Research Topics
Species | Eric L ChangSummaryAffiliation: The University of Texas Country: USA Publications
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Publications
Spinal myxopapillary ependymoma outcomes in patients treated with surgery and radiotherapy at M.D. Anderson Cancer CenterSerap Akyurek
Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA
J Neurooncol 80:177-83. 2006..Regardless of the extent of resection, adjuvant RT appears to significantly reduce the rate of tumor progression. Failures occurred exclusively in the neural axis, mainly at the primary site...- Acute toxicity and treatment interruption related to electron and photon craniospinal irradiation in pediatric patients treated at the University of Texas M. D. Anderson Cancer CenterEric L Chang
Department of Radiation Oncology, University of Texas, M D Anderson Cancer Center, Houston, TX, USA
Int J Radiat Oncol Biol Phys 52:1008-16. 2002..To determine the incidence of acute toxicity and treatment interruption associated with electron and photon craniospinal irradiation (CSI) in children treated with or without chemotherapy... - Focal and craniospinal irradiation for patients with intracranial germinoma and patterns of failureQuynh-Nhu Nguyen
Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 107:2228-36. 2006..04). CONCLUSIONS: Although focal techniques of irradiation with chemotherapy are attractive methods that limited the volume irradiated, the strategy appeared to be associated with increased rates of failures in the brain and spine... - Stereotactic radiosurgery and radiation therapy for spinal tumorsSimon S Lo
Department of Radiation Medicine, Ohio State University Medical Center, Columbus, OH 43210, USA
Expert Rev Neurother 7:85-93. 2007..Data on spinal stereotactic radiosurgery and radiotherapy have emerged in recent years. This review summarizes the clinical applications of stereotactic radiosurgery and radiotherapy for spinal tumors... - Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failureEric L Chang
Departments of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Neurosurg Spine 7:151-60. 2007..The authors report data concerning the safety, effectiveness, and patterns of failure obtained in a Phase I/II study of stereotactic body radiotherapy (SBRT) for spinal metastatic tumors... - A pilot study of neurocognitive function in patients with one to three new brain metastases initially treated with stereotactic radiosurgery aloneEric L Chang
Department of Radiation Oncology, The University of Texas, Houston, Texas 77030, USA
Neurosurgery 60:277-83; discussion 283-4. 2007..This report provides data from a pilot study in which neurocognitive function (NCF) was prospectively measured for patients with one to three newly diagnosed brain metastases treated with initial SRS alone... - Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trialEric L Chang
Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX, USA
Lancet Oncol 10:1037-44. 2009..We proposed that the learning and memory functions of patients who undergo SRS plus WBRT are worse than those of patients who undergo SRS alone. We did a randomised controlled trial to test our prediction... - Outcome variation among "radioresistant" brain metastases treated with stereotactic radiosurgeryEric L Chang
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Neurosurgery 56:936-45; discussion 936-45. 2005..To determine the influence of histopathological diagnosis on the outcome of "radioresistant" brain metastases treated with stereotactic radiosurgery (SRS)... - Phase I clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic body radiotherapy for spinal metastasesEric L Chang
Department of Radiation Oncology, Unit 97, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 59:1288-94. 2004..To evaluate in a Phase I study the safety, feasibility, and patient-positioning accuracy of treating patients with intensity-modulated, near-simultaneous, computed tomographic (CT) image-guided stereotactic body radiotherapy (SBRT)... - Diagnosis and management of central nervous system metastases from breast cancerEric L Chang
Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Oncologist 8:398-410. 2003..Despite advances in neuroimaging, surgery, and radiation therapy, novel treatments are needed to improve the effectiveness of treatments for CNS metastases, especially LM, while reducing attendant neurotoxicity... - Evaluation of peritumoral edema in the delineation of radiotherapy clinical target volumes for glioblastomaEric L Chang
Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 68:144-50. 2007..To evaluate the spatial relationship between peritumoral edema and recurrence pattern in patients with glioblastoma (GBM)... - Hypofractionated radiotherapy for elderly or younger low-performance status glioblastoma patients: outcome and prognostic factorsEric L Chang
Division of Radiation Oncology, Brain Tumor Center, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 56:519-28. 2003..To evaluate the outcome for elderly or younger poor prognosis glioblastoma patients treated with hypofractionated radiotherapy (HypoRT)... - Verification techniques and dose distribution for computed tomographic planned supine craniospinal radiation therapyEric L Chang
Division of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Med Dosim 28:127-31. 2003.... - The role of tumor size in the radiosurgical management of patients with ambiguous brain metastasesEric L Chang
Division of Radiation Oncology, Brain Tumor Center, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
Neurosurgery 53:272-80; discussion 280-1. 2003..To identify a size cutoff below which it is safe to observe obscure brain lesions suspected of being metastases so that treatment of nonmetastases can be avoided... - Standard and novel radiotherapeutic approaches to neoplastic meningitisEric L Chang
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 97, Houston, TX 77030, USA
Curr Oncol Rep 5:24-8. 2003..A case report highlighting the use of radiotherapy for palliation in a patient with neoplastic meningitis is presented at the end of this article... - Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastasesUgur Selek
Department of Radiation Oncology, Brain Tumor Center, The University of Texas, M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 59:1097-106. 2004..A prospective study is needed to assess the role of WBRT in patients with melanoma brain metastasis... - Optimal treatment planning for skull base chordoma: photons, protons, or a combination of both?Mylin A Torres
Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 74:1033-9. 2009..We compared dosimetry of proton (PR), intensity modulated radiation therapy (IMRT) photon (PH), and combined PR and IMRT PH (PP) irradiation of skull base chordomas to determine the most optimal technique... - Multimodality treatment of osteosarcoma: radiation in a high-risk cohortAnita Mahajan
Department of Radiation Oncology, UT M D Anderson Cancer Center, Houston, Texas, USA
Pediatr Blood Cancer 50:976-82. 2008..Chemotherapy during radiation and/or bone-seeking radioisotope therapy (153-samarium; 1 mCi/kg) during radiation may improve osteosarcoma cancer control... - Stereotactic radiosurgical treatment of cerebral metastases arising from breast cancerSerap Akyurek
Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
Am J Clin Oncol 30:310-4. 2007..This study was undertaken to evaluate the outcome of patients undergoing stereotactic radiosurgery (SRS) as primary or salvage treatment of brain metastases arising from breast cancer... - Near simultaneous computed tomography image-guided stereotactic spinal radiotherapy: an emerging paradigm for achieving true stereotaxyAlmon S Shiu
Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 57:605-13. 2003..To report treatment setup data from an emerging technique using near-simultaneous computed tomography (CT) image-guided stereotactic radiotherapy for the treatment of spinal and paraspinal tumors... - Management of spinal metastases from renal cell carcinoma using stereotactic body radiotherapyQuynh Nhu Nguyen
Department of Radiation Oncology, The University of Texas, M D Anderson Cancer Center, Houston, Texas 77030, USA
Int J Radiat Oncol Biol Phys 76:1185-92. 2010..To evaluate the outcomes associated with stereotactic body radiotherapy (SBRT) in the management of spinal metastases from renal cell carcinoma (RCC)... - Stereotactic body radiation therapy: a novel treatment modalitySimon S Lo
Department of Radiation Oncology, Arthur G James Cancer Hospital, Ohio State University College of Medicine, 300 West 10th Avenue, Columbus, OH 43210, USA
Nat Rev Clin Oncol 7:44-54. 2010..The results of these clinical trials will better define the role of SBRT in cancer management. This article will review the radiobiologic, technical, and clinical aspects of SBRT... - Case-control study of stereotactic radiosurgery for recurrent glioblastoma multiformeAnita Mahajan
Division of Radiation Oncology and the Department of Neurosurgery, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
J Neurosurg 103:210-7. 2005..The role of stereotactic radiosurgery (SRS) for recurrent glioblastoma multiforme (GBM) was evaluated in a case-control study... - Radiation-induced middle ear and mastoid opacification in skull base tumors treated with radiotherapyGary V Walker
Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 81:e819-23. 2011..To assess the incidence of middle ear (ME) pathology in patients treated with radiotherapy (RT) for skull base tumors... - Automatic target localization and verification for on-line image-guided stereotactic body radiotherapy of the spineCongjun Wang
Department of Radiation Physics, The University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
Technol Cancer Res Treat 6:187-96. 2007..Application of the program in actual IG-SBRT cases demonstrated that it was accurate, fast, and reliable. It serves as a useful tool for image-guided radiotherapy where high precision of target localization is required... - Intracranial meningeal hemangiopericytoma: the role of radiotherapy: report of 29 cases and review of the literatureSerdar Soyuer
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 100:1491-7. 2004..Based on literature review and the patterns of failure in the current series, attempting to perform GTR followed by limited-field radiotherapy appeared to represent a reasonable approach for the initial management of M-HPC... - Radiotherapy after surgery for benign cerebral meningiomaSerdar Soyuer
Department of Radiation Oncology, M.D. Anderson Cancer Center, The University of Texas, 1515 Holcombe Blvd, Unit 97, Houston, TX 77030, USA
Radiother Oncol 71:85-90. 2004..However, only a prospective randomized trial can adequately determine whether adjuvant or delayed radiotherapy is the better approach in patients with subtotally resected benign meningioma... - Treatment planning with protons for pediatric retinoblastoma, medulloblastoma, and pelvic sarcoma: how do protons compare with other conformal techniques?Catherine T Lee
Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 63:362-72. 2005..As dose-volume parameters are expected to correlate with acute and late toxicity, proton therapy should receive serious consideration as the preferred technique for the treatment of pediatric tumors... - Dosimetric effect of translational and rotational errors for patients undergoing image-guided stereotactic body radiotherapy for spinal metastasesHe Wang
Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
Int J Radiat Oncol Biol Phys 71:1261-71. 2008..The results of this study provide guidance for the treatment planning process and recognition of the dosimetric consequences of daily patient treatment setup errors... - Stereotactic body radiation therapy for spinal metastasesSimon S Lo
Department of Radiation Oncology, Arthur G James Cancer Hospital, Ohio State University, Columbus, Ohio 43210, USA
Discov Med 9:289-96. 2010..The purpose of this review is to provide an overview of the current state of spine SBRT practice... - Prospective evaluation of spinal reirradiation by using stereotactic body radiation therapy: The University of Texas MD Anderson Cancer Center experienceAmit K Garg
Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Cancer 117:3509-16. 2011..The authors review a prospective series of spinal metastasis patients reirradiated with stereotactic body radiotherapy... - Intensity-modulated radiotherapy (IMRT) and conventional three-dimensional conformal radiotherapy for high-grade gliomas: does IMRT increase the integral dose to normal brain?Ulrich Hermanto
Department of Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 67:1135-44. 2007..To determine whether intensity-modulated radiotherapy (IMRT) treatment increases the total integral dose of nontarget tissue relative to the conventional three-dimensional conformal radiotherapy (3D-CRT) technique for high-grade gliomas... - Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastasesJohn H Suh
Cleveland Clinic Foundation, Brain Tumor Institute, Department of Radiation Oncology, Cleveland, OH 44195, USA
J Clin Oncol 24:106-14. 2006..To determine whether efaproxiral, an allosteric modifier of hemoglobin, improves survival in patients with brain metastases when used as an adjunct to whole-brain radiation therapy (WBRT)... - YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastomaChristopher E Pelloski
Department of Radiation Oncology, Neuro Oncology, and Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 11:3326-34. 2005..Here we test these findings in a larger series of patients with glioblastoma, and in particular, determine if tumor YKL-40 expression is associated with radiation response... - Portal imaging practice patterns of children's oncology group institutions: Dosimetric assessment and recommendations for minimizing unnecessary exposureArthur J Olch
Department of Radiation Oncology, University of Southern California Keck School of Medicine, Children s Hospital Los Angeles, Los Angeles, CA 90027, USA
Int J Radiat Oncol Biol Phys 67:594-600. 2007..To determine and analyze the dosimetric consequences of current portal imaging practices for pediatric patients, and make specific recommendations for reducing exposure from portal imaging procedures... - Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a phase 1-2 trialXin Shelley Wang
Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Lancet Oncol 13:395-402. 2012..We investigated the clinical benefit of SBRT for managing spinal metastases and reducing cancer-related symptoms... - Outcomes and prognostic factors for patients with brainstem metastases undergoing stereotactic radiosurgeryMustafa Aziz Hatiboglu
Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Neurosurgery 69:796-806; discussion 806. 2011..Treatment of tumors metastatic to the brainstem with stereotactic radiosurgery (SRS) has not been widely studied... - CNS germinomas: what is the best treatment strategy?Mersiha Hadziahmetovic
Department of Radiation Oncology, The University of Texas Medical Branch, Trauma Center, 301 University Boulevard, Galveston, TX 77555 1178, USA
Expert Rev Neurother 8:1527-36. 2008..Data on the use of different strategies in the treatment of CNS germinomas are emerging but a standard strategy has not been established. This article reviews the different strategies used in the management of CNS germinomas... - Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgeryChelsea C Pinnix
Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Int J Radiat Oncol Biol Phys 83:317-26. 2012..treatment toxicity is of concern. We report our results with whole abdominopelvic intensity-modulated radiation therapy (WAP-IMRT) as a component of multimodality therapy for DSCRT at a single institution... - The prognostic value of neurologic function in astrocytic spinal cord gliomaHoon K Lee
Department of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Neuro Oncol 5:208-13. 2003..We conclude that favorable NF may be associated with improved outcome in patients with astrocytic spinal cord glioma... - Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastasesNicholas S Boehling
Departments of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
J Neurosurg Spine 16:379-86. 2012.... - Cost-effectiveness analysis of a randomized study comparing radiosurgery with radiosurgery and whole brain radiation therapy in patients with 1 to 3 brain metastasesLincy S Lal
Ingenix Consulting Healthcare, Missouri City, TX, USA
Am J Clin Oncol 35:45-50. 2012..In this study, we compare 2 treatment options and determine cost-effectiveness and cost-utility... - Emerging role of proton beam radiation therapy for chordoma and chondrosarcoma of the skull baseQuynh Nhu Nguyen
Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Unit 97, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Curr Oncol Rep 10:338-43. 2008..Compared with other forms of radiation therapy, proton beam therapy has been used to increase the dose delivered to the tumor while elegantly sparing dosing to adjacent critical normal structures... - Role of stereotactic radiosurgery and fractionated stereotactic radiotherapy in the management of intracranial ependymomaSimon S Lo
Department of Radiation Oncology, Indiana Lions Gamma Knife Center, Indiana University Medical Center, 535 Barnhill Drive, RT 041, Indianapolis, IN 46202, USA
Expert Rev Neurother 6:501-7. 2006..Long-term follow-up is needed to determine the long-term efficacy and toxicities associated with these treatment modalities... - Induction treatment for diffuse intrinsic pontine glioma, experience of M.D. Anderson Cancer CenterJohannes E Wolff
Department of Pediatrics, M D Anderson Cancer Center, Houston, TX, USA
Anticancer Res 31:2265-9. 2011..The biology of diffuse intrinsic pontine glioma remains poorly understood and the dismal prognosis has not changed despite various attempts to add chemotherapy to standard radiation... - A quality assurance procedure to evaluate cone-beam CT image center congruence with the radiation isocenter of a linear acceleratorWeiliang Du
Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX, USA
J Appl Clin Med Phys 11:3297. 2010..The results from the new QA procedure are useful for guiding high-precision patient positioning in stereotactic body radiation therapy... - Stereotactic radiosurgery with and without whole-brain radiotherapy for newly diagnosed brain metastasesSimon S Lo
Department of Radiation Oncology, Indiana Lions Gamma Knife Center, Indiana University Medical Center, 535 Barnhill Drive, RT 041, Indianapolis, IN 46202, USA
Expert Rev Neurother 5:487-95. 2005..For certain radioresistant brain metastases, the benefit of whole-brain radiotherapy to patients who have stereotactic radiosurgery is uncertain... - Advances in radiation therapy of brain metastasisSimon S Lo
Department of Radiation Oncology, UH Seidman Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
Prog Neurol Surg 25:96-109. 2012..This review provides an overview of advances in the radiotherapeutic management of brain metastases... - An evaluation of radiation exposure from portal films taken during definitive course of pediatric radiotherapyRajat J Kudchadker
Department of Radiation Physics, Box 94, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Int J Radiat Oncol Biol Phys 59:1229-35. 2004..The objective of this study was to quantify the radiation dose from portal imaging delivered within and outside the radiation treatment field during a course of radiation therapy... - Use of a deformable atlas to identify cryptic critical structures in the treatment of glioblastoma multiformeDavid C Weksberg
MD Anderson Cancer Center, Department of Radiation Oncology, University of Texas, Houston, Texas, United States of America
PLoS ONE 7:e32098. 2012..2%. Overall, our results demonstrate the feasibility of incorporating tools for cryptic critical structure identification into the treatment planning process for GBM... - Nonsmall cell lung cancer presenting with synchronous solitary brain metastasisChaosu Hu
Department of Radiation Oncology, Cancer Hospital, Fudan University, Shanghai, People's Republic of China
Cancer 106:1998-2004. 2006..Aggressive treatment to the lung may be justified for newly diagnosed thoracic Stage I NSCLC patients with a solitary brain metastasis, but not for locally advanced NSCLC patients with a solitary brain metastasis... - Stereotactic body radiosurgery for spinal metastases: a critical reviewArjun Sahgal
Department of Radiation Oncology, Sunnybrook Odette Cancer Center, University of Toronto, Toronto, ON, Canada
Int J Radiat Oncol Biol Phys 71:652-65. 2008 - Optimizing radiotherapy schedules for elderly glioblastoma multiforme patientsJames W Clarke
Department of Radiation Medicine, Arthur G James Cancer Hospital, The Ohio State University Medical Center, 300 West 10th Avenue, Ste 083A, Columbus, OH 43210, USA
Expert Rev Anticancer Ther 8:733-41. 2008..This review aims to evaluate the current state of knowledge on alternative radiotherapy schedules for elderly and poor-prognosis patients with glioblastoma... - Role of stereotactic radiosurgery and fractionated stereotactic radiotherapy in pediatric brain tumorsSimon S Lo
Department of Radiation Medicine, Arthur G James Cancer Hospital, Ohio State University Medical Center, 300 West 10th Avenue, Ste 088A, Columbus, OH 43210, USA
Expert Rev Neurother 8:121-32. 2008..SRS and FSRT can potentially add to the armamentarium against brain tumors in children. This article will review the role of SRS and FSRT in the management of pediatric brain tumors... - Use of thymosin beta15 as a urinary biomarker in human prostate cancerLloyd M Hutchinson
Program in Vascular Biology and Department of Surgery, Children's Hospital, Boston, MA 02115, USA
Prostate 64:116-27. 2005..CONCLUSIONS: We report that Tbeta15 is a urinary biomarker for CaP and suggest that Tbeta15, in combination with PSA, can be used to improve both the sensitivity and specificity of CaP diagnosis... - Development of a sensitive and specific enzyme-linked immunosorbent assay for thymosin beta15, a urinary biomarker of human prostate cancerLloyd M Hutchinson
Program in Vascular Biology and Department of Surgery, Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Clin Biochem 38:558-71. 2005..The assay will provide a tool for future clinical trials to validate urinary Tbeta15 as a predictive marker for recurrent CaP...