Research Topics
| Raghava PotulaSummaryAffiliation: Temple University Country: USA Publications
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Detail Information
Publications
Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cellsServio H Ramirez
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
J Cereb Blood Flow Metab 29:1933-45. 2009..These observations provide a basis for antioxidant protection against brain endothelial injury caused by METH exposure...
Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairmentRaghava Potula
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
J Immunol 185:2867-76. 2010..Altogether, our data indicate that METH can cause T cell dysfunction via induction of oxidative stress and mitochondrial injury as underlying mechanism of immune impairment secondary to METH abuse...
Dyad of CD40/CD40 ligand fosters neuroinflammation at the blood-brain barrier and is regulated via JNK signaling: implications for HIV-1 encephalitisServio H Ramirez
Departments of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
J Neurosci 30:9454-64. 2010..These new findings support the concept that the CD40/CD40L dyad plays an important role in HIVE neuroinflammation...
HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventionsYuri Persidsky
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA
Brain Behav Immun 25:S61-70. 2011..Agonists of cannabinoid receptor 2 (CB?) possess potent anti-inflammatory and neuroprotective properties. We address multifaceted beneficial effects of CB? activation in the setting of HIV-1 brain infection and alcohol abuse...
