Laura Murphy

Summary

Affiliation: Southern Illinois University School of Medicine
Country: USA

Publications

  1. ncbi Ginseng, sex behavior, and nitric oxide
    Laura L Murphy
    Department of Physiology, Southern Illinois University, School of Medicine, Carbondale, Illinois 62901, USA
    Ann N Y Acad Sci 962:372-7. 2002
  2. ncbi Extraction-dependent effects of American ginseng (Panax quinquefolium) on human breast cancer cell proliferation and estrogen receptor activation
    Mandy L King
    Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois 62901-6523, USA
    Integr Cancer Ther 5:236-43. 2006
  3. ncbi American ginseng (Panax quinquefolius L.) extract alters mitogen-activated protein kinase cell signaling and inhibits proliferation of MCF-7 cells
    Mandy L King
    Department of Physiology, Southern Illinois University School of Medicine Carbondale, IL 62902 6523, USA
    J Exp Ther Oncol 6:147-55. 2007
  4. ncbi American Ginseng inhibits induced COX-2 and NFKB activation in breast cancer cells
    Elizabeth A Peralta
    Department of Surgery, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9638, USA
    J Surg Res 157:261-7. 2009
  5. ncbi The influence of lead and arsenite on the inhibition of human breast cancer MCF-7 cell proliferation by American ginseng root (Panax quinquefolius L.)
    Rebecca Corbit
    Department of Plant Biology, Southern Illinois University Carbondale, Carbondale, IL 62901, USA
    Life Sci 78:1336-40. 2006
  6. ncbi Simplified extraction of ginsenosides from American ginseng (Panax quinquefolius L.) for high-performance liquid chromatography-ultraviolet analysis
    Rebecca M Corbit
    Department of Plant Biology, Southern Illinois University Carbondale, Carbondale, Illinois 62901, USA
    J Agric Food Chem 53:9867-73. 2005

Research Grants

  1. CANNABINOIDS AND THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    Laura Murphy; Fiscal Year: 2002
  2. Adjuvant Ginseng Use During Breast Cancer Drug Therapy
    Laura Murphy; Fiscal Year: 2005
  3. Anti-Cancer Ginsenosides: Their Interactions and Mechanisms of Action
    Laura Murphy; Fiscal Year: 2007

Collaborators

  • Elizabeth A Peralta
  • Mandy L King
  • Rebecca Corbit
  • Rebecca M Corbit
  • Stuart R Adler
  • Stephen Ebbs
  • Jorge F S Ferreira
  • Stephen D Ebbs

Detail Information

Publications6

  1. ncbi Ginseng, sex behavior, and nitric oxide
    Laura L Murphy
    Department of Physiology, Southern Illinois University, School of Medicine, Carbondale, Illinois 62901, USA
    Ann N Y Acad Sci 962:372-7. 2002
    ..Thus, animal studies lend growing support for the use of ginseng in the treatment of sexual dysfunction and provide increasing evidence for a role of nitric oxide in the mechanism of ginsenoside action...
  2. ncbi Extraction-dependent effects of American ginseng (Panax quinquefolium) on human breast cancer cell proliferation and estrogen receptor activation
    Mandy L King
    Department of Physiology, Southern Illinois University School of Medicine, Carbondale, Illinois 62901-6523, USA
    Integr Cancer Ther 5:236-43. 2006
    ..Thus, discrepant results between different laboratories may be due to the type of GE being analyzed for estrogenic activity...
  3. ncbi American ginseng (Panax quinquefolius L.) extract alters mitogen-activated protein kinase cell signaling and inhibits proliferation of MCF-7 cells
    Mandy L King
    Department of Physiology, Southern Illinois University School of Medicine Carbondale, IL 62902 6523, USA
    J Exp Ther Oncol 6:147-55. 2007
    ..This novel mechanism has implications in the potential prevention and treatment of breast cancer...
  4. ncbi American Ginseng inhibits induced COX-2 and NFKB activation in breast cancer cells
    Elizabeth A Peralta
    Department of Surgery, Southern Illinois University School of Medicine, Springfield, Illinois 62794 9638, USA
    J Surg Res 157:261-7. 2009
    ..We hypothesized that AG extract decreases proliferation of human breast cancer cells via an anti-inflammatory effect applicable to the prevention of breast and other cancers...
  5. ncbi The influence of lead and arsenite on the inhibition of human breast cancer MCF-7 cell proliferation by American ginseng root (Panax quinquefolius L.)
    Rebecca Corbit
    Department of Plant Biology, Southern Illinois University Carbondale, Carbondale, IL 62901, USA
    Life Sci 78:1336-40. 2006
    ..These results suggest that contaminant heavy metals, some of which have been detected in ginseng root extracts or commercial ginseng preparations, may alter the biological activity of ginseng...
  6. ncbi Simplified extraction of ginsenosides from American ginseng (Panax quinquefolius L.) for high-performance liquid chromatography-ultraviolet analysis
    Rebecca M Corbit
    Department of Plant Biology, Southern Illinois University Carbondale, Carbondale, Illinois 62901, USA
    J Agric Food Chem 53:9867-73. 2005
    ..All methods used one filtration step, omitted time-consuming cleanup, but maintained clear peak resolution by HPLC, and can be used for quantitative screening of ginsenosides from roots and commercial ginseng preparations...

Research Grants6

  1. CANNABINOIDS AND THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    Laura Murphy; Fiscal Year: 2002
    ..abstract_text> ..
  2. Adjuvant Ginseng Use During Breast Cancer Drug Therapy
    Laura Murphy; Fiscal Year: 2005
    ....
  3. Anti-Cancer Ginsenosides: Their Interactions and Mechanisms of Action
    Laura Murphy; Fiscal Year: 2007
    ....