Research Topics
| Andrew L NilesSummaryAffiliation: Promega Corporation Country: USA Publications
| Collaborators |
Detail Information
Publications
A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markersAndrew L Niles
Promega Corp, Madison, WI 53711, USA
Anal Biochem 366:197-206. 2007..Ratiometric measurement of viable and dead cells in the same sample provides an internal control that can be used to normalize data from other cell-based assays...
Multiplex caspase activity and cytotoxicity assaysAndrew L Niles
Promega Corporation, Madison, WI, USA
Methods Mol Biol 414:151-62. 2008..Furthermore, multiplexing caspase activity assays with viability and/or cytotoxicity assays can support conclusions regarding cytotoxic mechanism and provide normalization that may help correct for differences in cell number...
Cytotoxicity testing: measuring viable cells, dead cells, and detecting mechanism of cell deathTerry L Riss
Promega Corporation, Madison, WI, USA
Methods Mol Biol 740:103-14. 2011..Data analysis from the measurement of three marker protease activities from the same sample provides a useful tool to help uncover the mechanism of cell death and can serve as an internal control to help identify assay artifacts...
In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screeningAndrew L Niles
Research Department, Promega Corporation, 2800 Woods Hollow Road, Madison, WI, USA
Curr Chem Genomics 3:33-41. 2009..Lastly, we discuss the advantages of combining specific HTS compatible assays into multi-parametric, same-well formats...
Caspase activity assaysAndrew L Niles
Promega Corporation, Madison, WI, USA
Methods Mol Biol 414:137-50. 2008..The highlighted techniques in this chapter are cost efficient and allow for the rapid exploration of thousands of combinations and conditions...
