Research Topics
Species | Swati A KulkarniSummaryAffiliation: Roswell Park Cancer Institute Country: USA Publications
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Detail Information
Publications
TLE3 as a candidate biomarker of response to taxane therapySwati A Kulkarni
Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Breast Cancer Res 11:R17. 2009..The addition of taxanes (Ts) to chemotherapeutic regimens has not demonstrated a consistent benefit in early-stage breast cancer. To date, no clinically relevant biomarkers that predict T response have been identified...- The expression of TRMT2A, a novel cell cycle regulated protein, identifies a subset of breast cancer patients with HER2 over-expression that are at an increased risk of recurrenceDavid G Hicks
Clarient Inc, Aliso Veijo, California, USA
BMC Cancer 10:108. 2010..Furthermore, the small but established risk of cardiac morbidity with trastuzumab therapy compels efforts towards the identification of biomarkers that might help stratify patients... - HER2-positive early breast cancer and trastuzumab: a surgeon's perspectiveSwati Kulkarni
Department of Surgical Oncology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Ann Surg Oncol 15:1677-88. 2008..If trastuzumab is approved for use in neoadjuvant regimens, the need for surgeons to be well informed about the appropriate use of this particular agent will become even more important... - COX-2 and PPARgamma expression are potential markers of recurrence risk in mammary duct carcinoma in-situSwati Kulkarni
Lynn Sage Breast Center and Feinberg School of Medicine of Northwestern University, Chicago USA
BMC Cancer 8:36. 2008..We performed a case-control study to identify protein markers of local recurrence risk in DCIS... - Effect of delayed formalin fixation on estrogen and progesterone receptors in breast cancer: a study of three different clonesJingxin Qiu
Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Am J Clin Pathol 134:813-9. 2010..03). Based on our findings, it appears that regardless of the antibody clones evaluated, DFF has a negative effect on hormone receptors... - HER2+ breast cancer: review of biologic relevance and optimal use of diagnostic toolsDavid G Hicks
Department of Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Am J Clin Pathol 129:263-73. 2008..Rigorous quality control and standardization of the testing process, from the handling of tissue samples to interpretation and reporting of results, are essential for achieving accurate and reproducible assay results... - Modified Alcian blue enhances the intraoperative diagnosis of sentinel lymph node metastasis in invasive lobular carcinoma: a prospective studyThaer Khoury
Department of Pathology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
Arch Pathol Lab Med 134:1513-9. 2010..The sensitivity of an intraoperative diagnosis of sentinel lymph node metastasis of invasive lobular carcinoma using conventional staining is low... - Delay to formalin fixation effect on breast biomarkersThaer Khoury
Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
Mod Pathol 22:1457-67. 2009..03). To avoid delay to formalin fixation as a factor negatively affecting on breast biomarkers, we recommend not to delay formalin fixation for more than 1 h and not to store specimens overnight... - Dietary lignan intakes and risk of breast cancer by tumor estrogen receptor statusSusan E McCann
Department of Epidemiology, Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, NY, USA
Breast Cancer Res Treat 99:309-11. 2006.... - Dietary intakes of total and specific lignans are associated with clinical breast tumor characteristicsSusan E McCann
Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA
J Nutr 142:91-8. 2012..Future investigations are warranted to explore the strong associations observed with ER(-) cancer in premenopausal women... - Trastuzumab as adjuvant therapy for early breast cancer: the importance of accurate human epidermal growth factor receptor 2 testingDavid G Hicks
Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY 14642, USA
Arch Pathol Lab Med 132:1008-15. 2008..In all 4 trials, disease-free survival and overall survival were significantly improved with adjuvant trastuzumab (36%-52% and 33%-41%, respectively), and improvements were observed in all patient subgroups... - The role of the indispensable surgical pathologist in treatment planning for breast cancerDavid G Hicks
Arch Pathol Lab Med 132:1226-7. 2008 - Breast cancer risk reductionTherese B Bevers
National Comprehensive Cancer Network
J Natl Compr Canc Netw 5:676-701. 2007 - Production of murine monoclonal antibody to fetal hemoglobinYegneshwar S Iyer
Institute of Immunohaematology, Indian Council of Medical Research (ICMR, King Edward Memorial Hospital Campus, Parel, Mumbai, India
Hemoglobin 27:229-34. 2003..We have raised a murine monoclonal antibody to human Hb F, that accurately measures the number of F cells by flow cytometry. The antibody was found to be potent and specific for F cells...