Research Topics
| Kiki ChangSummaryAffiliation: Stanford University Country: USA Publications
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Detail Information
Publications
Anomalous prefrontal-subcortical activation in familial pediatric bipolar disorder: a functional magnetic resonance imaging investigationKiki Chang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
Arch Gen Psychiatry 61:781-92. 2004..Neuroimaging studies of adults with BD have implicated the dorsolateral prefrontal cortex (DLPFC) and anterior cingulate cortex (ACC) in the development of this disorder...- Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot studyKiki Chang
Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, Stanford, California 94305 5540, USA
J Child Adolesc Psychopharmacol 19:51-9. 2009..We sought to examine the effects of divalproex on the structure, chemistry, and function of specific brain regions in children at high-risk for BD... - Brain glutamatergic characteristics of pediatric offspring of parents with bipolar disorderManpreet Singh
Department of Psychiatry and Behavioral Sciences, Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
Psychiatry Res 182:165-71. 2010..Longitudinal studies are necessary to confirm whether prefrontal glutamate decreases only after the onset of full mania... - Subcortical volumetric correlates of anxiety in familial pediatric bipolar disorder: a preliminary investigationDiana I Simeonova
Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5540, USA
Psychiatry Res 173:113-20. 2009..The overlap between anxiety and familial pediatric BD suggests that anxiety may be one important area of future research in parsing out the heterogeneous nature and complex etiology of early-onset BD... - Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorderKirti Saxena
Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, School of Medicine, Stanford University, 401 Quarry Road, Stanford, CA 94305, USA
J Child Adolesc Psychopharmacol 16:252-9. 2006..The psychopharmacology of aggression in youth is relatively unexplored, even though such maladaptive aggression manifests across many different diagnoses... - Atomoxetine as an adjunct therapy in the treatment of co-morbid attention-deficit/hyperactivity disorder in children and adolescents with bipolar I or II disorderKiki Chang
Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
J Child Adolesc Psychopharmacol 19:547-51. 2009..We conducted an 8-week, open label study to study the efficacy and tolerability of adjunct atomoxetine in euthymic children and adolescents with BPD and ADHD... - The role of the amygdala in bipolar disorder developmentAmy Garrett
Stanford University School of Medicine, CA 94305, USA
Dev Psychopathol 20:1285-96. 2008..In addition, evidence is accumulating to suggest that this model has flexible outcomes, depending on factors intrinsic and extrinsic to BD, and may follow several possible paths across the course of maturational development... - Cortical magnetic resonance imaging findings in familial pediatric bipolar disorderKiki Chang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
Biol Psychiatry 58:197-203. 2005..We studied gray matter volume, ventricular-to-brain ratios (VBR), and number of WMH in patients with familial, pediatric BD compared with control subjects... - Antidepressants and psychostimulants in pediatric populations: is there an association with mania?Michelle Goldsmith
Stanford Pediatric Bipolar Disorders Program, Stanford University School of Medicine, Department of Psychiatry, 401 Quarry Road, Stanford, CA 94305, USA
Paediatr Drugs 13:225-43. 2011.... - Divalproex sodium for the treatment of PTSD and conduct disordered youth: a pilot randomized controlled clinical trialHans Steiner
Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
Child Psychiatry Hum Dev 38:183-93. 2007..Intent-to-treat analyses showed significant positive associations between receiving high dose of DVP CGI's. Parallel analyses comparing outcome by drug level achieved strengthened the results... - Baseline predictors of response to divalproex in conduct disorderKirti Saxena
Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305, USA
J Clin Psychiatry 66:1541-8. 2005.... - An open-label study of lamotrigine adjunct or monotherapy for the treatment of adolescents with bipolar depressionKiki Chang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
J Am Acad Child Adolesc Psychiatry 45:298-304. 2006..The authors wished to prospectively study the efficacy of lamotrigine as adjunctive or monotherapy in adolescents with bipolar disorder who were experiencing a depressive episode... - Decreased N-acetylaspartate in children with familial bipolar disorderKiki Chang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
Biol Psychiatry 53:1059-65. 2003.... - Reduced amygdalar gray matter volume in familial pediatric bipolar disorderKiki Chang
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5540, USA
J Am Acad Child Adolesc Psychiatry 44:565-73. 2005..We sought to study morphometric characteristics of these structures in pediatric subjects with familial BD compared with healthy controls... - Efficacy profiles of psychopharmacology: divalproex sodium in conduct disorderLeena A Khanzode
Division of Child Psychiatry and Child Development, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
Child Psychiatry Hum Dev 37:55-64. 2006..This is a rare clinical trial, which provides preliminary evidence for the different profiles of efficacy of medication treatment... - Will neuroimaging ever be used to diagnose pediatric bipolar disorder?Kiki Chang
Stanford University School of Medicine, CA 94305 5540, USA
Dev Psychopathol 18:1133-46. 2006.... - Increased subgenual cingulate cortex volume in pediatric bipolar disorder associated with mood stabilizer exposureMyles M Mitsunaga
Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
J Child Adolesc Psychopharmacol 21:149-55. 2011..We sought to study morphometric characteristics of the SGC in pediatric subjects with familial bipolar disorder (BD) compared with healthy controls... - Studies of offspring of parents with bipolar disorderKiki Chang
Pediatric Mood Disorders Clinic, Stanford University School of Medicine, Stanford, CA 94305, USA
Am J Med Genet C Semin Med Genet 123:26-35. 2003..The future holds promise for longitudinal studies of bipolar offspring incorporating all of these facets, including genetic analyses, to further elucidate the factors involved in the evolution of BD... - Challenges in the diagnosis and treatment of pediatric bipolar depressionKiki Chang
Pediatric Bipolar Disorders Program, Stanford University School of Medicine, Stanford, California 94305 5540, USA
Dialogues Clin Neurosci 11:73-80. 2009.... - Psychopharmacologic strategies for the treatment of aggression in juvenilesHans Steiner
Department of Psychiatry and Behavioral Sciences, Division of Child Psychiatry and Child Development, Stanford University School of Medicine, California 94503, USA
CNS Spectr 8:298-308. 2003.... - Adult bipolar disorder is continuous with pediatric bipolar disorderKiki Chang
Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Lucile Packard Children s Hospital, California 94305 5540, USA
Can J Psychiatry 52:418-25. 2007..Prospective studies incorporating phenomenological and biological assessment are needed to decisively address this issue... - Prevention of pediatric bipolar disorder: integration of neurobiological and psychosocial processesKiki Chang
Pediatric Bipolar Disorders Program, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA
Ann N Y Acad Sci 1094:235-47. 2006..Further research into the biologic and environmental mechanisms of BD development as well as controlled early intervention studies are needed to ameliorate this significant public health problem... - Divalproex sodium in the treatment of pediatric psychiatric disordersManasi Rana
Division of Child Psychiatry and Child Development, Department of Psychiatry and Behavioral Sciences, Stanford University, School of Medicine, 401 Quarry Road, Stanford, CA 94305 5719, USA
Expert Rev Neurother 5:165-76. 2005..In this drug profile, divalproex sodium and its uses in the pediatric population for psychiatric conditions are reviewed... - Attention and memory biases in the offspring of parents with bipolar disorder: indications from a pilot studyIan H Gotlib
Stanford University, Stanford, California 94305, USA
J Child Psychol Psychiatry 46:84-93. 2005..This study examined biases in the processing of emotional stimuli as a potential vulnerability marker of bipolar disorder... - Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents with bipolar disordersMina Hah
Department of Child and Adolescent Psychiatry at Stanford University, Stanford, California 94305 5719, USA
J Child Adolesc Psychopharmacol 15:996-1004. 2005..Adverse effects of atomoxetine treatment included sedation, nausea, and decreased appetite. These cases suggest that atomoxetine may be a safe and effective treatment for ADHD in conjunction with mood stabilizers in children with BD... - Bipolar offspring: a window into bipolar disorder evolutionKiki Chang
Division of Child and Adolescent Psychiatry, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
Biol Psychiatry 53:945-51. 2003.... - Treatment of aggression with risperidone in children and adolescents with bipolar disorder: a case seriesKirti Saxena
Department of Psychiatry, Stanford University, Palo Alto, CA 94305, USA
Bipolar Disord 8:405-10. 2006..To evaluate the effectiveness and safety of risperidone in children and adolescents with bipolar disorder characterized by aggression and mania, despite treatment with mood stabilizers...