Research Topics
Species | Mark BloomstonSummaryAffiliation: The Ohio State University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Yttrium-90 microsphere induced gastrointestinal tract ulcerationChristopher D South
Division of Gastroenterology, Hepatology, and Nutrition The Ohio State University Medical Center, Columbus, Ohio, USA
World J Surg Oncol 6:93. 2008..We sought to determine a large academic institution's experience regarding the extent and frequency of gastrointestinal complications...- Update and review of the multidisciplinary management of stage IV colorectal cancer with liver metastasesSherif Raafat Zikry Abdel-Misih
The Ohio State University James Cancer Hospital, Columbus, Ohio 43210, USA
World J Surg Oncol 7:72. 2009..As a result, there have been improvements in patient care and survival. Naturally, the management of CLM has become increasingly complex in coordinating the various aspects of care in order to optimize patient outcomes... - Complete clinical response of metastatic hepatocellular carcinoma to sorafenib in a patient with hemochromatosis: a case reportBrian J So
The Ohio State University Medical Center, 395 W, 12th Avenue, Columbus, OH 43210, USA
J Hematol Oncol 1:18. 2008..No evidence of disease recurrence has been noted for 6 months after discontinuation of therapy... - MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitisMark Bloomston
Division of Surgical Oncology, James Cancer Hospital and Solove Research Institute, Ohio State University, Columbus, USA
JAMA 297:1901-8. 2007..While global microRNA (miRNA) expression patterns of many embryologic, physiologic, and oncogenic processes have been described, description of the role of miRNAs in ductal adenocarcinoma of the pancreas is lacking... - Stromal osteonectin overexpression is associated with poor outcome in patients with ampullary cancerMark Bloomston
Department of Surgery, Ohio State University, N924 Doan Hall, 410 W 10th Ave, Columbus, OH 43210, USA
Ann Surg Oncol 14:211-7. 2007..Osteonectin has been suggested to be important in the progression of pancreatic cancer but has not been correlated with survival. We determined the osteonectin expression and its influence on survival in patients with ampullary carcinoma... - Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical featuresMark Bloomston
Department of Surgery, The Ohio State University, Columbus, OH, USA
Ann Surg Oncol 16:2331-8. 2009..We have assessed the status of the Fhit and Wwox proteins encoded by DNA damage susceptible chromosome fragile sites encompassed by FHIT and WWOX tumor suppressor genes... - Cytoreduction results in high perioperative mortality and decreased survival in patients undergoing pancreatectomy for neuroendocrine tumors of the pancreasMark Bloomston
Department of Surgery, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA
J Gastrointest Surg 10:1361-70. 2006..However, cytoreduction resulting in incomplete tumor removal carries significant perioperative mortality without long-term survival benefit and should be discouraged... - Combined use of preoperative 18F FDG-PET imaging and intraoperative gamma probe detection for accurate assessment of tumor recurrence in patients with colorectal cancerIsmet Sarikaya
Division of Nuclear Medicine, Section of PET, Department of Radiology, The Ohio State University, Columbus, OH 43210, USA
World J Surg Oncol 5:80. 2007.... - Radioimmunoguided surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: past, present, and futureDuxin Sun
Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA
J Surg Oncol 96:297-308. 2007..PET/CT image-guided surgery only detects later stage disease. Fluorescence image-guided surgery using anti-TAG-72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors... - Intraoperative assessment of pancreatic neck margin at the time of pancreaticoduodenectomy increases likelihood of margin-negative resection in patients with pancreatic cancerMary Dillhoff
Department of Surgery, Ohio State University, 410 W 10th Ave, N924 Doan Hall, Columbus, OH 43210, USA
J Gastrointest Surg 13:825-30. 2009..We sought to review our experience with pancreaticoduodenectomy (PD) for pancreatic cancer to determine the impact of intraoperative frozen section (FS) analysis on margin-negative resection and long-term outcome... - Failure of normalization of CA19-9 following resection for pancreatic cancer is tantamount to metastatic diseaseSherif R Z Abdel-Misih
Division of Surgical Oncology, The Ohio State University Medical Center James Cancer Hospital, Columbus, OH, USA
Ann Surg Oncol 18:1116-21. 2011..However, little has been reported on outcomes of patients in whom CA19-9 never normalizes. We hypothesize that failure of CA19-9 normalization within 6 months is prognostically equivalent to metastatic disease... - TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivoMark Bloomston
Department of Surgery, University of South Florida, PO Box 1289, Tampa, FL 33601, USA
Am J Surg 189:675-9. 2005..TIMP-1 is a reasonable molecular target in pancreatic cancer therapy... - FDG-PET scan in patients with clinically and/or radiologically suspicious colorectal cancer recurrence but normal CEAIsmet Sarikaya
Division of Nuclear Medicine, Section of PET, Department of Radiology, The Ohio State University, Columbus, OH 43210, USA
World J Surg Oncol 5:64. 2007..We aimed to review PET scans of patients with clinically and/or radiologically suspicious tumor recurrence but normal CEA... - Solid serous microcystic adenoma of the pancreasJordan R Stern
Department of Surgery, The Ohio State University, 410 W 10th Ave, N924 Doan, Columbus, OH 43210, USA
World J Surg Oncol 5:26. 2007..An extremely rare solid variant of serous microcystic adenoma lacking secretory capability has been described. Herein, we present the fourth described case of this solid variant and review the literature... - H-graft portacaval shunts versus TIPS: ten-year follow-up of a randomized trial with comparison to predicted survivalsAlexander S Rosemurgy
Department of Surgery, University of South Florida College of Medicine Tampa, FL 33601, USA
Ann Surg 241:238-46. 2005..To report long-term outcome of patients undergoing prosthetic 8-mm H-graft portacaval shunts (HGPCS) or TIPS and to compare actual with predicted survival data... - Early results of laparoscopic Heller myotomy do not necessarily predict long-term outcomeMark Bloomston
Department of Surgery, University of South Florida, P O Box 1289, Room F 145, Tampa, FL 33601, USA
Am J Surg 187:403-7. 2004..We sought to evaluate how patients' symptoms evolve after laparoscopic Heller myotomy... - Predictors of survival in periampullary cancers following pancreaticoduodenectomyIoannis Hatzaras
Department of Surgery, The Ohio State University, Columbus, OH, USA
Ann Surg Oncol 17:991-7. 2010..We sought to evaluate predictors of survival for periampullary cancers following pancreaticoduodenectomy to identify biologic behavior... - Differential gene expression in patients genetically predisposed to pancreatic cancerEmmanuel E Zervos
Arthur G James Cancer Hospital and Richard J Solove Research Institute, The Ohio State University, Columbus, Ohio, USA
J Surg Res 135:317-22. 2006..The purpose of this study was to identify novel genes expressed in patients with a presumed genetic predisposition or "familial" PCA... - Differential expression of the Tie-2 receptor and its ligands in human pancreatic tumorsAlan J Durkin
Department of Surgery, University of South Florida College of Medicine and Tampa General Hospital, Digestive Disorders Center, Tampa, FL, USA
J Am Coll Surg 199:724-31. 2004..Differential expression of Ang-2 in human tumors may be useful as a diagnostic and therapeutic target... - Elevated CA 19-9 portends poor prognosis in patients undergoing resection of biliary malignanciesIoannis Hatzaras
Department of Surgery, The Ohio State University Columbus, OH 43210, USA
HPB (Oxford) 12:134-8. 2010..The aim of the present study was to identify predictors of survival after resection... - Calponin is expressed in serous cystadenomas of the pancreas but not in adenocarcinomas or endocrine tumorsWilliam L Marsh
Department of Pathology, Ohio State University Medical Center, Columbus, OH 43210, USA
Appl Immunohistochem Mol Morphol 17:216-9. 2009..Calponin and alpha-inhibin are the most useful positive markers for SMA, and are negative in most entities in the differential diagnosis... - Pancreatic resection in the octogenarian: a safe option for pancreatic malignancyIoannis Hatzaras
Department of Surgery, The Ohio State University, Columbus, OH, USA
J Am Coll Surg 212:373-7. 2011..We assessed our institution's experience and outcomes with pancreatic resection for malignancy in patients in their ninth decade... - Repeat transarterial chemoembolization (TACE) for progressive hepatic carcinoid metastases provides results similar to first TACEKimberly A Varker
Division of Surgical Oncology, Department of Surgery, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
J Gastrointest Surg 11:1680-5. 2007..We sought to determine if patients with disease progression after TACE would benefit from repeat TACE... - Laparoscopic Nissen fundoplication offers high patient satisfaction with relief of extraesophageal symptoms of gastroesophageal reflux diseaseSteven Rakita
Department of Surgery, University of South Florida College of Medicine, Tampa, Florida, USA
Am Surg 72:207-12. 2006.... - Hepatic artery chemoembolization in 122 patients with metastatic carcinoid tumor: lessons learnedMark Bloomston
Department of Surgery, James Cancer Hospital and Solove Research Institute, Ohio State University Medical Center, Columbus, OH, 43210, USA
J Gastrointest Surg 11:264-71. 2007..Hepatic artery chemoembolization (HACE) is a treatment option in the management of metastatic carcinoid. We reviewed our experience to identify potential factors that influence survival... - Preoperative carbohydrate antigen 19-9 is most predictive of malignancy in older jaundiced patients undergoing pancreatic resectionMark Bloomston
Department of Surgery, Ohio State University, Columbus, OH 43210, USA
Pancreas 33:246-9. 2006..CONCLUSIONS: Age and preoperative jaundice are more predictive of malignancy than CA19-9 alone unless levels are greater than 150 U/mL. Preoperative CA19-9 levels should be interpreted within the context of these other clinical factors... - Post-shunt resource consumption favors small-diameter prosthetic H-graft portacaval shunt over TIPS for patients with poor hepatic reserveAlexander S Rosemurgy
Department of Surgery, University of South Florida, Tampa General Hospital, 1 Davis Boulevard, Box 1289, Room F 145, Tampa, FL 33601, USA
Ann Surg 237:820-5; discussion 825-7. 2003..To define the role of surgical shunting for patients with poor hepatic reserve (Child's class C) in the era of TIPS... - Esophagography predicts favorable outcomes after laparoscopic Nissen fundoplication for patients with esophageal dysmotilitySteven Rakita
Department of Surgery, University of South Florida College of Medicine, Tampa, FL, USA
J Am Coll Surg 201:335-42. 2005..Preoperative esophagography predicts successful outcomes after laparoscopic Nissen fundoplication for patients with manometric esophageal dysmotility... - MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survivalMary Dillhoff
Department of Surgery, The Ohio State University, 410 W 10th Ave, N924 Doan Hall, Columbus, OH 43210, USA
J Gastrointest Surg 12:2171-6. 2008..We sought to determine the expression pattern of miR-21 in pancreatic cancers and its impact on clinicopathologic characteristics... - Preoperative intervention does not affect esophageal muscle histology or patient outcomes in patients undergoing laparoscopic Heller myotomyMark Bloomston
Department of Surgery, Joy McCann Culverhouse Center for Swallowing Disorders, University of South Florida College of Medicine, Tampa, FL 33601, USA
J Gastrointest Surg 7:181-8; discussion 188-90. 2003..The amount of fibrosis in the esophageal muscle is not related to preoperative intervention and is not predictive of outcomes... - Age affects presenting symptoms of achalasia and outcomes after myotomySteven Rakita
Department of Surgery, University of South Florida College of Medicine, Tampa, Florida 33601, USA
Am Surg 71:424-9. 2005..All patients should expect significant reductions in symptoms of achalasia following myotomy. Age and duration of symptoms impact symptoms before and after myotomy, but neither seem to impact subjective measure of outcome... - Accessory spleen presenting as a mass in the tail of the pancreasGary Tozbikian
Department of Pathology, The Ohio State University, Columbus, OH 43210, USA
Ann Diagn Pathol 11:277-81. 2007..After a distal pancreatectomy was completed, microscopic examination revealed heterotopic splenic tissue... - 50-year appraisal of gastrinoma: recommendations for staging and treatmentE Christopher Ellison
Department of Surgery, The Ohio State University, Columbus, OH, USA
J Am Coll Surg 202:897-905. 2006.... - Esophagotomy during laparoscopic Heller myotomy cannot be predicted by preoperative therapies and does not influence long-term outcomeSteven Rakita
Department of Surgery, University of South Florida College of Medicine, Tampa, Florida, USA
J Gastrointest Surg 9:159-64. 2005..Furthermore, complications after esophagotomy are infrequent and outcomes are indistinguishable from those of patients undergoing uneventful myotomy... - Reoperative fundoplications are effective treatment for dysphagia and recurrent gastroesophageal refluxAlexander S Rosemurgy
Department of Surgery, University of South Florida, Tampa, Florida, USA
Am Surg 70:1061-7. 2004..Laparoscopic reoperations are generally possible. Reoperative fundoplications are effective treatment for dysphagia and recurrent gastroesophageal reflux, and their application is encouraged... - Epidermal growth factor receptor expression in pancreatic carcinoma using tissue microarray techniqueMark Bloomston
Department of Pathology, The Ohio State University, Columbus, Ohio, USA
Dig Surg 23:74-9. 2006..Immunohistochemical analysis of EGFR staining may help in identifying candidates for EGFR inhibitor therapy... - Surgery versus intra-arterial therapy for neuroendocrine liver metastasis: a multicenter international analysisSkye C Mayo
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ann Surg Oncol 18:3657-65. 2011..We sought to examine the relative efficacy of surgical management versus intra-arterial therapy (IAT) for NELM and determine factors predictive of survival... - Symptoms and antireflux medication use following laparoscopic Nissen fundoplication: outcome at 1 and 4 yearsMark Bloomston
Department of Surgery, University of South Florida, College of Medicine, Tampa, Florida, USA
JSLS 7:211-8. 2003..Although some patients return to antacid medications at late follow-up, they continue to have few symptoms and are pleased with their outcomes... - Surgical management of colorectal cancer in the laparoscopic era: a review of prospective randomized trialsMark Bloomston
Department of Surgery, The Ohio State University, 410 W. 10th Avenue, Columbus, OH 43210, USA
J Natl Compr Canc Netw 3:517-24. 2005..In this article, we review these randomized trials with particular attention to the perioperative effects of laparoscopic colectomy and the short-term oncologic outcomes... - Videoscopic Heller myotomy with intraoperative endoscopy promotes optimal outcomesMark Bloomston
Department of Surgery, University of South Florida, Tampa, USA
JSLS 6:133-8. 2002..We advocate concomitant endoscopy during Heller myotomy to guide myotomy and submit that routine fundoplication is clinically unnecessary... - Clinical factors predictive of malignant and premalignant cystic neoplasms of the pancreas: a single institution experienceNatalie B Jones
Department of Surgery, The Ohio State University Columbus, OH, USA
HPB (Oxford) 11:664-70. 2009..We sought to review our experience with the surgical management of cystic neoplasms of the pancreas to determine pre-operative clinical indicators of malignancy or premalignant (i.e. mucinous) lesions... - A single-institute experience with sorafenib in untreated and previously treated patients with advanced hepatocellular carcinomaStephanie M Balsom
Center for Biostatistics, Columbus, Ohio, USA
Oncology 78:210-2. 2010..Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Sorafenib is considered the standard of care for patients with advanced HCC... - Image guidance during abdominal exploration for recurrent colorectal cancerErgun Kocak
Department of Surgery, Division of Surgical Oncology, The Ohio State University, Columbus, Ohio, USA
Ann Surg Oncol 14:405-10. 2007..Few attempts have been made to apply this technology to gastrointestinal cancers. Our purpose was to determine if a computer-assisted navigation system could be accurately used at the time of abdominal exploration... - MicroRNAs in solid tumorsMary Dillhoff
Department of Surgery, Ohio State University, Columbus, Ohio 43210, USA
J Surg Res 154:349-54. 2009..These profiles have been used to not only classify tumors, but also to help predict survival and outcome. Herein, we review the role of miRNAs in the development and progression of solid tumors... - Fibrinogen gamma overexpression in pancreatic cancer identified by large-scale proteomic analysis of serum samplesMark Bloomston
Division of Surgical Oncology, James Cancer Hospital and Solove Research Institute, Columbus, Ohio, USA
Cancer Res 66:2592-9. 2006..Of these, fibrinogen gamma, a protein associated with the hypercoagulable state of pancreatic cancer, discriminated cancer from normal sera. Fibrinogen is a potential tumor marker in pancreatic cancer... - Selective application of fundoplication during laparoscopic heller myotomy ensures favorable outcomesMark Bloomston
Division of General Surgery, Department of Surgery, University of South Florida, Tampa 33601, USA
Surg Laparosc Endosc Percutan Tech 12:309-15. 2002..6). Overall improvement was seen in 86% of patients undergoing myotomy with fundoplication and in 97% without fundoplication (P = 0.06). Selective application of fundoplication during laparoscopic Heller myotomy promotes optimal outcomes... - Matrix metalloproteinases and their role in pancreatic cancer: a review of preclinical studies and clinical trialsMark Bloomston
Department of Surgery, University of South Florida, Tampa, FL 33601, USA
Ann Surg Oncol 9:668-74. 2002..These findings have led to several clinical trials using the MMP inhibitors Marimastat and BAY12-9566. Herein, we discuss the roles of MMPs and their inhibition in pancreatic cancer... - Renal haemodynamics and function following partial portal decompressionSharona Ross
Department of Surgery, University of South Florida, c o Tampa General Hospital Tampa, FL, USA
HPB (Oxford) 11:229-34. 2009..DISCUSSION: Partial portal decompression improves mild to moderate renal dysfunction in patients with cirrhosis. Early improvements in renal function after shunting begin to disappear by 1 year after shunting... - Complete response to radiation therapy of orbital metastasis from hepatocellular carcinomaAllison M Quick
Department of Radiation Medicine, Arthur G James Cancer Hospital, The Ohio State University Medical Center, Columbus, OH 43210, United States
World J Gastroenterol 15:6000-3. 2009..The patient continues to have local control in the orbit 1.7 years after therapy completion. All critical normal structures were kept below the tolerance dose using IMRT, and no toxicities were observed... - The complicated management of a patient following transarterial chemoembolization for metastatic carcinoidAndrew C Pearson
Department of Surgery, Ohio State University Medical Center, Columbus, Ohio, USA
World J Surg Oncol 6:125. 2008..Although it is a fairly safe procedure, it is not without its complications... - Pancreatectomy for non-pancreatic malignancies results in improved survival after R0 resectionKimberly A Varker
Department of Surgery and Division of Surgical Oncology, The Ohio State University Medical Center, Columbus, OH, USA
World J Surg Oncol 5:145. 2007..Its efficacy for non-pancreatic malignancies is less clear. We reviewed our experience with pancreatectomy for non-pancreatic malignancies to determine outcomes and identify predictors of survival... - A phase I study of the biomodulation of capecitabine by docetaxel and gemcitabine (mGTX) in previously untreated patients with metastatic adenocarcinoma of the pancreasMarisa E Hill
Ohio State University Comprehensive Cancer Center, Arthur James Cancer Hospital, Columbus, OH, 43210, USA
Cancer Chemother Pharmacol 67:511-7. 2011..Pancreas cancer remains a formidable challenge. We report the first prospective analysis of the 3-drug combination of gemcitabine (G), docetaxel (T) and capecitabine (X) (mGTX) with schedule modification to maximize biomodulation of X... - Expression of the p16INK4A/Cdkn2a gene is prevalently downregulated in human pheochromocytoma tumor specimensPeter Muscarella
Department of Surgery, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
Gene Expr 14:207-16. 2008..7%. Taken together, our results demonstrate that reduced expression of pl6 is a common event in human pheochromocytomas, and the primary cause for such downregulation is inactivating genetic abnormalities in the p16 gene... - Radical resection in signet ring carcinoma of the ampulla of Vater: report of an 11-year survivorMark Bloomston
Division of Surgical Oncology, James Cancer Hospital and Solove Research Institute, Columbus, Ohio 43210, USA
Am Surg 72:193-5. 2006..No distant or nodal metastases were seen (pT2N0M0). No adjuvant therapy was given, and the patient remains free of disease with 134 months of follow-up... - Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancersTanios Bekaii-Saab
The Ohio State University Comprehensive Cancer Center James Cancer Hospital and Solove Research Institute, Columbus, OH 43210, USA
J Clin Oncol 29:2357-63. 2011..Selumetinib is an inhibitor of MEK1/2, so this trial was designed to determine the safety and efficacy of selumetinib in BC... - Carcinosarcoma of the pancreas arising in a mucinous cystic neoplasmMark Bloomston
Department of Pathology, The Ohio State University, E-401 Doan Hall, 410 West 10th Avenue, Columbus, OH 43210, USA
Am Surg 72:351-5. 2006..To the best of our knowledge, this is the second case of carcinosarcoma with invasive epithelial and sarcomatous areas in the background of a mucinous cystic neoplasm of the pancreas... - Long-term efficacy of lymph node reoperation for persistent papillary thyroid cancerOsama Al-Saif
Department of Surgery, The Ohio State University, Columbus, Ohio 43210, USA
J Clin Endocrinol Metab 95:2187-94. 2010..The objective of the study was to determine the outcome of surgical resection of metastatic papillary thyroid cancer (PTC) in cervical lymph nodes after failure of initial surgery and I(131) therapy... - The spectrum of hematologic malignancies involving the pancreas: potential clinical mimics of pancreatic adenocarcinomaJonathan Rock
Department of Pathology, The Ohio State University Medical Center, Columbus, OH 43210 1218, USA
Am J Clin Pathol 137:414-22. 2012..Pancreatic masses are usually correctly identified clinically. Preoperative and operative sampling is strongly recommended when hematologic malignancies cannot be excluded... - Transcatheter arterial chemoembolization with or without radiofrequency ablation in the management of patients with advanced hepatic malignancyMark Bloomston
Department of Surgery, University of South Florida College of Medicine, Tampa 33601, USA
Am Surg 68:827-31. 2002..The addition of RFA to TACE improves survival in patients with unresectable primary or metastatic hepatic malignancies. RFA with TACE should be in the armamentarium of surgeons caring for patients with malignant liver lesions... - Thiazolidinediones downregulate Wnt/beta-catenin signaling via multiple mechanisms in breast cancer cellsPei Shan Wang
Department of Medicine, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA
J Surg Res 153:210-6. 2009..We sought to better define TZDs' antitumor effects and molecular mechanisms to permit rational utilization of these agents... - The mTOR pathway is frequently activated in pancreatic ductal adenocarcinoma and chronic pancreatitisAndrew M Bellizzi
Departments of Pathology, The Ohio State University Medical Center, Columbus, OH 43210 1218, USA
Appl Immunohistochem Mol Morphol 18:442-7. 2010..We performed immunohistochemistry for PTEN and p-RPS6 (major downstream mTOR effector) in a group of PDAs. An assessment of chronic pancreatitis (CP) and normal pancreas (NL) was performed in parallel... - Serous cystadenoma of the pancreas: clinical and pathological features in 33 patientsJorge Colonna
Department of Pathology, Ohio State University Medical Center, Columbus, Ohio 43210, USA
Pancreatology 8:135-41. 2008..To report the clinicopathological features of patients with serous cystadenomas of the pancreas... - Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4? T cells from patients with GI malignancyBethany L Mundy-Bosse
Department of Integrated Biomedical Sciences, The Ohio State University, Columbus, OH, USA
Cancer Immunol Immunother 60:1269-79. 2011..033). These data provide evidence for a unique relationship between specific cytokines, MDSC subsets, and IFN-? responsiveness in patients with GI malignancies... - Gastric duplication cysts expressing carcinoembryonic antigen mimicking cystic pancreatic neoplasms in two adultsJeffrey Johnston
Department of Surgery, Ohio State University Medical Center, Columbus, Ohio, USA
Am Surg 74:91-4. 2008..At operation, they were found to be gastric duplication cysts and were resected. We report the histologic findings and review of the current literature... - Atrial fibrillation after esophagectomy: an indicator of postoperative morbidityStanislaw P A Stawicki
Department of Surgery, The Ohio State University Medical Center, 395 W 12th Avenue, Suite 634 C, Columbus, OH 43210, USA
Gen Thorac Cardiovasc Surg 59:399-405. 2011..This study's primary goal is to better define the incidence, clinical patterns, and outcomes associated with the development of AF after esophagectomy... - Population pharmacokinetics of humanized monoclonal antibody HuCC49deltaCH2 and murine antibody CC49 in colorectal cancer patientsLanyan Fang
Division of Pharmaceutics, College of Pharmacy, The Ohio State University, 232 Parks Hall, 500 West 12th Avenue, Columbus, OH 43210, USA
J Clin Pharmacol 47:227-37. 2007..Clinical trial designs with at least 3 measurements of antibody disposition were found to be better than an empirical direct observation method for the optimal prediction of surgery time... - Liver anatomySherif R Z Abdel-Misih
Division of Surgical Oncology, The Ohio State University Medical Center, Arthur G James Cancer Hospital, Richard J Solove Research Institute, 410 West, 10th Avenue, N 924 Doan Hall, Columbus, OH 43210, USA
Surg Clin North Am 90:643-53. 2010..This article reviews the history, general anatomy, and the classification schemes of liver anatomy and their relevance to liver-directed therapies... - TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesisMark Bloomston
Department of Surgery, University of South Florida, Tampa, Florida 33601, USA
J Surg Res 102:39-44. 2002..This study demonstrates the potential role of TIMP-1 as a target in gene therapy for pancreatic cancer... - The "learning curve" in videoscopic Heller myotomyMark Bloomston
Department of Surgery, University of South Florida College of Medicine, Tampa, USA
JSLS 6:41-7. 2002..quot; After approximately 20 videoscopic Heller myotomies, surgeons can expect fewer conversions to open procedures, shorter hospital stays, and better symptomatic relief... - MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancerMark Bloomston
Department of Surgery, University of South Florida, Tampa, Florida 33601, USA
J Surg Res 102:35-8. 2002..e., human). Pharmacologic and gene therapy aimed at disturbing the MMP/TIMP balance in pancreatic cancer should be targeted toward tumor-specific mechanisms and warrants continued investigation... - Identification of molecular markers specific for pancreatic neuroendocrine tumors by genetic profiling of core biopsiesMark Bloomston
Surgery, Moffitt Cancer Center, Tampa, Florida 33612, USA
Ann Surg Oncol 11:413-9. 2004..These novel markers may prove useful as molecular markers or therapeutic targets unique to pancreatic neuroendocrine tumors... - Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitorXianhua Cao
Drug Discovery Support, Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, Connecticut, USA
Clin Cancer Res 14:1831-9. 2008..We sought to examine the synergistic antipancreatic cancer effect by simultaneously targeting hypoxic cancer cells with heat-shock protein 90 (HSP90) inhibitor and blockade of energy production... - 32P as an adjunct to standard therapy for locally advanced unresectable pancreatic cancer: a randomized trialAlexander Rosemurgy
Tampa General Hospital, University of South Florida, Tampa, FL, USA
J Gastrointest Surg 12:682-8. 2008..16). (32)P promoted tumor liquefaction, but did not decrease tumor size. Intratumoral (32)P was associated with more serious adverse events and did not improve survival for locally advanced unresectable pancreatic cancer...