 26:4891-8. 2008..The aim of this study was to evaluate trends in and factors affecting survival in a large population-based cohort of patients with newly diagnosed stage IV breast cancer... - Patterns of treatment for early stage breast cancers at the M. D. Anderson Cancer Center from 1997 to 2004Yu Shen
Department of Biostatistics, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Cancer 115:2041-51. 2009..D. Anderson Cancer Center (MDACC)... - Overall survival and cause-specific mortality of patients with stage T1a,bN0M0 breast carcinomaEmer O Hanrahan
Departments of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Unit 10, Houston, TX 77030, USA
J Clin Oncol 25:4952-60. 2007.... - Trends for inflammatory breast cancer: is survival improving?Ana M Gonzalez-Angulo
Department of Breast Medical Oncology, Unit 1354, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030 4009, USA
Oncologist 12:904-12. 2007..Clinical trials focusing on the management of this aggressive disease are warranted. Disclosure of potential conflicts of interest is found at the end of this article... - A detailed evaluation of cardiac toxicity: a phase II study of doxorubicin and one- or three-hour-infusion paclitaxel in patients with metastatic breast cancerSharon H Giordano
Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 8:3360-8. 2002..4%) who received a dose < or = 360 mg/m2 (P = 0.002). CONCLUSIONS: When the doxorubicin dose exceeds 360 mg/m2, the combination of bolus doxorubicin and paclitaxel presents unacceptable cardiac risk... - Brachytherapy for accelerated partial-breast irradiation: a rapidly emerging technology in breast cancer careGrace L Smith
The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
J Clin Oncol 29:157-65. 2011..It is currently used in the community setting, although its efficacy has yet to be validated in prospective comparative trials. Frequency and factors influencing use have not been previously identified... - Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancerAman U Buzdar
Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Unit 424, Houston, TX 77030, USA
J Clin Oncol 23:3676-85. 2005.... - Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancerTomasz P Srokowski
Division of Cancer Medicine, and Department of Breast Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
J Clin Oncol 27:2170-6. 2009..To evaluate whether diabetes affects patterns of adjuvant chemotherapy use, toxic effects of chemotherapy, and breast cancer outcomes... - Improvement in breast cancer outcomes over time: are older women missing out?Benjamin D Smith
The University of Texas MD Anderson Cancer Center, Houston, USA
J Clin Oncol 29:4647-53. 2011.... - Predictors of invasive breast cancer in patients with an initial diagnosis of ductal carcinoma in situ: a guide to selective use of sentinel lymph node biopsy in management of ductal carcinoma in situTina W F Yen
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
J Am Coll Surg 200:516-26. 2005..Risks and benefits of SLNB should be discussed with patients who are younger, are diagnosed by core-needle biopsy, or have large or high-grade DCIS... - Anthracycline regimen adherence in older patients with early breast cancerCarlos H Barcenas
Department of Hematology and Oncology, TheUniversity of Texas MD Anderson Cancer Center, Houston, Texas, USA
Oncologist 17:303-11. 2012..Rates of anthracycline adherence in breast cancer (BC) patients are unknown, but noncompletion of chemotherapy is associated with worse outcomes... - A phase 1 study of weekly everolimus (RAD001) in combination with docetaxel in patients with metastatic breast cancerStacy Moulder
Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas Department of Investigational Cancer Therapeutics Phase I Program, The University of Texas MD Anderson Cancer Center, Houston, Texas
Cancer 118:2378-84. 2012..Inhibition of mammalian target of rapamycin with everolimus may improve the efficacy of taxanes. Everolimus and docetaxel are both metabolized by CYP3A4, which could result in a pharmacokinetic (PK) interaction... - Referral to medical oncology: a crucial step in the treatment of older patients with stage III colon cancerRuiLi Luo
Sealy Center on Aging, Department of Preventive Medicine and Community Health, University of Texas Medical Branch at Galveston, Galveston, Texas, USA
Oncologist 11:1025-33. 2006..Ensuring that high-risk patients are referred to medical oncology is a crucial step in quality care for patients with colon cancer... - The association of breast cancer and meningioma in men and womenGanesh Rao
Department of Neurosurgery, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Neurosurgery 65:483-9; discussion 489. 2009..An association between breast cancer and intracranial meningioma has been described in women. We sought to determine whether this connection exists in men as well, hypothesizing that causes unrelated to sex may be responsible... - Outcomes and cost of outpatient or inpatient management of 712 patients with febrile neutropeniaLinda S Elting
Department of Biostatistics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd Unit 447, Houston, TX 77030, USA
J Clin Oncol 26:606-11. 2008..We retrospectively compared the outcomes and costs of outpatient and inpatient management of low-risk outpatients who presented to an emergency department with febrile neutropenia (FN)... - Hazard of Recurrence among Women after Primary Breast Cancer Treatment--A 10-Year Follow-up Using Data from SEER-MedicareLee Cheng
Corresponding Author Lee Cheng, Department of Clinical Effectiveness, Unit 1425, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030
Cancer Epidemiol Biomarkers Prev 21:800-9. 2012..Few studies have used SEER-Medicare data to describe recurrence of breast cancer after primary treatment for U.S. women... - Problems in transition and quality of care: perspectives of breast cancer survivorsAimee Kendall Roundtree
The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Unit 1465, Houston, TX 77030, USA
Support Care Cancer 19:1921-9. 2011..We conducted a qualitative study to explore breast cancer survivors' perceptions and attitudes about their current healthcare utilization, screening, and information needs... - Breast cancer in menSharon H Giordano
The University of Texas M D Anderson Cancer Center, Department of Breast Medical Oncology, 1515 Holcombe Boulevard, Box 424, Houston, TX 77030, USA
Ann Intern Med 137:678-87. 2002..Optimal management of breast cancer in men is unknown because the rarity of the disease precludes large randomized trials. A review of the literature was undertaken with emphasis on articles published over a 10-year period... - Breast carcinoma and antihypertensive therapySharon H Giordano
Cancer 98:1334-6. 2003 - Efficacy of anastrozole in male breast cancerSharon H Giordano
University of Texas M. D. Anderson Cancer Center, Houston 77030, USA
Am J Clin Oncol 25:235-7. 2002..D. Anderson from 1990 to 1999 were reviewed. Five male patients with metastatic breast cancer who were treated at M. D. Anderson with anastrozole were identified. We now report on these five cases... - The role of the surgeon in whether patients with lymph node-positive colon cancer see a medical oncologistRuiLi Luo
Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas 77555, USA
Cancer 109:975-82. 2007..Chemotherapy improves survival for patients with stage III colon cancer, but some older patients with lymph node-positive colon cancer do not see a medical oncologist and, thus, do not receive adjuvant chemotherapy... - Leuprolide acetate plus aromatase inhibition for male breast cancerSharon H Giordano
J Clin Oncol 24:e42-3. 2006 - Time to remove the subspecialty blinders: breast cancer does not exist in isolationSharon H Giordano
J Natl Cancer Inst 100:230-1. 2008 - Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric OncologyHans Wildiers
Department of General Medical Oncology, University Hospital Gasthuisberg, Leuven, Belgium
Lancet Oncol 8:1101-15. 2007..The available evidence was reviewed and synthesised to provide consensus recommendations regarding the care of breast cancer in older adults... - Local recurrence or cardiovascular disease: pay now or laterSharon H Giordano
J Natl Cancer Inst 99:340-1. 2007
Research Grants
- Adherence Among Older Women with Breast CancerSharon Giordano; Fiscal Year: 2007..The proposed studies and career development activities will provide the applicant with the skills to develop into an independent investigator. ..