Research Topics
| Sarah L GeorgeSummaryAffiliation: Saint Louis University Country: USA Publications
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Detail Information
Publications
The GB virus C (GBV-C) NS3 serine protease inhibits HIV-1 replication in a CD4+ T lymphocyte cell line without decreasing HIV receptor expressionSarah L George
Division of Infectious Diseases, Department of Internal Medicine, St Louis University, St Louis, Missouri, United States of America
PLoS ONE 7:e30653. 2012..Two GBV-C proteins, NS5A and E2, have been shown previously to inhibit HIV replication in vitro. We investigated whether the GBV-C NS3 serine protease affects HIV replication...- What you need to know about GB virus CSarah L George
Division of Infectious Diseases, Saint Louis University School of Medicine, FDT 8N, 3635 Vista Avenue, St Louis, MO 63110, USA
Curr Gastroenterol Rep 7:54-62. 2005..GBV-C E2 protein in serum has also been associated with prolonged survival in HIV infection; recent evidence indicates that GBV-C E2 protein may neutralize HIV infection in vitro... - GB virus C replicates in primary T and B lymphocytesSarah L George
Research Service and Department of Internal Medicine, Saint Louis University Hospital and St Louis Veterans Affairs Medical Center, MO 63110, USA
J Infect Dis 193:451-4. 2006.... - Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patientsSarah L George
Department of Internal Medicine, Division of Gastroenterology, Saint Louis University Liver Center, St Louis, MO, USA
Hepatology 49:729-38. 2009..A minority of patients had normal or nearly normal liver tissue on long-term follow-up biopsy. Patients with cirrhosis pretreatment are at a low but real risk of HCC after SVR... - Hepatitis C virus viremia in HIV-infected individuals with negative HCV antibody testsSarah L George
Department of Internal Medicine, Iowa City Veterans Administration Medical Center, University of Iowa, College of Medicine, 52242, USA
J Acquir Immune Defic Syndr 31:154-62. 2002.... - Inhibition of HIV-1 replication by GB virus C infection through increases in RANTES, MIP-1alpha, MIP-1beta, and SDF-1Jinhua Xiang
Research Service and Department of Internal Medicine, Iowa City VA Medical Center and University of Iowa, Iowa City, IA, USA
Lancet 363:2040-6. 2004..This study provides insight into the epidemiological association between GBV-C infection and longer survival in HIV-infected individuals... - Recombinant hepatitis C virus-like particles expressed by baculovirus: utility in cell-binding and antibody detection assaysJinhua Xiang
Department of Internal Medicine, Iowa City Veterans Administration Medical Center, Iowa City, Iowa, USA
J Med Virol 68:537-43. 2002..In addition, HCV VLPs seem useful for evaluating HCV-cell interactions... - Clinical isolates of GB virus type C vary in their ability to persist and replicate in peripheral blood mononuclear cell culturesSarah L George
Departments of Internal Medicine and Research, Iowa City VA Medical Center, University of Iowa, and the Helen C. Levitt Center for Viral Pathogenesis, Iowa City, IA 52242, USA
Virology 316:191-201. 2003..Since GBV-C appears to inhibit HIV replication in a coinfection model, these studies should facilitate determination of the mechanism of this interaction... - Persistent GB virus C infection is associated with decreased HIV-1 disease progression in the Amsterdam Cohort StudySarah L George
J Infect Dis 191:2156-7; author reply 2158-60. 2005