Detail Information
Publications
Effect of rifampin on the pharmacokinetics of Axitinib (AG-013736) in Japanese and Caucasian healthy volunteersY K Pithavala
Pfizer Oncology, Pfizer Global Research and Development, La Jolla Laboratories, 101646 Science Center Drive, San Diego, CA 92121, USA
Cancer Chemother Pharmacol 65:563-70. 2010..Equal numbers of Japanese and Caucasian subjects were enrolled to assess the potential differences in axitinib pharmacokinetics between the two ethnicities...
Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteersYazdi K Pithavala
Pfizer Oncology, 10555 Science Center Drive, San Diego, CA 92121, USA
Invest New Drugs 30:273-81. 2012..This study evaluated changes in axitinib plasma pharmacokinetic parameters and assessed safety and tolerability in healthy subjects, following axitinib co-administration with the potent CYP3A inhibitor ketoconazole...
A Phase I study to evaluate the pharmacokinetics of axitinib (AG-13736) in healthy Chinese volunteersY Chen
Pfizer Oncology, San Diego, CA, USA, Peking Union Medical College Hospital, Pfizer, Beijing, China, and Pfizer Inc, New London, CT, USA
Int J Clin Pharmacol Ther 49:679-87. 2011..Axitinib pharmacokinetics in this population was similar to those previously observed in healthy Caucasians, suggesting a lack of ethnic differences...
