L G Boros

Summary

Affiliation: The Ohio State University
Country: USA

Publications

  1. ncbi Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation
    L G Boros
    The Ohio State University College of Medicine, Department of Surgery, Columbus 43210, USA
    Cancer Res 57:4242-8. 1997
  2. ncbi Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
    L G Boros
    Department of Surgery, The Ohio State University College of Medicine, Columbus 43210, USA
    Med Hypotheses 50:55-9. 1998
  3. ncbi Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor action
    L G Boros
    The Ohio State University College of Medicine, Department of Surgery, Columbus, USA
    Med Hypotheses 50:501-6. 1998
  4. ncbi Thiamine supplementation to cancer patients: a double edged sword
    L G Boros
    Ohio State University College of Medicine, Department of Surgery, Columbus 43210, USA
    Anticancer Res 18:595-602. 1998

Detail Information

Publications4

  1. ncbi Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation
    L G Boros
    The Ohio State University College of Medicine, Department of Surgery, Columbus 43210, USA
    Cancer Res 57:4242-8. 1997
    ..Therefore, enzymes or substrates regulating the nonoxidative synthesis of ribose could also be the sites to preferentially target tumor cell proliferation by new anticancer drugs...
  2. ncbi Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism?
    L G Boros
    Department of Surgery, The Ohio State University College of Medicine, Columbus 43210, USA
    Med Hypotheses 50:55-9. 1998
    ....
  3. ncbi Inhibition of the oxidative and nonoxidative pentose phosphate pathways by somatostatin: a possible mechanism of antitumor action
    L G Boros
    The Ohio State University College of Medicine, Department of Surgery, Columbus, USA
    Med Hypotheses 50:501-6. 1998
    ..Oxythiamine produced strong apoptosis in in-vitro hosted tumor cells. We hypothesize that somatostatin- and oxythiamine-induced antiproliferative action is mediated by the inhibition of G6PD, transketolase, or both...
  4. ncbi Thiamine supplementation to cancer patients: a double edged sword
    L G Boros
    Ohio State University College of Medicine, Department of Surgery, Columbus 43210, USA
    Anticancer Res 18:595-602. 1998
    ..Limited administration of thiamine and concomitant treatment with transketolase inhibitors is a more rational approach to treat cancer...