Jairam R Palamanda

Summary

Affiliation: Schering-Plough Research Institute
Country: USA

Publications

  1. ncbi High-throughput evaluation of CYP1A1 and 2B1 induction in rat liver slices using a semi-automated system
    Jairam R Palamanda
    Schering Plough Research Institute, Kenilworth, New Jersey 07033, USA
    Drug Metab Lett 3:108-14. 2009
  2. ncbi Evaluation of CYP1A1 and CYP2B1/2 m-RNA induction in rat liver slices using the NanoString technology: a novel tool for drug discovery lead optimization
    Jairam R Palamanda
    Schering Plough Research Institute, Kenilworth, New Jersey 07033, USA
    Drug Metab Lett 3:171-5. 2009
  3. ncbi Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR
    Federico M Goodsaid
    Department of Genetic and Molecular Toxicology, Schering Plough Research Institute, PO Box 32, Lafayette, New Jersey 07848, USA
    Pharm Res 20:1373-80. 2003

Detail Information

Publications3

  1. ncbi High-throughput evaluation of CYP1A1 and 2B1 induction in rat liver slices using a semi-automated system
    Jairam R Palamanda
    Schering Plough Research Institute, Kenilworth, New Jersey 07033, USA
    Drug Metab Lett 3:108-14. 2009
    ..The increase in throughput allowed the quick development of structure-induction relationships (SIR's) for multiple drug discovery programs in a facile manner...
  2. ncbi Evaluation of CYP1A1 and CYP2B1/2 m-RNA induction in rat liver slices using the NanoString technology: a novel tool for drug discovery lead optimization
    Jairam R Palamanda
    Schering Plough Research Institute, Kenilworth, New Jersey 07033, USA
    Drug Metab Lett 3:171-5. 2009
    ..85). Therefore, NanoString provides an additional new technology to evaluate the induction of CYP1A1 and 2B1/2, as well as potentially other enzymes or transporters in rat liver slices...
  3. ncbi Assessment of temporal biochemical and gene transcription changes in rat liver cytochrome P450: utility of real-time quantitative RT-PCR
    Federico M Goodsaid
    Department of Genetic and Molecular Toxicology, Schering Plough Research Institute, PO Box 32, Lafayette, New Jersey 07848, USA
    Pharm Res 20:1373-80. 2003
    ....