Webb C Miller

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi Fast-evolving noncoding sequences in the human genome
    Christine P Bird
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK
    Genome Biol 8:R118. 2007
  2. ncbi Comparison of genomic DNA sequences: solved and unsolved problems
    W Miller
    Department of Computer Science and Engineering, Penn State, University Park, PA 16802, USA
    Bioinformatics 17:391-7. 2001
  3. ncbi A computer program for aligning a cDNA sequence with a genomic DNA sequence
    L Florea
    Department of Computer Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802 USA
    Genome Res 8:967-74. 1998
  4. ncbi Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights
    R Hardison
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park 16802, USA
    Gene 205:73-94. 1997
  5. ncbi Databases of human hemoglobin variants and other resources at the globin gene server
    R C Hardison
    Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802, USA
    Hemoglobin 25:183-93. 2001
  6. ncbi Aligning a DNA sequence with a protein sequence
    Z Zhang
    Department of Computer Science and Engineering, The Pennsylvania State University, University Park 16802, USA
    J Comput Biol 4:339-49. 1997
  7. ncbi Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement
    J M Molete
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Mol Cell Biol 21:2969-80. 2001
  8. ncbi Global predictions and tests of erythroid regulatory regions
    R C Hardison
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Cold Spring Harb Symp Quant Biol 68:335-44. 2003
  9. ncbi A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region
    L Elnitski
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Biol Chem 276:6289-98. 2001
  10. ncbi Association between divergence and interspersed repeats in mammalian noncoding genomic DNA
    F Chiaromonte
    Department of Statistics, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 98:14503-8. 2001

Collaborators

Detail Information

Publications10

  1. ncbi Fast-evolving noncoding sequences in the human genome
    Christine P Bird
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK
    Genome Biol 8:R118. 2007
    ..These conserved noncoding (CNC) sequences may well harbor critical regulatory variants that have driven recent human evolution...
  2. ncbi Comparison of genomic DNA sequences: solved and unsolved problems
    W Miller
    Department of Computer Science and Engineering, Penn State, University Park, PA 16802, USA
    Bioinformatics 17:391-7. 2001
    ..RESULTS: We sketch the current state of software for comparing genomic DNA sequences and outline research directions that we believe are likely to result in important advances in practice...
  3. ncbi A computer program for aligning a cDNA sequence with a genomic DNA sequence
    L Florea
    Department of Computer Science and Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802 USA
    Genome Res 8:967-74. 1998
    ..A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation...
  4. ncbi Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights
    R Hardison
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park 16802, USA
    Gene 205:73-94. 1997
    ..Multiple HS units (at least three: HS2, HS3 and HS4 cores plus flanking DNAs) together establish a chromatin structure that allows the proper developmental regulation of genes within the cluster...
  5. ncbi Databases of human hemoglobin variants and other resources at the globin gene server
    R C Hardison
    Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802, USA
    Hemoglobin 25:183-93. 2001
    ..These resources are reviewed in the context of a larger plan for providing related resources on hemoglobins, benign and pathological variation in these proteins and the genes that encode them, and the regulation of the globin genes...
  6. ncbi Aligning a DNA sequence with a protein sequence
    Z Zhang
    Department of Computer Science and Engineering, The Pennsylvania State University, University Park 16802, USA
    J Comput Biol 4:339-49. 1997
    ....
  7. ncbi Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement
    J M Molete
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Mol Cell Biol 21:2969-80. 2001
    ..The three targeted integration sites differ substantially in their permissivity for expression, but even the largest LCR construct tested could not overcome these position effects to confer equal expression at all three sites...
  8. ncbi Global predictions and tests of erythroid regulatory regions
    R C Hardison
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Cold Spring Harb Symp Quant Biol 68:335-44. 2003
  9. ncbi A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region
    L Elnitski
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Biol Chem 276:6289-98. 2001
    ..The novel negative element also functions after stable integration into MEL chromosomes. Smaller deletions at the 5' end of the HS2 core map the negative element within a 20-base pair region containing two conserved sequences...
  10. ncbi Association between divergence and interspersed repeats in mammalian noncoding genomic DNA
    F Chiaromonte
    Department of Statistics, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 98:14503-8. 2001
    ..The evidence presented here of correlated variation in the rates of different evolutionary processes across noncoding DNA must be considered in assessing such conservation for evidence of selection...