Research Topics
| Jennifer D ThomasSummaryAffiliation: San Diego State University Country: USA Publications
Research Grants
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Detail Information
Publications
Alcohol-induced Purkinje cell loss depends on developmental timing of alcohol exposure and correlates with motor performanceJ D Thomas
Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA
Brain Res Dev Brain Res 105:159-66. 1998....- Timing accuracy and variability in children with prenatal exposure to alcoholTara S Wass
Department of Child and Family Studies, University of Tennessee, Knoxville 37996, USA
Alcohol Clin Exp Res 26:1887-96. 2002..The present study examined performance on two types of timing tasks to determine the extent to which prenatal alcohol exposure affects perception, movement planning, and movement execution during tasks that require temporal processing... - Voluntary exercise influences behavioral development in rats exposed to alcohol during the neonatal brain growth spurtJennifer D Thomas
Department of Psychology, Center for Behavioral Teratology, San Diego State University, CA, USA
Behav Neurosci 122:1264-73. 2008..In sum, these data suggest that exercise may increase neuronal plasticity not only in controls, but also in subjects exposed to alcohol during development... - Choline supplementation following third-trimester-equivalent alcohol exposure attenuates behavioral alterations in ratsJennifer D Thomas
Department of Psychology, San Diego State University, San Diego, CA 92120, USA
Behav Neurosci 121:120-30. 2007..Moreover, the data suggest that early dietary interventions may reduce the severity of some fetal alcohol effects, even when administered after birth... - Proceedings of the 2008 annual meeting of the Fetal Alcohol Spectrum Disorders Study GroupJennifer D Thomas
Department of Psychology, San Diego State University, San Diego, CA 92120, USA
Alcohol 43:333-9. 2009..Presentations were also made by recipients of the Student Research Merit award and Rosett award... - Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in ratsJennifer D Thomas
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, CA 92120, USA
Neurotoxicol Teratol 31:303-11. 2009..These data indicate early dietary supplements may reduce the severity of some fetal alcohol effects, findings with important implications for children of women who drink alcohol during pregnancy... - Administration of eliprodil during ethanol withdrawal in the neonatal rat attenuates ethanol-induced learning deficitsJ D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Ct, Ste 209, San Diego, CA 92120, USA
Psychopharmacology (Berl) 175:189-95. 2004..Eliprodil is a more selective NMDA receptor antagonist that acts at the polyamine modulatory site of NMDA receptors... - Perinatal choline supplementation does not mitigate motor coordination deficits associated with neonatal alcohol exposure in ratsJennifer D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Ct Ste 209, San Diego, CA 92120, USA
Neurotoxicol Teratol 26:223-9. 2004.... - Perinatal choline supplementation attenuates behavioral alterations associated with neonatal alcohol exposure in ratsJennifer D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, Suite 209, 6363 Alvarado Court, San Diego 92120, USA
Neurotoxicol Teratol 26:35-45. 2004..These data suggest that early dietary interventions may reduce the severity of fetal alcohol effects... - Differential vulnerability to motor deficits in second replicate HAS and LAS rats following neonatal alcohol exposureJ D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Ct Suite 209, San Diego, CA 92120, USA
Pharmacol Biochem Behav 75:17-24. 2003..They also provide evidence that genetic factors play a role in fetal alcohol effects and suggest that phenotypic markers may indicate individuals at high risk for some fetal alcohol effects... - Neonatal choline supplementation ameliorates the effects of prenatal alcohol exposure on a discrimination learning task in ratsJ D Thomas
Center for Behavioral Teratology, San Diego State University, Suite 209, 6363 Alvarado Ct, San Diego, CA 92120, USA
Neurotoxicol Teratol 22:703-11. 2000..These data suggest that early dietary interventions may reduce the severity of fetal alcohol effects... - MK-801 can exacerbate or attenuate behavioral alterations associated with neonatal alcohol exposure in the rat, depending on the timing of administrationJ D Thomas
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 25:764-73. 2001..In the present study, we altered the timing of MK-801 delivery in relation to the last alcohol dose to determine if its protective effects were specific to the ethanol withdrawal phase... - Administration of low doses of MK-801 during ethanol withdrawal in the developing rat pup attenuates alcohol's teratogenic effectsJennifer D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Court, Suite 209, San Diego, CA 92120, USA
Alcohol Clin Exp Res 26:1307-13. 2002..This study examined the dose dependency of MK-801's ability to mitigate ethanol's teratogenic effects... - Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in ratsJennifer D Thomas
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6363 Alvarado Court, San Diego, CA 92120, USA
Birth Defects Res A Clin Mol Teratol 88:827-37. 2010..The present study examined whether choline supplementation during prenatal ethanol treatment could mitigate the adverse effects of ethanol on behavioral development... - Choline supplementation attenuates learning deficits associated with neonatal alcohol exposure in the rat: effects of varying the timing of choline administrationS Hunter Ryan
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, CA 92120, USA
Brain Res 1237:91-100. 2008..Importantly, these findings indicate that choline supplementation may effectively reduce some alcohol-related learning impairments, even when administered in later childhood... - Administration of memantine during ethanol withdrawal in neonatal rats: effects on long-term ethanol-induced motor incoordination and cerebellar Purkinje cell lossNirelia M Idrus
Department of Psychology, Center for Behavioral Teratology, San Diego State University, California 92120, USA
Alcohol Clin Exp Res 35:355-64. 2011.... - The effects of a single memantine treatment on behavioral alterations associated with binge alcohol exposure in neonatal ratsNirelia M Idrus
Center for Behavioral Teratology, Department of Psychology, San Diego State University, 6330 Alvarado Ct, Ste 100, San Diego, CA 92120, USA
Neurotoxicol Teratol 33:444-50. 2011..The current study examined whether memantine, an NMDA receptor antagonist and a drug used clinically in Alzheimer's patients, would attenuate impairments associated with binge ethanol exposure in neonatal rats... - Insulin-like growth factor-I mitigates motor coordination deficits associated with neonatal alcohol exposure in ratsNancy N H McGough
Department of Psychology, San Diego State University, San Diego, CA 92120, USA
Neurotoxicol Teratol 31:40-8. 2009..These data indicate that IGF-I may be a potential treatment for some of ethanol's damaging effects, a finding that has important implications for children of women who drink alcohol during pregnancy... - Motor response selection in children with fetal alcohol spectrum disordersRoger W Simmons
Motor Control Laboratory, Department of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA 92182, USA
Neurotoxicol Teratol 28:278-85. 2006..It was concluded that FASD adolescents require additional time to process increasing amount of information, but that the time required for motor response selection is not delayed relative to control group performance... - Motor response programming and movement time in children with heavy prenatal alcohol exposureRoger W Simmons
San Diego State University, CA 92182, USA
Alcohol 44:371-8. 2010..The observed results indicate children with FAS experience deficits in response programming and movement time production... - Artificial rearingHector D Dominguez
Center for Behavioral Teratology, Department of Psychology, San Diego State University, San Diego, CA, USA
Methods Mol Biol 447:85-100. 2008..This chapter provides a description of the methods needed for this administrative technique, including preparation of the artificial rearing environment, gastrostomy surgery, and care of artificially reared rat pups... - Alterations in circadian rhythm phase shifting ability in rats following ethanol exposure during the third trimester brain growth spurtHiromi Sakata-Haga
Department of Psychology, Center for Behavioral Teratology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 30:899-907. 2006..Disruptions in circadian regulation may cause abnormal behavioral rhythmicity, such as disrupted sleep and feeding patterns, as seen in individuals prenatally exposed to ethanol... - Neurophysiologic consequences of neonatal ethanol exposure in the ratCraig J Slawecki
The Scripps Research Institute, Department of Neuropharmacology, CVN 14, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Alcohol 34:187-96. 2004..This neurobehavioral profile in the rat is consistent with clinical observations of attention deficits and hyperactivity in children exposed to ethanol during prenatal development... - Fetal alcohol effects: mechanisms and treatmentE P Riley
Center for Behavioral Teratology EPR, JDT, Department of Psychology, San Diego State University, San Diego, California 92120, USA
Alcohol Clin Exp Res 25:110S-116S. 2001..Hungund; and (4) Fetal alcohol exposure alters the wiring of serotonin system at mid-gestation, by F. Zhou, Y. Sari, Charles Goodlett, T. Powrozek, and Ting-Kai Li... - Children with heavy prenatal alcohol exposure exhibit deficits when regulating isometric forceRoger W Simmons
Motor Control Laboratory, School of Exercise and Nutritional Sciences, San Diego State University, San Diego, California 92182, USA
Alcohol Clin Exp Res 36:302-9. 2012..e., constant) force is an essential component of performing everyday functional tasks, yet no studies have investigated how this type of force is regulated in children with confirmed histories of heavy prenatal alcohol exposure... - Fractionated simple and choice reaction time in children with prenatal exposure to alcoholRoger W Simmons
Motor Control Laboratory, Department of Exercise and Nutritional Sciences, San Diego State University, San Diego, California 92182, USA
Alcohol Clin Exp Res 26:1412-9. 2002..Each RT interval was fractionated into premotor and motor components to assess the central processing of stimulus information and peripheral motor unit recruitment, respectively... - Proceedings of the 2006 annual meeting of the Fetal Alcohol Spectrum Disorders Study GroupDaniel J Bonthius
Department of Pediatrics, University of Iowa College of Medicine, Iowa City, IA, USA
Alcohol 40:61-5. 2006....
Research Grants
- Fetal Alcohol Effects and Choline InterventionJennifer D Thomas; Fiscal Year: 2010..Importantly, choline supplementation may serve as a relatively safe and effective treatment that could be administered after birth in humans. ..
- Fetal Alcohol Effects and Choline InterventionJennifer Thomas; Fiscal Year: 2007..Importantly, choline supplementation may serve as a relatively safe and effective treatment that could be administered after birth in humans. ..
- Fetal Alcohol Effects and Choline InterventionJennifer Thomas; Fiscal Year: 2003..The identification of an effective dietary intervention has important implications for children exposed to alcohol prenatally. ..