Research Topics
| John R AdlerSummaryAffiliation: Stanford University Country: USA Publications
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Publications
Visual field preservation after multisession cyberknife radiosurgery for perioptic lesionsJohn R Adler
Department of Neurosurgery, Stanford University Medical School, Stanford, California, USA
Neurosurgery 59:244-54; discussion 244-54. 2006..The current retrospective study is intended to help address these shortcomings...
Toward an expanded view of radiosurgeryJohn R Adler
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5327, USA
Neurosurgery 55:1374-6. 2004..We therefore define radiosurgery as a procedure that involves the active participation of a surgeon and in which spatially accurate and highly conformal doses of radiation are targeted at well-defined structures with an ablative intent...
Nonisocentric radiosurgical rhizotomy for trigeminal neuralgiaJohn R Adler
Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
Neurosurgery 64:A84-90. 2009..In this single-institution prospective study, we evaluated clinical outcomes in a group of TN patients who underwent lesioning with seemingly optimized nonisocentric radiosurgical parameters...
Stereotactic radiosurgery for treatment of spinal metastases recurring in close proximity to previously irradiated spinal cordClara Y H Choi
Department of Neurosurgery, Stanford University Medical Center, CA, USA
Int J Radiat Oncol Biol Phys 78:499-506. 2010..As the spinal cord tolerance often precludes reirradiation with conventional techniques, local recurrence within a previously irradiated field presents a treatment challenge...
Stereotactic radiosurgery yields long-term control for benign intradural, extramedullary spinal tumorsSean Sachdev
Department of Radiation Oncology, Stanford University Cancer Center, Stanford, California, USA
Neurosurgery 69:533-9; discussion 539. 2011..Although a growing body of evidence supports its role in the treatment of malignant spinal lesions, a much less extensive dataset exists for treatment of benign spinal tumors...
Tolerance of the spinal cord to stereotactic radiosurgery: insights from hemangioblastomasMegan E Daly
Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 80:213-20. 2011..To evaluate spinal cord dose-volume effects, we present a retrospective review of stereotactic radiosurgery (SRS) treatments for spinal cord hemangioblastomas...
Frameless image guided robotic radiosurgery of arteriovenous malformation localized on spatially correlated digital subtraction and C-arm CT angiography imagesDimitre Hristov
Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305 5847, USA
J Neurointerv Surg 2:252-4. 2010..During delivery, a robotic linear accelerator tracked the target based on localization with frequent stereoscopic x-ray imaging. This case demonstrates that a frameless approach to AVM radiosurgery is possible...
Radiation therapy and CyberKnife radiosurgery in the management of craniopharyngiomasMarco Lee
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA
Neurosurg Focus 24:E4. 2008..The authors discuss the role of radiation therapy in the management of these tumors, and more specifically, the role of CyberKnife SRS...
Cyberknife stereotactic radiosurgery for treatment of atypical (WHO grade II) cranial meningiomasClara Y H Choi
Department of Neurosurgery, Stanford University Medical Center, Stanford, California, USA
Neurosurgery 67:1180-8. 2010..The optimal management of subtotally resected atypical meningiomas is unknown...
Cyberknife for brain metastases of malignant melanoma and renal cell carcinomaWendy Hara
Department of Radiation Oncology, Stanford University, Stanford Cancer Center, 875 Blake Wilbur Drive, Stanford, CA 94305 5847, USA
Neurosurgery 64:A26-32. 2009..To evaluate the efficacy of CyberKnife (Accuray, Inc., Sunnyvale, CA) stereotactic radiosurgery (SRS) for patients with brain metastases of malignant melanoma and renal cell carcinoma...
Management of pediatric intracranial arteriovenous malformations: experience with multimodality therapyTim E Darsaut
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5325, USA
Neurosurgery 69:540-56; discussion 556. 2011..Successful management of pediatric arteriovenous malformations (AVMs) often requires a balanced application of embolization, surgery, and radiosurgery...
Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinomaWendy Hara
Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 71:393-400. 2008..To determine long-term outcomes in patients receiving stereotactic radiotherapy (SRT) as a boost after external beam radiotherapy (EBRT) for locally advanced nasopharyngeal carcinoma (NPC)...
Survival following CyberKnife radiosurgery and hypofractionated radiotherapy for newly diagnosed glioblastoma multiformeJohn D Lipani
Department of Neurosurgery, Stanford University Medical Center, Stanford, California
Technol Cancer Res Treat 7:249-55. 2008..A larger prospective analysis that compares CyberKnife SRS and hypofractionated radiotherapy to focal EBRT is warranted...
Multimodality treatment of posterior fossa arteriovenous malformationsMichael E Kelly
Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305 5327, USA
J Neurosurg 108:1152-61. 2008..The authors present their experience with multimodality treatment of 76 posterior fossa AVMs, with an emphasis on Spetzler-Martin Grades III-V AVMs...
Preliminary visual field preservation after staged CyberKnife radiosurgery for perioptic lesionsChristopher J Pham
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
Neurosurgery 54:799-810; discussion 810-2. 2004..Ninety-one percent of patients retained their presurgical vision. Staged radiosurgery may be a safe and effective alternative to either surgery or fractionated radiotherapy for selected lesions adjacent to the optic apparatus...
Predictors of peritumoral edema after stereotactic radiosurgery of supratentorial meningiomasChirag G Patil
Department of Neurosurgery, Stanford University School of Medicine, Stanford Hospital, Stanford, California 94305, USA
Neurosurgery 63:435-40; discussion 440-2. 2008..Potential predictors of postradiosurgical peritumoral edema, including parasagittal tumor location, tumor size, and treatment dose, were evaluated...
Image-guided robotic radiosurgery for spinal metastasesIris C Gibbs
Department of Radiation Oncology, Stanford University, Stanford, CA 94305 5847, USA
Radiother Oncol 82:185-90. 2007..To determine the effectiveness and safety of image-guided robotic radiosurgery for spinal metastases...
Stereotactic radiosurgery of the postoperative resection cavity for brain metastasesScott G Soltys
Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA, USA
Int J Radiat Oncol Biol Phys 70:187-93. 2008..The purpose of this study was to analyze results of adjuvant stereotactic radiosurgery (SRS) targeted at resection cavities of brain metastases without whole-brain irradiation (WBI)...
Delayed radiation-induced myelopathy after spinal radiosurgeryIris C Gibbs
Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305 5847, USA
Neurosurgery 64:A67-72. 2009..We report a case series of 6 patients treated with radiosurgery who developed delayed myelopathy...
CyberKnife radiosurgical rhizotomy for the treatment of atypical trigeminal nerve painChirag G Patil
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5327, USA
Neurosurg Focus 23:E9. 2007..This study represents the first report of the treatment of atypical TN with frameless CyberKnife stereotactic radiosurgery (SRS)...
Radiosurgery for glomus jugulare tumorsMichael Lim
Department of Neurosurgery, Stanford University Medical Center, Stanford, CA 94305, USA
Technol Cancer Res Treat 6:419-23. 2007..Our results support radiosurgery as an effective and safe method of treatment for glomus jugulare tumors with low morbidity as evidenced by a larger number of patients and long term follow-up...
Patterns of patient movement during frameless image-guided radiosurgeryMartin J Murphy
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA
Int J Radiat Oncol Biol Phys 55:1400-8. 2003..We have analyzed the target position records for all of these cases to assess the frequency, magnitude, and case-by-case patterns of patient movement...
Stereotactic radiosurgical treatment of cranial and spinal hemangioblastomasJason M Moss
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA
Neurosurgery 65:79-85; discussion 85. 2009....
Technique for targeting arteriovenous malformations using frameless image-guided robotic radiosurgeryDimitre Hristov
Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305 5847, USA
Int J Radiat Oncol Biol Phys 79:1232-40. 2011....
Cyberknife stereotactic radiosurgical rhizotomy for trigeminal neuralgia: anatomic and morphological considerationsJohn D Borchers
Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
Neurosurgery 64:A91-5. 2009..To search for correlations between specific anatomic, geometric, and morphological properties of the trigeminal nerve and the success of radiosurgical treatment and elimination of facial hypesthesia as a complication...
Efficacy and safety of stereotactic radiosurgery for glomus jugulare tumorsMichael Lim
Department of Neurosurgery, Stanford University Medical Center, Stanford, California, USA
Neurosurg Focus 17:E11. 2004..CONCLUSIONS: The authors' findings continue to support radiosurgery as an effective and safe method of treatment for glomus jugulare tumors that results in low rates of morbidity...
Stereotactic radiosurgery of cranial nonvestibular schwannomas: results of single- and multisession radiosurgeryClara Y H Choi
Department of Neurosurgery, Stanford University Medical Center, Stanford, California, USA
Neurosurgery 68:1200-8; discussion 1208. 2011..Stereotactic radiosurgery (SRS) offers a non-invasive treatment alternative. The efficacy and safety of multi-session SRS of nonvestibular cranial schwannomas has not been well studied...
Multisession cyberknife stereotactic radiosurgery of large, benign cranial base tumors: preliminary studyFrancesco Tuniz
Department of Neurosurgery, Stanford University, Stanford, California 94305, USA
Neurosurgery 65:898-907; discussion 907. 2009..Sunnyvale, CA)...
Stereotactic radiosurgery using CT cisternography and non-isocentric planning for the treatment of trigeminal neuralgiaMichael Lim
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305-5327, USA
Comput Aided Surg 11:11-20. 2006..Further follow-up is needed to determine whether our method has advantages over the more commonly used procedure for radiosurgical trigeminal rhizotomy...
Multisession stereotactic radiosurgery for vestibular schwannomas: single-institution experience with 383 casesAke Hansasuta
Division of Neurological Surgery, Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Neurosurgery 69:1200-9. 2011..Single-session stereotactic radiosurgery (SRS) treatment of vestibular schwannomas results in excellent tumor control. It is not known whether functional outcomes can be improved by fractionating the treatment over multiple sessions...
Cyberknife radiosurgery for trigeminal schwannomasGordon T Sakamoto
Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
Neurosurgery 64:A14-8. 2009..The CyberKnife (Accuray, Inc., Sunnyvale, CA) is a frameless, robotic stereotactic radiosurgical system. In this series, we report our experience using the CyberKnife in the treatment of TS...
A study of the accuracy of cyberknife spinal radiosurgery using skeletal structure trackingAnthony K Ho
Department of Radiation Oncology, Stanford University Medical Center, Stanford, California 94305 5304, USA
Neurosurgery 60:ONS147-56; discussion ONS156. 2007..The Xsight system localizes spinal targets by direct reference to the adjacent vertebral elements. This study sought to measure the accuracy of Xsight spine tracking and provide a qualitative assessment of overall system performance...
The efficacy of linear accelerator stereotactic radiosurgery in treating glomus jugulare tumorsMichael Lim
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Dr, Room R-225, Stanford, CA 94305, USA
Technol Cancer Res Treat 2:261-5. 2003..Our results continue to support radiosurgery as a suitable form of treatment for glomus jugulare tumors as evidenced by results from this four and a half year follow-up...
CyberKnife rhizotomy for facetogenic back pain: a pilot studyGordon Li
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
Neurosurg Focus 23:E2. 2007..The authors used CyberKnife radiosurgery to denervate affected facet joints with the goal of obtaining a less invasive yet more thorough and durable antinociceptive rhizotomy...
Intensity-based 2D-3D spine image registration incorporating a single fiducial markerDaniel B Russakoff
Department of Computer Science, Stanford University, 300 Pasteur Drive, Stanford, CA 94305-5327, USA
Acad Radiol 12:37-50. 2005....
Pathogenesis and radiobiology of brain arteriovenous malformations: implications for risk stratification in natural history and posttreatment courseAchal S Achrol
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305 5487, USA
Neurosurg Focus 26:E9. 2009....
Irradiation of glomus jugulare tumors: a historical perspectiveGordon Li
Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305, USA
Neurosurg Focus 23:E13. 2007..In this article the authors discuss the history of radiation therapy for glomus jugulare tumors, focusing on recent radiosurgical results...
Foraminal nerve sheath tumors: intermediate follow-up after cyberknife radiosurgeryJudith A Murovic
Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305 5327, USA
Neurosurgery 64:A33-43. 2009..Sunnyvale, CA) radiosurgery at Stanford University Medical Center from 1999 to 2006...
Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinomaQuynh-Thu Le
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305-5302, USA
Int J Radiat Oncol Biol Phys 56:1046-54. 2003..CONCLUSION: STR boost after EBRT provided excellent local control in nasopharyngeal carcinoma patients. The incidence of late toxicity was acceptable. More effective systemic treatment is needed to achieve improved survival...
Efficacy and safety of CyberKnife radiosurgery for acromegalyBrian K Roberts
Department of Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
Pituitary 10:19-25. 2007..The aim of this study was to determine the efficacy and tolerability of CyberKnife stereotactic radiosurgery in acromegaly...
CyberKnife radiosurgery for idiopathic trigeminal neuralgiaMichael Lim
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
Neurosurg Focus 18:E9. 2005..The doses used for treatment were safe and effective. Higher prescribed doses were not associated with improvement in pain relief or recurrence rate. The hypesthesia rate was related to the length of the trigeminal nerve treated...
Staged stereotactic irradiation for acoustic neuromaSteven D Chang
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA
Neurosurgery 56:1254-61; discussion 1261-3. 2005..We hypothesize that such factors may further minimize injury of adjacent cranial nerves. In this retrospective study, we report our experience with staged radiosurgery for managing acoustic neuromas...
Visual field preservation after curative multi-modality treatment of occipital lobe arteriovenous malformationsJohn Sinclair
Department of Neurosurgery, The Stanford Stroke Center, Stanford University, Stanford, California 94305-5327, USA
Neurosurgery 57:655-67; discussion 655-67. 2005..CONCLUSION: Occipital AVMs can be safely cured using multimodality strategies with minimal risk to visual function despite the proximity of these lesions to the visual cortex and associated pathways...
Multisession CyberKnife radiosurgery for intramedullary spinal cord arteriovenous malformationsJohn Sinclair
Department of Neurosurgery, Stanford University, Stanford, California, USA
Neurosurgery 58:1081-9; discussion 1081-9. 2006..Additional experience is necessary to ascertain the optimal radiosurgical dose and ultimate efficacy of this technique...
Fast generation of digitally reconstructed radiographs using attenuation fields with application to 2D-3D image registrationDaniel B Russakoff
Department of Computer Science, Stanford University, Stanford, CA 94305 USA
IEEE Trans Med Imaging 24:1441-54. 2005..The registration accuracy and robustness of the two methods is virtually identical whereas the execution speed using AF-DRRs is an order of magnitude faster...
The 2009 devaluation of radiosurgery and its impact on the neurosurgery-radiation oncology partnershipM Peter Heilbrun
Department of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
J Neurosurg 113:10-5. 2010....
CyberKnife radiosurgery for benign intradural extramedullary spinal tumorsRobert L Dodd
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California 94305, USA
Neurosurgery 58:674-85; discussion 674-85. 2006..The present study demonstrates that CyberKnife radiosurgical ablation of such tumors is technically feasible and associated with low morbidity...
CyberKnife radiosurgery for lesions of the foramen magnumSamuel H Cheshier
Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA
Technol Cancer Res Treat 6:329-36. 2007..5 yrs and 2.5 yrs out from treatment). Cyberknife radiosurgery can be an effective treatment for many foramen magnum lesions...
Cyberknife targeting the pterygopalatine ganglion for the treatment of chronic cluster headachesShivanand P Lad
Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA
Neurosurgery 60:E580-1; discussioin E581. 2007..We evaluated the treatment of medically refractory CH with CyberKnife (Accuray, Inc., Sunnyvale, CA) stereotactic radiosurgery targeting the pterygopalatine ganglion...
Trigeminal neuralgia treatment dosimetry of the CyberknifeAnthony Ho
Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA
Med Dosim 37:42-6. 2012..Monte Carlo calculation algorithm may be useful in deriving the dose necessary for trigeminal neuralgia treatments...
CyberKnife radiosurgery for extremity schwannomas: technical note and case reportMichael Lim
Department of Neurosurgery, Stanford University Hospital, Stanford, CA 94305-5327, USA
Stereotact Funct Neurosurg 84:60-3. 2006..Although this experience is still very preliminary, it represents the first published description of a peripheral nerve sheath tumor being treated with stereotactic radiosurgery...
Image guided stereotactic radiosurgery for lesions in proximity to the anterior visual pathways: a preliminary reportVivek K Mehta
Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305, USA
Technol Cancer Res Treat 1:173-80. 2002..Fractionated SRS using the CyberKnife is technically feasible and may decrease the risk of optic neuropathy. Greater patient accrual and longer follow up will be necessary to further determine the clinical benefit of this approach...
CyberKnife radiotherapy for localized prostate cancer: rationale and technical feasibilityChristopher R King
Department of Radiation Oncology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
Technol Cancer Res Treat 2:25-30. 2003..These capabilities are essential if one contemplates hypo-fractionated regimens with large dose-per-fraction sizes (>5Gy to 10Gy) and dose-escalation...
Surgical guidance now and in the future: the next generation of instrumentationJohn R Adler
Departments of Neurosurgery and Radiation Oncology, Stanford University Medical Center, Stanford, California, USA
Clin Neurosurg 49:105-14. 2002
Accuray, incorporated: a neurosurgical business case studyJohn R Adler
Department of Neurosurgery, Stanford University School of Medicine, California, USA
Clin Neurosurg 52:87-96. 2005
The use of TLD and Gafchromic film to assure submillimeter accuracy for image-guided radiosurgeryAnthony K Ho
Theresa Po Cyberknife Center, Hong Kong Adventist Hospital, Hong Kong
Med Dosim 33:36-41. 2008..This approach, which is routinely in used at our institution, has repeatedly confirmed the submillimeter targeting accuracy of our Cyberknife...
An anthropomorphic phantom study of the accuracy of Cyberknife spinal radiosurgeryCheng Yu
Department of Radiation Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033 0804, USA
Neurosurgery 55:1138-49. 2004..Sunnyvale, CA) uses implanted stainless steel fiducials. The purpose of this study was to evaluate the total system for clinically relevant accuracy of this approach...
Image-guided radiosurgical ablation of intra- and extra-cranial lesionsPantaleo Romanelli
Department of Neurosurgery, Neuromed IRCCS, Pozzilli, IS, Italy
Technol Cancer Res Treat 5:421-8. 2006..In this review we will describe the technical features of frameless SRS systems and briefly review their application to treating intracranial and extracranial lesions, focusing in particular on spinal lesions...
Treatment of intraorbital lesions using the Accuray CyberKnife systemMarc J Hirschbein
Department of Ophthalmology, Krieger Eye Institute, Sinai Hospital of Baltimore, Baltimore, MD, USA
Orbit 27:97-105. 2008..The goal of this study was to better understand the safety and efficacy of CyberKnife image-guided radiosurgery for lesions immediately adjacent to the optic nerves...
Technology Insight: image-guided robotic radiosurgery--a new approach for noninvasive ablation of spinal lesionsPantaleo Romanelli
Department of Neurosurgery, IRCCS Neuromed, Pozzilli, Italy
Nat Clin Pract Oncol 5:405-14. 2008..Although spinal radiosurgery is not yet widely practiced, the benefits of this new therapeutic approach are likely to encourage its widespread adoption in coming years...
Resampling: an optimization method for inverse planning in robotic radiosurgeryAchim Schweikard
Institute of Robotics and Cognitive Systems, University of Lubeck, SH 23538, Germany
Med Phys 33:4005-11. 2006..Experimental results indicate that the planning approach efficiently finds acceptable plans and that resampling can further improve its efficiency...
Cyberknife radiosurgery for trigeminal neuralgia treatment: a preliminary multicenter experienceAlan T Villavicencio
Boulder Neurosurgical Associates, Boulder, Colorado 80304, USA
Neurosurgery 62:647-55; discussion 647-55. 2008..Radiosurgery has gained acceptance as a treatment option for trigeminal neuralgia. We report our preliminary multicenter experience treating trigeminal neuralgia with the CyberKnife (Accuray, Inc., Sunnyvale, CA)...
Stereotactic radiosurgery--an organized neurosurgery-sanctioned definitionGene H Barnett
Taussig Cancer Center, Brain Tumor Institute, Cleveland, Ohio 44195, USA
J Neurosurg 106:1-5. 2007
