Research Topics
| Jean Y TangSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Novel Hedgehog pathway targets against basal cell carcinomaJean Y Tang
Department of Dermatology, San Francisco General Hospital, University of California, San Francisco, CA, USA
Toxicol Appl Pharmacol 224:257-64. 2007..Thus, sterols may be a new therapeutic target for the treatment of BCCs, and readily available agents such as statins (HMG-CoA reductase inhibitors) or vitamin D might be helpful in reducing BCC incidence...
Emerging treatments and signaling pathway inhibitorsJean Y Tang
Stanford University School of Medicine, Palo Alto, California, USA
Semin Cutan Med Surg 30:S14-8. 2011....
Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trialsJean Y Tang
Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA 94305, USA
J Natl Cancer Inst 103:1469-75. 2011....
Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trialJean Y Tang
Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA, USA
J Clin Oncol 29:3078-84. 2011....
Elucidating the role of molecular signaling pathways in the tumorigenesis of basal cell carcinomaJean Y Tang
Stanford University School of Medicine, Palo Alto, California, USA
Semin Cutan Med Surg 30:S6-9. 2011..To date, several agents have been developed-and some are in clinical trials-that hold promise for improved nonsurgical treatments for patients with Gorlin syndrome and those with locally advanced/metastatic BCCs...
Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomasJean Y Tang
Department of Dermatology, Stanford University School of Medicine, Redwood City, CA 94063 5334, USA
Cancer Prev Res (Phila) 4:744-51. 2011..Finally, topical vitamin D3 treatment of existing murine BCC tumors significantly decreases Gli1 and Ki67 staining. Thus, topical vitamin D3 acting via its HH inhibiting effect may hold promise as an effective anti-BCC agent...
High prevalence of vitamin D deficiency in patients with basal cell nevus syndromeJean Y Tang
Department of Dermatology, Stanford University Medical Center, 450 Broadway St, Pavilion C, Redwood City, CA 94063, USA
Arch Dermatol 146:1105-10. 2010..To evaluate vitamin D status in patients with basal cell nevus syndrome (BCNS) who practice photoprotection because of their genetic predisposition to skin cancer and to determine risk factors for deficiency...
Inverse association between serum 25(OH) vitamin D levels and non-melanoma skin cancer in elderly menJean Y Tang
Children s Hospital of Oakland Research Institute, USA
Cancer Causes Control 21:387-91. 2010..026) compared to those in the lowest quintile. Our results suggest that a diagnosis of NMSC is not a surrogate for adequate 25(OH)D levels or increased UV exposure, and high 25(OH)D levels may be associated with a reduced risk of NMSC...
Hat, shade, long sleeves, or sunscreen? Rethinking US sun protection messages based on their relative effectivenessEleni Linos
Department of Dermatology, Stanford University School of Medicine, 450 Broadway St, Pavillion C, Redwood City, CA 94063, USA
Cancer Causes Control 22:1067-71. 2011..Sun protection messages in the United States emphasize sunscreen use, although its efficacy in skin cancer prevention remains controversial...
Association of facial skin aging and vitamin D levels in middle-aged white womenAnne Lynn S Chang
Department of Dermatology, Stanford University School of Medicine, 450 Broadway, Pavilion C, MC 5334, Redwood City, CA 94305, USA
Cancer Causes Control 21:2315-6. 2010..Our results suggest an association between skin aging and 25(OH)D levels...
Sun protective behaviors and vitamin D levels in the US population: NHANES 2003-2006Eleni Linos
Department of Dermatology, Stanford University School of Medicine, Pavilion B 2nd Floor, 450 Broadway St, Redwood City, CA 94063, USA
Cancer Causes Control 23:133-40. 2012..Our aim was to investigate the relationship between different types of sun protective behaviors and serum 25(OH)D levels in the general US population...
Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growthJames Kim
Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA
Cancer Cell 17:388-99. 2010....
Genotype-phenotype correlations among pachyonychia congenita patients with K16 mutationsTeresa Fu
Department of Dermatology, Stanford University School of Medicine, Stanford, California 94063, USA
J Invest Dermatol 131:1025-8. 2011..Knowledge of the exact gene defect is likely to assist in predicting disease prognosis and clinical management...
Correlates of low bone mass in children with generalized forms of epidermolysis bullosaAnna L Bruckner
Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305 5168, USA
J Am Acad Dermatol 65:1001-9. 2011..Epidermolysis bullosa (EB) is a family of rare, heterogeneous, genetic disorders characterized by fragility of the skin and mucous membranes. Reduced bone mass and fractures have been recognized as complications of generalized forms of EB...
