Research Topics
Genomes and Genes | Yueming TangSummaryAffiliation: Rush University Medical Center Country: USA Publications
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Publications
New molecular insights into inflammatory bowel disease-induced diarrheaYueming Tang
Department of Internal Medicine, Division of Digestive Disease and Nutrition, Rush University Medical Center, Chicago, IL 60612, USA
Expert Rev Gastroenterol Hepatol 5:615-25. 2011....
Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver diseaseYueming Tang
Division of Digestive Disease and Nutrition, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA
Alcohol Clin Exp Res 32:355-64. 2008..The aims of our study were: (i) to investigate the effect of alcohol on miRNA-212 (miR-212) and on expression of its predicted target gene, ZO-1, (ii) to study the potential role of miR-212 in the pathophysiology of ALD in man...
Sleep deprivation worsens inflammation and delays recovery in a mouse model of colitisYueming Tang
Department of Internal Medicine, Division of Digestive Disease and Nutrition, Rush University Medical Center, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
Sleep Med 10:597-603. 2009....
Epithelial NF-kappaB enhances transmucosal fluid movement by altering tight junction protein composition after T cell activationYueming Tang
Division of Gastroenterology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Am J Pathol 176:158-67. 2010..Epithelial NF-kappaB activation induced by mucosal T cells, therefore, actively plays a role in opening paracellular spaces to promote transmucosal fluid effux into the intestinal lumen...
Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damageYueming Tang
Division of Digestive Disease and Nutrition, Department of Internal Medicine, Rush University, Chicago, IL, USA
J Pharmacol Exp Ther 329:952-8. 2009..This study suggests that oats may be a useful therapeutic agent--a nutraceutical--for the prevention of alcohol-induced oxidative stress and organ dysfunction...
Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeabilityChristopher B Forsyth
Department of Internal Medicine, Section of Gastroenterology, Rush University Medical Center, Chicago, Illinois 60612, USA
Alcohol Clin Exp Res 35:1635-43. 2011..As activated Snail disrupts tight junctional proteins, we hypothesized that activation of Snail by iNOS might be one of the key signaling pathways mediating alcohol-stimulated intestinal epithelial cell hyperpermeability...
Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitisChristopher B Forsyth
Department of Internal Medicine, Division of Digestive Diseases and Nutrition, and Rush University Medical Center, 1725 W Harrison, Suite 206, Chicago, IL 60612, USA
Alcohol 43:163-72. 2009..Our study provides a scientific rationale to test probiotics for treatment and/or prevention of alcoholic liver disease in man...
Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cellsChristopher B Forsyth
Department of Internal Medicine, Section of Gastroenterology, Rush University Medical Center, Chicago, Illinois, USA
Alcohol Clin Exp Res 34:19-31. 2010....
Nitric oxide-mediated intestinal injury is required for alcohol-induced gut leakiness and liver damageYueming Tang
Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University, Chicago, Illinois, USA
Alcohol Clin Exp Res 33:1220-30. 2009..We hypothesized that iNOS inhibitors [NG-nitro-l-arginine methyl ester (l-NAME), l-N(6)-(1-iminoethyl)-lysine (l-NIL)] in vivo will inhibit the above cascade and liver injury in an animal model of alcoholic steatohepatitis (ASH)...
Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivoDaniel R Clayburgh
Department of Pathology, The University of Chicago, Chicago, Illinois, USA
J Clin Invest 115:2702-15. 2005..The data also indicate that inhibition of epithelial MLCK may be an effective non-immunosuppressive therapy for treatment of immune-mediated intestinal disease...
Anti-interferon-inducible chemokine, CXCL10, reduces colitis by impairing T helper-1 induction and recruitment in miceJae Geun Hyun
Department of Internal Medicine, Division of Gastroenterology, Northwestern University School of Medicine, Chicago, Illinois 60611, USA
Inflamm Bowel Dis 11:799-805. 2005....
Role of intestinal circadian genes in alcohol-induced gut leakinessGarth Swanson
Department of Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, 1725 W Harrison, Chicago, IL 60612, USA
Alcohol Clin Exp Res 35:1305-14. 2011....
IP-10-induced recruitment of CXCR3 host T cells is required for small bowel allograft rejectionZheng Zhang
Department of Surgery, Division of Organ Transplantation, Northwesern University Medical School, Chicago, Illinois 60611, USA
Gastroenterology 126:809-18. 2004..However, their role in small-bowel allograft rejection has not been defined. The aim of this study was to examine the roles of type 1 helper T-cell chemokines in small-bowel allograft rejection...
c-Myc sensitization to oxygen deprivation-induced cell death is dependent on Bax/Bak, but is independent of p53 and hypoxia-inducible factor-1Joslyn K Brunelle
Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611 3010, USA
J Biol Chem 279:4305-12. 2004..Thus, oxygen deprivation-induced cell death in fibroblasts with deregulated expression of c-Myc is independent of p53 or HIF-1 status, but is dependent on the Bcl-2 family member Bax or Bak to initiate mitochondrial dependent cell death...
