Research Topics
Genomes and Genes | Soledad A FernandezSummaryAffiliation: The Ohio State University Country: USA Publications
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Publications
Reliability of surgical skills scores in otolaryngology residents: analysis using generalizability theorySoledad A Fernandez
Ohio State University, Columbus, USA
Eval Health Prof 31:419-36. 2008..Rater disagreement introduced only small error into scores. The WS1 provides small measurement error, with two raters and two bones for each participant...- E2f3a and E2f3b contribute to the control of cell proliferation and mouse developmentJean Leon Chong
Human Cancer Genetics Program, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio 43210, USA
Mol Cell Biol 29:414-24. 2009..Together, we conclude that the contributions of E2F3a and E2F3b in cell proliferation and development are context dependent... - Allele-specific tumor spectrum in pten knockin miceHui Wang
Department of Molecular Genetics, College of Biological Sciences, Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA
Proc Natl Acad Sci U S A 107:5142-7. 2010..These data demonstrate that the variable tumor phenotypes observed in patients with Cowden and BRR syndromes can be attributed to specific mutations in PTEN that alter protein function through distinct mechanisms... - Timing of correct parenteral antibiotic initiation and outcomes from severe bacterial community-acquired pneumonia in childrenJennifer A Muszynski
Department of Pediatrics, Nationwide Children s Hospital, Columbus, OH, USA
Pediatr Infect Dis J 30:295-301. 2011..We hypothesized that longer time to initiation of correct parenteral antibiotic would be associated with longer durations of mechanical ventilation, intensive care unit length of stay, and hospital length of stay... - Pten in stromal fibroblasts suppresses mammary epithelial tumoursANTHONY J TRIMBOLI
Department of Molecular Genetics, College of Biological Sciences, The Ohio State University, Columbus, Ohio 43210, USA
Nature 461:1084-91. 2009..These findings identify the Pten-Ets2 axis as a critical stroma-specific signalling pathway that suppresses mammary epithelial tumours... - Modeling and detection of respiratory-related outbreak signaturesPeter F Craigmile
Department of Statistics, 404 Cockins Hall, 1958 Neil Avenue, Columbus, OH 43210, USA
BMC Med Inform Decis Mak 7:28. 2007.... - Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformationMurali V P Nadella
Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA
Retrovirology 5:46. 2008..The expression of PTHrP and the PTH/PTHrP receptor during immortalization or transformation of lymphocytes by HTLV-1 has not been investigated... - Indirubins decrease glioma invasion by blocking migratory phenotypes in both the tumor and stromal endothelial cell compartmentsShanté P Williams
Dardinger Laboratory for Neuro oncology and Neurosciences, Department of Neurological Surgery, The Ohio State University Medical Center and James Comprehensive Cancer Center, Columbus, Ohio 43210, USA
Cancer Res 71:5374-80. 2011..Overall, our findings suggest that indirubin inhibition of GSK-3 offers a novel treatment paradigm to target 2 of the most important interacting cellular compartments in heterotypic models of cancer... - Pediatric pedestrian injuries and associated hospital resource utilization in the United States, 2003Kristen A Conner
Center for Injury Research and Policy, The Research Institute at Nationwide Children s Hospital, 700 Children s Drive, Columbus, OH 43205, USA
J Trauma 68:1406-12. 2010.... - Resident training in developmental/behavioral pediatrics: where do we stand?Craig D Boreman
Department of Pediatrics, College of Medicine, Children s Hospital, The Ohio State University, Columbus, Ohio, USA
Clin Pediatr (Phila) 46:135-45. 2007..Our data provide direction for the ongoing refinement of pediatric education that is based on feedback from currently practicing pediatricians... - Mouse development with a single E2F activatorShih Yin Tsai
Department of Molecular Genetics, College of Biological Sciences, The Ohio State University, Columbus, Ohio 43210, USA
Nature 454:1137-41. 2008..These findings provide a molecular basis for the observed specificity among E2F activators during development... - Monocyte mRNA phenotype and adverse outcomes from pediatric multiple organ dysfunction syndromeMark W Hall
Department of Pediatrics, Davis Heart and Lung Research Institute, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA
Pediatr Res 62:597-603. 2007..02). These data suggest that adverse outcomes from pediatric MODS are associated with an anti-inflammatory monocyte mRNA phenotype. Future studies are warranted to explore mechanisms of immunodepression in pediatric critical illness... - Rapid fluid resuscitation in pediatrics: testing the American College of Critical Care Medicine guidelineMichael J Stoner
Section of Emergency Medicine, Columbus Children s Hospital, Columbus, OH 43205, USA
Ann Emerg Med 50:601-7. 2007..Of 3 commonly used, inexpensive methods of fluid delivery, we hypothesized that only use of a manual push-pull system will permit guideline adherence... - Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphomaBEVIN ZIMMERMAN
Department of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210 1093, USA
Leuk Res 35:1491-7. 2011..Our data provide new directions for the treatment of ATL and support the further development of AR-42 against HTLV-1-associated lymphoid malignancies...