Research Topics
| R N HardenSummaryAffiliation: Rehabilitation Institute of Chicago Country: USA Publications
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Detail Information
Publications
Treatment of complex regional pain syndrome: functional restorationR Norman Harden
Center for Pain Studies, Chicago, IL 60610, USA
Clin J Pain 22:420-4. 2006..Medications, interventions, and psychotherapy will be covered in other sections of this series...- Chronic neuropathic pain. Mechanisms, diagnosis, and treatmentR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
Neurologist 11:111-22. 2005.... - Prospective examination of pain-related and psychological predictors of CRPS-like phenomena following total knee arthroplasty: a preliminary studyR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, 345 E Superior St, Chicago, IL 60610, USA
Pain 106:393-400. 2003..There appears to be a modest utility for preoperative distress and pain in predicting CRPS signs and symptoms following TKA, although false positive rates are relatively high... - Topiramate for phantom limb pain: a time-series analysisR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago Northwestern University Medical School, Chicago, Illinois 60611, USA
Pain Med 6:375-8. 2005..This analysis supports a hypothesis that topiramate may be effective in reducing phantom limb pain, and suggests a definitive study is indicated... - Diagnosis of complex regional pain syndrome: signs, symptoms, and new empirically derived diagnostic criteriaR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, IL, USA
Clin J Pain 22:415-9. 2006..The review will also address issues of staging and subtyping the syndrome, as well as a discussion of the salient signs, symptoms, and tests appropriate for use in the diagnosis... - A clinical approach to complex regional pain syndromeR N Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
Clin J Pain 16:S26-32. 2000..To allow the deficiencies in the science to paralyze the clinical process is therapeutic nihilism, and not acceptable... - Signs and symptoms of the myofascial pain syndrome: a national survey of pain management providersR N Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Illinois 60611, USA
Clin J Pain 16:64-72. 2000..The goal of this study was to assess clinical consensus regarding whether myofascial pain syndrome (MPS) is a legitimate and distinct diagnosis as well as the signs and symptoms characterizing MPS... - Increased systemic catecholamines in complex regional pain syndrome and relationship to psychological factors: a pilot studyR Norman Harden
Rehabilitation Institute of Chicago, Center for Pain Studies, 446 E Ontario, Ste 1011, Chicago, IL 60611, USA
Anesth Analg 99:1478-85; table of contents. 2004..Definitive studies are needed to examine these hypotheses in detail... - Brain dynamics for perception of tactile allodynia (touch-induced pain) in postherpetic neuralgiaP Y Geha
Department of Physiology, Northwestern University, Feinberg School of Medicine, 5 120 Ward Building, 303 East Chicago Avenue, Chicago, IL 60611, USA
Pain 138:641-56. 2008..These results have important clinical implications regarding adequate therapy... - Conducting clinical trials to establish drug efficacy in chronic painR N Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University Medical School, Illinois 60610, USA
Am J Phys Med Rehabil 80:547-57. 2001..Involvement of a biostatistical consultant is recommended during all phases of clinical trials... - Prospective, randomized, single-blind, sham treatment-controlled study of the safety and efficacy of an electromagnetic field device for the treatment of chronic low back pain: a pilot studyR N Harden
Center for Pain Studies, Chicago, Illinois 60611, USA
Pain Pract 7:248-55. 2007..To evaluate the efficacy and safety of therapeutic electromagnetic fields (TEMF) on chronic low back pain. Secondary objectives included the investigation of the effects of TEMF on psychometric measures... - Botulinum toxin a in the treatment of chronic tension-type headache with cervical myofascial trigger points: a randomized, double-blind, placebo-controlled pilot studyR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, 446 E Ontario, Chicago, IL 60611, USA
Headache 49:732-43. 2009..To evaluate the efficacy of botulinum toxin A (BT-A) as a prophylactic treatment for chronic tension-type headache (CTTH) with myofascial trigger points (MTPs) producing referred head pain... - Cognitive factors influence outcome following multidisciplinary chronic pain treatment: a replication and extension of a cross-lagged panel analysisJ W Burns
Finch University of Health Sciences, The Chicago Medical School, Psychology Department, Building 51, 3333 Green Bay Road, Chicago, IL 60064, USA
Behav Res Ther 41:1163-82. 2003..Findings replicate those of a recent report regarding cross-lagged effects, and offer support that cognitive changes may indeed influence late-treatment changes in outcomes... - Chronic pain patients are impaired on an emotional decision-making taskA Vania Apkarian
Department of Physiology, Northwestern University Medical School, 303 E Chicago Avenue, Chicago, IL 60611, USA
Pain 108:129-36. 2004..Our evidence indicates that chronic pain is associated with a specific cognitive deficit, which may impact everyday behavior especially in risky, emotionally laden, situations... - Biofeedback in the treatment of phantom limb pain: a time-series analysisR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago Northwestern University Medical School, Chicago, 446 Ontario Street, Suite 1011, Chicago, Illinois 60611, USA
Appl Psychophysiol Biofeedback 30:83-93. 2005..Sensory descriptors of pain decreased more than the affective pain descriptors. These preliminary results provide some support for the use of biofeedback in the treatment of PLP and indicate the need for further, definitive study... - The brain in chronic CRPS pain: abnormal gray-white matter interactions in emotional and autonomic regionsPaul Y Geha
Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Neuron 60:570-81. 2008..These abnormalities encompass emotional, autonomic, and pain perception regions, implying that they likely play a critical role in the global clinical picture of CRPS... - Medication Quantification Scale Version III: internal validation of detriment weights using a chronic pain populationMichael Gallizzi
Center for Pain Studies, Rehabilitation Institute of Chicago, Northwestern University, Chicago, Illinois 60611, USA
Pain Pract 8:1-4. 2008..The MQS has been used as a unitary clinical and research outcome... - Validation of proposed diagnostic criteria (the "Budapest Criteria") for Complex Regional Pain SyndromeR Norman Harden
Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
Pain 150:268-74. 2010..Overall, results corroborate the validity of the Budapest Criteria and suggest they improve upon existing IASP diagnostic criteria for CRPS... - Do omega-6 and trans fatty acids play a role in complex regional pain syndrome? A pilot studyChristopher Ramsden
Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Pain Med 11:1115-25. 2010..The study aims to compare the omega-6 (n-6) and omega-3 (n-3) highly unsaturated fatty acids (HUFA), and trans fatty acid (trans FA) status of Complex Regional Pain Syndrome (CRPS) patients to pain-free controls... - Examining the cross-cultural validity of the english short-form McGill Pain Questionnaire using the matched moderated regression methodologyJennifer L Zinke
Northwestern University, Chicago, IL 60611, USA
Clin J Pain 26:153-62. 2010..The aims of this study were to examine the psychometric properties and the differential item functioning (DIF) of the short-form McGill Pain Questionnaire (SF-MPQ) to test the cultural differences in verbally based pain expression... - Brain activity for spontaneous pain of postherpetic neuralgia and its modulation by lidocaine patch therapyP Y Geha
Department of Physiology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Ave, Chicago, IL 60611, USA
Pain 128:88-100. 2007..The results show a specific brain activity pattern for PHN spontaneous pain, and implicate areas involved in emotions and reward as best reflecting changes in pain with treatment... - The placebo effect in acute headache management: ketorolac, meperidine, and saline in the emergency departmentR N Harden
Rehabilitation Institute of Chicago, IL 60611, USA
Headache 36:352-6. 1996..In addition, the use of a standard analgesic is necessary to demonstrate both assay sensitivity and magnitude of response to placebo... - Chronic pain and opiates: a call for moderationR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, IL 60611, USA
Arch Phys Med Rehabil 89:S72-6. 2008..OVERALL ARTICLE OBJECTIVE: To present the case for thoughtful attention and moderation in prescribing opioids to treat chronic pain conditions... - Chronic back pain is associated with decreased prefrontal and thalamic gray matter densityA Vania Apkarian
Department of Physiology and Institute of Neuroscience, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Neurosci 24:10410-5. 2004..Our results imply that CBP is accompanied by brain atrophy and suggest that the pathophysiology of chronic pain includes thalamocortical processes... - Chronic pain and the emotional brain: specific brain activity associated with spontaneous fluctuations of intensity of chronic back painMarwan N Baliki
Department of Physiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Neurosci 26:12165-73. 2006.... - Pharmacotherapy of complex regional pain syndromeR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois, USA
Am J Phys Med Rehabil 84:S17-28. 2005..As with most chronic pain syndromes, pharmacotherapy coupled with functional restoration and an interdisciplinary approach to treatment are essential to a successful outcome... - Residual limbs of amputees are significantly cooler than contralateral intact limbsR Norman Harden
The Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
Pain Pract 8:342-7. 2008..To test the hypothesis that distal residual limbs (DRLs) have significant vasomotor abnormalities... - Medication Quantification Scale Version III: update in medication classes and revised detriment weights by survey of American Pain Society PhysiciansR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Chicago, Illinois 60611, USA
J Pain 6:364-71. 2005..It computes a single numeric value for a patient's pain medication profile. This number can be used by both clinicians and researchers to track pain levels through a treatment course or research study... - Comparative measurement of pelvic floor pain sensitivity in chronic pelvic painFrank F Tu
Department of Obstetrics and Gynecology, Feinberg School of Medicine at Northwestern University, Chicago, Illinois, USA
Obstet Gynecol 110:1244-8. 2007..The present study was undertaken to estimate pelvic floor and vaginal pressure-pain detection thresholds both in women with pelvic pain and healthy women... - Hypoesthesia in the distal residual limb of amputeesR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, 446 E Ontario, Suite 1011, Chicago, IL 60611, USA
PM R 2:607-11. 2010..To test the emerging hypothesis that there is polymodal fiber degeneration/loss in distal residual limbs (DRL) of amputees... - Redirection of cutaneous sensation from the hand to the chest skin of human amputees with targeted reinnervationTodd A Kuiken
Neural Engineering Center for Artificial Limbs, Rehabilitation Institute of Chicago, Department of Physical Medicine and Rehabilitation, Northwestern University, 345 East Superior Street, Chicago, IL 60611, USA
Proc Natl Acad Sci U S A 104:20061-6. 2007.... - Proposed new diagnostic criteria for complex regional pain syndromeR Norman Harden
Rehabilitation Institute of Chicago, Northwestern University, Chicago, Illinois, USA
Pain Med 8:326-31. 2007..This update summarizes the latest international consensus group's action in Budapest, Hungary to approve and codify empirically validated, statistically derived revisions of the IASP criteria for CRPS... - A critical analysis of the tender points in fibromyalgiaR Norman Harden
Center for Pain Studies, Rehabilitation Institute of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Pain Med 8:147-56. 2007..To pilot methodologies designed to critically assess the American College of Rheumatology's (ACR) diagnostic criteria for fibromyalgia... - Current diagnosis and therapy of complex regional pain syndrome: refining diagnostic criteria and therapeutic optionsAllen W Burton
University of Texas MD Anderson Cancer Center, Department of Anestiology and Pain Medicine, 1400 Holcombe Boulavard 409, Houston, TX 77030, USA
Expert Rev Neurother 5:643-51. 2005..Thus, in spite of our evolving understanding of this neurologic disorder, in many cases complex regional pain syndrome remains difficult to diagnose and treat successfully... - Stages of change in readiness to adopt a self-management approach to chronic pain: the moderating role of early-treatment stage progression in predicting outcomeJohn W Burns
Department of Psychology, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Rd, North Chicago, IL 60064, USA
Pain 115:322-31. 2005..In contrast, late-treatment gains of patients initially taking a predominant precontemplation stance were unaffected by their degree of early-treatment attitude changes... - Diagnostic and treatment issues in postamputation pain after landmine injuryPhilip Wiffen
Oxford Pain Relief Unit, UK
Pain Med 7:S209-12. 2006 - Do changes in cognitive factors influence outcome following multidisciplinary treatment for chronic pain? A cross-lagged panel analysisJohn W Burns
Department of Psychology, Finch University of Health Sciences Chicago Medical School, Illinois 60064, USA
J Consult Clin Psychol 71:81-91. 2003..Findings advance understanding of pain treatment process and suggest that negative cognition changes may indeed affect improvements in treatment outcome... - Complex regional pain syndrome: are there distinct subtypes and sequential stages of the syndrome?Stephen Bruehl
Department of Anesthesiology, Vanderbilt University School of Medicine, Suite 403 G MAB, 1211 Twenty First Avenue South, Nashville, TN 37232 1557, USA
Pain 95:119-24. 2002..However, several distinct CRPS subtypes are suggested, and these could ultimately have utility in targeting treatment more effectively... - Neurophysiology of pain from landmine injuryAndre Muller
Centre d'Etude et Traitement de la Douleur, Hopital Civil, Strasbourg, France
Pain Med 7:S204-8. 2006