Research Topics
| D A RelmanSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Genomic features of Bordetella parapertussis clades with distinct host species specificityMary M Brinig
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
Genome Biol 7:R81. 2006..The disease process in sheep is not well understood, nor are the genetic and transcriptional differences that might provide the basis for host specificity among ovine and human strains...- Absence of Kaposi's sarcoma-associated herpesvirus DNA in bacillary angiomatosis-peliosis lesionsD A Relman
Veterans Affairs Palo Alto Health Care System 154T, Palo Alto, CA 94304, USA
J Infect Dis 180:1386-9. 1999..Only 1 of 10 BA tissues, a splenic biopsy, was positive in this assay; this tissue was from a patient with concomitant KS of the skin. Thus, KSHV is probably not involved in the vascular proliferative response seen in BA-BP... - Detection and identification of previously unrecognized microbial pathogensD A Relman
Stanford University, California, USA
Emerg Infect Dis 4:382-9. 1998.... - The meaning and impact of the human genome sequence for microbiologyD A Relman
Dept of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305 5124, USA
Trends Microbiol 9:206-8. 2001..We also propose criteria for implicating a host gene in microbial pathogenesis, and urge consideration of a'second human genome project'... - The search for unrecognized pathogensD A Relman
Department of Medicine, Stanford University, Stanford, CA 94305, USA
Science 284:1308-10. 1999.... - Improved amplification of microbial DNA from blood cultures by removal of the PCR inhibitor sodium polyanetholesulfonateD N Fredricks
Department of Medicine, Division of Infectious Diseases, Stanford University Medical Center, Stanford, California 94305, USA
J Clin Microbiol 36:2810-6. 1998.... - Does blood of healthy subjects contain bacterial ribosomal DNA?S Nikkari
Department of Microbiology and Immunology and Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
J Clin Microbiol 39:1956-9. 2001..However, the origins and identities of these blood-associated bacterial rDNA sequences remain obscure... - Rhinosporidium seeberi: a human pathogen from a novel group of aquatic protistan parasitesD N Fredricks
Stanford University, Stanford, California, USA
Emerg Infect Dis 6:273-82. 2000..seeberi phylogeny recently suggested by another group. R. seeberi is not a classic fungus, but rather the first known human pathogen from the DRIPs clade, a novel clade of aquatic protistan parasites (Ichthyosporea)... - Bordetella species are distinguished by patterns of substantial gene loss and host adaptationC A Cummings
Departments of Microbiology and Immunology. Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
J Bacteriol 186:1484-92. 2004.... - Species- and strain-specific control of a complex, flexible regulon by Bordetella BvgASC A Cummings
VA Palo Alto Health Care System, 154T, Bldg 101, C4 151, 3801 Miranda Ave, Palo Alto, CA 94304, USA
J Bacteriol 188:1775-85. 2006..pertussis. We propose the concept of a "flexible regulon." This flexible regulon may prove to be important for pathogen evolution and the diversification of host range specificity... - Comparing functional genomic datasets: lessons from DNA microarray analyses of host-pathogen interactionsM Diehn
Department of Biochemistry, CCSR 2250, 269 Campus Drive, Stanford, CA 94305, USA
Curr Opin Microbiol 4:95-101. 2001..Comparisons between these large, highly parallel sets of experimental observations also emphasize important technical and experimental design issues as future challenges... - Infectious agents and the etiology of chronic idiopathic diseasesD N Fredricks
Stanford University School of Medicine, Department of Medicine Division of Infectious Diseases and Geographic Medicine, California, USA
Curr Clin Top Infect Dis 18:180-200. 1998.... - Localization of Tropheryma whippelii rRNA in tissues from patients with Whipple's diseaseD N Fredricks
Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, California, USA
J Infect Dis 183:1229-37. 2001..The location of bacterial rRNA in tissues from patients with Whipple's disease provides evidence that bacteria are growing outside cells and suggests that T. whippelii is not an obligate intracellular pathogen... - Using DNA microarrays to study host-microbe interactionsC A Cummings
Stanford University, Stanford, California, USA
Emerg Infect Dis 6:513-25. 2000..Host profiling might also identify gene expression signatures unique for each pathogen, thus providing a novel tool for diagnosis, prognosis, and clinical management of infectious disease... - Proinflammatory and proapoptotic activities associated with Bordetella pertussis filamentous hemagglutininT Abramson
Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
Infect Immun 69:2650-8. 2001..pertussis-host interaction... - Sequence variability in the first internal transcribed spacer region within and among Cyclospora species is consistent with polyparasitismC Olivier
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
Int J Parasitol 31:1475-87. 2001..This consistent and remarkable diversity among Cyclospora spp. ITS-1 sequences argues for polyparasitism and simultaneous transmission of multiple strains... - Bordetella bronchiseptica expresses the fimbrial structural subunit gene fimAJ S Boschwitz
Department of Microbiology and Immunology, Stanford University School of Medicne, California 94305, USA
J Bacteriol 179:7882-5. 1997..We have found that B. parapertussis and B. bronchiseptica, unlike B. pertussis, contain a full-length gene for the fimbrial subunit FimA. B. bronchiseptica expresses fimA in a BvgAS-dependent fashion... - Molecular characterization of Bordetella bronchiseptica filamentous haemagglutinin and its secretion machineryF Jacob-Dubuisson
INSERM U447, Institut de Biologie de Lille, France
Microbiology 146:1211-21. 2000..Characterization of FHA expression and function may provide clues as to the basis of host species tropism, tissue localization and receptor recognition... - Characterization of a highly conserved island in the otherwise divergent Bordetella holmesii and Bordetella pertussis genomesD A Diavatopoulos
Laboratory for Vaccine Preventable Diseases, National Institute of Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, P.O. Box 1, 3720 BA Bilthoven, The Netherlands
J Bacteriol 188:8385-94. 2006..holmesii may have significantly contributed to its emergence as a human pathogen. Horizontal gene transfer between B. pertussis and B. holmesii may also explain the unusually high sequence identity of their 16S rRNA genes...