Nathan A Lacher

Summary

Affiliation: Pfizer Global Research and Development
Country: USA

Publications

  1. ncbi Development of a capillary gel electrophoresis method for monitoring disulfide isomer heterogeneity in IgG2 antibodies
    Nathan A Lacher
    Analytical R and D, Pfizer Biotherapeutics R and D, Chesterfield, MO, USA
    Electrophoresis 31:448-58. 2010
  2. ncbi Rapid and refined separation of human IgG2 disulfide isomers using superficially porous particles
    Qian Wang
    Analytical R and D, Global Biologics, Pfizer Inc, Chesterfield, MO 63017, USA
    J Sep Sci 33:2671-80. 2010
  3. ncbi Analysis of identity, charge variants, and disulfide isomers of monoclonal antibodies with capillary zone electrophoresis in an uncoated capillary column
    Yan He
    Analytical R and D, Pfizer BioTherapeutics R and D Pharmaceutical Sciences, 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, USA
    Anal Chem 82:3222-30. 2010
  4. ncbi Capillary gel electrophoresis with laser-induced fluorescence of plasmid DNA in untreated capillary
    Heidi J Holovics
    Analytical R and D, Pfizer BioTherapeutics Pharmaceutical Sciences R and D, Chesterfield, MO, USA
    Electrophoresis 31:2436-41. 2010
  5. ncbi Development, validation, and implementation of capillary gel electrophoresis as a replacement for SDS-PAGE for purity analysis of IgG2 mAbs
    Nathan A Lacher
    Analytical R and D, Pfizer Biotherapeutics R and D, Chesterfield, MO 63017, USA
    J Sep Sci 33:218-27. 2010

Collaborators

Detail Information

Publications5

  1. ncbi Development of a capillary gel electrophoresis method for monitoring disulfide isomer heterogeneity in IgG2 antibodies
    Nathan A Lacher
    Analytical R and D, Pfizer Biotherapeutics R and D, Chesterfield, MO, USA
    Electrophoresis 31:448-58. 2010
    ....
  2. ncbi Rapid and refined separation of human IgG2 disulfide isomers using superficially porous particles
    Qian Wang
    Analytical R and D, Global Biologics, Pfizer Inc, Chesterfield, MO 63017, USA
    J Sep Sci 33:2671-80. 2010
    ..g. capillary gel electrophoresis, peptide mapping, ion exchange chromatography, etc.) is being used to characterize disulfide isomers in the development of therapeutic IgG2 antibodies...
  3. ncbi Analysis of identity, charge variants, and disulfide isomers of monoclonal antibodies with capillary zone electrophoresis in an uncoated capillary column
    Yan He
    Analytical R and D, Pfizer BioTherapeutics R and D Pharmaceutical Sciences, 700 Chesterfield Parkway West, Chesterfield, Missouri 63017, USA
    Anal Chem 82:3222-30. 2010
    ..CZE methods using an uncoated capillary column offer a versatile, generic, and economical approach to the evaluation of identity, charge heterogeneity, and disulfide isoforms of IgG antibodies...
  4. ncbi Capillary gel electrophoresis with laser-induced fluorescence of plasmid DNA in untreated capillary
    Heidi J Holovics
    Analytical R and D, Pfizer BioTherapeutics Pharmaceutical Sciences R and D, Chesterfield, MO, USA
    Electrophoresis 31:2436-41. 2010
    ..In addition, the feasibility of using this method as a platform for varying sizes of plasmid was investigated...
  5. ncbi Development, validation, and implementation of capillary gel electrophoresis as a replacement for SDS-PAGE for purity analysis of IgG2 mAbs
    Nathan A Lacher
    Analytical R and D, Pfizer Biotherapeutics R and D, Chesterfield, MO 63017, USA
    J Sep Sci 33:218-27. 2010
    ....