Research Topics
| Jonathan L FrenchSummaryAffiliation: Pfizer Global Research and Development Country: USA Publications
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Detail Information
Publications
Bayesian methods for a three-state model for rodent carcinogenicity studiesJonathan L French
Biostatistics, Pfizer Global Research and Development, 50 Pequot Avenue, New London, Connecticut 06320, USA
Biometrics 58:906-16. 2002..We implement the model by analyzing data from a National Toxicology Program chronic rodent bioassay...
Generalized additive models for cancer mapping with incomplete covariatesJonathan L French
Biostatistics, Global Research and Development, Pfizer, Inc, 50 Pequot Avenue, New London, CT 06320, USA
Biostatistics 5:177-91. 2004..We illustrate our method through an analysis of cancer incidence data from Cape Cod, Massachusetts. These analyses demonstrate that standard complete-case methods can yield biased estimates of the spatial variation of cancer risk...
Central nervous system pharmacokinetics of the Mdr1 P-glycoprotein substrate CP-615,003: intersite differences and implications for human receptor occupancy projections from cerebrospinal fluid exposuresKarthik Venkatakrishnan
Department of Clinical Pharmacology, Pfizer Global Research and Development, Groton, Connecticut 06340, USA
Drug Metab Dispos 35:1341-9. 2007....
Longitudinal aggregate data model-based meta-analysis with NONMEM: approaches to handling within treatment arm correlationJae Eun Ahn
Global Pharmacometrics, Pfizer Inc, 50 Pequot Ave MS 6025 A2249, New London, CT 06320, USA
J Pharmacokinet Pharmacodyn 37:179-201. 2010..Models that included only treatment arm-level random effects were not superior in any scenario...
